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Epidemiologische
Studie zu Chancen der Verhütung,
Früherkennung und
optimierten THerapie chronischer
ERkrankungen in der älteren Bevölkerung
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Publikationen
2020
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1)
Brandao A, Paulo P, Maia
S, Pinheiro M, Peixoto A,…, Brenner H,…, Roobol MJ, The Profile Study
Steering Committee, The PRACTICAL Consortium, Teixeira MR. The CHEK2 variant
c. 349A>G is associated with prostate cancer risk and carriers. Cancers
2020; 12:3254.
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2)
NCD Risk Factor
Collaboration (NCD-RisC). Height and body-mass index trajectories of
school-aged children and adolescents from 1985 to 2019 in 200 countries:
Pooled analysis of 2,182 population-based studies with 65 million
participants. Lancet 2020; 396:1511-1524.
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3)
Perna L, Zhang Y,
Matias-Garcia P, Ladwig KH, Wiechmann T, Wild B, Waldenberger M, Schöttker B,
Mons U, Ihle A, Kliegel M, Schwettmann L, Peters A, Brenner H. Subjective
mental health, incidence of depressive symptoms in later life, and the role
of epigenetics: results from two longitudinal cohort studies. Translational
Psychiatry 2020; 10:323.
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4)
Huynh-Le MP, Chieh Fan C, Karunamuni R, Walsh
EI, Turner EL,…, Brenner H,
Schöttker B, Holleczek B,…, Mills IG, Andreassen OA, Dale AM, Seibert
TM. A genetic risk score to personalize prostate cancer screening, applied
to population data. Cancer Epidemiology, Biomarkers & Prevention 2020;
29:1731-1738.
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5)
Konrad C, Lossnitzer N,
Boehlen FH, Haefeli WE, Holleczek B, Brenner H, Schöttker B, Wild B. Coping
resouces of heart failure patients – a comparison with cancer patients and
individuals having no chronic condition. Results from the ESTHER study. Heart
& Lung 2020; 49:829-835.
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6)
Brenner H, Holleczek B,
Schöttker B. Vitamin D insufficiency and deficiency and mortality from
respiratory diseases in a cohort of
older adults: potential for limiting the death toll during and beyond the
COVID-19 pandemic? Nutrients 2020; 12:E2488.
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7)
Ma J, Rebholz CM, Braun
KVE, Reynolds LM, Aslibekyan S,…, Zhang Y, Schöttker B, Brenner H,…, Hu FB,
Fornage M, Voortman T, Levy D. Whole blood DNA methylation signatures of diet
are associated with cardiovascular disease risk factors and all-cause
mortality. Circulation: Genomic and Precision Medicine 2020; 13:e002766.
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8)
Campa D, Gentiluomo M,
Obazee O, Ballerini A, Vodickova L,…, Brenner H,…, Schöttker B,…, Kaaks R, Neoptolemos J,
Lucchesi M, Canzian F. Genome-wide association study identifies an early
onset pancreatic cancer risk locus. International Journal of Cancer 2020;
147:2065-2074.
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9)
Yu H, Raut JR, Schöttker
B, Holleczek B, Zhang Y, Brenner H. Individual and joint contributions of
genetic and methylation risk scores for enhancing lung cancer risk
stratification: data from a population-based cohort in Germany. Clinical
Epigenetics 2020; 12:89.
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10)
NCD Risk Factor
Collaboration (NCD-RisC)*. Repositioning of the global epicenter of
non-optimal cholesterol. Nature 2020; 582:73-77. *Collaborators on behalf of
the ESTHER study: Brenner H, Saum KU, Schöttker B
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11)
Möllers T, Perna L,
Stocker H, Ihle P, Schubert I, Schöttker B, Frölich L, Brenner H. New use of
psychotropic medication after hospitalization among people with dementia.
International Journal of Geriatric Psychiatry 2020; 35:640-649.
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12)
Ochoa-Rosales C, ... ,
Muka T. Epigenetic link between statin therapy and type 2 diabetes. Diabetes
Care 2020; 43:875-884.
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13)
Vishram-Nielsen JKK, ... ,
on behalf of the MORGAM project. Does estimated pulse wave velocity add
prognostic information? The MORGAM prospective cohort project. Hypertension
2020; 75:1420-1428.
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14)
Kapoor PM, Lindström S,
Behrens S, , on behalf of the Breast Cancer Association Consortium.
Assessment of interactions between 205 breast cancer susceptibility loci and
13 established risk factors in relation to breast cancer risk in the Breast
Cancer Association Consortium. International Journal of Epidemiology 2020;
49:216-230.
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15)
Holleczek B, Schöttker B,
Brenner H. Helicobacter pylori infection, chronic atrophic gastritis and risk
of stomach and esophagus cancer: results
from the prospective population-based ESTHER cohort study. International
Journal of Cancer 2020; 146:2773-2783.
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16)
NCD Risk Factor
Collaboration (NCD-RisC). *National trends in total cholesterol obscure
heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL
cholesterol ratio: an analysis of trends in Asian and Western countries.
International Journal of Epidemiology 2020; 49:173-192. *Collaborators on
behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B
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17)
Yang Y, Wu L, ... , Long
J. Genetically predicted levels of DNA methylation biomarkers and breast
cancer risk: data from 228,951 women of European descent. Journal of the
National Cancer Institute 2020; 112:295-304.
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18)
Trares K, Gào X, Perna L,
Rujescu D, Stocker H, Möllers T, Beyreuther K, Brenner H, Schöttker B.
Associations of urinary 8-iso-prostaglandin F2α levels with all-cause
dementia, Alzheimer’s disease and vascular dementia incidence: results from a
prospective cohort study. Alzheimer’s & Dementia: The Journal of the Alzheimer’s
Association 2020; 16:804-813.
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19)
Boehlen FH, Herzog W,
Schellberg D, Maatouk I, Schöttker B, Brenner H, Wild B. Gender-specific
predictors of generalized anxiety disorder symptoms in older adults: results of a large population-based study.
Journal of Affective Disorders 2020; 262:174-181.
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20)
Anusruti A, Jansen EHJM,
Gào X, Xuan Y, Brenner H, Schöttker B. Longitudinal associations of body mass
index, waist circumference and waist to hip ratio with biomarkers of
oxidative stress in older adults: Results of a large cohort study. Obesity
Facts 2020; 13:66-76.
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21)
Anusruti A, Xuan Y, Gào X,
Jansen E, Laetsch DC, Brenner H, Schöttker B. Factors associated with high
oxidative stress in type 2 diabetes patients: a meta-analysis of two cohort
studies. BMJ Open Diabetes Research & Care 2020; 8:e000933.
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22)
Guo F, Chen C, Schöttker
B, Holleczek B, Hoffmeister M, Brenner H. Changes in colorectal cancer
screening use after introduction of alternative screening offer in Germany:
Prospective cohort study. International Journal of Cancer 2020;
146:2423-2432.
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23)
Barahona Ponce C, Scherer D, Boekstegers F, ...
, Brenner H, Schöttker B, Holleczek B,
et al. Arsenic and gallbladder cancer risk: Mendelian randomization analysis
of European prospective data. International Journal of Cancer 2020;
146:2648-2650.
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24)
Fachal L, Aschard H,
Beesley J, Barnes DR, Allen J,…, Brenner H,…, Schöttker B,…, Simard J, Easton
DF, Kraft P, Dunning AM. Fine-mapping of 150 breast cancer risk regions
identifies 191 likely target genes. Nature Genetics 2020; 52:56-73.
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25)
Schöttker B, Xuan Y, Gào
X, Anusruti A, Brenner H. Oxidatively damaged DNA/RNA and 8-isoprostane
levels are associated with the development of type 2 diabetes mellitus at
older age: results from a large cohort study. Diabetes Care 2020; 43:130-136.
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26)
Möllers T, Perna L,
Stocker H, Ihle P, Schubert I, Schöttker B, Frölich L, Bauer J, Brenner H.
Alzheimer’s disease medication and outcomes of hospitalization among patients
with dementia. Epidemiology and Psychiatric Sciences 2020; 29:e73, 1-9.
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27)
Guan Z, Raut JR, Weigl K,
Schöttker B, Holleczek B, Zhang Y, Brenner H. Individual and joint
performance of DNA methylation profiles, genetic risk scores and
environmental risk scores for predicting breast cancer risk. Molecular
Oncology 2020; 14:42-53.
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28)
Niersmann C,
Carstensen-Kirberg M, Maalmi H, Holleczek B, Roden M, Brenner H, Herder C,
Schöttker B. Higher circulating omentin is associated with increased risk of
primary cardiovascularevents in individuals with diabetes. Diabetologia 2020;
63:410-418.
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29)
Stocker H, Nabers A, Perna
L, Möllers T, Rujescu D, Hartmann A, Holleczek B, Schöttker B, Gerwert K,
Brenner H. Prediction of Alzheimer’s disease diagnosis within 14 years
through Aβ misfolding inblood plasma compared to APOE4 status, and other risk
factors. Alzheimer’s & Dementia: 2020; 16:283-291.
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30)
Gào X, Wilsgaard T, Jansen
EHJM, Yang X, Anusruti A, Brenner H, Schöttker B. Serum total thiol levels
and the risk of lung, colorectal, breast and prostate cancer: A prospective case-cohort study. International
Journal of Cancer 2020; 146:1261-1267.
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31)
Hilvo M, Meikle PJ, Pedersen ER, Tell GS, Dhar
I, Brenner H, Schöttker B, et al. Development and validation
of ceramide and phospholipid based cardiovascular risk estimation score for
coronary artery disease patients. European Heart Journal 2020; 41:371-380.
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2019
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32)
Brenner DR, ... , Straif K. Alcohol consumption and
lung cancer risk: A pooled analysis from the International Lung Cancer
Consortium and the SYNERGY study. Cancer Epidemiology 2019; 58:25-32.
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33)
Quinzler R, Freitag MH, Wiese B, Beyer M, Brenner H,
Dahlhaus A, Döring A, Freund T, Heier M, Knopf H, Luppa M, Prokein J,
Riedel-Heller SG, Schäfer I, Scheidt-Nave C, Scherer M, Schöttker B,
Szecsenyi J, Thürmann P, van den Bussche H, Gensichen J, Haefeli WE. A novel
superior medication-based chronic disease score predicted all-cause mortality
in independent geriatric cohorts. Journal of Clinical Epidemiology 2019;
105:112-124.
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34)
Hohls JK, Wild B, Heider D, Brenner H, Böhlen F,
Saum KU, Schöttker B, Matschinger H, Haefeli WE, König HH, Hajek A.
Association of generalized anxiety symptoms and panic with health care costs
in older age – Results from the ESTHER cohort study. Journal of Affective
Disorders 2019; 245:978-986.
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35)
Campa D, Matarazzi M, Greenhalf W, Bijlsma M, Saum
KU,…, Valsuani C, Vashist YK, Brenner H, Canzian F. Genetic determinants of
telomere length and risk of pancreatic cancer: a PANDoRA study. International
Journal of Cancer 2019; 144:1275-1283.
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36)
Schöttker B, Hagen L, Zhang Y, Gào X, Holleczek B,
Gao X, Brenner H. Serum 25-hydroxyvitamin D levels as an ageing marker.
Strong associations with age and all-cause mortality independent from
telomere length, epigenetic age acceleration and 8-isoprostane levels.
Journal of Gerontology: Medical Sciences 2019; 74:121-128.
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37)
Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal
L,…, Arndt V,…, Brenner H,…, Kraft P, Garcia-Closas M, Simard J, Easton DF.
Polygenic risk scores for prediction of breast cancer and breast cancer
subtypes. The American Journal of Human Genetics 2019; 104:21-34.
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38)
Travis RC, . . , Allen NE. A collaborative analysis
of individual participant data from 19 prospective studies assesses
circulating vitamin D and prostate cancer risk. Cancer Research 2019;
79:274-285.
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39)
Raina P, Gilsing A, Freisling H, van den Heuvel E,
Sohel N, Jenab M, Ferrari P, Tjonneland A, Benetou V, Picavet S, Eriksson S,
Schöttker B, Brenner H, Saum KU, Perna L, Wilsgaard T, Trichopoulou A,
Boffetta P, Griffith L. The combined effect of cancer and cardio-metabolic
conditions on the mortality burden in older adults. Journals of Gerontology:
Medical Sciences 2019; 74:366-372.
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40)
Wild B, Herzog W, Schellberg D, Böhlen F, Brenner H,
Saum KU, Maatouk I. A short intervention targeting psychosomatic care in
older adults with complex health care needs – results of a randomized
controlled trial. International Journal of Geriatric Psychiatry 2019;
34:272-279.
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41)
Gào X, Zhang Y, Burwinkel B, Xuan Y, Holleczek B,
Brenner H, Schöttker B. The associations of DNA methylation alterations in
oxidative stress related genes with cancer incidence and mortality outcomes:
A population-based cohort study. Clinical Epigenetics 2019; 11:14.
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42)
Böhlen F, Freigofas J, Herzog W, Meid A, Saum KU,
Schöttker B, Brenner H, Haefeli W, Wild B. Evidence for underuse and overuse
of antidepressants in older adults: Results of a large population-based
study. International Journal of Geriatric Psychiatry 2019; 34:539-547.
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43)
Xuan Y, Bobak M, Anusruti A, Jansen EHJM, Pajak A,
Tamosiunas A, Saum KU, Holleczek B, Gao X, Brenner H, Schöttker B.
Association of serum markers of oxidative stress with myocardinal infarction
and stroke: Pooled results from four large European cohort studies. European
Journal of Epidemiology 2019; 34:471-481.
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44)
Ferreira MA, Al-Ejeh F, Campa D, Gamazon E, Parsons
M,…, Arndt V, Brenner H,…, Caldés T, de la Hoya M, BCFR Investigators,
GC-HBOC Collaborators. Genome-wide association and transcriptome studies
identify target genes and risk loci for breast cancer. Nature Communications
2019; 10:1741.
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45)
Gao X, Gào X, Zhang Y, Holleczek B, Schöttker B,
Brenner H. Oxidative stress and epigenetic mortality risk score: associations
with all-cause mortality among elderly people. European Journal of
Epidemiology 2019; 34:451-462.
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46)
Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit
P,…, Arndt V,…, Brenner H,…, Thompson SG, Danesh J, Di Angelantonio E, Meade
T, for the Emerging Risk Factors Collaboration. Cardiovascular risk factors
associated with venous thromboembolism. JAMA Cardiology 2019; 4:163-173.
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47)
Di Credico G, Edefonti V, Polesel J, Pauli F,
Torelli N,…, Brenner H,…, Boffetta P, Hashibe M, Lee YCA, Dal Maso L. Joint
effects of intensity and duration of cigarette smoking on the risk of head
and neck cancer: a bivariate spline model approach. Oral Oncology 2019;
94:47-57.
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48)
Gào X, Wilsgaard T, Jansen EHJM, Holleczek B, Zhang
Y, Xuan Y, Anusruti A, Brenner H, Schöttker B. Pre-diagnostic derivatives of
reactive oxygen metabolites and the occurrence of lung, colorectal, breast
and prostate cancer: An individual participant data meta-analysis of two
large population-based studies. International Journal of Cancer 2019;
145:49-57.
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49)
Kar SP, Andrulis IL, Brenner H, Burgess S,
Chang-Claude J, Considine D, Dörk T, Evans GR, Gago-Dominguez M, Giles GG,
Hartman M, Huo D, Kaaks R, Li J, Lophatananon A, Margolin S, Milne RL, Muir
KR, Olsson H, Punie K, Radice P, Simard J, Tamimi RM, Van Nieuwenhuysen E,
Wendt C, Zheng W, Pharoah PDP. The association between weight at birth and
breast cancer risk revisited using Mendelian randomisation. European Journal
of Epidemiology 2019; 34:591-600.
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50)
Fiorito G, McCrory C, Robinson O, Carmeli C, Rosales
CO, Zhang Y,…, Brenner H,…, Elliot P, Stringhini S, Vineis P, Polidoro S, and
the Lifepath consortium. Socioeconomic position, lifestyle habits and
biomarkers of epigenetic aging: a multi-cohort analysis. Aging 2019;
11:2045-2070.
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51)
Gào X, Holleczek B, Cuk K, Zhang Y, Anusruti A, Xuan
Y, Xu Y, Brenner H, Schöttker B. Investigation on potential associations of
oxidatively generated DNA/RNA damage with lung, colorectal, breast, prostate
and total cancer incidence. Scientific Reports 2019; 9:7109.
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52)
NCD Risk Factor Collaboration (NCD-RisC). *Rising
rural body-mass index is the main driver of the global obesity epidemic in
adults. Nature 2019; 569:260-264. *Collaborators on behalf of the ESTHER
study: Brenner H, Saum KU, Schöttker B
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53)
Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF,…,
Brenner H,…, Schöttker B,…, Scholz M, Teumer A, Köttgen A, Pattaro C. A
catalog of genetic loci associated with kidney function from analyses of a
million individuals. Nature Genetics 2019; 51:957-972.
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54)
Obazee O, Archibugi L, Andriulli A, Soucek P,
Malecka-Panas E,…, Brenner H,…, Vodicka P, Tjaden C, Iskierka-Jazdzewska E,
Canzian F. Germline BRCA2 K3326X and CHEK2 I157T mutations
increase risk for sporadic pancreatic ductal adenocarcinoma. International
Journal of Cancer 2019; 145:686-693.
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55)
Khetan P, . , Hashim D. Occupations and the risk of
head and neck cancer: A pooled analysis of the International Head and Neck
Cancer Epidemiology (INHANCE) Consortium. Journal of Occupational and
Environmental Medicine 2019; 61:397-404.
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56)
Campa D, Martino A, Macauda A, Dudzinski M, Suska
A,…, Brenner H,…, Zaucha JM, Andersen V, Zawirska D, Canzian F. Genetic
polymorphisms in genes of class switch recombination and multiple myeloma
risk and survival: an IMMEnSE study. Leukemia and Lymphoma 2019;
60:1803-1811.
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57)
Perna L, Wahl HW, Weberpals J, Jansen L, Mons U,
Schöttker B, Brenner H. Incident depression and mortality among people with
different types of dementia: Results from a longitudinal cohort study. Social
Psychiatry and Psychiatric Epidemiology 2019; 54:793-801.
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58)
Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field
JK,…, Brenner H,…, Christiani DC, Amos CI, Yang P, Gorlova OY. Lung cancer
risk in never smokers of European descent is associated with genetic
variation in the 5P15. 33 TERT-CLPTM1L region. Journal of Thoracic Oncology
2019; 14:1360-1369.
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59)
Xuan Y, Gào X, Anusruti A, Holleczek B, Jansen EHJM,
Muhlack DC, Brenner H, Schöttker B. Association of serum markers of oxidative
stress with incident major cardiovascular events, cancer incidence and
all-cause mortality in type 2 diabetes patients: Pooled results from two
cohort studies. Diabetes Care 2019; 42:1436-1445.
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60)
Gào X, Xuan Y, Benner A, Anusruti A, Brenner H,
Schöttker B. Nitric oxide metabolites and lung cancer incidence: A matched
case-control study nested in the ESTHER cohort. Oxidative Medicine and
Cellular Longevity 2019; 6470950.
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61)
Shu X, Wu L, Khankari NK, Shu XO, Wang TJ,
Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah PDP,
Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W, Breast Cancer
Association Consortium*. Associations of obesity and circulating insulin and
glucose with breast cancer risk: a Mendelian randomization analysis.
International Journal of Epidemiology 2019; 48:795-806. *Co-authors on behalf
of the ESTHER study: Arndt V, Brenner H
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62)
The WHO CVD Risk Chart Working Group. *World Health
Organization (WHO) cardiovascular disease risk charts: revised models to
estimate risk in 21 global regions. The Lancet Global Health 2019;
7:e1332-1345. *Co-authors on behalf of the ESTHER study: Brenner H, Schöttker
B.
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63)
Shepshelovich D, . , Liu G. Body mass index (BMI),
BMI change, and overall survival in patients with SCLC and NSCLC: A pooled
analysis of the International Lung Cancer Consortium. Journal of Thoracic
Oncology 2019; 14:1594-1607.
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64)
Teumer A, Li Y, Ghasemi S, Prins B, Wuttke M,…,
Brenner H,…, Schöttker B,…, Kottgen A, Gerstner L, Chen M, Grundner-Culemann
F. Genome-wide association meta-analyses and fine-mapping elucidate pathways
influencing albuminuria. Nature Communications 2019; 10:4130.
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65)
Dörk T, Peterlongo P, Mannermaa A, Bolla MK, Wang
Q,…, Brenner H,…, Pharoah PDP, Schindler D, Devilee P, Easton DF. Two
truncating variants in FANCC and breast cancer risk. Scientific Reports 2019;
9:12524.
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66)
Hu C, Schöttker B, Venisse N, Limousi F, Saulnier
PJ, Albouy-Llaty M, Dupuis A, Brenner H, Migeot V, Hadjadj S. Bisphenol A, chlorinated
dervatives of Bisphenol A and occurrence of myocardinal infarction in
patients with type 2 diabetes: nested case-control studies in two European
cohorts. Environmental Science & Technology 2019; 53:9876-9883.
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67)
Ooi BNS, Loh H, Ho PJ, Milne R, Giles G, Gao C,
Kraft P, John EM, Swerdlow A, Brenner H, Wu AH, Haiman C, Evans DG, Zheng W,
Fasching P, Castelao JE, Kwong A, Xia S, Czene K, Hall P, Dunning A, Easton
DF, Hartman M, Li J. The genetic interplay between body mass index, breast
size and breast cancer risk: a Mendelian randomization analysis.
International Journal of Epidemiology 2019; 48:781-794.
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68)
Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X,…,
Brenner H,…, D’Agostino Sr RBD, Thompson SG, Danesh J, Di Angelantonio E, on
behalf of the Emerging Risk Factors Collaboration. Equalization of four
cardiovascular risk algorithms after systematic recalibration:
individual-participant meta-analysis of 86 prospective studies. European
Heart Journal 2019; 40:621-631.
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69)
Escala-Garcia M, Guo Q, Dörk T, Canisius S, Keeman
R,…, Arndt V,…, Brenner H,…, Holleczek B,…, Nevanlinna H, Eccles DM, Pharoah
PDP, Schmidt MK. Genome-wide association study of germline variants and
breast cancer-specific mortality. British Journal of Cancer 2019;
120:647-657.
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70)
Inker LA, Grams ME, Levey AS, Coresh J, Cirillo M,…,
Kovesdy CP, Woodward M, Levin A, CKD Prognosis Consortium. * Relationship of
estimated GFR and albuminuria to concurrent laboratory abnormalities: an
indivicual participant data meta-analysis in a global consortium. American
Journal of Kidney Diseases 2019; 73:206-217. *Collaborators on behalf of the
ESTHER study: Brenner H, Rothenbacher D, Schöttker B, Saum KU
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71)
Hohls JK, König HH, Heider D, Brenner H, Böhlen F,
Matschinger H, Saum KU, Schöttker B, Haefeli WE, Hajek A, Wild B.
Longitudinal association between panic disorder and health care costs in
older adults. Depress Anxiety 2019; 36:1135-1142.
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72)
Adams CD, Richmond R, Ferreira DLS, Spiller W, Tan
V,…, Brenner H,…, Pandha H, Thibodeau AN, Martin RM, PRACTICAL Consortium.
Circulating metabolic biomarkers of screen-detected prostate cancer in the
ProtecT Study. Cancer Epidemiology & Biomarkers 2019; 28:208-216.
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73)
Chang CP, Chang SC, Chuang SC, Berthiller J, Ferro
G,…, Brenner H,…, Boffetta P, Zhang ZF, Hashibe M, Lee YA. Age at start of
using tobacco on the risk of head and neck cancer: pooled analysis in the
International Head and Neck Cancer Epidemiology Consortium (INHANCE). Cancer
Epidemiology 2019; 63:101615.
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74)
Hoppe LK, Muhlack DC, Koenig W, Brenner H, Schöttker
B. The associations of diuretics and laxatives use with cardiovascular
mortality. An individual patient-data meta-analysis of two large cohort
studies. Cardiovascular Drugs and Therapy 2019; 33:567-579.
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75)
Figlioli G, Bogliolo M, Catucci I, Caleca L, Lasheras
SV,…, Arndt V,…, Brenner H,…, Couch F, Nevanlinna H, Surrallés J, Peterlongo
P. The FANCM:p. Arg658* truncating variant is associated with risk of
triple-negative breast cancer. npj Breast Cancer 2019; 5:38.
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76)
Brunner FJ, Waldeyer C, Ojeda F, Salomaa V, Kee F,…,
Brenner H,…, Omland T, Kuulasmaa K, Landmesser U, Blankenberg S. Application
of Non-HDL-Cholesterol for population-based cardiovascular risk
stratification. Results from the Multinational Cardiovascular Risk
Consortium. Lancet 2019; 394:2173-2183.
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2018
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77)
Campa D, Pastore M, Capurso G, Hackert T, Di Leo
M,…, Brenner H,…, Oliverius M, Pezzilli R, Landi S, Canzian F. Do pancreatic
cancer and chronic pancreatitis share the same genetic risk factors? A
PANcreatic Disease ReseArch (PANDoRA) consortium investigation. International
Journal of Cancer 2018; 142:290-296.
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78)
Seibert TM, Fan CC, Wang Y, Zuber V, Karunamuni R,…,
Brenner H,…, Andreassen OA, Dale AM, The PRACTICAL Consortium. Polygenic
hazard score to guide screening for aggressive prostate cancer: development
and validation in large-scale cohorts. BMJ 2018; 360:j5757.
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79)
Klein AP, Wolpin BM, Risch HA, Stolzenberg-Solomon RZ, Mocci E,…, Brenner
H,…, Chanock S, Obazee O, Petersen GM, Amundadottir TL. Genome-wide meta-analysis
identifies five new susceptibility loci for pancreatic cancer. Nature
Communications 2018; 9:556.
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80)
Ordóñez-Mena JM, ... , Brenner H, on behalf of the
Consortium on Health and Ageing: Network of Cohorts in Europe and the United
States (CHANCES). Impact of prediagnostic smoking and smoking cessation on
colorectal cancer prognosis: a meta-analysis of individual patient data from
cohorts within the CHANCES consortium. Annals of Oncology 2018; 29:472-483.
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81)
Hajek A, Bock JO, Saum KU, Matschinger H, Brenner H, Holleczek B, Haefeli
WE, Heider D, König HH. Frailty and health care costs – longitudinal results
of a prospective cohort study. Age and Ageing 2018; 47:233-241.
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82)
Wood AM, ... , for the Emerging Risk Factors
Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group. Risk thresholds for
alcohol consumption: combined analysis of individual-participant data for
599912 current drinkers in 83 prospective studies. Lancet 2018;
391:1513-1523.
|
83)
Vijayakrishnan J, ... , The PRACTICAL consortium*,
et al. Genome-wide association study identifies susceptibility loci for
B-cell childhood acute lymphoblastic leukemia. Nature Communications 2018;
9:1340. *Collaborator from DKFZ: Brenner H,
|
84)
Zhang Y, Saum KU, Schöttker B, Holleczek B, Brenner
H. Methylomic survival predictors, frailty, and mortality. Aging 2018;
10:339-357.
|
85)
Colombo M, Lòpez-Perolio I, Meeks HD, Caleca L,
Parsons M,…, Arndt V,…, Brenner H,…, Spurdle AB, Goldgar DE, de la Hoya M,
Radice P. The BRCA2 c. 68-7T>A variant is not pathogenic: a model for
clinical calibration of spliceogenicity. Human Mutation 2018; 39:729-741.
|
86)
Horne HN, Oh H, Sherman ME, Palakal M, Hewitt SM,…,
Brenner H,…, Van Leeuwen FF, Van’t Veer LJ, Garcia-Closas M, Figueroa JD.
E-cadherin breast tumor expression, risk factors and survival: Pooled
analysis of 5,933 cases from 12 studies in the Breast Cancer Association
Consortium. Scientific Reports 2018; 8:6574.
|
87)
Nabers A, Perna L, Lange J, Mons U, Schartner J,
Güldenhaupt J, Saum KU, Janelidze S, Holleczek B, Rujescu D, Hansson O,
Gerwert K, Brenner H. Amyloid blood biomarker detects alzheimer’s disease.
EMBO Molecular Medicine 2018; 10:e8763.
|
88)
Painter J, O’Mara T, Morris A, Cheng T, Gorman M,…,
Brenner H,…, Tomlinson I, Easton D, Thompson D, Spurdle A. Genetic overlap
between endometriosis and endometrial cancer: evidence from cross-disease
genetic correlation and GWAS meta-analyses. Cancer Medicine 2018;
7:1978-1987.
|
89)
Rudolph A, Song M, Brook MN, Milne RL, Mavaddat N,…,
Brenner H, Arndt V,…, Easton DF, Chatterjee N, Chang-Claude J, Garcia-Closas
M. Joint associations of a polygenic risk score and environmental risk
factors for breast cancer in the Breast Cancer Association Consortium.
International Journal of Epidemiology 2018; 47:526-536.
|
90)
Gao X, Zhang Y, Schöttker B, Brenner H. Vitamin D
status and epigenetic-based mortality risk score: strong independent and
joint prediction of all-cause mortality in a population-based cohort study.
Clinical Epigenetics 2018; 10:84.
|
91)
Dadaev T, Saunders E, Newcombe P, Anokian E,
Leongamornlert D,…, Brenner H,…, Haiman C, Eeles R, Conti D, Kote-Jarai Z.
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis
identifies candidate causal variants. Nature Communications 2018; 9:2256.
|
92)
Gào X, Brenner H, Holleczek B, Cuk K, Zhang Y,
Anusruti A, Xuan Y, Xu Y, Schöttker B. Urinary 8-isoprostane levels and
occurrence of lung, colorectal, prostate, breast and overall cancer: Results
from a large, population-based cohort study with 14 years of follow-up. Free
Radical Biology & Medicine 2018; 123:20-26.
|
93)
Abubakar M, ... , Brenner H, et al. Etiology of hormone receptor
positive breast cancer differs by levels of histologic grade and
proliferation. International Journal of Cancer 2018; 143:746-757.
|
94)
Hajek A, Bock JO, Saum KU, Schöttker B, Brenner H, Heider D, König HH.
Unterschiede in der Morbidität nach Krankenversichertenstatus im Alter. Das
Gesundheitswesen 2018; 80:551-556.
|
95)
O’Mara TA, Glubb DM, Amant F, Annibali D, Ashton K,…, Brenner H,…,
Tomlinson I, Easton DF, Spurdle AB, Thompson DJ. Identification of nine new
susceptibility loci for endometrial cancer. Nature Communications 2018;
9:3166.
|
96)
Shi J, Wu L, Zheng W, Wen W, Wang S, Shu X, Long J,
Shen CY, Wu PE, Saloustros E, Chang-Claude J, Brenner H, Shu XO, Cai Q.
Genetic evidence for the association between schizophrenia and breast cancer.
Journal of Psychiatry and Brain Science 2018; 3:7.
|
97)
Went M, Sud A, Försti A, Halvarsson BM, Weinhold
N,…, the PRACTICAL consortium*,…, Morgan GJ, Hemminki K, Nilsson B, Houlston
RS. Identification of multiple risk loci and regulatory mechnisms influencing
susceptibility to multiple myeloma. Nature Communications 2018; 9:3707.
*Collaborator from DKFZ: Brenner H
|
98)
Schumacher FR, Al Olama AA, Berndt SI, Benlloch S,
Ahmed M,…, Brenner H,…, Henderson BE, Kote-Jarai Z, Haiman CA, Eeles RA.
Association analyses of more than 140,000 men identify 63 new prostate cancer
susceptibility loci. Nature Genetics 2018; 50:928-936.
|
99)
Wu L, Shi W, Long J, Guo X, Michailidou K,... ,
Arndt V,…, Brenner H,…, Kraft P, Easton DF, Chenevix-Trench G, Zheng W. A
transcriptome-wide association study of 229,000 women identifies new
candidate susceptibility genes for breast cancer. Nature Genetics 2018;
50:968-978.
|
100)
Heinrichs SKM,…, Brenner H, et al. Evidence for PTGER4, PSCA and
MBOAT7 as risk genes for gastric cancer on the genome and transcriptome
level. Cancer Medicine 2018; 7:5057-5065.
|
101)
Gao X, Zhang Y, Mons U, Brenner H. Leukocyte
telomere length and epigenetic-based mortality risk score: associations with
all-cause mortality among older adults. Epigenetics 2018; 13:846-857.
|
102)
Matejcic M, Saunders E, Dadaev T, Brook M, Wang K,…,
Brenner H,…, Eeles R, Kote-Jarai Z, Conti D, Haiman C. Germline variation at
8q24 and prostate cancer risk in men of European ancestry. Nature
Communications 2018; 9:4616.
|
103)
NCD Risk Factor Collaboration (NCD-RisC)*.
Contributions of mean and shape of blood pressure distribution to worldwide
trends and variations in raised blood pressure: a pooled analysis of 1018
population-based measurement studies with 88. 6 million participants.
International Journal of Epidemiology 2018; 47:872-883i. *Collaborators on
behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B
|
104)
Muhlack DC, Hoppe LK, Stock C, Haefeli WE, Brenner
H, Schöttker B. The associations of geriatric syndromes and other patient
characteristics with the current and future use of potentially inappropriate
medications in a large cohort study. European Journal of Clinical
Pharmacology 2018; 74:1633-1644.
|
105)
Xuan Y, Gào X, Holleczek B, Brenner H, Schöttker B.
Prediction of myocardial infarction, stroke and cardiovascular mortality with
urinary biomarkers of oxidative stress: Results from a large cohort study.
International Journal of Cardiology 2018; 273:223-229.
|
106)
Lin HY, ... , the PRACTICAL consortium, Park JY.
AA9int: SNP interaction pattern search using non-hierarchical additive model
set. Bioinformatics 2018; 34:4141-4150.
|
107)
Parmar P, Lowry E, Cugliari G, Sudermann M, Wilson
R,…, Zhang Y,…, Schöttker B,…, Brenner H, Verweij N, Li S, Chambers JC,
Järvelin MR, Sebert S, for the GLOBAL Meth QTL consortium. Association of
maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes
in 18,212 adults. EBioMedicine 2018; 38:206-216.
|
|
2017
|
108)
Taylor AE, Martin RM, Geybels MS, Stanford JL, Shui
I, ... , Brenner H, ... . Investigating the possible causal role of coffee
consumption with prostate cancer risk and progression using Mendelian
randomization analysis. International Journal of Cancer 2017; 140:322-328.
|
109)
Brunner C, Davies NM, Martin RM, Eeles R, Easton
DF,…, Brenner H,…, Teixeira MR, Pandha H, the PRACTICAL Consortium, Zuccolo
L. Alcohol consumption and prostate cancer incidence and progression: a
Mendelian randomization study. Int J Cancer 2017; 140:75-85.
|
110)
Jankovic N, Geelen A, Winkels RM, Mwungura B, Fedirko V, ... ,
Brenner H, ... . Adherence to the WCRF/AICR dietary recommendations
for cancer prevention and risk of cancer in elderly from Europe and the
United States: A Meta-Analysis within the CHANCES project. Cancer
Epidemiology, Biomarkers and Prevention 2017; 26:136-144.
|
111)
Skender S, Böhm J, Schrotz-King P, Chang-Claude J, Siegel EM, Steindorf
K, Owen RW, Ose J, Hoffmeister M, Brenner H, Ulrich CM. Plasma 25-hydroxyvitamin D3 levels
in colorectal cancer patients and associations with physical activity. Nutrition
and Cancer 2017; 69:229-237.
|
112)
Zhang Y, Hapala J, Brenner H, Wagner W. Individual
CpG sites that are associated with age and life expectancy become
hypomethylated upon aging. Clinical Epigenetics 2017; 9:9.
|
113)
Katsoulis M, Benetou V, Karapetyan T, Feskanich D,
Grodstein F, Kymmer U, Eriksson S, Wilsgaard T, Jorgensen L, Ahmed L,
Schöttker B, Brenner H, Bellavia A, Wolk A, Kubinova R, Stegeman B, Bobak M,
Boffetta P, Trichopoulou A. Excess mortality after hip fractures in elderly
from Europe and United States: the CHANCES project. Journal of Internal
Medicine 2017; 281:300-310.
|
114)
Muhlack DC, Hoppe LK, Weberpals J, Brenner H,
Schöttker B. Association of potentially inappropriate medication at older age
with cardiovascular events and overall mortality: a systematic review and
meta-analysis of cohort studies. Journal of the American Medical Directors
Association 2017; 18:211-220.
|
115)
Saum KU, Schöttker B, Meid A, Holleczek B, Haefeli
W, Hauer K, Brenner H. Is polypharmacy associated with frailty in older people?
Results from the ESTHER Cohort Study. Journal of the American Geriatrics
Society 2017; 65:e27-e32.
|
116)
Gao X, Zhang Y, Saum KU, Schöttker B, Breitling LP,
Brenner H. Tobacco smoking and smoking-related DNA methylation are associated
with the development of frailty among older adults. Epigenetics 2017;
12:149-156.
|
117)
Fehringer G, Brenner DR, Zhang ZF, Lee YCA, Matsuo
K,…, Brenner H,…, Consonni D, Olsson A, Straif K, Hung RJ. Alcohol and lung
cancer risk among never smokers: a pooled analysis from the International
Lung Cancer Consortium and the SYNERGY study. International Journal of Cancer
2017; 140:1976-1984.
|
118)
Walter V, Jansen L, Knebel P, Chang-Claude J,
Hoffmeister M, Brenner H. Physical activity and survival of colorectal cancer
patients: population-based study from Germany. International Journal of Cancer
2017; 140:1985-1997.
|
119)
Hajek A, Bock J-O, Brenner H, Saum K-U, Matschinger H, Haefeli WE,
Quinzler R, Heider D, König H-H. Welche Faktoren beeinflussen die privaten
Zuzahlungen zu Gesundheitsleistungen im Alter? Ergebnisse einer
Längsschnittstudie. Das Gesundheitswesen 2017; 79:e18-e25.
|
120)
Berendsen A, Kang J, van de Rest O, Jankovic N, ... , Brenner H, ... . Association of adherence to a
healthy diet with cognitive decline in European and American older adults: a
meta-analysis within the CHANCES consortium. Dementia and Geriatric Cognitive
Disorders 2017; 43:215-227.
|
121)
Zhang Y, Wilson R, Heiss J, Breitling LP, Saum KU,
Schöttker B, Holleczek B, Waldenberger M, Peters A, Brenner H. DNA
methylation signatures in peripheral blood strongly predict all-cause
mortality. Nature Communications 2017; 8:14617.
|
122)
Zuber V, Bettella F, Witoelar A, PRACTICAL
Consortium*, CRUK GWAS, BCAC Consortium, TRICL Consortium, Andreassen OA,
Mills IG, Urbanucci A. Bromodomain protein 4 discriminates tissue-specific
super-enhancers containing disease-specific susceptibility loci in prostate
and breast cancer. BMC Genomics 2017; 18:270. *Collaborator from DKFZ:
Brenner H
|
123)
Steele CJ, Schöttker B, Marshall AH, Kouvonen A,
O’Doherty MG, Mons U, Saum KU, Boffetta P, Trichopoulou A, Brenner H*, Kee
F*. Education achievement and type 2 diabetes – What mediates the
relationship in older adults? Data from the ESTHER study: a population-based
cohort study. BMJ Open 2017; 0:e013569. *shared last authorship
|
124)
Mayer T, Meid AD, Saum KU, Brenner H, Schöttker B, Seidling HM, Haefeli
WE. Comparison
of nine instruments to calculate anticholinergic load in a large cohort of
older outpatients: association with cognitive and functional decline, falls,
and use of laxatives. American Journal of Geriatric Psychiatry 2017;
25:531-540.
|
125)
NCD Risk Factor Collaboration (NCD-RisC)*. Worldwide
trends in blood pressure from 1975 to 2015: a pooled analysis of 1,479
population-based measurement studies with 19. 1 million participants. The
Lancet 2017; 389:37-*Collaborators on behalf of the ESTHER study: Brenner H,
Saum KU.
|
126)
Ordóñez-Mena JM, Maalmi H, Schöttker B, Saum KU,
Holleczek B, Wang TJ, Burwinkel B, Brenner H. Genetic variants in the vitamin
D pathway, 25(OH)D levels, and mortality in a large population-based cohort
study. Journal of Clinical Endocrinology & Metabolism 2017; 102:470-477.
|
127)
Sluik D, Jankovic N, Hughes M, O’Doherty MG,
Schöttker B,…, Brenner H,…,. Alcoholic beverage preference and diabetes
incidence across Europe: the Consortium on Health and Ageing Network of
Cohorts in Europe and the United States (CHANCES) project. European Journal
of Clinical Nutrition 2017; 71:659-668.
|
128)
Lin HY, Chen DT, Huang PY, Liu YH, Ochoa A,…,
Brenner H,…, Pandha H, Lu YJ, the PRACTICAL consortium, Park JY. SNP
interaction pattern identifier (SIPI): An intensive search for SNP-SNP
interaction patterns. Bioinformatics 2017; 33:822-833.
|
129)
Freisling H, Arnold M, Soerjomataram I, O’Doherty M,
Ordóñez-Mena J, ... , Brenner H, ... . Comparison of general obesity and
measures of body fat distribution in older adults in relation to cancer risk:
meta-analysis of individual participant data of seven prospective cohorts in
Europe. British Journal of Cancer 2017; 116:1486-1497.
|
130)
Ben Khedher S, Neri M, Papadopoulos A, Christiani
DC, Diao N, ... , Brenner H, Saum KU, ... . Menstrual and reproductive
factors and lung cancer risk: A pooled analysis from the International Lung
Cancer Consortium (ILCCO). International Journal of Cancer 2017; 141:309-323.
|
131)
Muranen TA, Greco D, Blomqvist C, Aittomäki K, Khan
S,…, Brenner H, Arndt V,…, Dennis J, Easton DF, Schmidt MK, Nevanlinna H.
Genetic modifiers of CHEK2*1100delC associated breast cancer risk.
Genetics in Medicine 2017; 19:599-603.
|
132)
Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A,
Guidugli L,…, Arndt V,…, Brenner H,…, Goldgar DE, Carreira A, Vreeswijk MPG,
Couch FJ. BRCA2 hypomorphic missense variants confer moderate risks of breast
cancer. Cancer Research 2017; 77:2789-2799.
|
133)
Schöttker B, Saum KU, Muhlack DC, Hoppe LK,
Holleczek B, Brenner H. Polypharmacy and mortality: new insights from a large
cohort of older adults by detection of effect modification by multi-morbidity
and comprehensive correction of confounding by indication. European Journal
of Clinical Pharmacology 2017; 73:1041-1048.
|
134)
Brenner H, Jansen L, Saum KU, Holleczek B, Schöttker
B. Vitamin D supplementation trials aimed at reducing mortality have much
higher power when focusing on people with low serum 25-hydroxyvitamin D concentrations.
Journal of Nutrition 2017; 147:1325-1333.
|
135)
Gao X, Gào X, Zhang Y, Breitling LP, Schöttker B,
Brenner H. Associations of self-reported smoking, cotinine levels and
epigenetic smoking indicators with oxidative stress among older adults: a population-based
study. European Journal of Epidemiology 2017; 32:443-456.
|
136)
Thomas B, Matsushita K, Abate KH, Al-Aly Z, Ärnlöv
J,…, Brenner H,…, Schöttker B,…, Vos T, Global Burden of Disease 2013 GFR
Collaborators, CKD Prognosis Consortium, Global Burden of Disease
Genitourinary Expert Group. Global cardiovascular and renal outcomes of
reduced GFR. Journal of the American Society of Nephrology 2017;
28:2167-2179.
|
137)
Ordóñez-Mena JM, Schöttker B, Saum KU, Holleczek B,
Burwinkel B, Wang TJ, Brenner H. No association of vitamin D pathway genetic
variants with cancer risks in a population-based cohort of German older
adults. Cancer Epidemiology, Biomarkers & Prevention 2017; 26:1459-1461.
|
138)
Gao X, Thomsen H, Zhang Y, Breitling LP, Brenner H.
The impact of methylation quantitative trait loci (mQTLs) on active
smoking-related DNA methylation changes. Clinical Epigenetics 2017; 9:87.
|
139)
Bamia C, Orfanos P, Juerges H, Schöttker B, Brenner H... . Self-rated health and all-cause
and cause-specific mortality of older adults. Individual data meta-analysis
of prospective cohort studies participating in the CHANCES Consortium.
Maturitas 2017; 103:37-44.
|
140)
Lophatananon A, Stewart-Brown S, Kote-Jarai Z, Al
Olama AA, Benlloch Garcia S, ... , Brenner H, ... . , Height, selected genetic
markers and prostate cancer risk: results from the PRACTICAL consortium.
British Journal of Cancer 2017; 117:734-743.
|
141)
Matsushita K, Ballew SH, Coresh J, Arima H, Ärnlöv
J, ... . Measures of chronic kidney disease and risk of incident peripheral
artery disease: a collaborative meta-analysis of individual participant data.
Lancet Diabetes & Endocrinology 2017; 5:718-728. Collaborators from the
ESTHER study: Brenner H, Schöttker B, Rothenbacher D, Saum KU
|
142)
Meistere I, Werner S, Zayakin P, Siliņa K, Rulle U,
Pismennaja A, Šantare D, Kikuste I, Isajevs S, Leja M, Kupčinskas L,
Kupčinskas J, Jonaitis L, Wu CY, Brenner H, Linē A, Kalniņa Z. The prevalence
of cancer-associated autoantibodies in patients with gastric cancer and
progressive grades of premalignant lesions. Cancer Epidemiology, Biomarkers
& Prevention 2017; 26:1564-1574.
|
143)
Gu F, Zhang H, Hyland PL, Berndt S, Gapstur SM, ... , Brenner H, ... . Inherited variation in circadian
rhythm genes and risks of prostate cancer and three other cancer sites in
combined cancer consortia. International Journal of Cancer 2017;
141:1794-1802.
|
144)
Barrdahl M, Rudolph A, Hopper JL, Southey MC, Broeks
A,…, Brenner H, Arndt V,…, Garcia-Closas M, Easton DF, Milne RL, Chang-Claude
J. Gene-environment interactions involving functional variants: results from
the Breast Cancer Association Consortium. International Journal of Cancer
2017; 141:1830-1840.
|
145)
Gao X, Zhang Y, Brenner H. Associations of Helicobacter
pylori infection and chronic atrophic gastritis with accelerated
epigenetic ageing in older adults. British Journal of Cancer 2017;
117:1211-1214.
|
146)
Boehlen FH, Herzog W, Schellberg D, Maatouk I, Saum
KU, Brenner H, Wild B. Self-perceived coping resources of middle-aged and older
adults – results of a large population-based study. Aging and Mental Health
2017; 21:1303-1309.
|
147)
Maddock J, Zhou A, Cavadino A, Kuzma E, Bao Y,…,
Brenner H, Kumari M, Power C, Llewellyn DJ, Hyppönen E. Vitamin D and
cognitive function: A mendelian randomisation study. Scientific Reports 2017;
7:13230.
|
148)
Mons U, Müezzinler A, Schöttker B, Dieffenbach AK,
Butterbach K, Schick M, Peasey A, De Vivo I, Trichopoulou A, Boffetta P,
Brenner H. Leukocyte telomere length and all-cause, cardiovascular disease,
and cancer mortality: Results from individual participant-data meta-analysis
of two large prospective cohort studies. American Journal of Epidemiology
2017; 185:1317-1326.
|
149)
Dimitrakopoulou VI, ... , and TRICL-ILCCO.
Circulating vitamin D concentration and risk of seven cancers: Mendelian
randomization study. The BMJ 2017; 359:j4761.
|
150)
Michailidou K, Lindström S, Dennis J, Beesley J, Hui
S,…, Arndt V,…, Brenner H,…, Chenevix-Trench G, Simard J, Kraft P, Easton DF.
Association analysis identifies 65 new breast cancer risk loci. Nature 2017;
551:92-94.
|
151)
Brouckaert O, Rudolph A, Laenen A, Keeman R, Bolla
MK,…, Arndt V,…, Brenner H,…, Garcia-Closas M, Chang-Claude J, Lambrechts D,
Neven P. Reproductive profiles and risk of breast cancer subtypes: a
multi-center case-only study. Breast Cancer Research 2017; 19:119.
|
152)
Milne RL, Kuchenbaecker KB, Michailidou K, Beesley
J, Kar S,…, Arndt V,…, Brenner H,…, Chenevix-Trench G, Garcia-Closas M,
Schmidt MK, Antoniou AC, Simard J. Identification of ten variants associated
with risk of estrogen-receptor-negative breast cancer. Nature Genetics 2017;
49: 1767-1778
|
153)
Bock JO, Hajek A, Brenner H, Saum KU, Matschinger H, Haefeli WE,
Schöttker B, Quinzler R, Heider D, König HH. A longitudinal investigation of
willingness to pay for health insurance in Germany. Health Services Research
2017; 52:1099-1117.
|
154)
Papadimitriou N, Tsilidis KK, Orfanos P, Benetou V,
Ntzani EE, ... , Brenner H, Schöttker B, Saum KU, Holleczek B, ... . Burden
of hip fracture using disability-adjusted life-years: a pooled analysis of
prospective cohorts in the CHANCES consortium. Lancet Public Health 2017;
2:e239-246.
|
155)
NCD Risk Factor Collaboration (NCD-RisC). *Worldwide
trends in body-mass index, underweight, overweight, and obesity from 1975 to
2016: a pooled analysis of 2416 population-based measurement studies in 128.
9 million children, adolescents, and adults. The Lancet 2017; 390:2627-2642.
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU
|
|
2016
|
156)
Bock JO, König HH, Brenner H, Haefeli WE, Quinzler
R, Matschinger H, Saum KU, Schöttker B, Heider D. Associations of frailty
with health care costs - results of the ESTHER cohort study. BMC Health Serv
Res. 2016 Apr 14;16(1):128.
|
157)
Bock JO, Heider D, Matschinger H, Brenner H, Saum KU, Haefeli WE, Konig
HH. Willingness
to pay for health insurance among the elderly population in Germany. Eur J
Health Econ. 2016 Mar;17(2):149-58.
|
158)
Boehlen FH, Herzog W, Maatouk I, Saum KU, Brenner H,
Wild B. [Treatment preferences of elderly patients with mental disorders]. Z
Gerontol Geriatr. 2016 Feb;49(2):120-5. doi:10. 1007/s00391-015-0908-x.
|
159)
Bonilla C, Lewis SJ, Martin RM, […], Brenner H et al. Pubertal development and prostate
cancer risk: Mendelian randomization study in a population-based cohort. BMC
Med. 2016 Apr 4;14:66.
|
160)
Bonilla C, Lewis SJ, Rowlands MA, […], Brenner H et al. Assessing the role of insulin-like
growth factors and binding proteins in prostate cancer using Mendelian
randomization: Genetic variants as instruments for circulating levels. Int J
Cancer. 2016 Oct 1;139(7):1520-33.
|
161)
Breitling LP, Saum KU, Perna L, Schöttker B,
Holleczek B, Brenner H. Frailty is associated with the epigenetic clock but
not with telomere length in a German cohort. Clin Epigenetics. 2016;8:21.
|
162)
Breitling LP, Saum KU, Schöttker B, Holleczek B,
Herth FJ, Brenner H. Pneumonia in the Noninstitutionalized Older Population.
Dtsch Arztebl Int. 2016 Sep 16;113(37):607-14.
|
163)
Brück K, Stel VS, Gambaro G, […], Brenner H et al. European CKD Burden Consortium.
CKD Prevalence Varies across the European General Population. J Am Soc
Nephrol. 2016 Jul;27(7):2135-47.
|
164)
Bull CJ, Bonilla C, Holly JM, […], Brenner H et al.
Blood lipids and prostate cancer: a Mendelian randomization analysis. Cancer
Med. 2016 Jun;5(6):1125-36.
|
165)
Chen LS, Baker T, Hung RJ, Horton A, […], Brenner H
et al. Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays
Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A
Meta-Analysis. EBioMedicine. 2016 Sep;11:219-26.
|
166)
Chen XZ, Schöttker B, Castro FA, Chen H, Zhang Y,
Holleczek B, Brenner H. Association of helicobacter pylori infection and
chronic atrophic gastritis with risk of colonic, pancreatic and gastric
cancer: A ten-year follow-up of the ESTHER cohort study. Oncotarget. 2016 Mar
29;7(13):17182-93.
|
167)
Fehringer G, Kraft P, Pharoah PD, […], Brenner H et al. Cross-Cancer Genome-Wide Analysis
of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel
Pleiotropic Associations. Cancer Res. 2016 Sep 1;76(17):5103-14.
|
168)
Florath I, Butterbach K, Heiss J, Bewerunge-Hudler
M, Zhang Y, Schöttker B, Brenner H. Type 2 diabetes and leucocyte DNA
methylation: an epigenome-wide association study in over 1,500 older adults.
Diabetologia. 2016 Jan;59(1):130-8.
|
169)
Fuchs J, Scheidt-Nave C, Gaertner B, Dapp U, von
Renteln-Kruse W, Saum KU, Thorand B, Strobl R, Grill E. [Frailty in Germany:
status and perspectives : Results from a workshop of the German Society for
Epidemiology]. Z Gerontol Geriatr. 2016 Dec;49(8):734-42. doi:10.
1007/s00391-015-0999-4.
|
170)
Gao X, Mons U, Zhang Y, Breitling LP, Brenner H. DNA
methylation changes in response to active smoking exposure are associated
with leukocyte telomere length among older adults. Eur J Epidemiol. 2016
Dec;31(12):1231-41.
|
171)
Gao X, Zhang Y, Breitling LP, Brenner H. Tobacco
smoking and methylation of genes related to lung cancer development.
Oncotarget. 2016 Sep 13;7(37):59017-28.
|
172)
Gao X, Zhang Y, Breitling LP, Brenner H.
Relationship of tobacco smoking and smoking-related DNA methylation with
epigenetic age acceleration. Oncotarget. 2016 Jul 26;7(30):46878-89.
|
173)
Gusev A, Shi H, Kichaev G, Pomerantz M, […], Brenner
H et al. The PRACTICAL Consortium. Atlas of prostate cancer heritability in
European and African-American men pinpoints tissue-specific regulation. Nat Commun.
2016 Apr 7;7:10979.
|
174)
Hajek A, Bock JO, Saum KU, Schöttker B, Brenner H, Heider D, Konig HH. [Morbidity Differences by Health
Insurance Status in Old Age]. Gesundheitswesen. 2016 Jun 28.
|
175)
Kar SP, Beesley J, Amin Al Olama A, [... ], Brenner
H et al. The PRACTICAL Consortium. Genome-Wide Meta-Analyses of Breast,
Ovarian, and Prostate Cancer Association Studies Identify Multiple New
Susceptibility Loci Shared by at Least Two Cancer Types. Cancer Discov. 2016
Sep;6(9):1052-67.
|
176)
Khankari NK, Murff HJ, Zeng C, […], Brenner H et al. The PRACTICAL Consortium.
Polyunsaturated fatty acids and prostate cancer risk: a Mendelian
randomisation analysis from the PRACTICAL consortium. Br J Cancer. 2016 Aug
23;115(5):624-31.
|
177)
Lechner S, Herzog W, Boehlen F, Maatouk I, Saum KU,
Brenner H, Wild B. Control preferences in treatment decisions among older
adults - Results of a large population-based study. J Psychosom Res. 2016
Jul;86:28-33.
|
178)
Maatouk I, Herzog W, Bohlen F, Quinzler R, Lowe B,
Saum KU, Brenner H, Wild B. Association of hypertension with depression and
generalized anxiety symptoms in a large population-based sample of older
adults. J Hypertens. 2016 Sep;34(9):1711-20.
|
179)
Meid AD, Quinzler R, Groll A, Wild B, Saum KU, Schöttker B, Heider D,
Konig HH, Brenner H, Haefeli WE. Longitudinal evaluation of medication underuse in
older outpatients and its association with quality of life. Eur J Clin
Pharmacol. 2016 Jul;72(7):877-85.
|
180)
Muezzinler A, Mons U, Dieffenbach AK, Butterbach K,
Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier C, Brenner H.
Body mass index and leukocyte telomere length dynamics among older adults:
Results from the ESTHER cohort. Exp Gerontol. 2016 Feb;74:1-8. doi:10.
1016/j. exger. 2015. 11. 019.
|
181)
NCD Risk Factor Collaboration (NCD-RisC). Worldwide
trends in diabetes since 1980: a pooled analysis of 751 population-based
studies with 4. 4 million participants. Lancet. 2016 Apr
9;387(10027):1513-30.
|
182)
NCD Risk Factor Collaboration (NCD-RisC). Trends in
adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis
of 1698 population-based measurement studies with 19. 2 million participants.
Lancet. 2016 Apr 2;387(10026):1377-96.
|
183)
NCD Risk Factor Collaboration (NCD-RisC). A century
of trends in adult human height. Elife. 2016 Jul 26;5.
|
184)
O'Doherty MG, Cairns K, O'Neill V, Lamrock F,
Jorgensen T, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kuulasmaa K,
Boffetta P, Trichopoulou A, Kee F. Effect of major lifestyle risk factors,
independent and jointly, on life expectancy with and without cardiovascular
disease: results from the Consortium on Health and Ageing Network of Cohorts
in Europe and the United States (CHANCES). Eur J Epidemiol. 2016
May;31(5):455-68.
|
185)
Ordóñez-Mena JM, Schöttker B, Mons U, […], Brenner
H; Consortium on Health and Ageing: Network of Cohorts in Europe and the
United States (CHANCES). Quantification of the smoking-associated cancer risk
with rate advancement periods: meta-analysis of individual participant data
from cohorts of the CHANCES consortium. BMC Med. 2016 Apr 5;14(1):62.
|
186)
Ordonez-Mena JM, Schöttker B, Fedirko V, Jenab M,
Olsen A, Halkjaer J, Kampman E, de Groot L, Jansen E, Bueno-de-Mesquita HB,
Peeters PH, Siganos G, Wilsgaard T, Perna L, Holleczek B, Pettersson-Kymmer
U, Orfanos P, Trichopoulou A, Boffetta P, Brenner H. Pre-diagnostic vitamin D
concentrations and cancer risks in older individuals: an analysis of cohorts
participating in the CHANCES consortium. Eur J Epidemiol. 2016
Mar;31(3):311-23.
|
187)
Perna L, Mons U, Rujescu D, Kliegel M, Brenner H.
Apolipoprotein E e4 and Cognitive Function: A Modifiable Association Results
from Two Independent Cohort Studies. Dement Geriatr Cogn Disord.
2016;41(1-2):35-45.
|
188)
Perna L, Zhang Y, Mons U, Holleczek B, Saum KU,
Brenner H. Epigenetic age acceleration predicts cancer, cardiovascular, and
all-cause mortality in a German case cohort. Clin Epigenetics. 2016;8:64.
|
189)
Schmidt MK, Hogervorst F, van Hien R, […], Brenner H et al. Age- and Tumor Subtype-Specific
Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. J Clin Oncol. 2016
Aug 10;34(23):2750-60.
|
190)
Schöttker B, Rathmann W, Herder C, Thorand B,
Wilsgaard T, Njolstad I, Siganos G, Mathiesen EB, Saum KU, Peasey A, Feskens
E, Boffetta P, Trichopoulou A, Kuulasmaa K, Kee F, Brenner H. HbA1c levels in
non-diabetic older adults - No J-shaped associations with primary
cardiovascular events, cardiovascular and all-cause mortality after
adjustment for confounders in a meta-analysis of individual participant data
from six cohort studies. BMC Med. 2016 Feb 11;14:26.
|
191)
Schöttker B, Saum KU, Jansen EH, Holleczek B,
Brenner H. Associations of metabolic, inflammatory and oxidative stress
markers with total morbidity and multi-morbidity in a large cohort of older
German adults. Age Ageing. 2016 Jan;45(1):127-35.
|
192)
Shi J, Park JH, Duan J, Berndt ST, […], Brenner H et al. Winner's Curse Correction and
Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on
Genome-Wide Association Study Summary-Level Data. PLoS Genet. 2016
Dec;12(12):e1006493.
|
193)
Walter V, Jansen L, Hoffmeister M, Ulrich A, Roth W,
Blaker H, Chang-Claude J, Brenner H. Prognostic relevance of prediagnostic
weight loss and overweight at diagnosis in patients with colorectal cancer.
Am J Clin Nutr. 2016 Oct;104(4):1110-20.
|
194)
Walter V, Jansen L, Ulrich A, Roth W, Blaker H,
Chang-Claude J, Hoffmeister M, Brenner H. Alcohol consumption and survival of
colorectal cancer patients: a population-based study from Germany. Am J Clin
Nutr. 2016 Jun;103(6):1497-506.
|
195)
Zhang Y, Florath I, Saum KU, Brenner H.
Self-reported smoking, serum cotinine, and blood DNA methylation. Environ
Res. 2016 Apr;146:395-403.
|
|
2015
|
196)
Amin Al Olama A, Benlloch S, Antoniou AC, […],
Brenner H et al. Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational
Consortium, Using 25 Known Prostate Cancer Susceptibility Loci. Cancer
Epidemiol Biomarkers Prev. 2015 Jul;24(7):1121-9.
|
197)
Amin Al Olama A, Dadaev T, Hazelett DJ, […], Brenner H et al. Multiple novel prostate cancer
susceptibility signals identified by fine-mapping of known risk loci among
Europeans. Hum Mol Genet. 2015 Oct 1;24(19):5589-602.
|
198)
Benetou V, Orfanos P, Feskanich D, Michaelsson K,
Pettersson-Kymmer U, Ahmed LA, Peasey A, Wolk A, Brenner H, Bobak M,
Wilsgaard T, Schöttker B, Saum KU, Bellavia A, Grodstein F, Klinaki E,
Valanou E, Papatesta EM, Boffetta P, Trichopoulou A. Education, marital
status, and risk of hip fractures in older men and women: the CHANCES
project. Osteoporos Int. 2015 Jun;26(6):1733-46.
|
199)
Boehlen F, Herzog W, Quinzler R, Haefeli WE, Maatouk
I, Niehoff D, Saum KU, Brenner H, Wild B. Loneliness in the elderly is
associated with the use of psychotropic drugs. Int J Geriatr Psychiatry. 2015
Sep;30(9):957-64.
|
200)
Bozorgmehr K, Maier W, Brenner H, Saum KU, Stock C,
Miksch A, Holleczek B, Szecsenyi J, Razum O. Social disparities in Disease
Management Programmes for coronary heart disease in Germany: a
cross-classified multilevel analysis. J Epidemiol Community Health. 2015
Nov;69(11):1091-101.
|
201)
Bozorgmehr K, San Sebastian M, Brenner H, Razum O,
Maier W, Saum KU, Holleczek B, Miksch A, Szecsenyi J. Analysing horizontal
equity in enrolment in Disease Management Programmes for coronary heart
disease in Germany 2008-2010. Int J Equity Health. 2015 Mar 10;14:28.
|
202)
Cheng TH, Thompson D, Painter J, […], Brenner H et
al. Meta-analysis of genome-wide association studies identifies common
susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3
and TSHZ1. Sci Rep. 2015 Dec 1;5:17369.
|
203)
Davies NM, Gaunt TR, Lewis SJ, […], Brenner H et al. The effects of height and BMI on
prostate cancer incidence and mortality: a Mendelian randomization study in
20,848 cases and 20,214 controls from the PRACTICAL consortium. Cancer Causes
Control. 2015 Nov;26(11):1603-16.
|
204)
Day FR, Ruth KS, Thompson DJ, […], Brenner H et al.
The BCAC Breast Cancer Association Consortium. Large-scale genomic analyses
link reproductive aging to hypothalamic signaling, breast cancer
susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015 Nov;47(11):1294-303.
|
205)
Emrich IE, Pickering JW, Schöttker B, Lennartz CS,
Rogacev KS, Brenner H, Rothenbacher D, Holleczek B, Saum KU, Fliser D, Heine
GH. Comparison of the performance of 2 GFR estimating equations using
creatinine and cystatin C to predict adverse outcomes in elderly individuals.
Am J Kidney Dis. 2015 Apr;65(4):636-8.
|
206)
Freigofas J, Seidling HM, Quinzler R, Schöttker B, Saum KU, Brenner H,
Haefeli WE. Characteristics
of medication schedules used by elderly ambulatory patients. Eur J Clin
Pharmacol. 2015 Sep;71(9):1109-20.
|
207)
Laitinen VH, Rantapero T, Fischer D, Vuorinen EM,
Tammela TL, Wahlfors T, Schleutker J. The PRACTICAL Consortium. Fine-mapping
the 2q37 and 17q11. 2-q22 loci for novel genes and sequence variants
associated with a genetic predisposition to prostate cancer. Int J Cancer.
2015 May 15;136(10):2316-27.
|
208)
Meid AD, Quinzler R, Freigofas J, Saum KU, Schöttker B, Holleczek B,
Heider D, Konig HH, Brenner H, Haefeli WE. Medication Underuse in Aging
Outpatients with Cardiovascular Disease: Prevalence, Determinants, and
Outcomes in a Prospective Cohort Study. PLoS One. 2015;10(8):e0136339.
|
209)
Muezzinler A, Mons U, Dieffenbach AK, Butterbach K,
Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier C, Brenner H.
Smoking habits and leukocyte telomere length dynamics among older adults:
Results from the ESTHER cohort. Exp Gerontol. 2015 Oct;70:18-25.
|
210)
Muezzinler A, ... , Brenner H. Smoking and All-cause
Mortality in Older Adults: Results From the CHANCES Consortium. Am J Prev
Med. 2015 Nov;49(5):e53-e63.
|
211)
Painter JN, O'Mara TA, Batra J, […], Brenner H et
al. Fine-mapping of the HNF1B multicancer locus identifies candidate variants
that mediate endometrial cancer risk. Hum Mol Genet. 2015 Mar
1;24(5):1478-92.
|
212)
Perna L, Wahl HW, Mons U, Saum KU, Holleczek B,
Brenner H. Cognitive impairment, all-cause and cause-specific mortality among
non-demented older adults. Age Ageing. 2015 May;44(3):445-51.
|
213)
Saum KU, Dieffenbach AK, Jansen EH, Schöttker B,
Holleczek B, Hauer K, Brenner H. Association between Oxidative Stress and
Frailty in an Elderly German Population: Results from the ESTHER Cohort
Study. Gerontology. 2015;61(5):407-15.
|
214)
Schöttker B, Brenner H. Vitamin D as a Resilience
Factor, Helpful for Survival of Potentially Fatal Conditions: A Hypothesis
Emerging from Recent Findings of the ESTHER Cohort Study and the CHANCES
Consortium. Nutrients. 2015 May 6;7(5):3264-78.
|
215)
Schöttker B, Brenner H, Jansen EH, Gardiner J,
Peasey A, Kubinova R, Pajak A, Topor-Madry R, Tamosiunas A, Saum KU,
Holleczek B, Pikhart H, Bobak M. Evidence for the free radical/oxidative
stress theory of ageing from the CHANCES consortium: a meta-analysis of
individual participant data. BMC Med. 2015 Dec 15;13:300.
|
216)
Schöttker B, Saum KU, Jansen EH, Boffetta P,
Trichopoulou A, Holleczek B, Dieffenbach AK, Brenner H. Oxidative stress
markers and all-cause mortality at older age: a population-based cohort
study. J Gerontol A Biol Sci Med Sci. 2015 Apr;70(4):518-24.
|
217)
Schöttker B, Zhang Y, Heiss JA, Butterbach K, Jansen
EH, Bewerunge-Hudler M, Saum KU, Holleczek B, Brenner H. Discovery of a novel
epigenetic cancer marker related to the oxidative status of human blood.
Genes Chromosomes Cancer. 2015 Sep;54(9):583-94.
|
218)
Stegeman S, Amankwah E, Klein K, […], Brenner H et al. A Large-Scale Analysis of Genetic
Variants within Putative miRNA Binding Sites in Prostate Cancer. Cancer
Discov. 2015 Apr;5(4):368-79.
|
219)
Szulkin R, Karlsson R, Whitington T, […], Brenner H et al. Genome-wide association study of
prostate cancer-specific survival. Cancer Epidemiol Biomarkers Prev. 2015
Nov;24(11):1796-800.
|
220)
Szulkin R, Whitington T, Eklund M, […], Brenner H et al. Prediction of individual genetic
risk to prostate cancer using a polygenic score. Prostate. 2015
Sep;75(13):1467-74.
|
221)
Vart P, Bakker SJ, Schöttker B, de Zeeuw D,
Rothenbacher D, Brenner H, Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U,
Koenig W, Gansevoort RT. Relevance of correction for drift and day-to-day
variation in cystatin C measurement: a post-hoc analysis of the PREVEND
cohort, with independent replication in the ESTHER cohort. Clin Chem Lab Med.
2015 Aug;53(9):1381-90.
|
222)
Walter V, Jansen L, Hoffmeister M, Ulrich A,
Chang-Claude J, Brenner H. Smoking and survival of colorectal cancer
patients: population-based study from Germany. Int J Cancer. 2015 Sep
15;137(6):1433-45. doi:10. 1002/ijc. 29511.
|
223)
Winn DM, Lee YC, Hashibe M, Boffetta P. The INHANCE
consortium: toward a better understanding of the causes and mechanisms of
head and neck cancer. Oral Dis. 2015 Sep;21(6):685-93.
|
224)
Zhang Y, Schöttker B, Ordonez-Mena J, Holleczek B,
Yang R, Burwinkel B, Butterbach K, Brenner H. F2RL3 methylation, lung cancer
incidence and mortality. Int J Cancer. 2015 Oct 1;137(7):1739-48.
|
|
2014
|
225)
Agarwal D, Pineda S, Michailidou K, [... ], Brenner H, Dieffenbach AK,
Arndt V, Stegmaier C et al. FGF receptor genes and breast cancer susceptibility:
results from the Breast Cancer Association Consortium. Br J Cancer. 2014 Feb
18; 110(4): 1088–1100. Published online 2014 Feb 18.
|
226)
Al Olama AA, Kote-Jarai Z, Berndt SI, […], Brenner H et al. A meta-analysis of 87,040
individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet.
2014 Oct;46(10):1103-9.
|
227)
Bock JO, Matschinger H, Brenner H, Wild B, Haefeli WE, Quinzler R, Saum
KU, Heider D, König HH. Inequalities in out-of-pocket payments for health
care services among elderly Germans--results of a population-based
cross-sectional study. Int J Equity Health. 2014 Jan 8;13(1):3.
|
228)
The Emerging Risk Factors Collaboration*. Glycated
hemoglobin measurement and prediction of cardiovascular disease. JAMA. 2014
Mar 26;311(12):1225-33. doi: 10. 1001/jama. 2014. 1873. Authors on behalf of
the ESTHER study: Brenner H.
|
229)
Florath I, Butterbach K, Muller H, Bewerunge-Hudler
M, Brenner H. Cross-sectional and longitudinal changes in DNA methylation
with age: an epigenome-wide analysis revealing over 60 novel age-associated
CpG sites. Hum Mol Genet. 2014 Mar 1;23(5):1186-201.
|
230)
Hazelett DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL,
Coetzee SG, Henderson BE, Noushmehr H, Cozen W, Kote-Jarai Z, Eeles RA,
Easton DF, Haiman CA, Lu W, Farnham PJ, Coetzee GA. The PRACTICAL Consortium.
Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet.
2014 Jan;10(1):e1004102.
|
231)
Heider D, Matschinger H, Müller H, Saum KU, Quinzler R, Haefeli WE, Wild
B, Lehnert T, Brenner H, König HH. Health care costs in the elderly in Germany: an
analysis applying Andersen's behavioral model of health care utilization. BMC
Health Serv Res. 2014 Feb 14;14:71.
|
232)
Jansen L, Hoffmeister M, Arndt V, Chang-Claude J,
Brenner H. Stage-specific associations between beta blocker use and prognosis
after colorectal cancer. Cancer. 2014 Apr 15;120(8):1178-86.
|
233)
Koch L, Bertram H, Eberle A, Holleczek B,
Schmid-Hopfner S, Waldmann A, Zeissig SR, Brenner H, Arndt V. Fear of
recurrence in long-term breast cancer survivors-still an issue. Results on
prevalence, determinants, and the association with quality of life and
depression from the cancer survivorship--a multi-regional population-based
study. Psychooncology. 2014 May;23(5):547-54.
|
234)
Leoncini E, Ricciardi W, Cadoni G, […], Brenner H et al. Adult height and head and neck
cancer: a pooled analysis within the INHANCE Consortium. Eur J Epidemiol.
2014 Jan;29(1):35-48.
|
235)
Milne RL, Herranz J, Michailidou K, […], Brenner H et al. A large-scale assessment of
two-way SNP interactions in breast cancer suceptibility using 46. 450 cases
and 42. 461 controls from the Breast Cancer Association Consortium. Hum Mol
Genet. 2014 Apr 1;23(7):1934-46.
|
236)
O'Doherty MG, ... , Brenner H, Schöttker B, ... ,
Kee F. Repeated measures of body mass index and C-reactive protein in
relation to all-cause mortality and cardiovascular disease: results from the
consortium on health and ageing network of cohorts in Europe and the United
States (CHANCES). Eur J Epidemiol. 2014 Dec;29(12):887-97. doi:10.
1007/s10654-014-9954-8.
|
237)
Pennells L, Kaptoge S, White IR, Thompson SG, Wood
AM; Emerging Risk Factors Collaboration. Assessing risk prediction models
using individual participant data from multiple studies. Am J Epidemiol. 2014
Mar 1;179(5):621-32.
|
238)
Perna L, Mons U, Kliegel M, Brenner H. Serum
25-hydroxyvitamin D and cognitive decline: a longitudinal study among
non-demented older adults. Dement Geriatr Cogn Disord. 2014;38(3-4):254-63.
|
239)
Saum KU, Dieffenbach AK, Müezzinler A, Müller H,
Holleczek B, Stegmaier C, Butterbach K, Schick M, Canzian F, Stammer H,
Boukamp P, Hauer K, Brenner H. Frailty and telomere length: Cross-sectional
analysis in 3537 older adults from the ESTHER cohort. Exp Gerontol. 2014 Aug
21;58C:250-255. .
|
240)
Saum KU, Dieffenbach AK, Muller H, Holleczek B,
Hauer K, Brenner H. Frailty prevalence and 10-year survival in
community-dwelling older adults: results from the ESTHER cohort study. Eur J
Epidemiol. 2014 Mar;29(3):171-9.
|
241)
Saunders EJ, Dadaev T, Leongamornlert DA, […], Brenner H et al. Fine-mapping the HOXB region
detects common variants tagging a rare coding allele: evidence for synthetic
association in prostate cancer. PLoS Genet. 2014 Feb;10(2):e1004129.
|
242)
Schoeps A, Rudolph A, Seibold P, […], Brenner H et
al. Identification of new genetic susceptibility loci for breast cancer
through consideration of gene-environment interactions. Genetic Epidemiology
2014; 38: 84-93.
|
243)
Schöttker B, Saum KU, Perna L, Ordonez-Mena JM,
Holleczek B, Brenner H. Is vitamin D deficiency a cause of increased
morbidity and mortality at older age or simply an indicator of poor health?
Eur J Epidemiol. 2014 Mar;29(3):199-210.
|
244)
Wen CP, . . , and the Chronic Kidney Disease
Prognosis Consortium. Relative risks of chronic kidney disease for mortality
and end-stage renal disease across races are similar. Kidney Int. 2014 Feb
12. doi: 10. 1038/ki. 2013. 553.
|
245)
Wild B, Eckl A, Herzog W, Niehoff D, Lechner S,
Maatouk I, Schellberg D, Brenner H, Muller H, Lowe B. Assessing generalized
anxiety disorder in elderly people using the GAD-7 and GAD-2 scales: results
of a validation study. Am J Geriatr Psychiatry. 2014 Oct;22(10):1029-38.
|
246)
Wild B, Heider D, Maatouk I, Slaets J, Konig HH,
Niehoff D, Saum KU, Brenner H, Sollner W, Herzog W. Significance and costs of
complex biopsychosocial health care needs in elderly people: results of a
population-based study. Psychosom Med. 2014 Sep;76(7):497-502.
|
247)
Zhang Y, Yang R, Burwinkel B, Breitling LP, Brenner
H. F2RL3 methylation as a biomarker of current and lifetime smoking
exposures. Environmental Health Perspectives 2014; 122: 131-137.
|
|
2013
|
248)
Perna L, Schöttker B, Holleczek B, Brenner H. Serum
25-hydroxyvitamin D and incidence of fatal and non-fatal cardiovascular
events: a prospective study with repeated measurements. Journal of Clinical
Endocrinology & Metabolism 2013; 98: 4908-4915.
|
249)
Perna L, Hoffmeister M, Schöttker B, Arndt V, Haug
U, Holleczek B, Burwinkel B, Ordonez-Mena JM, Brenner H. Vitamin D receptor
polymorphism and colorectal cancer-specific and all-cause mortality. Cancer
Epidemiology 2013; 37: 905-907.
|
250)
Silbernagel G, Schöttker B, Appelbaum S, Scharnagl
H, Kleber ME, Grammer TB, Ritsch A, Mons U, Holleczek B, Goliasch G, Niessner
A, Boehm BO, Schnabel RB, Brenner H, Blankenberg S, Landmesser U, März W.
High-density lipoprotein cholesterol, coronary artery disease and
cardiovascular mortality. European Heart Journal 2013; 34: 3563-71.
|
251)
Breitling LP, Olsen H, Müller H, Schöttker B,
Kliegel M, Brenner H. Self- or physician-reported diabetes, glycemia markers,
and cognitive functioning in older adults in Germany. American Journal of
Geriatric Psychiatry 2013; S1064-7481(13)00282-0.
|
252)
Wild B, Eckl A, Herzog W, Niehoff D, Lechner S,
Maatouk I, Schellberg D, Brenner H, Müller H, Löwe B. Assessing generalized
anxiety disorder in elderly people by use of the GAD-7 and GAD-2 scales -
results of a validation study. American Journal of Geriatric Psychiatry 2013;
S1064-7481(13)00116-4.
|
253)
Matsushita K, Ballew SH, Astor BC, de Jong PE,
Gansevoort RT, Hemmelgarn BR, Levey AS, Levin A, Wen C-P, Woodward M, Coresh
J, and for the CKD Prognosis Consortium*. Cohort profile: the chronic kidney
disease prognosis consortium. International Journal of Epidemiology 2013; 42:
1660-1668. *Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Müller H, Schöttker B.
|
254)
Yin L, Ordonez-Mena JM, Chen T, Schöttker B, Arndt
V, Brenner H. Circulating 25-hydroxyvitamin D serum concentration and total
cancer incidence and mortality: a systematic review and meta-analysis.
Preventive Medicine 2013; 57: 753-764.
|
255)
Schöttker B, Brenner H, Koenig W, Müller H,
Rothenbacher D. Prognostic association of HbA1c and fasting plasma glucose
with reduced kidney function in subjects with and without diabetes mellitus.
Results from a population-based cohort study from Germany. Preventive
Medicine 2013; 57: 596-600.
|
256)
Singh GM, ... , Emerging risk Factor Collaboration
(ERFC)*, Prospective Studies Collaboration (PSC). The age-specific quantitative
effects of metabolic risk factors on cardiovascular diseases and diabetes: A
pooled analysis. PloS One 2013; 8:e65174. *Authors on behalf of the ESTHER
study: Brenner H, Schöttker B, Müller H, Rothenbacher D.
|
257)
Mons U, Schöttker B, Müller H, Kliegel M, Brenner H.
History of lifetime smoking, smoking cessation and cognitive function in the
elderly population. European Journal of Epidemiology 2013; 28:823-831.
|
258)
Pesatori AC, Carugno M, Consonni D, Hung RJ,
Papadoupolos A, Landi M, Brenner H, Müller H, Harris C, Duell E, Andrew A,
McLaughlin J, Schwartz AG, Wenzlaff A, Stucker I. Hormone use and risk for
lung cancer: a pooled analysis from the International Lung Cancer Consortium
(ILCCO). British Journal of Cancer 2013; 109:1954-1964.
|
259)
Yu OH, Foulkes WD, Dastani Z, Martin RM, Eeles R,
PRACTICAL Consortium*, CRUK GWAS Investigators, Richards JB. An assessment of
the shared allelic architecture between type II diabetes and prostate cancer.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22:1473-1475. *Author
on behalf of the ESTHER study: Brenner H.
|
260)
Gellert C, Schöttker B, Müller H, Holleczek B,
Brenner H. Impact of smoking and quitting on cardiovascular outcomes and risk
advancement periods among older adults. European Journal of Epidemiology
2013; 28:648-658.
|
261)
Shlipak MG, Matsushita K, Ärnlöv J, Inker LA, Katz
R, Polkinghorne K, Rothenbacher D, Sarnak MJ, Astor BC, Coresh J, Levey AS,
Gansevoort RT, for the CKD Prognosis Consortium. *
|
262)
Cystatin C versus creatinine for determining risk
based on kidney function. New England Journal of Medicine 2013; 369:932-943.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Schöttker
B, Koenig W.
|
263)
Kote-Jarai Z, ... ; PRACTICAL Consortium, Easton DF,
Eeles RA. Fine-mapping identifies multiple prostate cancer risk loci at 5p15,
one of which associates with TERT expression. Human Molecular
Genetics 2013; 22: 2520-2528.
|
264)
Ordóñez-Mena JM, Schöttker B, Haug U, Müller H,
Köhrle J, Schomburg L, Holleczek B, Brenner H. Serum 25-hydroxyvitamin D and
cancer risk in older adults. Results from a large German prospective cohort
study. Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 905-916.
|
265)
Zhang Y, Weck MN, Schöttker B, Rothenbacher D,
Brenner H. Gastric parietal cell antibodies, Helicobacter pylori infection,
and chronic atrophic gastritis: Evidence from a large population-based study
in Germany. Cancer Epidemiology, Biomarkers & Prevention 2013; 22:
821-826.
|
266)
Shen H, ... ; PRACTICAL Consortium, ... , Pearce CL.
Epigenetic analysis leads to identification of HNF1B as a subtype-specific
susceptibility gene for ovarian cancer. Nature Communications 2013; 4:1628.
Doi: 10. 1038/ncomms2629. * Author on behalf of the ESTHER study: Brenner H.
|
267)
Eeles RA, ... ; PRACTICAL Consortium, Kote-Jarai Z,
Easton DF. Identification of 23 new prostate cancer susceptibility loci using
the iCOGS custom genotyping array. Nature Genetics 2013; 45: 385-391.
|
268)
Bojesen SE, ... , Dunning AM. Multiple independent
variants at the TERT locus are associated with telomere length and risks of
breast and ovarian cancer. Nature Genetics 2013; 45: 371-384.
|
269)
Michailidou K, ... , Easton DF. Large-scale
genotyping identifies 41 new loci associated with breast cancer risk. Nature
Genetics 2013; 45: 353-361.
|
270)
French JD, ... F, Dunning AM. Functional variants at
the 11q13 risk locus for breast cancer regulate Cyclin D1 expression through
long-range enhancers. American Journal of Human Genetics 2013; 92: 489-503.
|
271)
Nickels S, ... , Chang-Claude J. Evidence of
gene-environment interactions between common breast cancer susceptibility
loci and established environmental risk factors. PLoS Genetics 2013; 9:
e1003284.
|
272)
Schöttker B, Herder C, Rothenbacher D, Perna L,
Müller H, Brenner H. Serum 25-hydroxyvitamin D levels and incident diabetes
mellitus type 2. A competing risk analysis in a large population-based cohort
of older adults. European Journal of Epidemiology 2013; 28: 267-275.
|
273)
Schöttker B, Haug U, Schomburg L, Köhrle J, Perna L,
Müller H, Holleczek B, Brenner H. Strong associations of 25-hydroxyvitamin D
levels with all-cause, cardiovascular, cancer and respiratory disease
mortality in a large cohort study. The American Journal of Clinical Nutrition
2013; 97: 782-793.
|
274)
Perna L, Butterbach K, Haug U, Schöttker B, Müller
H, Arndt V, Holleczek B, Burwinkel B, Brenner H. Vitamin D receptor genotype
rs731236 (Taq1) and breast cancer prognosis. Cancer Epidemiology, Biomarkers
& Prevention 2013; 22: 437-442.
|
275)
Nitsch D, Grams M, Sang Y, Black C, Cirillo M,
Djurdjev O, Iseki K, Jassal SK, Kimm H, Kronenberg F, Øien CM, Levey AS,
Levin A, Woodward M, Hemmelgarn BR, for the CKD Prognosis Consortium. Do the
associations of eGFR and albuminuria with mortality and renal failure differ
by gender? A meta-analysis from a global consortium. British Medical Journal 2013;
346:f324.
|
276)
Amin Al Olama A, . . , Eeles RA. A meta-analysis of
genome-wide association studies to identify prostate cancer susceptibility
loci associated with aggressive and non-aggressive disease. Human Molecular
Genetics 2013; 22: 408-415.
|
277)
Schöttker B, Herder C, Rothenbacher D, Roden M, Kolb
H, Müller H, Brenner H. Proinflammatory cytokines, adiponectin and increased
risk of primary cardiovascular events in patients with diabetes and renal
dysfunction: results from the ESTHER study. Diabetes Care 2013; 36:
1703-1711.
|
278)
Garcia-Closas M, ... , Kraft P. Genome-wide
association studies identify four ER-negative specific breast cancer risk
loci. Nature Genetics 2013; 45: 392-398.
|
279)
Schöttker B, Müller H, Rothenbacher D, Brenner H.
Fasting plasma glucose and HbA1c in cardiovascular risk prediction: a
sex-specific comparison in individuals without diabetes mellitus.
Diabetologia 2013; 56: 92-100.
|
280)
Gellert C, Schöttker B, Holleczek B, Stegmaier C,
Müller H, Brenner H. Using rate advancement periods for communicating the
benefits of quitting to older smokers. Tobacco Control 2013; 22: 227-230.
|
281)
Perna L, Felix J, Breitling LP, Haug U, Raum E,
Burwinkel B, Schöttker B, Brenner H. Genetic variations in the vitamin D
binding protein and season specific serum levels of 25-hydroxyvitamin D among
older adults. Epidemiology 2013; 24: 104-109.
|
|
2012
|
282)
Breitling LP, Perna L, Müller H, Raum E, Kliegel M,
Brenner H. Vitamin D and cognitive functioning in the elderly population in
Germany. Experimental Gerontology 2012; 47: 122-127.
|
283)
Chuang SC, Jenab M, Heck JE, Bosetti C, Talamini R,
Matsuo K, Castellsague X, Franceschi S, Herrero R, Winn DM, Vecchia CL,
Morgenstern H, Zhang ZF, Levi F, Maso LD, Kelsey K, McClean MD, Vaughan T,
Lazarus P,
|
284)
Muscat J, ... , Hashibe M. Diet and the risk of head
and neck cancer: a pooled analysis in the INHANCE consortium. Cancer Causes
and Control 2012; 23: 69-88.
|
285)
Schöttker B, Adamu MA, Weck MN, Müller H, Brenner H.
Helicobacter pylori infection, chronic atrophic gastritis and major cardiovascular
events: a population-based cohort study. Atherosclerosis 2012; 220: 569-574.
|
286)
Maatouk I, Wild B, Wesche D, Herzog W, Raum E,
Müller H, Rothenbacher D, Stegmaier C, Schellberg D, Brenner H. Temporal
predictors of health-related quality of life in elderly people with diabetes:
results of a German cohort study. PLoS One 2012; 7: e31088.
|
287)
Stott-Miller M, ... , Schwartz SM. History of diabetes and risk of
head and neck cancer:a pooled analysis from the International Head and Neck
Cancer Epidemiology (INHANCE) Consortium. Cancer Epidemiology Biomarkers
& Prevention 2012; 21: 294-304.
|
288)
Frank B, Weck MN, Müller H, Klopp N, Illig T, Raum
E, Brenner H. Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not
associated with the risk of chronic atrophic gastritis. European Journal of
Cancer 2012; 48: 114-120.
|
289)
Ghoussaini M, Fletcher O, ... , Easton DF.
Genome-wide association analysis identifies three new breast cancer
susceptibility loci. Nature Genetics 2012; 44: 312-318.
|
290)
Schöttker B, Herder C, Müller H, Brenner H,
Rothenbacher D. RE: Original Article - Clinical utility of creatinine and
cystatin C based definition of renal function for risk prediction of primary
cardiovascular events in patients with diabetes. Diabetes Care 2012; 35:
879-886.
|
291)
Wild B, Herzog W, Schellberg D, Lechner S, Niehoff
D, Brenner H, Rothenbacher D, Stegmaier C, Raum E. Association between the
prevalence of depression and age in a large representative German sample of
people aged 53 to 80. International Journal of Geriatric Psychiatry 2012; 27:
375-381.
|
292)
Wild B, Herzog W, Lechner S, Niehoff D, Brenner H,
Müller H, Rothenbacher D, Stegmaier C, Raum E. Gender Specific Temporal and
Cross-Sectional Associations between BMI-class and Symptoms of Depression in
the Elderly. Journal of Psychosomatic Research 2012; 72: 376-382.
|
293)
Stevens KN... , Couch FJ. 19p13. 1 is a triple
negative-specific breast cancer susceptibility locus. Cancer Research 2012;
72: 1795-1803.
|
294)
Schöttker B, Adamu M, Weck MN, Brenner H.
Helicobacter pylori infection is strongly associated with gastric and
duodenal ulcers in a large prospective study. Clinical Gastroenterology and
Hepatology 2012; 10: 487-493.
|
295)
Matsushita K, ... , for the Chronic Kidney Disease
Prognosis Consortium. Comparison of risk prediction using the CKD-EPI
equation and the MDRD Study equation for estimated glomerular filtration
rate. JAMA 2012; 307: 1941-1951.
|
296)
Lambrechts D, ... , Brauch H. 11q13 is a
Susceptibility Locus for Hormone Receptor Positive Breast Cancer. Human
Mutation 2012; 33: 1123-1132.
|
297)
Krämer HU, Müller H, Stegmaier C, Rothenbacher D,
Raum E, Brenner H. Type 2 diabetes mellitus and gender-specific risk for
colorectal neoplasia. European Journal of Epidemiology 2012; 27: 341-347.
|
298)
Coté ML, ... , Hung RJ. Increased risk of lung
cancer in individuals with a family history of the disease: A pooled analysis
from the International Lung Cancer Consortium. European Journal of Cancer
2012; 48: 1957-1968.
|
299)
Maatouk I, Wild B, Herzog W, Wesche D, Schellberg D,
Schöttker B, Müller H, Rothenbacher D, Stegmaier C, Brenner H. Longitudinal
predictors of health-related quality of life in middle-aged and older adults
with hypertension: results of a population based study. Journal of
Hypertension 2012; 30: 1364-1372.
|
300)
The Emerging Risk Factors Collaboration. *
C-reactive protein, fibrinogen, and cardiovascular disease prediction. New
England Journal of Medicine 2012; 367: 1310-1320. * Participating
investigators on behalf of the ESTHER Study: Brenner H (member of writing
committee), Schöttker B, Müller H, Rothenbacher D).
|
301)
Perna L, Haug U, Schöttker B, Müller H, Raum E,
Jansen EHJM, Brenner H. Public health implications of standardized
25-hydroxyvitamin D levels: a decrease in the prevalence of vitamin D
deficiency among older women in Germany. Preventive Medicine 2012; 55:
228-232.
|
302)
The Emerging Risk Factors Collaboration. * Adult height and the risk of cause-specific
death and vascular morbidity in 1 million adults. International Journal of
Epidemiology 2012; 41: 1419-1433. *Participating Investigators on behalf of
the ESTHER Study: Brenner H, Schöttker B, Müller H, Rothenbacher D.
|
303)
Warren H, ... , Dos Santos Silva I. 9q31. 2-rs865686 as a susceptibility
locus for estrogen receptor-positive breast cancer: evidence from the Breast
Cancer Association Consortium. Cancer Epidemiology, Biomarkers &
Prevention 2012; 21: 1783-1791.
|
304)
Schöttker B, Jansen EHJM, Haug U, Schomberg L,
Köhrle J, Brenner H. Standardization of misleading immunoassay based
25-hydroxyvitamin D levels with liquid chromatography tandem-mass
spectrometry in a large cohort study. PLoS One 2012; 7: e48774.
|
305)
Saum K-U, Müller H, Stegmaier C, Hauer K, Raum E,
Brenner H. Development and evaluation of a modification of the Fried frailty
criteria using population-independent cutpoints. Journal of the American
Geriatrics Society 2012; 60: 2110-2115.
|
306)
Fox CS, ... , on behalf of the CKD Prognosis
Consortium. Associations of kidney disease measures with mortality and
end-stage renal disease in individuals with and without diabetes: a meta-analysis.
Lancet 2012; 380: 1662-1673.
|
307)
Mahmoodi BK, ... , for the Chronic Kidney Disease
Prognosis Consortium. Associations of kidney disease measures with mortality
and end-stage renal disease in individuals with and without hypertension: a
meta-analysis. Lancet 2012; 380; 1649-1661.
|
308)
Breitling LP, Müller H, Stegmaier C, Kliegel M,
Brenner H. Association of prion protein with cognitive functioning in humans.
Experimental Gerontology 2012; 47: 919-924.
|
309)
Hallan SI, ... , for the Chronic Kidney Disease Prognosis
Consortium. * Age and association of kidney measures with mortality and
end-stage renal disease. JAMA 2012; 308: 2349-2360.
|
|
2011
|
310)
Adamu MA, Weck MN, Rothenbacher D, Brenner H.
Incidence and risk factors for the development of chronic atrophic gastritis:
five year follow-up of a population based cohort study. International Journal
of Cancer 2011; 128: 1652-1658.
|
311)
Wild B, Lechner S, Herzog W, Maatouk I, Raum E,
Müller H, Brenner H, Slaets J, Huyse F, Söllner W. Reliable integrative
assessment of health care needs in elderly persons - the INTERMED for the
Elderly (IM-E). Journal of Psychosomatic Research 2011; 70: 169-178.
|
312)
Yang R, Dick M, Marme F, Schneeweiss A, Langheinz A,
Hemminki K, Sutter C, Bugert P, Wappenschmidt B, Varon R, Schott S, Weber
BHF, Niederacher D, Arnold N, Meindl A, Bartram CR, Schmutzler RK, Müller H,
Arndt V, Brenner H, Sohn C, Burwinkel B. Genetic variants within miR-126 and
miR-335 are not associated with breast cancer risk. Breast Cancer Research
and Treatment 2011; 127: 549-554.
|
313)
The Emerging Risk Factors Collaboration. *Diabetes
mellitus, fasting glucose, and risk of cause-specific mortality. New England
Journal of Medicine 2011; 364: 829-841. * Authors on behalf of the ESTHER
study: Brenner H, Raum E, Müller H, Rothenbacher D.
|
314)
Breitling LP, Yang R, Korn B, Burwinkel B, Brenner
H. Tobacco smoking-related differential DNA methylation: 27k discovery and
replication. American Journal of Human Genetics 2011; 88: 450-457.
|
315)
Herder C, Schoettker B, Rothenbacher D, Roden M, Kolb
H, Müller H, Brenner H. Interleukin-6 in the prediction of primary
cardiovascular events in diabetes patients: results from the ESTHER study.
Atherosclerosis 2011; 216: 244-247.
|
316)
Kote-Jarai Z, . . , Eeles RA. Seven prostate cancer
susceptibility loci identified by a multi-stage genome-wide association
study. Nature Genetics 2011; 43: 785-791. doi: 10. 1038/ng. 882.
|
317)
Breitling LP, Müller H, Illig T, Rujescu D, Winterer
G, Dahmen N, Nitz B, Raum E, Rothenbacher D, Brenner H. Dopamine-related
genes and spontaneous smoking cessation in ever-heavy smokers.
Pharmacogenomics 2011; 12: 1099-1106.
|
318)
Nicolotti N, ... , Boccia S. Recreational physical
activity and risk of head and neck cancer: a pooled analysis within the
International Head and Neck Cancer Epidemiology (INHANCE) Consortium.
European Journal of Epidemiology 2011; 26: 619-628.
|
319)
Milne RL, ... , Easton DF. Confirmation of 5p12 as a
susceptibility locus for progesterone-receptor-positive, lower grade breast
cancer. Cancer Epidemiology, Biomarkers & Prevention 2011; 20: 2222-2231.
|
320)
Frank B, Müller H, Weck MN, Klopp N, Illig T, Raum
E, Brenner H. DNA repair gene polymorphisms and risk of chronic atrophic
gastritis: a case-control study. BMC Cancer 2011; 11: 440.
|
321)
Figueroa JD, ... , Spurdle AB. Associations of
common variants at 1p11. 2 and 14q24. 1 (RAD51L1) with breast cancer risk and
heterogeneity by tumor subtype: findings from the Breast Cancer Association
Consortium. Human Molecular Genetics 2011; 20: 4693-4706.
|
322)
Schöttker B, Raum E, Rothenbacher D, Müller H,
Brenner H. Prognostic value of haemoglobin A1c and fasting plasma glucose for
incident diabetes and implications for screening. European Journal of
Epidemiology 2011; 26: 779-787.
|
|
2010
|
323)
The Emerging Risk Factors Collaboration. *C-reactive
protein concentration and the risk of coronary heart disease, stroke and
mortality. Lancet 2010; 375: 132-140. * Authors on behalf of the ESTHER
study: Brenner H, Raum E, Müller H, Rothenbacher D.
|
324)
Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner
H. Alcohol consumption, serum gamma-glutamyltransferase and Helicobacter
pylori infection in a population-based study among 9733 older adults. Annals
of Epidemiology 2010; 20: 122-128.
|
325)
Gao L, Weck MN, Raum E, Stegmaier C, Rothenbacher D,
Brenner H. Sibship size, Helicobacter pylori infection and chronic atrophic
gastritis: a population-based study among 9444 older adults from Germany.
International Journal of Epidemiology 2010; 39: 129-134.
|
326)
Mobascher A, Rujescu D, Mittelstraß K, Giegling I,
Lamina C, Nitz B, Brenner H, Fehr C, Breitling LP, Gallinat J, Rothenbacher
D, Raum E, Müller H, Ruppert A, Hartmann AM, Möller HJ, Gal A, Gieger C,
Wichmann HE, Illig T, Dahmen N, Winterer G. Association of a variant in the
muscarinic acetylcholine receptor 2 gene (CHRM2) with nicotine addiction.
American Journal of Medical Genetics Part B - Neuropsychiatric Genetics 2010;
153B: 684-690.
|
327)
Breitling LP, Müller H, Raum E, Rothenbacher D,
Brenner H. Low-to-moderate alcohol consumption and smoking cessation rates:
retrospective analysis of 4576 elderly ever-smokers. Drug Alcohol Depend
2010; 108: 122-129.
|
328)
Triglyceride Coronary Disease Genetics Consortium
and Emerging Risk Factors Collaboration. *Triglyceride-mediated pathways and
coronary disease: collaborative analysis of 101 studies. Lancet 2010; 375:
1634-1639. * Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller
H, Rothenbacher D.
|
329)
Chronic Kidney Disease Prognosis Consortium.
*Association of estimated glomerular filtration rate and albuminuria with
all-cause and cardiovascular mortality in general population cohorts: a
collaborative meta-analysis. Lancet 2010; 375: 2073-2081. * Authors on behalf
of the ESTHER study: Rothenbacher D, Brenner H, Raum E, Koenig W.
|
330)
Zhang Q-L, Brenner H, Koenig W, Rothenbacher D.
Prognostic value of chronic kidney disease in patients with coronary heart
disease: role of estimating equations. Atherosclerosis 2010; 211: 342-347.
|
331)
The Emerging Risk Factors Collaboration. *Diabetes
mellitus, fasting blood glucose concentration, and risk of vascular disease:
a collaborative meta-analysis of 102 prospective studies. Lancet 2010; 375:
2215-2222. * Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller
H, Rothenbacher D.
|
332)
Truong T, ... , Spitz M. Replication of lung cancer
susceptibility loci at chromosome 15q25, 5p15, and 6p21: A pooled analysis
from the International Lung Cancer Consortium. Journal of the National Cancer
Institute 2010; 102: 959-971.
|
333)
Gao L, Weck MN, Rothenbacher D, Brenner H. Body mass
index, chronic atrophic gastritis and heartburn: a population-based study
among 8936 older adults from Germany. Alimentary Pharmacology &
Therapeutics 2010; 32: 296-302.
|
334)
Gao L, Weck MN, Nieters A, Brenner H.
Grb2-associated binder 1 (Gab1) genetic polymorphism, Helicobacter pylori
infection and chronic atrophic gastritis among older adults from Germany.
Molecular Carcinogenesis 2010; 49: 869-873.
|
335)
Breitling LP, Wolf M, Müller H, Raum E, Kliegel M,
Brenner H. Large-scale application of a telephone-based test of cognitive functioning
in older adults. Dementia and Geriatric Cognitive Disorders 2010; 30:
309-316.
|
336)
Thompson S, Kaptoge S, White I, Wood A, Perry P,
Danesh J and The Emerging Risk Factors Collaboration. *Statistical methods
for the time-to-event analysis of individual participant data from multiple
epidemiological studies. International Journal of Epidemiology 2010; 39:
1345-1359. * Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller
H, Rothenbacher D.
|
337)
Winterer G, ... , Rujescu D. Risk gene variants for
nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with
cognitive performance. American Journal of Medical Genetics. Part B,
Neuropsychiatric Genetics 2010; 153B: 1448-1458.
|
|
2009
|
338)
Zhang Q-L, Koenig W, Raum E, Stegmaier C, Brenner H,
Rothenbacher D. Epidemiology of chronic kidney disease: results from a
population of older adults in Germany. Preventive Medicine 2009; 48: 122-127.
|
339)
Breitling LP, Raum E, Müller H, Rothenbacher D,
Brenner H. Synergism between smoking and alcohol consumption with respect to
serum gamma-glutamyltransferase. Hepatology 2009; 49: 802-808.
|
340)
Gao L, Weck MN, Michel A, Pawlita M, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15
Helicobacter pylori proteins measured by multiple serology. Cancer Research
2009; 69: 2973-2980.
|
341)
Breitling LP, Dahmen N, Mittelstraß K, Illig T,
Rujescu D, Raum E, Winterer G, Brenner H. Smoking cessation and variations in
nicotinic acetylcholine receptor subunits a-5, a-3 and b-4 genes. Biological Psychiatry
2009; 65: 691-695.
|
342)
Müller H, Raum E, Rothenbacher D, Stegmaier C,
Brenner H. Association of diabetes and body mass index with levels of
prostate-specific antigen: Implications for correction of prostate-specific
antigen cut-off values?Cancer Epidemiology, Biomarkers & Prevention 2009;
18: 1350-1356.
|
343)
Weck MN, Gao L, Brenner H. Helicobacter pylori
infection and chronic atrophic gastritis: associations according to severity
of disease. Epidemiology 2009; 20: 569-574.
|
344)
Widschwendter M, Lichtenberg-Frate H, Hasenbrink G,
Schwarzer S, Dawnay A, Lam A, Menon U, Apostolidou S, Raum E, Stegmaier C,
Jacobs IJ, Brenner H. Serum oestrogen receptor alpha- and beta-bioactivity
are independently associated with breast cancer - a proof of principle study.
British Journal of Cancer 2009; 101: 160-165.
|
345)
The Emerging Risk Factors Collaboration. *
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke
and nonvascular mortality. Individual data analysis of 126,634 participants
from 36 prospective studies. JAMA 2009; 302: 412-423. * Authors on behalf of
the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
|
346)
Gao L, Michel A, Weck MN, Arndt V, Pawlita M,
Brenner H. Helicobacter pylori infection and gastric cancer risk: evaluation
of 15 Helicobacter pylori proteins determined by novel multiplex serology.
Cancer Research 2009; 69: 6164-6160.
|
347)
Breitling LP, Dahmen N, Illig T, Rujescu D, Nitz B,
Raum E, Winterer G, Rothenbacher D, Brenner H. Variants in COMT and
spontaneous smoking cessation: retrospective cohort analysis of 925 cessation
events. Pharmacogenetics & Genomics 2009; 19: 657-659.
|
348)
Breitling LP, Dahmen N, Mittelstraß K, Rujescu D,
Gallinat J, Fehr C, Giegling I, Lamina C, Illig T, Müller H, Raum E,
Rothenbacher D, Wichmann HE, Brenner H, Winterer G. Association of nicotinic
acetylcholine receptor subunit alpha-4 polymorphisms with nicotine dependence
in 5500 Germans. The Pharmacogenomics Journal 2009; 9: 219-224.
|
349)
Gao L, Weck MN, Nieters A, Brenner H. Association
between chronic atrophic gastritis and serum antibodies to 15 Helicobacter
pylori proteins measured by multiple serology. European Journal of Cancer;
69: 2973-2980.
|
350)
Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner
H. Alcohol consumption and chronic atrophic gastritis: population-based study
among 9444 older adults from Germany. International Journal of Cancer 2009;
125:2918-2922.
|
351)
The Emerging Risk Factors Collaboration. * Major
lipids, apolipoproteins and risk of vascular disease.
|
352)
JAMA 2009; 302: 1993-2000. * Authors on behalf of
the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
|
|
2008
|
353)
Raum E, Lietzau S, Stegmaier C, Brenner H. ,
Rothenbacher D. For the majority of patients with diabetes blood pressure and
lipid management is not in line with recommendations. Results from a large
population-based cohort in Germany. Pharmacoepidemiology and Drug Safety
2008; 17: 485-494.
|
354)
Widschwendter M, Apostolidou S, Raum E, Rothenbacher
D, Fiegl H, Menon U, Stegmaier C, Jacobs IJ, Brenner H. Epigenotyping in peripheral
blood cell DNA and breast cancer risk: a proof of principle study. PloS ONE
2008; 3: e2656.
|
355)
Müller H, Haug U, Rothenbacher D, Stegmaier C,
Brenner H. Evaluation of serum and urine MRP-14 as marker for early detection
of prostate cancer. Journal of Urology 2008; 180: 1309-1313.
|
|
2007
|
356)
Haug U, Hillebrand T, Bendzko P, Löw M, Rothenbacher
D, Stegmaier C, Brenner H. Mutant-enriched PCR and allele-specific
hybridization reaction to detect K-ras-mutations in stool DNA: High
prevalence in a large sample of older adults. Clinical Chemistry 2007; 53:
787-790.
|
357)
Wolkewitz M, Rothenbacher D, Löw M, Stegmaier C, Ziegler H, Radulescu M,
Brenner H, Diepgen TL. Lifetime prevalence of self-reported atopic diseases
in a population-based sample of elderly: results of the ESTHER-study. British
Journal of Dermatology 2007; 156: 693-697.
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358)
Haug U, Rothenbacher D, Wente MN, Seiler CM,
Stegmaier C, Brenner H. Tumor M2-PK as a stool marker for colorectal cancer:
comparative analysis in a large sample of unselected older adults versus
colorectal cancer patients. British Journal of Cancer 2007; 96: 1329-1334.
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359)
Raum E, Rothenbacher D, Ziegler H, Brenner H. Heavy
physical activity – risk or protective factor for cardiovascular disease? A
life course perspective. Annals of Epidemiology 2007; 17: 417-424.
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360)
Weck MN, Stegmaier C, Rothenbacher D, Brenner H.
Epidemiology of chronic atrophic gastritis: population based study among
9,444 older adults from Germany. Alimentary Pharmacology & Therapeutics
2007; 26: 879-887.
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361)
Brenner H, Rothenbacher D, Weck MN. Epidemiologic findings on
serologically defined chronic atrophic gastritis strongly depend on the
choice of the cutoff-value. International Journal of Cancer 2007; 121:
2782-2786.
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362)
Raum E, Rothenbacher D, Löw M, Stegmaier C, Ziegler
H, Brenner H. Changes of cardiovascular risk factors and their implications
in subsequent birth cohorts of older adults in Germany: a life course
approach. European Journal of Cardiovascular Prevention and Rehabilitation
2007; 14: 809-814.
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2006
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363)
Twardella D, Loew M, Rothenbacher D, Stegmaier C,
Ziegler H, Brenner H. The diagnosis of a smoking-related disease is a
prominent trigger for smoking cessation in a retrospective cohort study.
Journal of Clinical Epidemiology 2006; 59: 82-89.
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364)
Twardella D, Loew M, Rothenbacher D, Stegmaier C,
Ziegler H, Brenner H. The impact of body weight on smoking cessation in
German adults. Preventive Medicine 2006; 42: 109-113.
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365)
Wang H, Rothenbacher D, Löw M, Stegmaier C, Brenner H, Diepgen TL. Atopic diseases, immunoglobulin E
and risk of cancer of the prostate, breast, lung und colorectum.
International Journal of Cancer 2006; 119: 695-701.
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2004
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366)
Löw M, Stegmaier C, Ziegler H, Rothenbacher D, Brenner H.
Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und
optimierten Therapie chronischer Erkrankungen in der älteren Bevölkerung
(ESTHER-Studie). Deutsche Medizinische Wochenschrift 2004; 129: 2643-2647.
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367)
Bergk V, Gasse C, Rothenbacher D, Loew M, Brenner H,
Haefeli WE. Drug interactions in primary care: impact of a new algorithm on
risk determination. Clinical Pharmacology and Therapeutics 2004; 76: 85-96.
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