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Publikationen
2018
Adams
C, Richmond RC, Santos Ferreira DL, […], Brenner H et al. Circulating
Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT
Study. Cancer Epidemiol Biomarkers Prev. 2018 Oct 23.
doi:10.1158/1055-9965.Epi-18-0079.
Dadaev T, Saunders EJ, Newcombe PJ, […], Brenner H et al. Fine-mapping
of prostate cancer susceptibility loci in a large meta-analysis
identifies candidate causal variants. Nat Commun. 2018 Jun 11;9(1):2256. doi:10.1038/s41467-018-04109-8.
Gao
X, Brenner H, Holleczek B, Cuk K, Zhang Y, Anusruti A, Xuan Y, Xu Y,
Schöttker B. Urinary 8-isoprostane levels and occurrence of lung,
colorectal, prostate, breast and overall cancer: Results from a large,
population-based cohort study with 14 years of follow-up. Free Radic
Biol Med. 2018 Aug 1;123:20-6.
doi:10.1016/j.freeradbiomed.2018.05.065.
Gao
X, Zhang Y, Mons U, Brenner H. Leukocyte telomere length and
epigenetic-based mortality risk score: associations with all-cause
mortality among older adults. Epigenetics. 2018;13(8):846-57.
doi:10.1080/15592294.2018.1514853.
Gao
X, Zhang Y, Schöttker B, Brenner H. Vitamin D status and
epigenetic-based mortality risk score: strong independent and joint
prediction of all-cause mortality in a population-based cohort study.
Clin Epigenetics. 2018;10:84. doi:10.1186/s13148-018-0515-y.
Lophatananon
A, Stewart-Brown S, Kote-Jarai Z, […], Brenner H et al. Height,
selected genetic markers and prostate cancer risk: results from the
PRACTICAL consortium. Br J Cancer. 2018 Mar 20;118(6):e16. doi:10.1038/bjc.2018.6.
Matejcic M, Saunders EJ, Dadaev T, […], Brenner H et al. Germline
variation at 8q24 and prostate cancer risk in men of European ancestry.
Nat Commun. 2018 Nov 5;9(1):4616. doi:10.1038/s41467-018-06863-1.
Muhlack
DC, Hoppe LK, Stock C, Haefeli WE, Brenner H, Schöttker B. The
associations of geriatric syndromes and other patient characteristics
with the current and future use of potentially inappropriate
medications in a large cohort study. Eur J Clin Pharmacol. 2018 Dec;74(12):1633-44. doi:10.1007/s00228-018-2534-1.
Nabers
A, Perna L, Lange J, Mons U, Schartner J, Guldenhaupt J, Saum KU,
Janelidze S, Holleczek B, Rujescu D, Hansson O, Gerwert K, Brenner H.
Amyloid blood biomarker detects Alzheimer's disease. EMBO Mol Med. 2018
May;10(5). doi:10.15252/emmm.201708763.
Saunders EJ, Dadaev T, Leongamornlert DA, […], Brenner H et
al. Gene
and pathway level analyses of germline DNA-repair gene variants and
prostate cancer susceptibility using the iCOGS-genotyping array. Br J
Cancer. 2018 Mar 20;118(6):e9.
doi:10.1038/bjc.2017.468.
Schöttker
B, Muhlack DC, Hoppe LK, Holleczek B, Brenner H. Updated analysis on
polypharmacy and mortality from the ESTHER study. Eur J Clin Pharmacol. 2018 Jul;74(7):981-2.
doi:10.1007/s00228-018-2445-1.
Schumacher FR, Al Olama AA, Berndt SI, […], Brenner H et al.
Association
analyses of more than 140,000 men identify 63 new prostate cancer
susceptibility loci. Nat Genet. 2018 Jul;50(7):928-36.
doi:10.1038/s41588-018-0142-8.
Seibert TM, Fan CC, Wang Y, […], Brenner H et al. Polygenic
hazard score to guide screening for aggressive prostate cancer:
development and validation in large scale cohorts. Bmj. 2018 Jan 10;360:j5757. doi:10.1136/bmj.j5757.
Wu L, Shi W, Long J, Guo X, […], Brenner H et al. A
transcriptome-wide association study of 229,000 women identifies new
candidate susceptibility genes for breast cancer. Nat Genet. 2018 Jul;50(7):968-78. doi:10.1038/s41588-018-0132-x.
Xuan
Y, Bobak M, Anusruti A, Jansen E, Pajak A, Tamosiunas A, Saum KU,
Holleczek B, Gao X, Brenner H, Schöttker B. Association of serum
markers of oxidative stress with myocardial infarction and stroke:
pooled results from four large European cohort studies. Eur J
Epidemiol. 2018 Nov 7. doi:10.1007/s10654-018-0457-x.
Xuan
Y, Gao X, Holleczek B, Brenner H, Schöttker
B. Prediction of myocardial infarction, stroke and cardiovascular
mortality with urinary biomarkers of oxidative stress: Results from a
large cohort study. Int J Cardiol. 2018 Dec 15;273:223-9.
doi:10.1016/j.ijcard.2018.08.002.
Zhang
Y, Saum KU, Schöttker B, Holleczek B, Brenner H. Methylomic survival
predictors, frailty, and mortality. Aging (Albany NY). 2018 Mar 6;10(3):339-57. doi:10.18632/aging.101392.
2017
Taylor AE, Martin RM, Geybels MS, Stanford JL, Shui I,
..., Brenner H, .... Investigating the possible causal role of coffee
consumption with prostate cancer risk and progression using Mendelian
randomization analysis.International Journal of Cancer 2017; 140:322-328.
Brunner C, Davies NM, Martin RM, Eeles R, Easton DF,…,
Brenner H,…, Teixeira MR, Pandha H, the PRACTICAL Consortium, Zuccolo L.Alcohol
consumption and prostate cancer incidence and progression: a Mendelian randomization
study.International Journal of Cancer 2017; 140:75-85.
Jankovic N, Geelen A, Winkels RM, Mwungura B, Fedirko
V, ..., Brenner H, ....Adherence to the
WCRF/AICR dietary recommendations for cancer prevention and risk of cancer in
elderly from Europe and the United States: A Meta-Analysis within the CHANCES
project.Cancer Epidemiology, Biomarkers and Prevention 2017; 26:136-144.
Skender
S, Böhm J, Schrotz-King P, Chang-Claude J, Siegel EM, Steindorf K, Owen RW, Ose
J, Hoffmeister M, Brenner H, Ulrich CM.Plasma
25-hydroxyvitamin D3 levels in colorectal cancer patients and associations with
physical activity. Nutrition and Cancer 2017; 69:229-237.
Zhang Y, Hapala J, Brenner H, Wagner W.Individual CpG
sites that are associated with age and life expectancy become hypomethylated
upon aging.Clinical Epigenetics 2017; 9:9.
Katsoulis M, Benetou V, Karapetyan T, Feskanich D,
Grodstein F, Kymmer U, Eriksson S, Wilsgaard T, Jorgensen L, Ahmed L, Schöttker
B, Brenner H, Bellavia A, Wolk A, Kubinova R, Stegeman B, Bobak M, Boffetta P,
Trichopoulou A.Excess mortality after hip fractures in elderly from Europe and
United States: the CHANCES project.
Journal of Internal Medicine 2017; 281:300-310.
Muhlack DC, Hoppe LK, Weberpals J, Brenner H,
Schöttker B.Association of potentially inappropriate medication at older age
with cardiovascular events and overall mortality: a systematic review and
meta-analysis of cohort studies.Journal of the American Medical Directors
Association 2017; 18:211-220.
Saum KU, Schöttker B, Meid A, Holleczek B, Haefeli W,
Hauer K, Brenner H.Is polypharmacy associated with frailty in older people? Results
from the ESTHER Cohort Study.Journal of the American Geriatrics Society 2017;
65:e27-e32.
Gao X, Zhang Y, Saum KU, Schöttker B, Breitling LP, Brenner
H.Tobacco smoking and smoking-related DNA methylation are associated with the
development of frailty among older adults.Epigenetics 2017; 12:149-156.
Fehringer G, Brenner DR, Zhang ZF, Lee YCA,
Matsuo K,…, Brenner H,…, Consonni D, Olsson A, Straif K, Hung RJ. Alcohol and lung cancer risk among never smokers: a pooled analysis from
the International Lung Cancer Consortium and the SYNERGY study.International
Journal of Cancer 2017; 140:1976-1984.
Walter
V, Jansen L, Knebel P, Chang-Claude J, Hoffmeister M, Brenner H.Physical
activity and survival of colorectal cancer patients: population-based study
from Germany.International Journal of Cancer 2017; 140:1985-1997.
Hajek A, Bock J-O, Brenner H, Saum K-U,
Matschinger H, Haefeli WE, Quinzler R, Heider D, König H-H.Welche Faktoren
beeinflussen die privaten Zuzahlungen zu Gesundheitsleistungen im Alter? Ergebnisse einer Längsschnittstudie.Das Gesundheitswesen 2017; 79:e18-e25.
Berendsen
A, Kang J, van de Rest O, Jankovic N, ..., Brenner H, ....Association of
adherence to a healthy diet with cognitive decline in European and American
older adults: a meta-analysis within the CHANCES consortium.Dementia and
Geriatric Cognitive Disorders 2017; 43:215-227.
Zhang
Y, Wilson R, Heiss J, Breitling LP, Saum KU, Schöttker B, Holleczek B,
Waldenberger M, Peters A, Brenner H.DNA methylation signatures in peripheral
blood strongly predict all-cause mortality.Nature Communications 2017; 8:14617.
Zuber
V, Bettella F, Witoelar A, PRACTICAL Consortium*, CRUK GWAS, BCAC Consortium,
TRICL Consortium, Andreassen OA, Mills IG, Urbanucci A.Bromodomain protein 4
discriminates tissue-specific super-enhancers containing disease-specific
susceptibility loci in prostate and breast cancer.BMC Genomics 2017;
18:270.*Collaborator from DKFZ: Brenner H
Steele
CJ, Schöttker B, Marshall AH, Kouvonen A, O’Doherty MG, Mons U, Saum KU,
Boffetta P, Trichopoulou A, Brenner H*, Kee F*.Education achievement and type 2
diabetes – What mediates the relationship in older adults? Data from the ESTHER
study: a population-based cohort study.BMJ Open 2017; 0:e013569.*shared last
authorship
Mayer T, Meid AD, Saum KU, Brenner H, Schöttker
B, Seidling HM, Haefeli WE.
Comparison of nine instruments to calculate
anticholinergic load in a large cohort of older outpatients: association with
cognitive and functional decline, falls, and use of laxatives.American Journal
of Geriatric Psychiatry 2017; 25:531-540.
NCD
Risk Factor Collaboration (NCD-RisC)*.Worldwide trends in blood pressure from
1975 to 2015: a pooled analysis of 1,479 population-based measurement studies
with 19.1 million participants.The Lancet 2017; 389:37-55.*Collaborators on
behalf of the ESTHER study: Brenner H, Saum KU.
Ordóñez-Mena
JM, Maalmi H, Schöttker B, Saum KU, Holleczek B, Wang TJ, Burwinkel B, Brenner
H. Genetic variants in the vitamin D
pathway, 25(OH)D levels, and mortality in a large population-based cohort
study.Journal of Clinical Endocrinology & Metabolism 2017; 102:470-477.
Sluik
D, Jankovic N, Hughes M, O’Doherty MG, Schöttker B,…, Brenner H,…,.Alcoholic
beverage preference and diabetes incidence across Europe: the Consortium on
Health and Ageing Network of Cohorts in Europe and the United States (CHANCES)
project.European Journal of Clinical Nutrition 2017; 71:659-668.
Lin
HY, Chen DT, Huang PY, Liu YH, Ochoa A,…, Brenner H,…, Pandha H, Lu YJ, the
PRACTICAL consortium, Park JY.SNP interaction pattern identifier (SIPI): An
intensive search for SNP-SNP interaction patterns.Bioinformatics 2017;
33:822-833.
Freisling
H, Arnold M, Soerjomataram I, O’Doherty M, Ordóñez-Mena J, ..., Brenner H, ....Comparison
of general obesity and measures of body fat distribution in older adults in
relation to cancer risk: meta-analysis of individual participant data of seven
prospective cohorts in Europe.British Journal of Cancer 2017; 116:1486-1497.
Ben
Khedher S, Neri M, Papadopoulos A, Christiani DC, Diao N, ..., Brenner H, Saum
KU, ....Menstrual and reproductive factors and lung cancer risk: A pooled
analysis from the International Lung Cancer Consortium (ILCCO).International
Journal of Cancer 2017; 141:309-323.
Muranen
TA, Greco D, Blomqvist C, Aittomäki K, Khan S,…, Brenner H, Arndt V,…, Dennis
J, Easton DF, Schmidt MK, Nevanlinna H.Genetic modifiers of CHEK2*1100delC associated breast cancer
risk.Genetics in Medicine 2017; 19:599-603.
Shimelis
H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L,…, Arndt V,…, Brenner H,…,
Goldgar DE, Carreira A, Vreeswijk MPG, Couch FJ.BRCA2 hypomorphic missense
variants confer moderate risks of breast cancer.Cancer Research 2017;
77:2789-2799.
Schöttker
B, Saum KU, Muhlack DC, Hoppe LK, Holleczek B, Brenner H.
Polypharmacy and mortality: new insights from a large cohort of older adults by
detection of effect modification by multi-morbidity and comprehensive
correction of confounding by indication. European Journal of Clinical
Pharmacology 2017; 73:1041-1048.
Brenner
H, Jansen L, Saum KU, Holleczek B, Schöttker B.Vitamin D supplementation trials
aimed at reducing mortality have much higher power when focusing on people with
low serum 25-hydroxyvitamin D concentrations.Journal of Nutrition 2017;
147:1325-1333.
Gao
X, Gào X, Zhang Y, Breitling LP, Schöttker B, Brenner H.Associations of
self-reported smoking, cotinine levels and epigenetic smoking indicators with
oxidative stress among older adults: a population-based study.European Journal
of Epidemiology 2017; 32:443-456.
Thomas
B, Matsushita K, Abate KH, Al-Aly Z, Ärnlöv J,…, Brenner H,…, Schöttker B,…,
Vos T, Global Burden of Disease 2013 GFR Collaborators, CKD Prognosis
Consortium, Global Burden of Disease Genitourinary Expert Group.Global
cardiovascular and renal outcomes of reduced GFR.Journal of the American
Society of Nephrology 2017; 28:2167-2179.
Ordóñez-Mena
JM, Schöttker B, Saum KU, Holleczek B, Burwinkel B, Wang TJ, Brenner H.No
association of vitamin D pathway genetic variants with cancer risks in a
population-based cohort of German older adults.Cancer Epidemiology, Biomarkers
& Prevention 2017; 26:1459-1461.
Gao
X, Thomsen H, Zhang Y, Breitling LP, Brenner H.The impact of methylation
quantitative trait loci (mQTLs) on active smoking-related DNA methylation
changes.Clinical Epigenetics 2017; 9:87.
Bamia
C, Orfanos P, Juerges H, Schöttker B, Brenner H....Self-rated health and
all-cause and cause-specific mortality of older adults. Individual data
meta-analysis of prospective cohort studies participating in the CHANCES
Consortium.Maturitas 2017; 103:37-44.
Lophatananon
A, Stewart-Brown S, Kote-Jarai Z, Al Olama AA, Benlloch Garcia S, ..., Brenner
H, ....Height, selected genetic markers and prostate cancer risk: results from
the PRACTICAL consortium.British Journal of Cancer 2017; 117:734-743.
Matsushita
K, Ballew SH, Coresh J, Arima H, Ärnlöv J, ....Measures of chronic kidney
disease and risk of incident peripheral artery disease: a collaborative
meta-analysis of individual participant data.Lancet Diabetes &
Endocrinology 2017; 5:718-728.Collaborators from the ESTHER study: Brenner H,
Schöttker B, Rothenbacher D, Saum KU
Meistere
I, Werner S, Zayakin P, Siliņa K, Rulle U, Pismennaja A, Šantare D, Kikuste I,
Isajevs S, Leja M, Kupčinskas L, Kupčinskas J, Jonaitis L, Wu CY, Brenner H,
Linē A, Kalniņa Z.The prevalence of cancer-associated autoantibodies in
patients with gastric cancer and progressive grades of premalignant lesions.Cancer
Epidemiology, Biomarkers & Prevention 2017; 26:1564-1574.
Gu
F, Zhang H, Hyland PL, Berndt S, Gapstur SM, ..., Brenner H, ....Inherited
variation in circadian rhythm genes and risks of prostate cancer and three
other cancer sites in combined cancer consortia.International Journal of Cancer
2017; 141:1794-1802.
Barrdahl
M, Rudolph A, Hopper JL, Southey MC, Broeks A,…, Brenner H, Arndt V,…,
Garcia-Closas M, Easton DF, Milne RL, Chang-Claude J.Gene-environment
interactions involving functional variants: results from the Breast Cancer
Association Consortium.International Journal of Cancer 2017; 141:1830-1840.
Gao
X, Zhang Y, Brenner H.Associations of Helicobacter
pylori infection and chronic atrophic gastritis with accelerated epigenetic
ageing in older adults.British Journal of Cancer 2017; 117:1211-1214.
Boehlen
FH, Herzog W, Schellberg D, Maatouk I, Saum KU, Brenner H, Wild B.
Self-perceived coping resources of middle-aged and older adults – results of a
large population-based study.Aging and Mental Health 2017; 21:1303-1309.
Maddock
J, Zhou A, Cavadino A, Kuzma E, Bao Y,…, Brenner H, Kumari M, Power C,
Llewellyn DJ, Hyppönen E.Vitamin D and cognitive function: A mendelian
randomisation study.Scientific Reports 2017; 7:13230.
Mons
U, Müezzinler A, Schöttker B, Dieffenbach AK, Butterbach K, Schick M, Peasey A,
De Vivo I, Trichopoulou A, Boffetta P, Brenner H.Leukocyte telomere length and
all-cause, cardiovascular disease, and cancer mortality: Results from
individual participant-data meta-analysis of two large prospective cohort
studies.American Journal of Epidemiology 2017; 185:1317-1326.
Dimitrakopoulou
VI, Tsilidis KK, Haycock PC, Dimou NL, Al-Dabhani K,…, Brenner H,…, Hoffmeister
M,…, the PRACTICAL Consortium, Kraft P, Pierce BL, Schildkraut JM, on behalf of
GECCO, PRACTICAL and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI-OCAC and
TRICL-ILCCO.Circulating vitamin D concentration and risk of seven cancers:
Mendelian randomization study.The BMJ 2017; 359:j4761.
Michailidou
K, Lindström S, Dennis J, Beesley J, Hui S,…, Arndt V,…, Brenner H,…,
Chenevix-Trench G, Simard J, Kraft P, Easton DF.Association analysis identifies
65 new breast cancer risk loci.Nature 2017; 551:92-94.
Brouckaert
O, Rudolph A, Laenen A, Keeman R, Bolla MK,…, Arndt V,…, Brenner H,…,
Garcia-Closas M, Chang-Claude J, Lambrechts D, Neven P.Reproductive profiles
and risk of breast cancer subtypes: a multi-center case-only study.Breast
Cancer Research 2017; 19:119.
Milne
RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S,…, Arndt V,…, Brenner H,…,
Chenevix-Trench G, Garcia-Closas M, Schmidt MK, Antoniou AC, Simard
J.Identification of ten variants associated with risk of
estrogen-receptor-negative breast cancer.Nature Genetics 2017; 49: 1767-1778
Bock JO, Hajek A, Brenner H, Saum KU,
Matschinger H, Haefeli WE, Schöttker B, Quinzler R, Heider D, König HH.A longitudinal investigation of willingness to pay for health insurance
in Germany.Health Services Research 2017; 52:1099-1117.
Papadimitriou
N, Tsilidis KK, Orfanos P, Benetou V, Ntzani EE, ..., Brenner H, Schöttker B,
Saum KU, Holleczek B, ....Burden of hip fracture using disability-adjusted
life-years: a pooled analysis of prospective cohorts in the CHANCES consortium.Lancet
Public Health 2017; 2:e239-246.
NCD
Risk Factor Collaboration (NCD-RisC).*Worldwide trends in body-mass index,
underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of
2416 population-based measurement studies in 128.9 million children,
adolescents, and adults.The Lancet 2017; 390:2627-2642.*Collaborators on behalf
of the ESTHER study: Brenner H, Saum KU
2016
Bock
JO, König HH, Brenner H, Haefeli WE, Quinzler R, Matschinger H, Saum
KU, Schöttker B, Heider D. Associations of frailty with health care
costs - results of the ESTHER cohort study. BMC Health Serv Res. 2016
Apr 14;16(1):128. doi:
10.1186/s12913-016-1360-3.
Bock
JO, Heider D, Matschinger H, Brenner H, Saum KU, Haefeli WE, Konig HH.
Willingness to pay for health insurance among the elderly population in
Germany. Eur J Health Econ. 2016 Mar;17(2):149-58.
doi:10.1007/s10198-014-0663-8.
Boehlen
FH, Herzog W, Maatouk I, Saum KU, Brenner H, Wild B. [Treatment
preferences of elderly patients with mental disorders]. Z Gerontol
Geriatr. 2016 Feb;49(2):120-5. doi:10.1007/s00391-015-0908-x.
Bonilla
C, Lewis SJ, Martin RM, […], Brenner H et al. Pubertal development and
prostate cancer risk: Mendelian randomization study in a
population-based cohort. BMC Med. 2016 Apr 4;14:66.
doi:10.1186/s12916-016-0602-x.
Bonilla
C, Lewis SJ, Rowlands MA, […], Brenner H et al. Assessing the role of
insulin-like growth factors and binding proteins in prostate cancer
using Mendelian randomization: Genetic variants as instruments for
circulating levels. Int J Cancer. 2016 Oct 1;139(7):1520-33.
doi:10.1002/ijc.30206.
Breitling
LP, Saum KU, Perna L, Schöttker B, Holleczek B, Brenner H. Frailty is
associated with the epigenetic clock but not with telomere length in a
German cohort. Clin Epigenetics. 2016;8:21. doi:10.1186/s13148-016-0186-5.
Breitling
LP, Saum KU, Schöttker B, Holleczek B, Herth FJ, Brenner H. Pneumonia
in the Noninstitutionalized Older Population. Dtsch Arztebl Int. 2016 Sep 16;113(37):607-14.
doi:10.3238/arztebl.2016.0607.
Brück K, Stel VS, Gambaro G, […], Brenner H et al. European
CKD Burden Consortium. CKD Prevalence Varies across the European
General Population. J Am Soc Nephrol. 2016 Jul;27(7):2135-47.
doi:10.1681/asn.2015050542.
Bull
CJ, Bonilla C, Holly JM, […], Brenner H et al. Blood lipids and
prostate cancer: a Mendelian randomization analysis. Cancer Med. 2016
Jun;5(6):1125-36. doi:10.1002/cam4.695.
Chen
LS, Baker T, Hung RJ, Horton A, […], Brenner H et al. Genetic Risk Can
Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for
Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis.
EBioMedicine. 2016 Sep;11:219-26.
doi:10.1016/j.ebiom.2016.08.012.
Chen
XZ, Schöttker B, Castro FA, Chen H, Zhang Y, Holleczek B, Brenner H.
Association of helicobacter pylori infection and chronic atrophic
gastritis with risk of colonic, pancreatic and gastric cancer: A
ten-year follow-up of the ESTHER cohort study. Oncotarget. 2016 Mar 29;7(13):17182-93. doi:
10.18632/oncotarget.7946.
Fehringer
G, Kraft P, Pharoah PD, […], Brenner H et al. Cross-Cancer Genome-Wide
Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer
Reveals Novel Pleiotropic Associations. Cancer Res. 2016 Sep 1;76(17):5103-14.
doi:10.1158/0008-5472.can-15-2980.
Florath
I, Butterbach K, Heiss J, Bewerunge-Hudler M, Zhang Y, Schöttker B,
Brenner H. Type 2 diabetes and leucocyte DNA methylation: an
epigenome-wide association study in over 1,500 older adults.
Diabetologia. 2016 Jan;59(1):130-8. doi:10.1007/s00125-015-3773-7.
Fuchs
J, Scheidt-Nave C, Gaertner B, Dapp U, von Renteln-Kruse W, Saum KU,
Thorand B, Strobl R, Grill E. [Frailty in Germany: status and
perspectives : Results from a workshop of the German Society for
Epidemiology]. Z Gerontol Geriatr. 2016 Dec;49(8):734-42.
doi:10.1007/s00391-015-0999-4.
Gao
X, Mons U, Zhang Y, Breitling LP, Brenner H. DNA methylation changes in
response to active smoking exposure are associated with leukocyte
telomere length among older adults. Eur J Epidemiol. 2016 Dec;31(12):1231-41. doi:10.1007/s10654-016-0210-2.
Gao
X, Zhang Y, Breitling LP, Brenner H. Tobacco smoking and methylation of
genes related to lung cancer development. Oncotarget. 2016 Sep 13;7(37):59017-28. doi:10.18632/oncotarget.10007.
Gao
X, Zhang Y, Breitling LP, Brenner H. Relationship of tobacco smoking
and smoking-related DNA methylation with epigenetic age acceleration.
Oncotarget. 2016 Jul 26;7(30):46878-89.
doi:10.18632/oncotarget.9795.
Gusev
A, Shi H, Kichaev G, Pomerantz M, […], Brenner H et al. The PRACTICAL
Consortium. Atlas of prostate cancer heritability in European and
African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 7;7:10979.
doi:10.1038/ncomms10979.
Hajek A, Bock JO, Saum KU, Schöttker B, Brenner H, Heider D,
Konig HH. [Morbidity
Differences by Health Insurance Status in Old Age]. Gesundheitswesen.
2016 Jun 28. doi:10.1055/s-0042-108584.
Kar
SP, Beesley J, Amin Al Olama A, [...], Brenner H et al. The PRACTICAL
Consortium. Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate
Cancer Association Studies Identify Multiple New Susceptibility Loci
Shared by at Least Two Cancer Types. Cancer Discov. 2016 Sep;6(9):1052-67. doi:10.1158/2159-8290.cd-15-1227.
Khankari
NK, Murff HJ, Zeng C, […], Brenner H et al. The PRACTICAL Consortium.
Polyunsaturated fatty acids and prostate cancer risk: a Mendelian
randomisation analysis from the PRACTICAL consortium. Br J Cancer. 2016
Aug 23;115(5):624-31.
doi:10.1038/bjc.2016.228.
Lechner
S, Herzog W, Boehlen F, Maatouk I, Saum KU, Brenner H, Wild B. Control
preferences in treatment decisions among older adults - Results of a
large population-based study. J Psychosom Res. 2016 Jul;86:28-33. doi:10.1016/j.jpsychores.2016.05.004.
Maatouk
I, Herzog W, Bohlen F, Quinzler R, Lowe B, Saum KU, Brenner H, Wild B.
Association of hypertension with depression and generalized anxiety
symptoms in a large population-based sample of older adults. J Hypertens. 2016 Sep;34(9):1711-20.
doi:10.1097/hjh.0000000000001006.
Meid AD, Quinzler R, Groll A, Wild B, Saum KU, Schöttker B,
Heider D, Konig HH, Brenner H, Haefeli WE. Longitudinal
evaluation of medication underuse in older outpatients and its
association with quality of life. Eur J Clin Pharmacol. 2016 Jul;72(7):877-85. doi:10.1007/s00228-016-2047-8.
Muezzinler
A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H,
Boukamp P, Holleczek B, Stegmaier C, Brenner H. Body mass index and
leukocyte telomere length dynamics among older adults: Results from the
ESTHER cohort. Exp Gerontol. 2016 Feb;74:1-8.
doi:10.1016/j.exger.2015.11.019.
NCD
Risk Factor Collaboration (NCD-RisC).
Worldwide
trends in diabetes since 1980: a pooled analysis of 751
population-based studies with 4.4 million participants. Lancet. 2016
Apr 9;387(10027):1513-30. doi:10.1016/s0140-6736(16)00618-8.
NCD
Risk Factor Collaboration (NCD-RisC).
Trends
in adult body-mass index in 200 countries from 1975 to 2014: a pooled
analysis of 1698 population-based measurement studies with 19.2 million
participants. Lancet. 2016 Apr 2;387(10026):1377-96.
doi:10.1016/s0140-6736(16)30054-x.
NCD
Risk Factor Collaboration (NCD-RisC).
A
century of trends in adult human height. Elife. 2016 Jul 26;5. doi:10.7554/eLife.13410.
O'Doherty
MG, Cairns K, O'Neill V, Lamrock F, Jorgensen T, Brenner H, Schöttker
B, Wilsgaard T, Siganos G, Kuulasmaa K, Boffetta P, Trichopoulou A, Kee
F. Effect of major lifestyle risk factors, independent and jointly, on
life expectancy with and without cardiovascular disease: results from
the Consortium on Health and Ageing Network of Cohorts in Europe and
the United States (CHANCES). Eur J Epidemiol. 2016 May;31(5):455-68. doi:10.1007/s10654-015-0112-8.
Ordóñez-Mena
JM, Schöttker B, Mons U, […], Brenner H; Consortium on Health and
Ageing: Network of Cohorts in Europe and the United States (CHANCES).
Quantification of the smoking-associated cancer risk with rate
advancement periods: meta-analysis of individual participant data from
cohorts of the CHANCES consortium.
BMC
Med. 2016 Apr 5;14(1):62. doi: 10.1186/s12916-016-0607-5.
Ordonez-Mena
JM, Schöttker B, Fedirko V, Jenab M, Olsen A, Halkjaer J, Kampman E, de
Groot L, Jansen E, Bueno-de-Mesquita HB, Peeters PH, Siganos G,
Wilsgaard T, Perna L, Holleczek B, Pettersson-Kymmer U, Orfanos P,
Trichopoulou A, Boffetta P, Brenner H. Pre-diagnostic vitamin D
concentrations and cancer risks in older individuals: an analysis of
cohorts participating in the CHANCES consortium. Eur J Epidemiol. 2016
Mar;31(3):311-23. doi:10.1007/s10654-015-0040-7.
Perna
L, Mons U, Rujescu D, Kliegel M, Brenner H. Apolipoprotein E e4 and
Cognitive Function: A Modifiable Association Results from Two
Independent Cohort Studies. Dement Geriatr Cogn Disord. 2016;41(1-2):35-45. doi:10.1159/000440697.
Perna
L, Zhang Y, Mons U, Holleczek B, Saum KU, Brenner H. Epigenetic age
acceleration predicts cancer, cardiovascular, and all-cause mortality
in a German case cohort. Clin Epigenetics. 2016;8:64.
doi:10.1186/s13148-016-0228-z.
Schmidt MK, Hogervorst F, van Hien R, […], Brenner H et al. Age-
and Tumor Subtype-Specific Breast Cancer Risk Estimates for
CHEK2*1100delC Carriers. J Clin Oncol. 2016 Aug 10;34(23):2750-60.
doi:10.1200/jco.2016.66.5844.
Schöttker
B, Rathmann W, Herder C, Thorand B, Wilsgaard T, Njolstad I, Siganos G,
Mathiesen EB, Saum KU, Peasey A, Feskens E, Boffetta P, Trichopoulou A,
Kuulasmaa K, Kee F, Brenner H. HbA1c levels in non-diabetic older
adults - No J-shaped associations with primary cardiovascular events,
cardiovascular and all-cause mortality after adjustment for confounders
in a meta-analysis of individual participant data from six cohort
studies. BMC Med. 2016 Feb 11;14:26. doi:10.1186/s12916-016-0570-1.
Schöttker
B, Saum KU, Jansen EH, Holleczek B, Brenner H. Associations of
metabolic, inflammatory and oxidative stress markers with total
morbidity and multi-morbidity in a large cohort of older German adults.
Age Ageing. 2016 Jan;45(1):127-35.
doi:10.1093/ageing/afv159.
Shi
J, Park JH, Duan J, Berndt ST, […], Brenner H et al. Winner's Curse
Correction and Variable Thresholding Improve Performance of Polygenic
Risk Modeling Based on Genome-Wide Association Study Summary-Level
Data. PLoS Genet. 2016 Dec;12(12):e1006493.
doi:10.1371/journal.pgen.1006493.
Walter
V, Jansen L, Hoffmeister M, Ulrich A, Roth W, Blaker H, Chang-Claude J,
Brenner H. Prognostic relevance of prediagnostic weight loss and
overweight at diagnosis in patients with colorectal cancer. Am J Clin
Nutr. 2016 Oct;104(4):1110-20.
doi:10.3945/ajcn.116.136531.
Walter
V, Jansen L, Ulrich A, Roth W, Blaker H, Chang-Claude J, Hoffmeister M,
Brenner H. Alcohol consumption and survival of colorectal cancer
patients: a population-based study from Germany. Am J Clin Nutr. 2016
Jun;103(6):1497-506.
doi:10.3945/ajcn.115.127092.
Zhang
Y, Florath I, Saum KU, Brenner H. Self-reported smoking, serum
cotinine, and blood DNA methylation. Environ Res. 2016 Apr;146:395-403. doi:10.1016/j.envres.2016.01.026.
2015
Amin Al Olama A, Benlloch S, Antoniou AC, […], Brenner H et al. Risk
Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium,
Using 25 Known Prostate Cancer Susceptibility Loci. Cancer Epidemiol
Biomarkers Prev. 2015 Jul;24(7):1121-9.
doi:10.1158/1055-9965.epi-14-0317.
Amin
Al Olama A, Dadaev T, Hazelett DJ, […], Brenner H et al. Multiple novel
prostate cancer susceptibility signals identified by fine-mapping of
known risk loci among Europeans. Hum Mol Genet. 2015 Oct 1;24(19):5589-602. doi:10.1093/hmg/ddv203.
Benetou
V, Orfanos P, Feskanich D, Michaelsson K, Pettersson-Kymmer U, Ahmed
LA, Peasey A, Wolk A, Brenner H, Bobak M, Wilsgaard T, Schöttker B,
Saum KU, Bellavia A, Grodstein F, Klinaki E, Valanou E, Papatesta EM,
Boffetta P, Trichopoulou A. Education, marital status, and risk of hip
fractures in older men and women: the CHANCES project. Osteoporos Int.
2015 Jun;26(6):1733-46. doi:10.1007/s00198-015-3054-9.
Boehlen
F, Herzog W, Quinzler R, Haefeli WE, Maatouk I, Niehoff D, Saum KU,
Brenner H, Wild B. Loneliness in the elderly is associated with the use
of psychotropic drugs. Int J Geriatr Psychiatry. 2015 Sep;30(9):957-64. doi:10.1002/gps.4246.
Bozorgmehr
K, Maier W, Brenner H, Saum KU, Stock C, Miksch A, Holleczek B,
Szecsenyi J, Razum O. Social disparities in Disease Management
Programmes for coronary heart disease in Germany: a cross-classified
multilevel analysis. J Epidemiol Community Health. 2015 Nov;69(11):1091-101. doi:10.1136/jech-2014-204506.
Bozorgmehr
K, San Sebastian M, Brenner H, Razum O, Maier W, Saum KU, Holleczek B,
Miksch A, Szecsenyi J. Analysing horizontal equity in enrolment in
Disease Management Programmes for coronary heart disease in Germany
2008-2010. Int J Equity Health. 2015 Mar 10;14:28.
doi:10.1186/s12939-015-0155-1.
Cheng
TH, Thompson D, Painter J, […], Brenner H et al. Meta-analysis of
genome-wide association studies identifies common susceptibility
polymorphisms for colorectal and endometrial cancer near SH2B3 and
TSHZ1.
Sci
Rep. 2015 Dec 1;5:17369. doi:
10.1038/srep17369.
Davies NM, Gaunt TR, Lewis SJ, […], Brenner H et al. The
effects of height and BMI on prostate cancer incidence and mortality: a
Mendelian randomization study in 20,848 cases and 20,214 controls from
the PRACTICAL consortium. Cancer Causes Control. 2015 Nov;26(11):1603-16. doi:10.1007/s10552-015-0654-9.
Day
FR, Ruth KS, Thompson DJ, […], Brenner H et al. The BCAC Breast Cancer
Association Consortium. Large-scale genomic analyses link reproductive
aging to hypothalamic signaling, breast cancer susceptibility and
BRCA1-mediated DNA repair. Nat Genet. 2015 Nov;47(11):1294-303.
doi:10.1038/ng.3412.
Emrich
IE, Pickering JW, Schöttker B, Lennartz CS, Rogacev KS, Brenner H,
Rothenbacher D, Holleczek B, Saum KU, Fliser D, Heine GH. Comparison of
the performance of 2 GFR estimating equations using creatinine and
cystatin C to predict adverse outcomes in elderly individuals. Am J
Kidney Dis. 2015 Apr;65(4):636-8.
doi:10.1053/j.ajkd.2014.12.006.
Freigofas
J, Seidling HM, Quinzler R, Schöttker B, Saum KU, Brenner H, Haefeli
WE. Characteristics of medication schedules used by elderly ambulatory
patients. Eur J Clin Pharmacol. 2015 Sep;71(9):1109-20.
doi:10.1007/s00228-015-1888-x.
Laitinen
VH, Rantapero T, Fischer D, Vuorinen EM, Tammela TL, Wahlfors T,
Schleutker J. The PRACTICAL Consortium. Fine-mapping the 2q37 and
17q11.2-q22 loci for novel genes and sequence variants associated with
a genetic predisposition to prostate cancer. Int J Cancer. 2015 May 15;136(10):2316-27. doi:10.1002/ijc.29276.
Meid
AD, Quinzler R, Freigofas J, Saum KU, Schöttker B, Holleczek B, Heider
D, Konig HH, Brenner H, Haefeli WE. Medication Underuse in Aging
Outpatients with Cardiovascular Disease: Prevalence, Determinants, and
Outcomes in a Prospective Cohort Study. PLoS One. 2015;10(8):e0136339. doi:10.1371/journal.pone.0136339.
Muezzinler
A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H,
Boukamp P, Holleczek B, Stegmaier C, Brenner H. Smoking habits and
leukocyte telomere length dynamics among older adults: Results from the
ESTHER cohort. Exp Gerontol. 2015 Oct;70:18-25.
doi:10.1016/j.exger.2015.07.002.
Muezzinler
A, Mons U, Gellert C, Schöttker B, Jansen E, Kee F, O'Doherty MG,
Kuulasmaa K, Freedman ND, Abnet CC, Wolk A, Hakansson N, Orsini N,
Wilsgaard T, Bueno-de-Mesquita B, van der Schouw YT, Peeters PHM, de
Groot L, Peters A, Orfanos P, Linneberg A, Pisinger C, Tamosiunas A,
Baceviciene M, Luksiene D, Bernotiene G, Jousilahti P, Petterson-Kymmer
U, Jansson JH, Soderberg S, Eriksson S, Jankovic N, Sanchez MJ,
Veronesi G, Sans S, Drygas W, Trichopoulou A, Boffetta P, Brenner H.
Smoking and All-cause Mortality in Older Adults: Results From the
CHANCES Consortium. Am J Prev Med. 2015 Nov;49(5):e53-e63.
doi:10.1016/j.amepre.2015.04.004.
Painter
JN, O'Mara TA, Batra J, […], Brenner H et al. Fine-mapping of the HNF1B
multicancer locus identifies candidate variants that mediate
endometrial cancer risk. Hum Mol Genet. 2015 Mar 1;24(5):1478-92.
doi:10.1093/hmg/ddu552.
Perna
L, Wahl HW, Mons U, Saum KU, Holleczek B, Brenner H. Cognitive
impairment, all-cause and cause-specific mortality among non-demented
older adults. Age Ageing. 2015 May;44(3):445-51.
doi:10.1093/ageing/afu188.
Saum
KU, Dieffenbach AK, Jansen EH, Schöttker B, Holleczek B, Hauer K,
Brenner H. Association between Oxidative Stress and Frailty in an
Elderly German Population: Results from the ESTHER Cohort Study.
Gerontology. 2015;61(5):407-15. doi:10.1159/000380881.
Schöttker
B, Brenner H. Vitamin D as a Resilience Factor, Helpful for Survival of
Potentially Fatal Conditions: A Hypothesis Emerging from Recent
Findings of the ESTHER Cohort Study and the CHANCES Consortium.
Nutrients. 2015 May 6;7(5):3264-78. doi:10.3390/nu7053264.
Schöttker
B, Brenner H, Jansen EH, Gardiner J, Peasey A, Kubinova R, Pajak A,
Topor-Madry R, Tamosiunas A, Saum KU, Holleczek B, Pikhart H, Bobak M.
Evidence for the free radical/oxidative stress theory of ageing from
the CHANCES consortium: a meta-analysis of individual participant data.
BMC Med. 2015 Dec 15;13:300. doi:10.1186/s12916-015-0537-7.
Schöttker
B, Saum KU, Jansen EH, Boffetta P, Trichopoulou A, Holleczek B,
Dieffenbach AK, Brenner H. Oxidative stress markers and all-cause
mortality at older age: a population-based cohort study. J Gerontol A
Biol Sci Med Sci. 2015 Apr;70(4):518-24.
doi:10.1093/gerona/glu111.
Schöttker
B, Zhang Y, Heiss JA, Butterbach K, Jansen EH, Bewerunge-Hudler M, Saum
KU, Holleczek B, Brenner H. Discovery of a novel epigenetic cancer
marker related to the oxidative status of human blood. Genes
Chromosomes Cancer. 2015 Sep;54(9):583-94.
doi:10.1002/gcc.22271.
Stegeman
S, Amankwah E, Klein K, […], Brenner H et al. A Large-Scale Analysis of
Genetic Variants within Putative miRNA Binding Sites in Prostate
Cancer. Cancer Discov. 2015 Apr;5(4):368-79.
doi:10.1158/2159-8290.cd-14-1057.
Szulkin
R, Karlsson R, Whitington T, […], Brenner H et al. Genome-wide
association study of prostate cancer-specific survival. Cancer
Epidemiol Biomarkers Prev. 2015 Nov;24(11):1796-800.
doi:10.1158/1055-9965.epi-15-0543.
Szulkin
R, Whitington T, Eklund M, […], Brenner H et al. Prediction of
individual genetic risk to prostate cancer using a polygenic score.
Prostate. 2015 Sep;75(13):1467-74.
doi:10.1002/pros.23037.
Vart
P, Bakker SJ, Schöttker B, de Zeeuw D, Rothenbacher D, Brenner H,
Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U, Koenig W, Gansevoort
RT. Relevance of correction for drift and day-to-day variation in
cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with
independent replication in the ESTHER cohort. Clin Chem Lab Med. 2015
Aug;53(9):1381-90. doi:
10.1515/cclm-2014-0894.
Walter
V, Jansen L, Hoffmeister M, Ulrich A, Chang-Claude J, Brenner H.
Smoking and survival of colorectal cancer patients: population-based
study from Germany. Int J Cancer. 2015 Sep 15;137(6):1433-45.
doi:10.1002/ijc.29511.
Winn
DM, Lee YC, Hashibe M, Boffetta P. The INHANCE consortium: toward a
better understanding of the causes and mechanisms of head and neck
cancer. Oral Dis. 2015 Sep;21(6):685-93.
doi:10.1111/odi.12342.
Zhang
Y, Schöttker B, Ordonez-Mena J, Holleczek B, Yang R, Burwinkel B,
Butterbach K, Brenner H. F2RL3 methylation, lung cancer incidence and
mortality. Int J Cancer. 2015 Oct 1;137(7):1739-48.
doi:10.1002/ijc.29537.
2014
Agarwal D, Pineda S, Michailidou K, [...], Brenner H, Dieffenbach AK,
Arndt V, Stegmaier C et al. FGF
receptor genes and breast cancer susceptibility: results from the
Breast Cancer Association Consortium. Br J Cancer. 2014 Feb 18; 110(4):
1088–1100. Published online 2014 Feb 18. doi:
10.1038/bjc.2013.769.
Al Olama AA, Kote-Jarai Z, Berndt SI, […], Brenner H et al. A
meta-analysis of 87,040 individuals identifies 23 new susceptibility
loci for prostate cancer. Nat Genet. 2014 Oct;46(10):1103-9. doi:10.1038/ng.3094.
Bock JO, Matschinger H, Brenner H, Wild B, Haefeli WE,
Quinzler R, Saum KU, Heider D, König HH. Inequalities
in out-of-pocket payments for health care services among elderly
Germans--results of a population-based cross-sectional study. Int J
Equity Health. 2014 Jan 8;13(1):3. doi: 10.1186/1475-9276-13-3.
The
Emerging Risk Factors Collaboration*. Glycated hemoglobin measurement
and prediction of cardiovascular disease. JAMA. 2014 Mar 26;311(12):1225-33. doi:
10.1001/jama.2014.1873.
*
Authors on behalf of the ESTHER study: Brenner H.
Florath
I, Butterbach K, Muller H, Bewerunge-Hudler M, Brenner H.
Cross-sectional and longitudinal changes in DNA methylation with age:
an epigenome-wide analysis revealing over 60 novel age-associated CpG
sites. Hum Mol Genet. 2014 Mar 1;23(5):1186-201.
doi:10.1093/hmg/ddt531.
Hazelett
DJ, Rhie SK, Gaddis M, Yan C, Lakeland DL, Coetzee SG, Henderson BE,
Noushmehr H, Cozen W, Kote-Jarai Z, Eeles RA, Easton DF, Haiman CA, Lu
W, Farnham PJ, Coetzee GA. The PRACTICAL Consortium. Comprehensive
functional annotation of 77 prostate cancer risk loci. PLoS Genet. 2014 Jan;10(1):e1004102.
doi:10.1371/journal.pgen.1004102.
Heider D, Matschinger H, Müller H, Saum KU, Quinzler R,
Haefeli WE, Wild B, Lehnert T, Brenner H, König HH.
Health
care costs in the elderly in Germany: an analysis applying Andersen's
behavioral model of health care utilization. BMC Health Serv Res. 2014
Feb 14;14:71. doi:
10.1186/1472-6963-14-71.
Jansen
L, Hoffmeister M, Arndt V, Chang-Claude J, Brenner H. Stage-specific
associations between beta blocker use and prognosis after colorectal
cancer. Cancer. 2014 Apr 15;120(8):1178-86.
doi:10.1002/cncr.28546.
Koch
L, Bertram H, Eberle A, Holleczek B, Schmid-Hopfner S, Waldmann A,
Zeissig SR, Brenner H, Arndt V. Fear of recurrence in long-term breast
cancer survivors-still an issue. Results on prevalence, determinants,
and the association with quality of life and depression from the cancer
survivorship--a multi-regional population-based study. Psychooncology.
2014 May;23(5):547-54. doi:10.1002/pon.3452.
Leoncini
E, Ricciardi W, Cadoni G, […], Brenner H et al. Adult height and head
and neck cancer: a pooled analysis within the INHANCE Consortium. Eur J
Epidemiol. 2014 Jan;29(1):35-48. doi: 10.1007/s10654-013-9863-2.
Milne
RL, Herranz J, Michailidou K, […], Brenner H et al. A large-scale
assessment of two-way SNP interactions in breast cancer suceptibility
using 46.450 cases and 42.461 controls from the Breast Cancer
Association Consortium. Hum Mol Genet. 2014 Apr 1;23(7):1934-46.
doi: 10.1093/hmg/ddt581.
O'Doherty
MG, Jorgensen T, Borglykke A, Brenner H, Schöttker B, Wilsgaard T,
Siganos G, Kavousi M, Hughes M, Muezzinler A, Holleczek B, Franco OH,
Hofman A, Boffetta P, Trichopoulou A, Kee F. Repeated measures of body
mass index and C-reactive protein in relation to all-cause mortality
and cardiovascular disease: results from the consortium on health and
ageing network of cohorts in Europe and the United States (CHANCES).
Eur J Epidemiol. 2014 Dec;29(12):887-97. doi:10.1007/s10654-014-9954-8.
Pennells
L, Kaptoge S, White IR, Thompson SG, Wood AM; Emerging Risk Factors
Collaboration*. Assessing risk prediction models using individual
participant data from multiple studies. Am J Epidemiol. 2014 Mar 1;179(5):621-32. doi:
10.1093/aje/kwt298.
*
Authors on behalf of the ESTHER study: Brenner H, Schöttker B, Müller
H, Rothenbacher D.
Perna
L, Mons U, Kliegel M, Brenner H. Serum 25-hydroxyvitamin D and
cognitive decline: a longitudinal study among non-demented older
adults. Dement Geriatr Cogn Disord. 2014;38(3-4):254-63.
doi:10.1159/000362870.
Saum
KU, Dieffenbach AK, Müezzinler A, Müller H, Holleczek B, Stegmaier C,
Butterbach K, Schick M, Canzian F, Stammer H, Boukamp P, Hauer K,
Brenner H. Frailty and telomere length: Cross-sectional analysis in
3537 older adults from the ESTHER cohort. Exp Gerontol. 2014 Aug 21;58C:250-255. doi:
0.1016/j.exger.2014.08.009.
Saum
KU, Dieffenbach AK, Muller H, Holleczek B, Hauer K, Brenner H. Frailty
prevalence and 10-year survival in community-dwelling older adults:
results from the ESTHER cohort study. Eur J Epidemiol. 2014 Mar;29(3):171-9.
doi:10.1007/s10654-014-9891-6.
Saunders EJ, Dadaev T, Leongamornlert DA, […], Brenner H et
al. Fine-mapping
the HOXB region detects common variants tagging a rare coding allele:
evidence for synthetic association in prostate cancer. PLoS Genet. 2014
Feb;10(2):e1004129.
doi:10.1371/journal.pgen.1004129.
Schoeps
A, Rudolph A, Seibold P, […], Brenner H et al. Identification of new
genetic susceptibility loci for breast cancer through consideration of
gene-environment interactions. Genetic Epidemiology 2014; 38: 84-93.
Schöttker
B, Saum KU, Perna L, Ordonez-Mena JM, Holleczek B, Brenner H. Is
vitamin D deficiency a cause of increased morbidity and mortality at
older age or simply an indicator of poor health? Eur J Epidemiol. 2014
Mar;29(3):199-210. doi:10.1007/s10654-014-9894-3.
Wen
CP, Matsushita K, Coresh J, Iseki K, Islam M, Katz R, McClellan W,
Peralta CA, Wang H, de Zeeuw D, Astor BC, Gansevoort RT, Levey AS,
Levin A, and the Chronic Kidney Disease Prognosis Consortium*. Relative
risks of chronic kidney disease for mortality and end-stage renal
disease across races are similar. Kidney Int. 2014 Feb 12. doi: 10.1038/ki.2013.553.
*
Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Müller H, Schöttker B.
Wild
B, Eckl A, Herzog W, Niehoff D, Lechner S, Maatouk I, Schellberg D,
Brenner H, Muller H, Lowe B. Assessing
generalized anxiety disorder in elderly people using the GAD-7 and
GAD-2 scales: results of a validation study. Am J Geriatr Psychiatry.
2014 Oct;22(10):1029-38.
doi:10.1016/j.jagp.2013.01.076.
Wild
B, Heider D, Maatouk I, Slaets J, Konig HH, Niehoff D, Saum KU, Brenner
H, Sollner W, Herzog W. Significance and costs of complex
biopsychosocial health care needs in elderly people: results of a
population-based study. Psychosom Med. 2014 Sep;76(7):497-502.
doi:10.1097/psy.0000000000000080.
Zhang
Y, Yang R, Burwinkel B, Breitling LP, Brenner H. F2RL3 methylation as a
biomarker of current and lifetime smoking exposures. Environmental
Health Perspectives 2014; 122: 131-137.
2013
Perna L, Schöttker B, Holleczek B, Brenner H.
Serum 25-hydroxyvitamin D and incidence of fatal and non-fatal
cardiovascular events: a prospective study with repeated measurements.
Journal of Clinical Endocrinology & Metabolism 2013; 98: 4908-4915.
Perna
L, Hoffmeister M, Schöttker B, Arndt V, Haug U, Holleczek B, Burwinkel
B, Ordonez-Mena JM, Brenner H.
Vitamin D receptor polymorphism and colorectal cancer-specific and
all-cause mortality.
Cancer Epidemiology 2013; 37: 905-907.
Silbernagel
G, Schöttker B, Appelbaum S, Scharnagl H, Kleber ME, Grammer TB, Ritsch
A, Mons U, Holleczek B, Goliasch G, Niessner A, Boehm BO, Schnabel RB,
Brenner H, Blankenberg S, Landmesser U, März W.
High-density lipoprotein cholesterol, coronary artery disease and
cardiovascular mortality.
European Heart Journal 2013; 34: 3563-71.
Breitling
LP, Olsen H, Müller H, Schöttker B, Kliegel M, Brenner H.
Self- or physician-reported diabetes, glycemia markers, and cognitive
functioning in older adults in Germany.
American Journal of Geriatric Psychiatry 2013; S1064-7481(13)00282-0.
Wild B,
Eckl A, Herzog W, Niehoff D, Lechner S, Maatouk I, Schellberg D,
Brenner H, Müller H, Löwe B.
Assessing generalized anxiety disorder in elderly people by use of the
GAD-7 and GAD-2 scales - results of a validation study.
American Journal of Geriatric Psychiatry 2013; S1064-7481(13)00116-4.
Matsushita K, Ballew SH, Astor BC, de Jong PE,
Gansevoort RT, Hemmelgarn BR, Levey AS, Levin A, Wen C-P, Woodward M,
Coresh J, and for the CKD Prognosis Consortium*.
Cohort profile: the chronic kidney disease prognosis consortium.
International Journal of Epidemiology 2013; 42: 1660-1668.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Müller H,
Schöttker B.
Yin L,
Ordonez-Mena JM, Chen T, Schöttker B, Arndt V, Brenner H.
Circulating 25-hydroxyvitamin D serum concentration and total cancer
incidence and mortality: a systematic review and meta-analysis.
Preventive Medicine 2013; 57: 753-764.
Schöttker
B, Brenner H, Koenig W, Müller H, Rothenbacher D.
Prognostic association of HbA1c and fasting plasma glucose with reduced
kidney function in subjects with and without diabetes mellitus. Results
from a population-based cohort study from Germany.
Preventive Medicine 2013; 57: 596-600.
Singh GM, Danaei G, Farzadfar F, Stevens GA,
Woodward M, Wormser D, Kaptoge S, Whitlock g, Qiao Q, Lewington s, Di
Angelantonio E, van der Hoorn S, Lawes CMM, Ali MK, Mozaffarian D,
Ezzati M, Global Burdon of Metabolic Risk Factors of Chronic Diseases
Collaborating Group, Asia-Pacific Cohort Studies Collaboration (APCSC),
Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in
Europe (DECODE), Emerging risk Factor Collaboration (ERFC)*,
Prospective Studies Collaboration (PSC).
The age-specific quantitative effects of metabolic risk factors on
cardiovascular diseases and diabetes: A pooled analysis.
PloS One 2013; 8:e65174.
*Authors on behalf of the ESTHER study: Brenner H, Schöttker B, Müller
H,
Rothenbacher D.
Mons U,
Schöttker B, Müller H, Kliegel M, Brenner H.
History of lifetime smoking, smoking cessation and cognitive function
in the elderly population.
European Journal of Epidemiology 2013; 28:823-831.
Pesatori
AC, Carugno M, Consonni D, Hung RJ, Papadoupolos A, Landi M, Brenner H,
Müller H, Harris C, Duell E, Andrew A, McLaughlin J, Schwartz AG,
Wenzlaff A, Stucker I.
Hormone use and risk for lung cancer: a pooled analysis from the
International Lung Cancer Consortium (ILCCO).
British Journal of Cancer 2013; 109:1954-1964.
Yu OH,
Foulkes WD, Dastani Z, Martin RM, Eeles R, PRACTICAL Consortium*, CRUK
GWAS Investigators, Richards JB.
An assessment of the shared allelic architecture between type II
diabetes and prostate cancer.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22:1473-1475.
*Author on behalf of the ESTHER study: Brenner H.
Gellert
C, Schöttker B, Müller H, Holleczek B, Brenner H.
Impact of smoking and quitting on cardiovascular outcomes and risk
advancement periods among older adults.
European Journal of Epidemiology 2013; 28:648-658.
Shlipak MG, Matsushita K, Ärnlöv J, Inker LA,
Katz R, Polkinghorne K, Rothenbacher D, Sarnak MJ, Astor BC, Coresh J,
Levey AS, Gansevoort RT, for the CKD Prognosis Consortium.*
Cystatin C versus creatinine for determining
risk based on kidney function.
New England Journal of Medicine 2013; 369:932-943.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Schöttker B,
Koenig W.
Kote-Jarai
Z, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Dadaev T,
Jugurnauth-Little S, Ross-Adams H, Al Olama AA, Benlloch S, Halim S,
Russell R, Dunning AM, Luccarini C, Dennis J, Neal DE, Hamdy FC,
Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman
CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P,
Hunter DJ, Gapstur S, Chanock S, Berndt SI, Albanes D, Andriole G,
Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa
D, Ingles SA, John EM, Hayes RB, Pharoah P, Khaw KT, Stanford JL,
Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W,
Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park
JY, Kaneva R, Batra J, Spurdle A, Clements JA, Teixeira MR, Govindasami
K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dicks E, Baynes C, Conroy
D, Bojesen SE, Kaaks R, Vincent D, Bacot F, Tessier DC; COGS-CRUK
GWAS-ELLIPSE (Part of GAME-ON) Initiative; UK Genetic Prostate Cancer
Study Collaborators/British Association of Urological Surgeons' Section
of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium,
Easton DF, Eeles RA.
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one
of which associates with TERT expression.
Human Molecular Genetics 2013; 22: 2520-2528.
Ordóñez-Mena
JM, Schöttker B, Haug U, Müller H, Köhrle J, Schomburg L, Holleczek B,
Brenner H.
Serum 25-hydroxyvitamin D and cancer risk in older adults. Results from
a large German prospective cohort study.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 905-916.
Zhang
Y, Weck MN, Schöttker B, Rothenbacher D, Brenner H.
Gastric parietal cell antibodies, Helicobacter pylori infection, and
chronic atrophic gastritis: Evidence from a large population-based
study in Germany.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 821-826.
Shen H,
Fridley BL, Song H, Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS,
Tyrer J, Stram D, Larson MC, Köbel M; PRACTICAL Consortium, Ziogas A,
Zheng W, Yang HP, Wu AH, Wozniak EL, Woo YL, Winterhoff B, Wik E,
Whittemore AS, Wentzensen N, Weber RP, Vitonis AF, Vincent D, Vierkant
RA, Vergote I, Van Den Berg D, Van Altena AM, Tworoger SS, Thompson PJ,
Tessier DC, Terry KL, Teo SH, Templeman C, Stram DO, Southey MC, Sieh
W, Siddiqui N, Shvetsov YB, Shu XO, Shridhar V, Wang-Gohrke S, Severi
G, Schwaab I, Salvesen HB, Rzepecka IK, Runnebaum IB, Rossing MA,
Rodriguez-Rodriguez L, Risch HA, Renner SP, Poole EM, Pike MC, Phelan
CM, Pelttari LM, Pejovic T, Paul J, Orlow I, Omar SZ, Olson SH, Odunsi
K, Nickels S, Nevanlinna H, Ness RB, Narod SA, Nakanishi T, Moysich KB,
Monteiro AN, Moes-Sosnowska J, Modugno F, Menon U, McLaughlin JR,
McGuire V, Matsuo K, Adenan NA, Massuger LF, Lurie G, Lundvall L,
Lubiński J, Lissowska J, Levine DA, Leminen A, Lee AW, Le ND,
Lambrechts S, Lambrechts D, Kupryjanczyk J, Krakstad C, Konecny GE,
Kjaer SK, Kiemeney LA, Kelemen LE, Keeney GL, Karlan BY, Karevan R,
Kalli KR, Kajiyama H, Ji BT, Jensen A, Jakubowska A, Iversen E, Hosono
S, Høgdall CK, Høgdall E, Hoatlin M, Hillemanns P, Heitz F, Hein R,
Harter P, Halle MK, Hall P, Gronwald J, Gore M, Goodman MT, Giles GG,
Gentry-Maharaj A, Garcia-Closas M, Flanagan JM, Fasching PA, Ekici AB,
Edwards R, Eccles D, Easton DF, Dürst M, du Bois A, Dörk T, Doherty JA,
Despierre E, Dansonka-Mieszkowska A, Cybulski C, Cramer DW, Cook LS,
Chen X, Charbonneau B, Chang-Claude J, Campbell I, Butzow R, Bunker CH,
Brueggmann D, Brown R, Brooks-Wilson A, Brinton LA, Bogdanova N, Block
MS, Benjamin E, Beesley J, Beckmann MW, Bandera EV, Baglietto L, Bacot
F, Armasu SM, Antonenkova N, Anton-Culver H, Aben KK, Liang D, Wu X, Lu
K, Hildebrandt MA; Australian Ovarian Cancer Study Group; Australian
Cancer Study, Schildkraut JM, Sellers TA, Huntsman D, Berchuck A,
Chenevix-Trench G, Gayther SA, Pharoah PD, Laird PW, Goode EL, Pearce
CL.
Epigenetic analysis leads to identification of HNF1B as a
subtype-specific susceptibility gene for ovarian cancer.
Nature Communications 2013; 4:1628. Doi: 10.1038/ncomms2629.
* Author on behalf of the ESTHER study: Brenner H.
Eeles
RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz
M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T,
Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F,
Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L,
Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI,
Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E,
Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD,
Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB,
Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C,
Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J,
Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM,
Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M,
Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA,
Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T,
Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL,
English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R,
Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors
T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder
MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM,
Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake
B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H,
Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F,
Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent
D, Bacot F, Tessier DC; COGS–Cancer Research UK GWAS–ELLIPSE (part of
GAME-ON) Initiative; Australian Prostate Cancer Bioresource; UK Genetic
Prostate Cancer Study Collaborators/British Association of Urological
Surgeons' Section of Oncology; UK ProtecT (Prostate testing for cancer
and Treatment) Study Collaborators; PRACTICAL (Prostate Cancer
Association Group to Investigate Cancer-Associated Alterations in the
Genome) Consortium, Kote-Jarai Z, Easton DF.
Identification of 23 new prostate cancer susceptibility loci using the
iCOGS custom genotyping array.
Nature Genetics 2013; 45: 385-391.
Bojesen
SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards
SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K,
Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X,
Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S, Baynes C,
Bolla MK, Wang Q, Dennis J, McGuffog L, Barrowdale D, Lee A, Healey S,
Lush M, Tessier DC, Vincent D, Bacot F; Australian Cancer Study;
Australian Ovarian Cancer Study; Kathleen Cuningham Foundation
Consortium for Research into Familial Breast Cancer (kConFab); Gene
Environment Interaction and Breast Cancer (GENICA); Swedish Breast
Cancer Study (SWE-BRCA); Hereditary Breast and Ovarian Cancer Research
Group Netherlands (HEBON); Epidemiological study of BRCA1 & BRCA2
Mutation Carriers (EMBRACE); Genetic Modifiers of Cancer Risk in
BRCA1/2 Mutation Carriers (GEMO), Vergote I, Lambrechts S, Despierre E,
Risch HA, González-Neira A, Rossing MA, Pita G, Doherty JA, Alvarez N,
Larson MC, Fridley BL, Schoof N, Chang-Claude J, Cicek MS, Peto J,
Kalli KR, Broeks A, Armasu SM, Schmidt MK, Braaf LM, Winterhoff B,
Nevanlinna H, Konecny GE, Lambrechts D, Rogmann L, Guénel P, Teoman A,
Milne RL, Garcia JJ, Cox A, Shridhar V, Burwinkel B, Marme F, Hein R,
Sawyer EJ, Haiman CA, Wang-Gohrke S, Andrulis IL, Moysich KB, Hopper
JL, Odunsi K, Lindblom A, Giles GG, Brenner H, Simard J, Lurie G,
Fasching PA, Carney ME, Radice P, Wilkens LR, Swerdlow A, Goodman MT,
Brauch H, Garcia-Closas M, Hillemanns P, Winqvist R, Dürst M, Devilee
P, Runnebaum I, Jakubowska A, Lubinski J, Mannermaa A, Butzow R,
Bogdanova NV, Dörk T, Pelttari LM, Zheng W, Leminen A, Anton-Culver H,
Bunker CH, Kristensen V, Ness RB, Muir K, Edwards R, Meindl A, Heitz F,
Matsuo K, du Bois A, Wu AH, Harter P, Teo SH, Schwaab I, Shu XO, Blot
W, Hosono S, Kang D, Nakanishi T, Hartman M, Yatabe Y, Hamann U, Karlan
BY, Sangrajrang S, Kjaer SK, Gaborieau V, Jensen A, Eccles D, Høgdall
E, Shen CY, Brown J, Woo YL, Shah M, Azmi MA, Luben R, Omar SZ, Czene
K, Vierkant RA, Nordestgaard BG, Flyger H, Vachon C, Olson JE, Wang X,
Levine DA, Rudolph A, Weber RP, Flesch-Janys D, Iversen E, Nickels S,
Schildkraut JM, Silva Idos S, Cramer DW, Gibson L, Terry KL, Fletcher
O, Vitonis AF, van der Schoot CE, Poole EM, Hogervorst FB, Tworoger SS,
Liu J, Bandera EV, Li J, Olson SH, Humphreys K, Orlow I, Blomqvist C,
Rodriguez-Rodriguez L, Aittomäki K, Salvesen HB, Muranen TA, Wik E,
Brouwers B, Krakstad C, Wauters E, Halle MK, Wildiers H, Kiemeney LA,
Mulot C, Aben KK, Laurent-Puig P, Altena AM, Truong T, Massuger LF,
Benitez J, Pejovic T, Perez JI, Hoatlin M, Zamora MP, Cook LS,
Balasubramanian SP, Kelemen LE, Schneeweiss A, Le ND, Sohn C,
Brooks-Wilson A, Tomlinson I, Kerin MJ, Miller N, Cybulski C, Henderson
BE, Menkiszak J, Schumacher F, Wentzensen N, Le Marchand L, Yang HP,
Mulligan AM, Glendon G, Engelholm SA, Knight JA, Høgdall CK, Apicella
C, Gore M, Tsimiklis H, Song H, Southey MC, Jager A, den Ouweland AM,
Brown R, Martens JW, Flanagan JM, Kriege M, Paul J, Margolin S,
Siddiqui N, Severi G, Whittemore AS, Baglietto L, McGuire V, Stegmaier
C, Sieh W, Müller H, Arndt V, Labrèche F, Gao YT, Goldberg MS, Yang G,
Dumont M, McLaughlin JR, Hartmann A, Ekici AB, Beckmann MW, Phelan CM,
Lux MP, Permuth-Wey J, Peissel B, Sellers TA, Ficarazzi F, Barile M,
Ziogas A, Ashworth A, Gentry-Maharaj A, Jones M, Ramus SJ, Orr N, Menon
U, Pearce CL, Brüning T, Pike MC, Ko YD, Lissowska J, Figueroa J,
Kupryjanczyk J, Chanock SJ, Dansonka-Mieszkowska A, Jukkola-Vuorinen A,
Rzepecka IK, Pylkäs K, Bidzinski M, Kauppila S, Hollestelle A, Seynaeve
C, Tollenaar RA, Durda K, Jaworska K, Hartikainen JM, Kosma VM, Kataja
V, Antonenkova NN, Long J, Shrubsole M, Deming-Halverson S,
Lophatananon A, Siriwanarangsan P, Stewart-Brown S, Ditsch N, Lichtner
P, Schmutzler RK, Ito H, Iwata H, Tajima K, Tseng CC, Stram DO, van den
Berg D, Yip CH, Ikram MK, Teh YC, Cai H, Lu W, Signorello LB, Cai Q,
Noh DY, Yoo KY, Miao H, Iau PT, Teo YY, McKay J, Shapiro C, Ademuyiwa
F, Fountzilas G, Hsiung CN, Yu JC, Hou MF, Healey CS, Luccarini C,
Peock S, Stoppa-Lyonnet D, Peterlongo P, Rebbeck TR, Piedmonte M,
Singer CF, Friedman E, Thomassen M, Offit K, Hansen TV, Neuhausen SL,
Szabo CI, Blanco I, Garber J, Narod SA, Weitzel JN, Montagna M, Olah E,
Godwin AK, Yannoukakos D, Goldgar DE, Caldes T, Imyanitov EN,
Tihomirova L, Arun BK, Campbell I, Mensenkamp AR, van Asperen CJ, van
Roozendaal KE, Meijers-Heijboer H, Collée JM, Oosterwijk JC, Hooning
MJ, Rookus MA, van der Luijt RB, Os TA, Evans DG, Frost D, Fineberg E,
Barwell J, Walker L, Kennedy MJ, Platte R, Davidson R, Ellis SD, Cole
T, Bressac-de Paillerets B, Buecher B, Damiola F, Faivre L, Frenay M,
Sinilnikova OM, Caron O, Giraud S, Mazoyer S, Bonadona V,
Caux-Moncoutier V, Toloczko-Grabarek A, Gronwald J, Byrski T, Spurdle
AB, Bonanni B, Zaffaroni D, Giannini G, Bernard L, Dolcetti R,
Manoukian S, Arnold N, Engel C, Deissler H, Rhiem K, Niederacher D,
Plendl H, Sutter C, Wappenschmidt B, Borg A, Melin B, Rantala J, Soller
M, Nathanson KL, Domchek SM, Rodriguez GC, Salani R, Kaulich DG, Tea
MK, Paluch SS, Laitman Y, Skytte AB, Kruse TA, Jensen UB, Robson M,
Gerdes AM, Ejlertsen B, Foretova L, Savage SA, Lester J, Soucy P,
Kuchenbaecker KB, Olswold C, Cunningham JM, Slager S, Pankratz VS,
Dicks E, Lakhani SR, Couch FJ, Hall P, Monteiro AN, Gayther SA, Pharoah
PD, Reddel RR, Goode EL, Greene MH, Easton DF, Berchuck A, Antoniou AC,
Chenevix-Trench G, Dunning AM.
Multiple independent variants at the TERT locus are associated with
telomere length and risks of breast and ovarian cancer.
Nature Genetics 2013; 45: 371-384.
Michailidou
K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt
MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A,
Turnbull C, Rahman N; Breast and Ovarian Cancer Susceptibility
Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I,
Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A,
Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M; Hereditary Breast and
Ovarian Cancer Research Group Netherlands (HEBON), van der Luijt RB,
Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Müller-Myhsok B,
Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden
AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC,
Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini
C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H,
Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M,
Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D,
Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van
der Schoot CE, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Marme F,
Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso
MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer EJ, Tomlinson I, Kerin
MJ, Miller N, Henderson BE, Schumacher F, Le Marchand L, Andrulis IL,
Knight JA, Glendon G, Mulligan AM; kConFab Investigators; Australian
Ovarian Cancer Study Group, Lindblom A, Margolin S, Hooning MJ,
Hollestelle A, van den Ouweland AM, Jager A, Bui QM, Stone J, Dite GS,
Apicella C, Tsimiklis H, Giles GG, Severi G, Baglietto L, Fasching PA,
Haeberle L, Ekici AB, Beckmann MW, Brenner H, Müller H, Arndt V,
Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M, Figueroa J,
Lissowska J, Brinton L, Goldberg MS, Labrèche F, Dumont M, Winqvist R,
Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U, Brüning T;
GENICA (Gene Environment Interaction and Breast Cancer in Germany)
Network, Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee P,
Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J,
Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM,
Bogdanova NV, Antonenkova NN, Dörk T, Kristensen VN, Anton-Culver H,
Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo
K, Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO,
Shu XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK,
Hartman M, Miao H, Lim WY, Sng JH, Muir K, Lophatananon A,
Stewart-Brown S, Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL,
Sangrajrang S, Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB,
Cai Q, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Simard J,
Garcia-Closas M, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J,
Easton DF.
Large-scale genotyping identifies 41 new loci associated with breast
cancer risk.
Nature Genetics 2013; 45: 353-361.
French
JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S,
Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ,
Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C,
Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D, Tessier DC,
Vincent D, Bacot F, Luccarini C, Baynes C, Conroy D, Dennis J, Bolla
MK, Wang Q, Hopper JL, Southey MC, Schmidt MK, Broeks A, Verhoef S,
Cornelissen S, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan
P, Fasching PA, Loehberg CR, Ekici AB, Beckmann MW, Peto J, dos Santos
Silva I, Johnson N, Aitken Z, Sawyer EJ, Tomlinson I, Kerin MJ, Miller
N, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T,
Laurent-Puig P, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF,
Flyger H, Milne RL, Zamora MP, Arias Perez JI, Benitez J, Anton-Culver
H, Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Lichtner P,
Schmutzler RK, Engel C, Brauch H, Hamann U, Justenhoven C; GENICA
Network, Aaltonen K, Heikkilä P, Aittomäki K, Blomqvist C, Matsuo K,
Ito H, Iwata H, Sueta A, Bogdanova NV, Antonenkova NN, Dörk T, Lindblom
A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab
Investigators, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Lambrechts D,
Peeters S, Smeets A, Floris G, Chang-Claude J, Rudolph A, Nickels S,
Flesch-Janys D, Radice P, Peterlongo P, Bonanni B, Sardella D, Couch
FJ, Wang X, Pankratz VS, Lee A, Giles GG, Severi G, Baglietto L, Haiman
CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS,
Labrèche F, Dumont M, Teo SH, Yip CH, Ng CH, Vithana EN, Kristensen V,
Zheng W, Deming-Halverson S, Shrubsole M, Long J, Winqvist R, Pylkäs K,
Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Mulligan
AM, Devilee P, Seynaeve C, García-Closas M, Figueroa J, Chanock SJ,
Lissowska J, Czene K, Klevebring D, Schoof N, Hooning MJ, Martens JW,
Collée JM, Tilanus-Linthorst M, Hall P, Li J, Liu J, Humphreys K, Shu
XO, Lu W, Gao YT, Cai H, Cox A, Balasubramanian SP, Blot W, Signorello
LB, Cai Q, Pharoah PD, Healey CS, Shah M, Pooley KA, Kang D, Yoo KY,
Noh DY, Hartman M, Miao H, Sng JH, Sim X, Jakubowska A, Lubinski J,
Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, McKay J,
Toland AE, Ambrosone CB, Yannoukakos D, Godwin AK, Shen CY, Hsiung CN,
Wu PE, Chen ST, Swerdlow A, Ashworth A, Orr N, Schoemaker MJ, Ponder
BA, Nevanlinna H, Brown MA, Chenevix-Trench G, Easton DF, Dunning AM.
Functional variants at the 11q13 risk locus for breast cancer regulate
Cyclin D1 expression through long-range enhancers.
American Journal of Human Genetics 2013; 92: 489-503.
Nickels
S, Truong T, Hein R, Stevens K, Buck K, Behrens S, Eilber U, Schmidt M,
Häberle L, Vrieling A, Gaudet M, Figueroa J, Schoof N, Spurdle AB,
Rudolph A, Fasching PA, Hopper JL, Makalic E, Schmidt DF, Southey MC,
Beckmann MW, Ekici AB, Fletcher O, Gibson L, Silva Idos S, Peto J,
Humphreys MK, Wang J, Cordina-Duverger E, Menegaux F, Nordestgaard BG,
Bojesen SE, Lanng C, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA,
Brenner H, Müller H, Arndt V, Stegmaier C, Brauch H, Brüning T, Harth
V; Genica Network, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM;
kConFab; AOCS Management Group, Lambrechts D, Smeets D, Neven P,
Paridaens R, Flesch-Janys D, Obi N, Wang-Gohrke S, Couch FJ, Olson JE,
Vachon CM, Giles GG, Severi G, Baglietto L, Offit K, John EM, Miron A,
Andrulis IL, Knight JA, Glendon G, Mulligan AM, Chanock SJ, Lissowska
J, Liu J, Cox A, Cramp H, Connley D, Balasubramanian S, Dunning AM,
Shah M, Trentham-Dietz A, Newcomb P, Titus L, Egan K, Cahoon EK,
Rajaraman P, Sigurdson AJ, Doody MM, Guénel P, Pharoah PD, Schmidt MK,
Hall P, Easton DF, Garcia-Closas M, Milne RL, Chang-Claude J.
Evidence of gene-environment interactions between common breast cancer
susceptibility loci and established environmental risk factors.
PLoS Genetics 2013; 9: e1003284.
Schöttker
B, Herder C, Rothenbacher D, Perna L, Müller H, Brenner H.
Serum 25-hydroxyvitamin D levels and incident diabetes mellitus type 2.
A competing risk analysis in a large population-based cohort of older
adults.
European Journal of Epidemiology 2013; 28: 267-275.
Schöttker
B, Haug U, Schomburg L, Köhrle J, Perna L, Müller H, Holleczek B,
Brenner H.
Strong associations of 25-hydroxyvitamin D levels with all-cause,
cardiovascular, cancer and respiratory disease mortality in a large
cohort study.
The American Journal of Clinical Nutrition 2013; 97: 782-793.
Perna
L, Butterbach K, Haug U, Schöttker B, Müller H, Arndt V, Holleczek B,
Burwinkel B, Brenner H.
Vitamin D receptor genotype rs731236 (Taq1) and breast cancer prognosis.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 437-442.
Nitsch D, Grams M, Sang Y, Black C, Cirillo M,
Djurdjev O, Iseki K, Jassal SK, Kimm H, Kronenberg F, Øien CM, Levey
AS, Levin A, Woodward M, Hemmelgarn BR, for the CKD Prognosis
Consortium.*
Do the associations of eGFR and albuminuria
with mortality and renal failure differ by gender? A meta-analysis from
a global consortium.
British Medical Journal 2013; 346:f324.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Müller H,
Schöttker B.
Amin Al
Olama A, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S,
Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Hunter DJ, Henderson
BE, Thun MJ, Gaziano M, Giovannucci EL, Siddiq A, Travis RC, Cox DG,
Canzian F, Riboli E, Key TJ, Andriole G, Albanes D, Hayes RB,
Schleutker J, Auvinen A, Tammela TL, Weischer M, Stanford JL, Ostrander
EA, Cybulski C, Lubinski J, Thibodeau SN, Schaid DJ, Sorensen KD, Batra
J, Clements JA, Chambers S, Aitken J, Gardiner RA, Maier C, Vogel W,
Dörk T, Brenner H, Habuchi T, Ingles S, John EM, Dickinson JL,
Cannon-Albright L, Teixeira MR, Kaneva R, Zhang HW, Lu YJ, Park JY,
Cooney KA, Muir KR, Leongamornlert DA, Saunders E, Tymrakiewicz M,
Mahmud N, Guy M, Govindasami K, O'Brien LT, Wilkinson RA, Hall AL,
Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A, Huddart RA,
Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A, Dudderidge T,
Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL, English D,
Virtamo J, Le Marchand L, Campa D, Kaaks R, Lindstrom S, Diver WR,
Gapstur S, Yeager M, Cox A, Stern MC, Corral R, Aly M, Isaacs W,
Adolfsson J, Xu J, Zheng SL, Wahlfors T, Taari K, Kujala P, Klarskov P,
Nordestgaard BG, Røder MA, Frikke-Schmidt R, Bojesen SE, FitzGerald LM,
Kolb S, Kwon EM, Karyadi DM, Orntoft TF, Borre M, Rinckleb A, Luedeke
M, Herkommer K, Meyer A, Serth J, Marthick JR, Patterson B, Wokolorczyk
D, Spurdle A, Lose F, McDonnell SK, Joshi AD, Shahabi A, Pinto P,
Santos J, Ray A, Sellers TA, Lin HY, Stephenson RA, Teerlink C, Muller
H, Rothenbacher D, Tsuchiya N, Narita S, Cao GW, Slavov C, Mitev V; UK
Genetic Prostate Cancer Study Collaborators/British Association of
Urological Surgeons' Section of Oncology; UK ProtecT Study
Collaborators; Australian Prostate Cancer Bioresource; PRACTICAL
Consortium, Chanock S, Gronberg H, Haiman CA, Kraft P, Easton DF, Eeles
RA.
A meta-analysis of genome-wide association studies to identify prostate
cancer susceptibility loci associated with aggressive and
non-aggressive disease.
Human
Molecular Genetics 2013; 22: 408-415.
Schöttker B, Herder C, Rothenbacher D, Roden M, Kolb H,
Müller H, Brenner H.
Proinflammatory
cytokines, adiponectin and increased risk of primary cardiovascular
events in patients with diabetes and renal dysfunction: results from
the ESTHER study.
Diabetes Care 2013; 36: 1703-1711.
Garcia-Closas
M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N,
Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D,
Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK,
Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q, Dennis J,
Dicks E, Howat WJ, Schoof N, Bojesen SE, Lambrechts D, Broeks A,
Andrulis IL, Guénel P, Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher
O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A, Lindblom A,
Zheng W, Devillee P, Goldberg MS, Lubinski J, Kristensen V, Swerdlow A,
Anton-Culver H, Dörk T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu
XO, Blot W, Kang D, Hartman M, Sangrajrang S, Shen CY, Southey MC, Park
DJ, Hammet F, Stone J, Veer LJ, Rutgers EJ, Lophatananon A,
Stewart-Brown S, Siriwanarangsan P, Peto J, Schrauder MG, Ekici AB,
Beckmann MW, Dos Santos Silva I, Johnson N, Warren H, Tomlinson I,
Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Truong T,
Laurent-Puig P, Kerbrat P, Nordestgaard BG, Nielsen SF, Flyger H, Milne
RL, Perez JI, Menéndez P, Müller H, Arndt V, Stegmaier C, Lichtner P,
Lochmann M, Justenhoven C, Ko YD; Gene ENvironmental Interaction and
breast CAncer (GENICA) Network, Muranen TA, Aittomäki K, Blomqvist C,
Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y, Antonenkova NN,
Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine R; kConFab
Investigators, Tseng CC, Berg DV, Stram DO, Neven P, Dieudonné AS,
Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel
B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L,
McLean C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV,
Labrèche F, Dumont M, Yip CH, Taib NA, Cheng CY, Shrubsole M, Long J,
Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Knight JA, Glendon G,
Mulligan AM, Tollenaar RA, Seynaeve CM, Kriege M, Hooning MJ, van den
Ouweland AM, van Deurzen CH, Lu W, Gao YT, Cai H, Balasubramanian SP,
Cross SS, Reed MW, Signorello L, Cai Q, Shah M, Miao H, Chan CW, Chia
KS, Jakubowska A, Jaworska K, Durda K, Hsiung CN, Wu PE, Yu JC,
Ashworth A, Jones M, Tessier DC, González-Neira A, Pita G, Alonso MR,
Vincent D, Bacot F, Ambrosone CB, Bandera EV, John EM, Chen GK, Hu JJ,
Rodriguez-Gil JL, Bernstein L, Press MF, Ziegler RG, Millikan RM,
Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q, Tsimiklis H,
Makalic E, Schmidt D, Bui M, Gibson L, Müller-Myhsok B, Schmutzler RK,
Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto A, Liu J,
Turnbull C; Familial Breast Cancer Study (FBCS), Rahman N,
Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F; Australian Breast
Cancer Tissue Bank (ABCTB) Investigators, Olswold C, Slager S, Pilarski
R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ,
Rauh C, Lux MP, Jud SM, Bruning T, Weaver J, Sharma P, Pathak H, Tapper
W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R,
Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R,
Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg CD,
Hoover RN, Lissowska J, Figueroa JD, Chasman DI, Gaudet MM, Diver WR,
Willett WC, Hunter DJ, Simard J, Benitez J, Dunning AM, Sherman ME,
Chenevix-Trench G, Chanock SJ, Hall P, Pharoah PD, Vachon C, Easton DF,
Haiman CA, Kraft P.
Genome-wide association studies identify four ER-negative specific
breast cancer risk loci.
Nature
Genetics 2013; 45: 392-398.
Schöttker B, Müller H, Rothenbacher D, Brenner H.
Fasting plasma
glucose and HbA1c in cardiovascular risk prediction: a sex-specific
comparison in individuals without diabetes mellitus.
Diabetologia 2013; 56: 92-100.
Gellert
C, Schöttker B, Holleczek B, Stegmaier C, Müller H, Brenner H.
Using rate advancement periods for communicating the benefits of
quitting to older smokers.
Tobacco
Control 2013; 22: 227-230.
Perna L, Felix J, Breitling LP, Haug
U, Raum E, Burwinkel B, Schöttker B, Brenner H.
Genetic
variations in the vitamin D binding protein and season specific serum
levels of 25-hydroxyvitamin D among older adults.
Epidemiology 2013; 24: 104-109.
2012
Breitling LP, Perna L, Müller H, Raum E, Kliegel M, Brenner H.
Vitamin D and cognitive functioning in the elderly population in
Germany.
Experimental Gerontology 2012; 47: 122-127.
Chuang
SC, Jenab M, Heck JE, Bosetti C, Talamini R, Matsuo K, Castellsague X,
Franceschi S, Herrero R, Winn DM, Vecchia CL, Morgenstern H, Zhang ZF,
Levi F, Maso LD, Kelsey K, McClean MD, Vaughan T, Lazarus P, Muscat J,
Ramroth H, Chen C, Schwartz SM, Eluf-Neto J, Hayes RB, Purdue M, Boccia
S, Cadoni G, Zaridze D, Koifman S, Curado MP, Ahrens W, Benhamou S,
Matos E, Lagiou P, Szeszenia-Dabrowska N, Olshan AF, Fernandez L,
Menezes A, Agudo A, Daudt AW, Merletti F, Macfarlane GJ, Kjaerheim K,
Mates D, Holcatova I, Schantz S, Yu GP, Simonato L, Brenner H, Mueller
H, Conway DI, Thomson P, Fabianova E, Znaor A, Rudnai P, Healy CM,
Ferro G, Brennan P, Boffetta P, Hashibe M.
Diet and the risk of head and neck cancer: a pooled analysis in the
INHANCE consortium.
Cancer Causes and Control 2012; 23: 69-88.
Schöttker
B, Adamu MA, Weck MN, Müller H, Brenner H.
Helicobacter pylori infection, chronic atrophic gastritis and major
cardiovascular events: a population-based cohort study.
Atherosclerosis 2012; 220: 569-574.
Maatouk
I, Wild B, Wesche D, Herzog W, Raum E, Müller H, Rothenbacher D,
Stegmaier C, Schellberg D, Brenner H.
Temporal predictors of health-related quality of life in elderly people
with diabetes: results of a German cohort study.
PLoS One 2012; 7: e31088.
Stott-Miller
M, Chen C, Chuang S-C, Lee YC, Boccia S, Brenner H, Cadoni G, Dal Maso
L, La Vecchia C, Lazarus P, Levi F, Matsuo K, Morgenstern H, Muller H,
Muscat J, Olshan AF, Purdue MP, Serraino D, Vaughan TL, Zhang Z-F,
Boffetta P, Hashibe M, Schwartz SM.
History of diabetes and risk of head and neck cancer:a pooled analysis
from the International Head and Neck Cancer Epidemiology (INHANCE)
Consortium.
Cancer Epidemiology Biomarkers & Prevention 2012; 21: 294-304.
Frank
B, Weck MN, Müller H, Klopp N, Illig T, Raum E, Brenner H.
Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated
with the risk of chronic atrophic gastritis.
European Journal of Cancer 2012; 48: 114-120.
Ghoussaini
M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis
J, Wang J, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M,
Ahmed S, Driver K, Johnson N, Orr N, dos Santos Silva I, Waisfisz Q,
Meijers-Heijboer H, Uitterlinden AG, HEBON, Hall P, Czene K, Irwanto A,
Liu J,Nevanlinna H, Aittomäki K, Blomqvist C, Meindl A, Schmutzler RK,
Müller-Myhsok B, Chang-Claude J, Hein R, Nickels S, Flesch-Janys D,
Tsimiklis H, Makalic E, Schmidt D, Bui M, Hopper JJ, Apicella C, Park
DJ, Southey M, Broeks A, Verhoef S, Hogervorst FBL, Fasching PA, Sawyer
E, Tomlinson I, Kerin M, Marme F, Schneeweiss A, Sohn C, Burwinkel B,
Guénel P, Truong T, Cordina-Duverger E, Menegaux F, Bojesen SE,
Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Alonso R,
González-Neira A, Benítez J, Anton-Culver H, Ziogas A, Bernstein L,
Clarke Dur C, Brenner H, Müller H, Arndt V, Stegmaier C, FBCS,
Justenhoven C, Brauch H, Pesch B, The GENICA Network, Wang-Gohrke S,
Eilber U, Dörk T, Schürmann P, Bremer M, Hillemanns P, Bogdanova NV,
Antonenkova NN, Rogov YI, Karstens JH, Bermisheva M, Prokofieva D,
Khusnutdinova E, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma
V-M, Hartikainen J, Lambrechts D, Yesilyurt BT, Floris G, Leunen K,
Manoukian S, Bonanni B, Fortuzzi S, Peterlongo P, Radice P, Peterlongo
P, Manoukian S, Barile M, Couch FJ, Wang X, Stevens K, Lee A, Giles GG,
Baglietto L, Severi G, McLean C, Grenaker Alnæs G, Kristensen V,
Børrensen-Dale A-L, John EM, Miron A, Winqvist R, Pylkäs K,
Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Glendon G, Mulligan AM,
Devilee P, van Asperen CJ, Tollenaar RAEM, Seynaeve C, Figueroa JD,
Garcia-Closas M, Brinton L, Lissowska J, Hooning MJ, Hollestelle A,
Oldenburg RA, van den Ouweland AMW, Cox A, Reed MWR, Shah M, Jakubowska
A, Lubinski J, Jaworska K, Durda K, Jones M, Schoemaker M, Ashworth A,
Swerdlow A, Beesley J, Chen X, kConFab Investigators, Australian
Ovarian Cancer Study Group, Muir KR, Lophatananon A, Rattanamongkongul
S, Chaiwerawattana A, Kang D, Yoo K-Y, Noh D-Y, Shen C-Y, Yu J-C, Wu
P-E, Hsiung C-N, Perkins A, Swann R, Velentzis L, Eccles DM, Tapper WJ,
Gerty SM, Graham NJ, Ponder BA, Chenevix-Trench G, Pharoah PDP, Lathrop
M, Dunning AM, Rahman N, Peto J, Easton DF.
Genome-wide association analysis identifies three new breast cancer
susceptibility loci.
Nature Genetics 2012; 44: 312-318.
Schöttker
B, Herder C, Müller H, Brenner H, Rothenbacher D.
RE: Original Article - Clinical utility of creatinine and cystatin C
based definition of renal function for risk prediction of primary
cardiovascular events in patients with diabetes.
Diabetes Care 2012; 35: 879-886.
Wild B,
Herzog W, Schellberg D, Lechner S, Niehoff D, Brenner H, Rothenbacher
D, Stegmaier C, Raum E.
Association between the prevalence of depression and age in a large
representative German sample of people aged 53 to 80.
International Journal of Geriatric Psychiatry 2012; 27: 375-381.
Wild B,
Herzog W, Lechner S, Niehoff D, Brenner H, Müller H, Rothenbacher D,
Stegmaier C, Raum E.
Gender Specific Temporal and Cross-Sectional Associations between
BMI-class and Symptoms of Depression in the Elderly.
Journal of Psychosomatic Research 2012; 72: 376-382.
Stevens
KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A,
Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J,
Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, Nickels S, Brauch
H, Ko YD, Fischer HP, Network TG, Schmutzler RK, Meindl A, Bartram CR,
Schott S, Engel C, Godwin AK, Weaver J, Pathak HB, Sharma P, Brenner H,
Müller H, Arndt V, Stegmaier C, Miron P, Yannoukakos D, Stavropoulou A,
Fountzilas G, Gogas HJ, Swann R, Dwek M, Perkins KA, Milne RL, Benítez
J, Zamora MP, Ignacio Arias Pérez J, Bojesen SE, Nielsen SF,
Nordestgaard BG, Flyger H, Guénel P, Truong T, Menegaux F,
Cordina-Duverger E, Burwinkel B, Marmé F, Schneeweiss A, Sohn C, Sawyer
E, Tomlinson I, Kerin MJ, Peto J, Johnson N, Fletcher O, Dos Santos
Silva I, Fasching PA, Beckmann MW, Hartmann A, Ekici AB, Lophatananon
A, Muir K, Puttawibul P, Wiangnon S, Schmidt MK, Broeks A, Braaf LM,
Rosenberg EH, Hopper JL, Apicella C, Park DJ, Southey MC, Swerdlow AJ,
Ashworth A, Orr N, Schoemaker MJ, Anton-Culver H, Ziogas A, Bernstein
L, Clarke Dur C, Shen CY, Yu JC, Hsu HM, Hsiung CN, Hamann U, Dünnebier
T, Rüdiger T, Ulrich Ulmer H, Pharoah PD, Dunning AM, Humphreys MK,
Wang Q, Cox A, Cross SS, Reed MW, Hall P, Czene K, Ambrosone CB,
Ademuyiwa F, Hwang H, Eccles DM, Garcia-Closas M, Figueroa JD, Sherman
ME, Lissowska J, Devilee P, Seynaeve C, Tollenaar RA, Hooning MJ,
Andrulis IL, Knight JA, Glendon G, Mulligan AM, Winqvist R, Pylkäs K,
Jukkola-Vuorinen A, Grip M, John EM, Miron A, Grenaker Alnaes G,
Kristensen V, Borresen-Dale AL, Giles GG, Baglietto L, McLean CA,
Severi G, Kosel ML, Pankratz VS, Slager S, Olson JE, Radice P,
Peterlongo P, Manoukian S, Barile M, Lambrechts D, Hatse S, Dieudonne
AS, Christiaens MR, Chenevix-Trench G, Investigators K, Group A,
Beesley J, Chen X, Mannermaa A, Kosma VM, Hartikainen JM, Soini Y,
Easton DF, Couch FJ.
19p13.1 is a triple negative-specific breast cancer susceptibility
locus.
Cancer Research 2012; 72: 1795-1803.
Schöttker
B, Adamu M, Weck MN, Brenner H.
Helicobacter pylori infection is strongly associated with gastric and
duodenal ulcers in a large prospective study.
Clinical Gastroenterology and Hepatology 2012; 10: 487-493.
Matsushita
K, Mahmoodi BK, Woodward M, Emberson JR, Jafar TH, Jee SH, Polkinghorne
KR, Shankar A, Smith DH, Tonelli M, Warnock DG, Wen C-P, Coresh J,
Gansevoort RT, Hemmelgarn BR, Levey AS, for the Chronic Kidney Disease
Prognosis Consortium. (Investigators/ Collaborators for the ESTHER
study in the Chronic Kidney Disease Prognosis Consortium: Rothenbacher
D, Brenner H, Müller H, Schöttker B).
Comparison of risk prediction using the CKD-EPI equation and the MDRD
Study equation for estimated glomerular filtration rate.
JAMA 2012; 307: 1941-1951.
Lambrechts
D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS,
Apicella C , Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien
R, Sawyer E, Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez
JIA, Benítez J, Hamann U, Ko YD, Brüning T, The GENICA Network,
Chang-Claude J, Eilber U, Hein R, Nickels S, Flesch-Janys D,
Wang-Gohrke S, John EM, Miron A, Winqvist R, Pylkäs K, Jukkola-Vuorinen
A, Grip M, Chenevix-Trench G, Beesley J, Chen X, kConFab Investigators,
Australian Ovarian Cancer Study Group, Menegaux F, Cordina-Duverger E,
Shen C-Y, Yu J-C, Wu P-E, Hou M-F, Andrulis IL, Selander T, Glendon G,
Mulligan AM, Anton-Culver H, Ziogas A, Muir KR, Lophatananon A,
Rattanamongkongul S, Puttawibul P, Jones M, Orr N, Ashworth A, Swerdlow
A, Severi G, Baglietto L, Giles G, Southey M, Marmé F, Schneeweiss A,
Sohn C, Burwinkel B, Yesilyurt BT, Neven P, Paridaens R, Wildiers H,
Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Schott S, Bartram
CR, Schmutzler RK, Cox A, Brock IW, Elliott G, Cross SS, Fasching PA,
Schulz-Wendtland R, Ekici AB, Beckmann MW, Fletcher O, Johnson N, dos
Santos Silva I, Peto J, Nevanlinna H, Muranen TA, Aittomäki K,
Blomqvist C, Dörk T, Schürmann P, Bremer M, Hillemanns P, Bogdanova NV,
Antonenkova NN, Rogov YI, Karstens JH, Khusnutdinova E, Bermisheva M,
Prokofieva D, Gancev S, Jakubowska A, Lubinski J, Jaworska K, Durda K,
Nordestgaard BG, Bojesen SE, Lanng C, Mannermaa A, Kataja V, Kosma V-M,
Hartikainen JM, Radice P, Peterlongo P, Manoukian S, Bernard L, Couch
FJ, Olson JE, Wang X, Fredericksen Z, Grenaker Alnæs G, Kristensen V,
Børresen-Dale A-L, Devilee P, Tollenaar RAEM, Seynaeve CM, Hooning MJ,
García-Closas M, Chanock SJ, Lissowska J, Sherman ME, Hall P, Liu J,
Czene K, Kang D, Yoo K-Y, Noh D-Y, Lindblom A, Margolin S, Dunning AM,
Pharoah PDP, Easton DF, Guénel P, Brauch H.
11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast
Cancer.
Human Mutation 2012; 33: 1123-1132.
Krämer
HU, Müller H, Stegmaier C, Rothenbacher D, Raum E, Brenner H.
Type 2 diabetes mellitus and gender-specific risk for colorectal
neoplasia.
European Journal of Epidemiology 2012; 27: 341-347.
Coté
ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR,
Muscat JE, Rennert G, Aben KK, Andrew AS, Bencko V, Bickeböller H,
Boffetta P, Brennan P, Brenner H, Duell EJ, Fabianova E, Field JK,
Foretova L, Friis S, Harris CC, Holcatova I, Hong YC, Isla D, Janout V,
Kiemeney LA, Kiyohara C, Lan Q, Lazarus P, Lissowska J, Le Marchand L,
Mates D, Matsuo K, Mayordomo JI, McLaughlin JR, Morgenstern H, Müller
H, Orlow I, Park BJ, Pinchev M, Raji OY, Rennert HS, Rudnai P, Seow A,
Stucker I, Szeszenia-Dabrowska N, Dawn Teare M, Tjønneland A, Ugolini
D, van der Heijden HF, Wichmann E, Wiencke JK, Woll PJ, Yang P, Zaridze
D, Zhang ZF, Etzel CJ, Hung RJ.
Increased risk of lung cancer in individuals with a family history of
the disease: A pooled analysis from the International Lung Cancer
Consortium.
European Journal of Cancer 2012; 48: 1957-1968.
Maatouk
I, Wild B, Herzog W, Wesche D, Schellberg D, Schöttker B, Müller H,
Rothenbacher D, Stegmaier C, Brenner H.
Longitudinal predictors of health-related quality of life in
middle-aged and older adults with hypertension: results of a population
based study.
Journal of Hypertension 2012; 30: 1364-1372.
The Emerging Risk Factors Collaboration.*
C-reactive protein, fibrinogen, and
cardiovascular disease prediction.
New England Journal of Medicine 2012; 367: 1310-1320.
* Participating investigators on behalf of the ESTHER Study: Brenner H
(member of writing committee), Schöttker B, Müller H, Rothenbacher D).
Perna
L, Haug U, Schöttker B, Müller H, Raum E, Jansen EHJM, Brenner H.
Public health implications of standardized 25-hydroxyvitamin D levels:
a decrease in the prevalence of vitamin D deficiency among older women
in Germany.
Preventive Medicine 2012; 55: 228-232.
The Emerging Risk Factors Collaboration.*
Adult height and the risk of cause-specific
death and vascular morbidity in 1 million adults. International Journal
of Epidemiology 2012; 41: 1419-1433. *Participating Investigators on
behalf of the ESTHER Study: Brenner H, Schöttker B, Müller H,
Rothenbacher D.
Warren H, Dudbridge F, Fletcher O, Orr N, Johnson N, Hopper JL,
Apicella C, Southey MC, Mahmoodi M, Schmidt MK, Broeks A, Cornelissen
S, Braaf LM, Muir K, Lophatananon A, Chaiwerawattana A, Wiangnon S,
Fasching PA, Beckmann MW, Ekici AB, Schulz-Wendtland R, Sawyer EJ,
Tomlinson I, Kerin MJ, Burwinkel B, Marme F, Schneeweiss A, Sohn C,
Guenel P, Truong T, Laurent-Puig P, Mulot C, Bojesen SE, Nielsen SF,
Flyger H, Nordestgaard BG, Milne RL, Benitez J, Ignacio Arias Perez J,
Zamora MP, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H,
Muller H, Arndt V, Langheinz A, Meindl A, Golatta M, Bartram CR,
Schmutzler RK, Brauch H, Justenhoven C, Bruning T, Chang-Claude J,
Wang-Gohrke S, Eilber U, Dork T, Schurmann P, Bremer M, Hillemanns P,
Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Bogdanova N,
Antonenkova N, Rogov Y, Bermisheva M, Prokofyeva D, Zinnatullina G,
Khusnutdinova E, Lindblom A, Margolin S, Mannermaa A, Kosma VM,
Hartikainen JM, Kataja V, Chenevix-Trench G, Beesley J, Chen X,
Lambrechts D, Smeets A, Paridaens R, Weltens C, Flesch-Janys D, Buck K,
Behrens S, Peterlongo P, Bernard L, Manoukian S, Radice P, Couch FJ,
Vachon CM, Wang X, Olsen JE, Giles GG, Baglietto L, McLean CA, Severi
G, John EM, Miron A, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M,
Andrulis IL, Knight JA, Mulligan AM, Weerasooriya N, Devilee P,
Tollenaar RA, Martens JW, Seynaeve CM, Hooning MJ, Hollestelle A, Jager
A, Tilanus-Linthorst MM, Hall P, Czene K, Jianjun L, Jingmei L, Cox A,
Cross SS, Brock IW, Reed MW, Pharoah PD, Blows FM, Dunning AM,
Ghoussaini M, Ashworth A, Swerdlow A, Jones M, Schoemaker MJ, Easton
DF, Humphreys MK, Wang Q, Peto J, Dos Santos Silva I.
9q31.2-rs865686 as a susceptibility locus for
estrogen receptor-positive breast cancer: evidence from the Breast
Cancer Association Consortium.
Cancer Epidemiology, Biomarkers &
Prevention 2012; 21: 1783-1791.
Schöttker B, Jansen EHJM, Haug U, Schomberg L, Köhrle J, Brenner H.
Standardization of misleading immunoassay
based 25-hydroxyvitamin D levels with liquid chromatography tandem-mass
spectrometry in a large cohort study.
PLoS One 2012; 7: e48774.
Saum K-U, Müller H, Stegmaier C, Hauer K, Raum E, Brenner H.
Development and evaluation of a modification
of the Fried frailty criteria using population-independent cutpoints.
Journal of the American Geriatrics Society
2012; 60: 2110-2115.
Fox CS, Matsushita K, Woodward M, Bilo HJG, Chalmers J, Lambers
Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M,
Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen C-P, Nelson RG,
on behalf of the CKD Prognosis Consortium (Investigators/Collaborators
for the ESTHER study in the Chronic Kidney Disease Prognosis
Consortium: Rothenbacher D, Brenner H, Müller H, Schöttker B).
Associations of kidney disease measures with
mortality and end-stage renal disease in individuals with and without
diabetes: a meta-analysis.
Lancet 2012; 380: 1662-1673.
Mahmoodi BK, Matsushita K, Woodward M, Blankestijn PJ, Cirillo M,
Ohkubo T, Rossing P, Sarnak MJ, Stengel B, Yamagishi K, Yamashita K,
Zhang L, Coresh J, de Jong PE, MD2; Astor BC, for the Chronic Kidney
Disease Prognosis Consortium (Investigators/Collaborators for the
ESTHER study in the Chronic Kidney Disease Prognosis Consortium:
Rothenbacher D, Brenner H, Müller H, Schöttker B).
Associations of kidney disease measures with
mortality and end-stage renal disease in individuals with and without
hypertension: a meta-analysis.
Lancet 2012; 380; 1649-1661.
Breitling LP, Müller H, Stegmaier C, Kliegel M, Brenner H.
Association of prion protein with cognitive
functioning in humans.
Experimental Gerontology 2012; 47: 919-924.
Hallan SI, Matsushita K, Sang Y, Mahmoodi BK, Black C, Ishani A,
Kleefstra N, Naimark D, Roderick P, Tonelli M, Wetzels JFM, Astor BC,
Gansevoort RT, Levin A, Wen C-P, Coresh J for the Chronic Kidney
Disease Prognosis Consortium.*
Age and association of kidney measures with mortality and end-stage
renal disease.
JAMA 2012; 308: 2349-2360.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Raum E,
Koenig W.
2011
Adamu MA, Weck MN, Rothenbacher D, Brenner H.
Incidence and risk factors for the development of chronic atrophic
gastritis: five year follow-up of a population based cohort study.
International Journal of Cancer 2011; 128: 1652-1658.
Wild B,
Lechner S, Herzog W, Maatouk I, Raum E, Müller H, Brenner H, Slaets J,
Huyse F, Söllner W.
Reliable integrative assessment of health care needs in elderly persons
- the INTERMED for the Elderly (IM-E).
Journal of Psychosomatic Research 2011; 70: 169-178.
Yang R,
Dick M, Marme F, Schneeweiss A, Langheinz A, Hemminki K, Sutter C,
Bugert P, Wappenschmidt B, Varon R, Schott S, Weber BHF, Niederacher D,
Arnold N, Meindl A, Bartram CR, Schmutzler RK, Müller H, Arndt V,
Brenner H, Sohn C, Burwinkel B.
Genetic variants within miR-126 and miR-335 are not associated with
breast cancer risk.
Breast Cancer Research and Treatment 2011; 127: 549-554.
The
Emerging Risk Factors Collaboration.*
Diabetes mellitus, fasting glucose, and risk of cause-specific
mortality.
New England Journal of Medicine 2011; 364: 829-841.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Breitling
LP, Yang R, Korn B, Burwinkel B, Brenner H.
Tobacco smoking-related differential DNA methylation: 27k discovery and
replication.
American Journal of Human Genetics 2011; 88: 450-457.
Herder C, Schoettker B, Rothenbacher D, Roden M, Kolb H,
Müller H, Brenner H.
Interleukin-6 in
the prediction of primary cardiovascular events in diabetes patients:
results from the ESTHER study.
Atherosclerosis 2011; 216: 244-247.
Kote-Jarai
Z, Al Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Canzian
F, Riboli E, Key T, Gronberg H, Hunter DJ, Kraft P, J Thun MJ, Ingles
S, Chanock S, Albanes D, Hayes RB, Neal DE, Hamdy FC, Donovan JL,
Pharoah P, Schumacher F, Henderson BE, Stanford JL, Ostrander EA,
Dalsgaard Sorensen K, Dörk T, Andriole G, Dickinson JL, Cybulski C,
Lubinski J, Spurdle A, Clements JA, Chambers S, Aitken J, Gardiner F,
Thibodeau SN, Schaid D, John EM, Maier C, Vogel W, Cooney KA, Park JY,
Cannon-Albright L, Brenner H, Habuchi T, Zhang H-W, Lu Y-J, Kaneva R,
Muir K, Benlloch S, Leongamornlert DA, Saunders EJ, Tymrakiewicz M,
Mahmud N, Guy M, O’Brien LT, Wilkinson RA, Hall AL, Sawyer EJ, Dadaev
T, Morrison J, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC,
van As N, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper CS,
Lophatonanon A, Southey MC, Hopper JL, English D, Wahlfors T, Tammela
TLJ, Klarskov P, Nordestgaard BG, Røder MA, Tybjærg-Hansen A, Bojesen
SE, Travis R, Campa D, Kaaks R, Wiklund F, Aly M, Lindstrom S, Diver
WR, Gapstur S , Stern MC, Corral R, Virtamo J, Cox A, Haiman CA, Le
Marchand L, FitzGerald L, Kolb S, Kwon EM, Karyadi DM, Falck Orntoft T,
Borre M, Meyer A, Serth J, Yeager M, Berndt SI, Marthick JR, Patterson
B, Wokolorczyk D, Batra J, Lose F, McDonnell SK , Joshi AD, Shahabi A ,
Rinckleb AE, Ray A, Sellers TA, Lin H-Y, Stephenson RA, Farnham J,
Müller H, Rothenbacher D, Tsuchiya N, Narita S, Cao G-W , Slavov C,
Mitev V, The UK Genetic Prostate Cancer Study Collaborators/British
Association of Urological Surgeons’ Section of Oncology, The UK ProtecT
Study Collaborators, The PRACTICAL Consortium,
Easton DF, Eeles RA.
Seven prostate cancer susceptibility loci identified by a multi-stage
genome-wide association study.
Nature Genetics 2011; 43: 785-791. doi:
10.1038/ng.882.
Breitling
LP, Müller H, Illig T, Rujescu D, Winterer G, Dahmen N, Nitz B, Raum E,
Rothenbacher D, Brenner H.
Dopamine-related genes and spontaneous smoking cessation in ever-heavy
smokers.
Pharmacogenomics 2011; 12: 1099-1106.
Nicolotti
N, Chuang S-C, Cadoni G, Arzani D, Petrelli L, Bosetti C, Brenner H,
Hosono S, La Vecchia C, Matsuo K, Müller H, Muscat J, Paludetti G,
Ricciardi G, Boffetta P,
Hashibe M, Boccia S.
Recreational physical activity and risk of head and neck cancer: a
pooled analysis within the International Head and Neck Cancer
Epidemiology (INHANCE) Consortium.
European Journal of Epidemiology 2011; 26: 619-628.
Milne
RL, Goode EL, Garcia-Closas M, Couch FJ, Severi G, Hein R, Fredericksen
Z, Malats N, Zamora MP, Ignacio Arias Perez J, Benítez J, Dork T,
Schurmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliott G,
Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC,
Huang CS, Hou MF, Nordestgaard BG, Bojesen SE, Lanng C, Grenaker Alnaes
G, Kristensen V, Borresen-Dale AL, Hopper JL, Dite GS, Apicella C,
Southey MC, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Sangrajrang
S, Gaborieau V, Brennan P, McKay J, Chang-Claude J, Wang-Gohrke S,
Radice P, Peterlongo P, Manoukian S, Barile M, Giles GG, Baglietto L,
John EM, Miron A, Chanock SJ, Lissowska J, Sherman ME, Figueroa JD,
Bogdanova NV, Antonenkova NN, Zalutsky IV, Rogov YI, Fasching PA, Bayer
CM, Ekici AB, Beckmann MW, Brenner H, Muller H, Arndt V, Stegmaier C,
Andrulis IL, Knight JA, Glendon G, Mulligan AM, Mannermaa A, Kataja V,
Kosma VM, Hartikainen JM, Meindl A, Heil J, Bartram CR, Schmutzler RK,
Thomas GD, Hoover RN, Fletcher O, Gibson LJ, Dos Santos Silva I, Peto
J, Nickels S, Flesch-Janys D, Anton-Culver H, Ziogas A, Sawyer E,
Tomlinson I, Kerin M, Miller N, Schmidt MK, Broeks A, Vant Veer LJ,
Tollenaar RA, Pharoah PD, Dunning AM, Pooley KA, Marmee F, Schneeweiss
A, Sohn C, Burwinkel B, Jakubowska A, Lubinski J, Jaworska K, Durda K,
Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Kraft P,
Lindström S, Chen X, Beesley J, Hamann U, Harth V, Justenhoven C,
Winqvist R, Pylkas K, Jukkola-Vuorinen A, Grip M, Hooning M,
Hollestelle A, Oldenburg RA, Tilanus-Linthorst M, Khusnutdinova E,
Bermisheva M, Prokofieva D, Farahtdinova A, Olson JE, Wang X, Humphreys
MK, Wang Q, Chenevix-Trench G, Easton DF.
Confirmation of 5p12 as a susceptibility locus for
progesterone-receptor-positive, lower grade breast cancer.
Cancer Epidemiology, Biomarkers & Prevention 2011; 20: 2222-2231.
Frank
B, Müller H, Weck MN, Klopp N, Illig T, Raum E, Brenner H.
DNA repair gene polymorphisms and risk of chronic atrophic gastritis: a
case-control study.
BMC Cancer 2011; 11: 440.
Figueroa
JD, Garcia-Closas M, Humphreys M, Platte R, Hopper JL, Southey MC,
Apicella C, Hammet F, Schmidt MK, Broeks A, Tollenaar RA, Van 't Veer
LJ, Fasching PA, Beckmann MW, Ekici AB, Strick R, Peto J, Dos Santos
Silva I, Fletcher O, Johnson N, Sawyer E, Tomlinson I, Kerin M,
Burwinkel B, Marme F, Schneeweiss A, Sohn C, Bojesen S, Flyger H,
Nordestgaard BG, Benítez J, Milne R, Arias JI, Zamora MP, Brenner H,
Müller H, Arndt V, Rahman N, Turnbull C, Seal S, Renwick A, Brauch H,
Justenhoven C, Brüningv T; The GENICA network, Chang-Claude J, Hein R,
Wang-Gohrke S, Dörk T, Schürmann P, Bremer M, Hillemanns P, Nevanlinna
H, Heikkinen T, Aittomäki K, Blomqvist C, Bogdanova N, Antonenkovav N,
Rogov Y, Karstens JH, Bermisheva M, Prokofyeva D, Gancev SH,
.Khusnutdinova E, Lindblom A, Margolin S, Chenevix-Trench G, Beesley J,
Chen X; kConFab AOCS Management Group, Mannermaa A, Kosma VM, Soini Y,
Kataja V, Lambrechts D, Yesilyurt BT, Chrisiaens MR, Peeters S, Radice
P, Peterlongo P, Manoukian S, Barile M, Couch F, Lee AM, Diasio R, Wang
X, Giles GG, Severi G, Baglietto L, Maclean C, Offit K, Robson M,
Joseph V, Gaudet M, John EM, Winqvist R, Pylkäs K, Jukkola-Vuorinen A,
Grip M, Andrulis I, Knight JA, Mulligan AM, O'Malley FP, Brinton L,
Sherman M, Lissowska J, Chanock S, Hooning M, Martens JW, van den
Ouweland AM, Collée JM, Hall P, Czene K, Cox A, Brock IW, Reed MW,
Cross SS, Pharoah P, Dunning AM, Kang D, Yoo KY, Noh DY, Ahn SH,
Jakubowska A, Lubinski J, Jaworska K, Durda K, Sangrajrang S, Gaborieau
V, .Brennan P, McKay J, Shen CY, Ding SL, Hsu HM, Yu JC, Anton-Culver
H, Ziogas A, .Ashworth A, Swerdlow A, Jones M, Orr N, Trentham-Dietz A,
Egan K, Newcomb P, Titus-.Ernstoff L, Easton D, Spurdle AB.
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with
breast cancer risk and heterogeneity by tumor subtype: findings from
the Breast Cancer Association Consortium.
Human Molecular Genetics 2011; 20: 4693-4706.
Schöttker B, Raum E, Rothenbacher D, Müller H,
Brenner H.
Prognostic value of haemoglobin A1c and fasting plasma glucose for
incident diabetes and implications for screening.
European Journal of Epidemiology 2011; 26: 779-787.
2010
The Emerging Risk Factors Collaboration.*
C-reactive protein concentration and the risk of coronary heart
disease, stroke and mortality.
Lancet 2010; 375: 132-140.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H.
Alcohol
consumption, serum gamma-glutamyltransferase and Helicobacter pylori
infection in a population-based study among 9733 older adults.
Annals of Epidemiology 2010; 20: 122-128.
Gao L,
Weck MN, Raum E, Stegmaier C, Rothenbacher D, Brenner H.
Sibship size, Helicobacter pylori infection and chronic atrophic
gastritis: a population-based study among 9444 older adults from
Germany.
International Journal of Epidemiology 2010; 39: 129-134.
Mobascher
A, Rujescu D, Mittelstraß K, Giegling I, Lamina C, Nitz B, Brenner H,
Fehr C, Breitling LP, Gallinat J, Rothenbacher D, Raum E, Müller H,
Ruppert A, Hartmann AM, Möller HJ, Gal A, Gieger C, Wichmann HE, Illig
T, Dahmen N, Winterer G.
Association of a variant in the muscarinic acetylcholine receptor 2
gene (CHRM2) with nicotine addiction.
American Journal of Medical Genetics Part B - Neuropsychiatric Genetics
2010; 153B: 684-690.
Breitling
LP, Müller H, Raum E, Rothenbacher D, Brenner H.
Low-to-moderate alcohol consumption and smoking cessation rates:
retrospective analysis of 4576 elderly ever-smokers.
Drug Alcohol Depend 2010; 108: 122-129.
Triglyceride
Coronary Disease Genetics Consortium and Emerging Risk Factors
Collaboration.*
Triglyceride-mediated pathways and coronary disease: collaborative
analysis of 101 studies.
Lancet 2010; 375: 1634-1639.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Chronic Kidney Disease Prognosis Consortium.*
Association of estimated glomerular filtration rate and albuminuria
with all-cause and cardiovascular mortality in general population
cohorts: a collaborative meta-analysis.
Lancet 2010; 375: 2073-2081.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Raum E,
Koenig W.
Zhang
Q-L, Brenner H, Koenig W, Rothenbacher D.
Prognostic value of chronic kidney disease in patients with coronary
heart disease: role of estimating equations.
Atherosclerosis 2010; 211: 342-347.
The
Emerging Risk Factors Collaboration.*
Diabetes mellitus, fasting blood glucose concentration, and risk of
vascular disease: a collaborative meta-analysis of 102 prospective
studies.
Lancet 2010; 375: 2215-2222.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Truong
T, Hung RJ, Amos CI, Wu X, Bickeboeller H, Rosenberger A, Sauter W,
Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R,
Wiencke JK, Wrensch M, Hansen H, Kelsey KT, Matsuo K, Tajima K,
Schwartz A, Wenzlaff A, Seow A, Ying C, Staratschek-Jox A, Nuernberg P,
Stoelben E, Wolf J, Lazarus P, Muscat JE, Gallagher C, Zienolddiny S,
Haugen A, van der Heijden HFM, Kiemeney LA, Isla D, Mayordomo JI,
Rafnar T, Stefansson K, Zhang ZF, Chang SC, Kim JH, Hong YC, Duell EJ,
Andrew AS, Lejbkowicz F, Rennert G, Mueller H, Brenner H, Le Marchand
L, Benhamou S, Bouchardy C, Teare MD, Xue X, McLaughlin J, Liu G, McKay
JD, Brennan P, Spitz M.
Replication of lung cancer susceptibility loci at chromosome 15q25,
5p15, and 6p21: A pooled analysis from the International Lung Cancer
Consortium.
Journal of the National Cancer Institute 2010; 102: 959-971.
Gao L,
Weck MN, Rothenbacher D, Brenner H.
Body mass index, chronic atrophic gastritis and heartburn: a
population-based study among 8936 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2010; 32: 296-302.
Gao L,
Weck MN, Nieters A, Brenner H.
Grb2-associated binder 1 (Gab1) genetic polymorphism, Helicobacter
pylori infection and chronic atrophic gastritis among older adults from
Germany.
Molecular Carcinogenesis 2010; 49: 869-873.
Breitling
LP, Wolf M, Müller H, Raum E, Kliegel M, Brenner H.
Large-scale application of a telephone-based test of cognitive
functioning in older adults.
Dementia and Geriatric Cognitive Disorders 2010; 30: 309-316.
Thompson
S, Kaptoge S, White I, Wood A, Perry P, Danesh J and The Emerging Risk
Factors Collaboration.*
Statistical methods for the time-to-event analysis of individual
participant data from multiple epidemiological studies.
International Journal of Epidemiology 2010; 39: 1345-1359.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Winterer G, Mittelstraß K, Giegling I, Lamina
C, Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat
J, Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller H-J,
Gieger C, Wichmann H-E, Illig T, Dahmen N, Rujescu D.
Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4
cluster are associated with cognitive performance.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
2010; 153B: 1448-1458.
2009
Zhang Q-L, Koenig W, Raum E, Stegmaier C, Brenner H, Rothenbacher D.
Epidemiology of chronic kidney disease: results from a population of
older adults in Germany.
Preventive Medicine 2009; 48: 122-127.
Breitling
LP, Raum E, Müller H, Rothenbacher D, Brenner H.
Synergism between smoking and alcohol consumption with respect to serum
gamma-glutamyltransferase.
Hepatology 2009; 49: 802-808.
Gao L,
Weck MN, Michel A, Pawlita M, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to
15 Helicobacter pylori proteins measured by multiple serology.
Cancer Research 2009; 69: 2973-2980.
Breitling
LP, Dahmen N, Mittelstraß K, Illig T, Rujescu D, Raum E, Winterer G,
Brenner H.
Smoking cessation and variations in nicotinic acetylcholine receptor
subunits a-5, a-3 and b-4 genes.
Biological Psychiatry 2009; 65: 691-695.
Müller
H, Raum E, Rothenbacher D, Stegmaier C, Brenner H.
Association of diabetes and body mass index with levels of
prostate-specific antigen: Implications for correction of
prostate-specific antigen cut-off values?
Cancer Epidemiology, Biomarkers & Prevention 2009; 18: 1350-1356.
Weck
MN, Gao L, Brenner H.
Helicobacter pylori infection and chronic atrophic gastritis:
associations according to severity of disease.
Epidemiology 2009; 20: 569-574.
Widschwendter
M, Lichtenberg-Frate H, Hasenbrink G, Schwarzer S, Dawnay A, Lam A,
Menon U, Apostolidou S, Raum E, Stegmaier C, Jacobs IJ, Brenner H.
Serum oestrogen receptor alpha- and beta-bioactivity are independently
associated with breast cancer - a proof of principle study.
British Journal of Cancer 2009; 101: 160-165.
The Emerging Risk Factors Collaboration.*
Lipoprotein(a) concentration and the risk of coronary
heart disease, stroke and nonvascular mortality. Individual data
analysis of 126,634 participants from 36 prospective studies. JAMA
2009; 302: 412-423.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Gao L,
Michel A, Weck MN, Arndt V, Pawlita M, Brenner H.
Helicobacter pylori infection and gastric cancer risk: evaluation of 15
Helicobacter pylori proteins determined by novel multiplex serology.
Cancer Research 2009; 69: 6164-6160.
Breitling
LP, Dahmen N, Illig T, Rujescu D, Nitz B, Raum E, Winterer G,
Rothenbacher D, Brenner H.
Variants in COMT and spontaneous smoking cessation: retrospective
cohort analysis of 925 cessation events.
Pharmacogenetics & Genomics 2009; 19: 657-659.
Breitling
LP, Dahmen N, Mittelstraß K, Rujescu D, Gallinat J, Fehr C, Giegling I,
Lamina C, Illig T, Müller H, Raum E, Rothenbacher D, Wichmann HE,
Brenner H, Winterer G.
Association of nicotinic acetylcholine receptor subunit alpha-4
polymorphisms with nicotine dependence in 5500 Germans.
The Pharmacogenomics Journal 2009; 9: 219-224.
Gao L,
Weck MN, Nieters A, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to
15 Helicobacter pylori proteins measured by multiple serology.
European Journal of Cancer; 69: 2973-2980.
Gao L, Weck MN, Stegmaier C, Rothenbacher D,
Brenner H.
Alcohol consumption and chronic atrophic
gastritis: population-based study among 9444 older adults from Germany.
International Journal of Cancer 2009;
125:2918-2922.
The Emerging Risk Factors Collaboration.*
Major lipids, apolipoproteins and risk of
vascular disease.
JAMA 2009; 302: 1993-2000.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
2008
Raum E, Lietzau S, Stegmaier C, Brenner H., Rothenbacher D.
For the majority of patients with diabetes blood pressure and lipid
management is not in line with recommendations. Results from a large
population-based cohort in Germany.
Pharmacoepidemiology and Drug Safety 2008; 17: 485-494.
Widschwendter
M, Apostolidou S, Raum E, Rothenbacher D, Fiegl H, Menon U, Stegmaier
C, Jacobs IJ, Brenner H.
Epigenotyping in peripheral blood cell DNA and breast cancer risk: a
proof of principle study.
PloS ONE 2008; 3: e2656.
Müller H, Haug U, Rothenbacher D, Stegmaier C,
Brenner H.
Evaluation of serum and urine MRP-14 as marker for early detection of
prostate cancer.
Journal of Urology 2008; 180: 1309-1313.
2007
Haug U, Hillebrand T, Bendzko P, Löw M, Rothenbacher D, Stegmaier C,
Brenner H.
Mutant-enriched PCR and allele-specific hybridization reaction to
detect K-ras-mutations in stool DNA: High prevalence in a large sample
of older adults.
Clinical Chemistry 2007; 53: 787-790.
Wolkewitz
M, Rothenbacher D, Löw M, Stegmaier C, Ziegler H, Radulescu M, Brenner
H, Diepgen TL.
Lifetime prevalence of self-reported atopic diseases in a
population-based sample of elderly: results of the ESTHER-study.
British Journal of Dermatology 2007; 156: 693-697.
Haug U,
Rothenbacher D, Wente MN, Seiler CM, Stegmaier C, Brenner H.
Tumor M2-PK as a stool marker for colorectal cancer: comparative
analysis in a large sample of unselected older adults versus colorectal
cancer patients.
British Journal of Cancer 2007; 96: 1329-1334.
Raum E,
Rothenbacher D, Ziegler H, Brenner H.
Heavy physical activity – risk or protective factor for cardiovascular
disease? A life course perspective.
Annals of Epidemiology 2007; 17: 417-424.
Weck
MN, Stegmaier C, Rothenbacher D, Brenner H.
Epidemiology of chronic atrophic gastritis: population based study
among 9,444 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2007; 26: 879-887.
Brenner
H, Rothenbacher D, Weck MN.
Epidemiologic findings on serologically defined chronic atrophic
gastritis strongly depend on the choice of the cutoff-value.
International Journal of Cancer 2007; 121: 2782-2786.
Raum E, Rothenbacher D, Löw M, Stegmaier C,
Ziegler H, Brenner H.
Changes of cardiovascular risk factors and their implications in
subsequent birth cohorts of older adults in Germany: a life course
approach.
European Journal of Cardiovascular Prevention and Rehabilitation 2007;
14: 809-814.
2006
Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The diagnosis of a smoking-related disease is a prominent trigger for
smoking cessation in a retrospective cohort study.
Journal of Clinical Epidemiology 2006; 59: 82-89.
Twardella
D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The impact of body weight on smoking cessation in German adults.
Preventive Medicine 2006; 42: 109-113.
Wang H, Rothenbacher D, Löw M, Stegmaier C,
Brenner H, Diepgen TL.
Atopic diseases, immunoglobulin E and risk of cancer of the prostate,
breast, lung und colorectum.
International
Journal of Cancer 2006; 119: 695-701.
2004
Löw M, Stegmaier C, Ziegler H, Rothenbacher D, Brenner H.
Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und
optimierten Therapie chronischer Erkrankungen in der älteren
Bevölkerung (ESTHER-Studie).
Deutsche Medizinische Wochenschrift 2004; 129: 2643-2647.
Bergk V, Gasse C, Rothenbacher D, Loew M, Brenner H, Haefeli
WE.
Drug
interactions in primary care: impact of a new algorithm on risk
determination.
Clinical Pharmacology and Therapeutics 2004; 76: 85-96.
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