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Publikationen
2018
Adams C, Richmond RC, Santos Ferreira DL, […], Brenner H et al.
Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in
the ProtecT Study. Cancer Epidemiol Biomarkers Prev. 2018 Oct 23.
doi:10.1158/1055-9965.Epi-18-0079.
Dadaev T, Saunders EJ, Newcombe PJ, […],
Brenner H et al. Fine-mapping of prostate cancer susceptibility loci in a large
meta-analysis identifies candidate causal variants. Nat Commun. 2018 Jun
11;9(1):2256. doi:10.1038/s41467-018-04109-8.
Gao X, Brenner H, Holleczek B, Cuk K, Zhang Y, Anusruti A, Xuan Y,
Xu Y, Schöttker B. Urinary 8-isoprostane levels and occurrence of lung,
colorectal, prostate, breast and overall cancer: Results from a large,
population-based cohort study with 14 years of follow-up. Free Radic Biol
Med. 2018 Aug 1;123:20-6.
doi:10.1016/j.freeradbiomed.2018.05.065.
Gao X, Zhang Y, Mons U, Brenner H. Leukocyte telomere length and
epigenetic-based mortality risk score: associations with all-cause
mortality among older adults. Epigenetics. 2018;13(8):846-57.
doi:10.1080/15592294.2018.1514853.
Gao X, Zhang Y, Schöttker B, Brenner H. Vitamin D status and
epigenetic-based mortality risk score: strong independent and joint
prediction of all-cause mortality in a population-based cohort study.
Clin Epigenetics. 2018;10:84. doi:10.1186/s13148-018-0515-y.
Lophatananon A, Stewart-Brown S, Kote-Jarai Z, […], Brenner H et
al. Height, selected genetic markers and prostate cancer risk: results
from the PRACTICAL consortium. Br J
Cancer. 2018 Mar 20;118(6):e16. doi:10.1038/bjc.2018.6.
Matejcic M, Saunders EJ, Dadaev T, […],
Brenner H et al. Germline variation at 8q24 and prostate cancer risk in men of
European ancestry. Nat Commun. 2018 Nov 5;9(1):4616.
doi:10.1038/s41467-018-06863-1.
Muhlack DC, Hoppe LK, Stock C, Haefeli WE, Brenner H, Schöttker B.
The associations of geriatric syndromes and other patient characteristics
with the current and future use of potentially inappropriate medications
in a large cohort study. Eur J Clin Pharmacol. 2018 Dec;74(12):1633-44.
doi:10.1007/s00228-018-2534-1.
Nabers A, Perna L, Lange J, Mons U, Schartner J, Guldenhaupt J,
Saum KU, Janelidze S, Holleczek B, Rujescu D, Hansson O, Gerwert K,
Brenner H. Amyloid blood biomarker detects Alzheimer's disease. EMBO Mol
Med. 2018 May;10(5).
doi:10.15252/emmm.201708763.
Saunders EJ, Dadaev T, Leongamornlert DA,
[…], Brenner H et al. Gene and pathway level analyses
of germline DNA-repair gene variants and prostate cancer susceptibility
using the iCOGS-genotyping array. Br J Cancer. 2018 Mar 20;118(6):e9. doi:10.1038/bjc.2017.468.
Schöttker B, Muhlack DC, Hoppe LK, Holleczek B, Brenner H. Updated
analysis on polypharmacy and mortality from the ESTHER study. Eur J Clin Pharmacol. 2018 Jul;74(7):981-2. doi:10.1007/s00228-018-2445-1.
Schumacher FR, Al Olama AA, Berndt SI,
[…], Brenner H et al. Association analyses of more
than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet. 2018 Jul;50(7):928-36.
doi:10.1038/s41588-018-0142-8.
Seibert TM, Fan CC, Wang Y, […], Brenner H
et al. Polygenic hazard score to guide screening for aggressive prostate
cancer: development and validation in large scale cohorts. Bmj. 2018 Jan
10;360:j5757. doi:10.1136/bmj.j5757.
Wu L, Shi W, Long J, Guo X, […], Brenner H
et al. A transcriptome-wide association study of 229,000 women identifies
new candidate susceptibility genes for breast cancer. Nat Genet. 2018 Jul;50(7):968-78. doi:10.1038/s41588-018-0132-x.
Xuan Y, Bobak M, Anusruti A, Jansen E, Pajak A, Tamosiunas A, Saum
KU, Holleczek B, Gao X, Brenner H, Schöttker B. Association of serum
markers of oxidative stress with myocardial infarction and stroke: pooled
results from four large European cohort studies. Eur J Epidemiol. 2018
Nov 7. doi:10.1007/s10654-018-0457-x.
Xuan Y, Gao X, Holleczek B, Brenner H, Schöttker
B. Prediction of myocardial infarction, stroke and cardiovascular
mortality with urinary biomarkers of oxidative stress: Results from a
large cohort study. Int J Cardiol. 2018 Dec 15;273:223-9.
doi:10.1016/j.ijcard.2018.08.002.
Zhang Y, Saum KU, Schöttker B, Holleczek B, Brenner H. Methylomic
survival predictors, frailty, and mortality. Aging (Albany NY). 2018 Mar
6;10(3):339-57. doi:10.18632/aging.101392.
2017
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in
blood pressure from 1975 to 2015: a pooled analysis of 1479
population-based measurement studies with 19.1 million participants.
Lancet. 2017 Jan 7;389(10064):37-55. doi:10.1016/s0140-6736(16)31919-5.
Boehlen FH, Herzog W, Schellberg D, Maatouk I, Saum KU, Brenner H,
Wild B. Self-perceived coping resources of middle-aged and older adults -
results of a large population-based study. Aging Ment Health. 2017 Dec;21(12):1303-9. doi:10.1080/13607863.2016.1220918.
Brenner H, Jansen L, Saum KU, Holleczek B, Schöttker B. Vitamin D
Supplementation Trials Aimed at Reducing Mortality Have Much Higher Power
When Focusing on People with Low Serum 25-Hydroxyvitamin D
Concentrations. J Nutr.
2017 Jul;147(7):1325-33. doi:10.3945/jn.117.250191.
Brunner C, Davies NM, Martin RM, […],
Brenner H et al. Alcohol consumption and prostate cancer incidence and progression:
A Mendelian randomisation study. Int J Cancer. 2017 Jan 1;140(1):75-85. doi:10.1002/ijc.30436.
Day FR, Thompson DJ, Helgason H, […], Brenner H et al. Genomic
analyses identify hundreds of variants associated with age at menarche
and support a role for puberty timing in cancer risk. Nat Genet. 2017 Jun;49(6):834-41. doi:10.1038/ng.3841.
Dimitrakopoulou VI, Tsilidis KK, Haycock PC et al. The PRACTICAL
Consortium. Circulating vitamin D concentration and risk of seven
cancers: Mendelian randomisation study. Bmj. 2017 Oct 31;359:j4761. doi:10.1136/bmj.j4761.
Gao X, Thomsen H, Zhang Y, Breitling LP, Brenner H. The impact of
methylation quantitative trait loci (mQTLs) on active smoking-related DNA
methylation changes. Clin Epigenetics. 2017;9:87.
doi:10.1186/s13148-017-0387-6.
Heiss JA, Brenner H. Impact of confounding by leukocyte
composition on associations of leukocyte DNA methylation with common risk
factors. Epigenomics. 2017 May;9(5):659-68. doi:10.2217/epi-2016-0154.
Lin HY, Chen DT, Huang PY, […], Brenner H et al. SNP interaction
pattern identifier (SIPI): an intensive search for SNP-SNP interaction
patterns. Bioinformatics. 2017 Mar 15;33(6):822-33.
doi:10.1093/bioinformatics/btw762.
Mayer T, Meid AD, Saum KU, Brenner H,
Schöttker B, Seidling HM, Haefeli WE. Comparison of Nine Instruments
to Calculate Anticholinergic Load in a Large Cohort of Older Outpatients:
Association with Cognitive and Functional Decline, Falls, and Use of
Laxatives. Am J Geriatr Psychiatry. 2017 May;25(5):531-40.
doi:10.1016/j.jagp.2017.01.009.
Mons U, Muezzinler A, Schöttker B, Dieffenbach AK, Butterbach K,
Schick M, Peasey A, De Vivo I, Trichopoulou A, Boffetta P, Brenner H.
Leukocyte Telomere Length and All-Cause, Cardiovascular Disease, and
Cancer Mortality: Results From Individual-Participant-Data Meta-Analysis
of 2 Large Prospective Cohort Studies. Am J Epidemiol. 2017 Jun 15;185(12):1317-26. doi:10.1093/aje/kww210.
Ordonez-Mena JM, Maalmi H, Schöttker B, Saum KU, Holleczek B, Wang
TJ, Burwinkel B, Brenner H. Genetic Variants in the Vitamin D Pathway,
25(OH)D Levels, and Mortality in a Large Population-Based Cohort Study. J
Clin Endocrinol Metab. 2017 Feb 1;102(2):470-7.
doi:10.1210/jc.2016-2468.
Ordonez-Mena JM, Schöttker B, Saum KU, Holleczek B, Burwinkel B,
Wang TJ, Brenner H. No Association of Vitamin D Pathway Genetic Variants
with Cancer Risks in a Population-Based Cohort of German Older Adults.
Cancer Epidemiol Biomarkers Prev. 2017 Sep;26(9):1459-61.
doi:10.1158/1055-9965.epi-17-0191.
Saum KU, Schöttker B, Meid AD, Holleczek B, Haefeli WE, Hauer K,
Brenner H. Is Polypharmacy Associated with Frailty in Older People?
Results From the ESTHER Cohort Study. J Am Geriatr Soc. 2017 Feb;65(2):e27-e32.
Schöttker B, Saum KU, Muhlack DC, Hoppe LK, Holleczek B, Brenner
H. Polypharmacy and mortality: new insights from a large cohort of older
adults by detection of effect modification by multi-morbidity and
comprehensive correction of confounding by indication. Eur J Clin
Pharmacol. 2017 Aug;73(8):1041-8. doi:10.1007/s00228-017-2266-7.
Steele CJ, Schöttker B, Marshall AH, Kouvonen A, O'Doherty MG,
Mons U, Saum KU, Boffetta P, Trichopoulou A, Brenner H, Kee F. Education
achievement and type 2 diabetes-what mediates the relationship in older
adults? Data from the ESTHER study: a population-based cohort study. BMJ
Open. 2017 Apr 17;7(4):e013569. doi:10.1136/bmjopen-2016-013569.
Sud A, Thomsen H, Law PJ et al. The PRACTICAL Consortium.
Genome-wide association study of classical Hodgkin lymphoma identifies
key regulators of disease susceptibility. Nat Commun. 2017 Dec 1;8(1):1892. doi:10.1038/s41467-017-00320-1.
Taylor AE, Martin RM, Geybels MS, […], Brenner H et al.
Investigating the possible causal role of coffee consumption with
prostate cancer risk and progression using Mendelian randomization
analysis. Int J Cancer. 2017 Jan 15;140(2):322-8.
doi:10.1002/ijc.30462.
Zhang Y, Hapala J, Brenner H, Wagner W. Individual CpG sites that
are associated with age and life expectancy become hypomethylated upon
aging. Clin Epigenetics. 2017;9:9. doi:10.1186/s13148-017-0315-9.
Zhang Y, Wilson R, Heiss J, Breitling LP, Saum KU, Schöttker B,
Holleczek B, Waldenberger M, Peters A, Brenner H. DNA methylation
signatures in peripheral blood strongly predict all-cause mortality. Nat
Commun. 2017 Mar 17;8:14617. doi:10.1038/ncomms14617.
Zuber V, Bettella F, Witoelar A, Andreassen OA, Mills IG,
Urbanucci A. The PRACTICAL Consortium. Bromodomain protein 4
discriminates tissue-specific super-enhancers containing disease-specific
susceptibility loci in prostate and breast cancer. BMC Genomics. 2017 Mar
31;18(1):270. doi:10.1186/s12864-017-3620-y.
2016
Bock JO, König HH, Brenner H,
Haefeli WE, Quinzler R, Matschinger H, Saum KU, Schöttker B, Heider D.
Associations of frailty with health care costs - results of the ESTHER
cohort study. BMC Health Serv Res. 2016 Apr 14;16(1):128.
doi: 10.1186/s12913-016-1360-3.
Bock JO, Heider D, Matschinger
H, Brenner H, Saum KU, Haefeli WE, Konig HH. Willingness to pay for
health insurance among the elderly population in Germany. Eur J Health
Econ. 2016 Mar;17(2):149-58. doi:10.1007/s10198-014-0663-8.
Boehlen FH, Herzog W, Maatouk
I, Saum KU, Brenner H, Wild B. [Treatment preferences of elderly patients
with mental disorders]. Z Gerontol Geriatr. 2016 Feb;49(2):120-5.
doi:10.1007/s00391-015-0908-x.
Bonilla C, Lewis SJ, Martin RM,
[…], Brenner H et al. Pubertal development and prostate cancer risk:
Mendelian randomization study in a population-based cohort. BMC Med. 2016
Apr 4;14:66. doi:10.1186/s12916-016-0602-x.
Bonilla C, Lewis SJ, Rowlands
MA, […], Brenner H et al. Assessing the role of insulin-like growth
factors and binding proteins in prostate cancer using Mendelian
randomization: Genetic variants as instruments for circulating levels.
Int J Cancer. 2016 Oct 1;139(7):1520-33.
doi:10.1002/ijc.30206.
Breitling LP, Saum KU, Perna L,
Schöttker B, Holleczek B, Brenner H. Frailty is associated with the
epigenetic clock but not with telomere length in a German cohort. Clin
Epigenetics. 2016;8:21. doi:10.1186/s13148-016-0186-5.
Breitling LP, Saum KU,
Schöttker B, Holleczek B, Herth FJ, Brenner H. Pneumonia in the
Noninstitutionalized Older Population. Dtsch Arztebl Int. 2016
Sep 16;113(37):607-14. doi:10.3238/arztebl.2016.0607.
Brück K,
Stel VS, Gambaro G, […], Brenner H et al. European CKD Burden Consortium. CKD Prevalence Varies across the
European General Population. J Am Soc Nephrol. 2016 Jul;27(7):2135-47.
doi:10.1681/asn.2015050542.
Bull CJ, Bonilla C, Holly JM,
[…], Brenner H et al. Blood lipids and prostate cancer: a Mendelian
randomization analysis. Cancer Med. 2016 Jun;5(6):1125-36.
doi:10.1002/cam4.695.
Chen LS, Baker T, Hung RJ,
Horton A, […], Brenner H et al. Genetic Risk Can Be Decreased: Quitting
Smoking Decreases and Delays Lung Cancer for Smokers With High and Low
CHRNA5 Risk Genotypes - A Meta-Analysis. EBioMedicine. 2016 Sep;11:219-26. doi:10.1016/j.ebiom.2016.08.012.
Chen XZ, Schöttker B, Castro
FA, Chen H, Zhang Y, Holleczek B, Brenner H. Association of helicobacter
pylori infection and chronic atrophic gastritis with risk of colonic,
pancreatic and gastric cancer: A ten-year follow-up of the ESTHER cohort
study. Oncotarget. 2016 Mar 29;7(13):17182-93. doi: 10.18632/oncotarget.7946.
Fehringer G, Kraft P, Pharoah
PD, […], Brenner H et al. Cross-Cancer Genome-Wide Analysis of Lung,
Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic
Associations. Cancer Res. 2016 Sep 1;76(17):5103-14.
doi:10.1158/0008-5472.can-15-2980.
Florath I, Butterbach K, Heiss
J, Bewerunge-Hudler M, Zhang Y, Schöttker B, Brenner H. Type 2 diabetes
and leucocyte DNA methylation: an epigenome-wide association study in
over 1,500 older adults. Diabetologia. 2016 Jan;59(1):130-8.
doi:10.1007/s00125-015-3773-7.
Fuchs J, Scheidt-Nave C,
Gaertner B, Dapp U, von Renteln-Kruse W, Saum KU, Thorand B, Strobl R,
Grill E. [Frailty in Germany: status and perspectives : Results from a
workshop of the German Society for Epidemiology]. Z Gerontol Geriatr.
2016 Dec;49(8):734-42. doi:10.1007/s00391-015-0999-4.
Gao X, Mons U, Zhang Y,
Breitling LP, Brenner H. DNA methylation changes in response to active
smoking exposure are associated with leukocyte telomere length among
older adults. Eur J Epidemiol. 2016 Dec;31(12):1231-41.
doi:10.1007/s10654-016-0210-2.
Gao X, Zhang Y, Breitling LP,
Brenner H. Tobacco smoking and methylation of genes related to lung
cancer development. Oncotarget. 2016 Sep 13;7(37):59017-28.
doi:10.18632/oncotarget.10007.
Gao X, Zhang Y, Breitling LP,
Brenner H. Relationship of tobacco smoking and smoking-related DNA
methylation with epigenetic age acceleration. Oncotarget. 2016 Jul 26;7(30):46878-89. doi:10.18632/oncotarget.9795.
Gusev A, Shi H, Kichaev G,
Pomerantz M, […], Brenner H et al. The PRACTICAL Consortium. Atlas of
prostate cancer heritability in European and African-American men
pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 7;7:10979. doi:10.1038/ncomms10979.
Hajek A,
Bock JO, Saum KU, Schöttker B, Brenner H, Heider D, Konig HH. [Morbidity Differences by Health Insurance
Status in Old Age]. Gesundheitswesen. 2016 Jun 28. doi:10.1055/s-0042-108584.
Kar SP, Beesley J, Amin Al
Olama A, [...], Brenner H et al. The PRACTICAL Consortium. Genome-Wide
Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies
Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer
Types. Cancer Discov. 2016 Sep;6(9):1052-67.
doi:10.1158/2159-8290.cd-15-1227.
Khankari NK, Murff HJ, Zeng C,
[…], Brenner H et al. The PRACTICAL Consortium. Polyunsaturated fatty
acids and prostate cancer risk: a Mendelian randomisation analysis from
the PRACTICAL consortium. Br J Cancer. 2016 Aug 23;115(5):624-31.
doi:10.1038/bjc.2016.228.
Lechner S, Herzog W, Boehlen F,
Maatouk I, Saum KU, Brenner H, Wild B. Control preferences in treatment
decisions among older adults - Results of a large population-based study.
J Psychosom Res. 2016 Jul;86:28-33.
doi:10.1016/j.jpsychores.2016.05.004.
Maatouk I, Herzog W, Bohlen F,
Quinzler R, Lowe B, Saum KU, Brenner H, Wild B. Association of
hypertension with depression and generalized anxiety symptoms in a large
population-based sample of older adults. J Hypertens. 2016
Sep;34(9):1711-20. doi:10.1097/hjh.0000000000001006.
Meid AD,
Quinzler R, Groll A, Wild B, Saum KU, Schöttker B, Heider D, Konig HH,
Brenner H, Haefeli WE. Longitudinal
evaluation of medication underuse in older outpatients and its
association with quality of life. Eur J Clin Pharmacol. 2016 Jul;72(7):877-85. doi:10.1007/s00228-016-2047-8.
Muezzinler A, Mons U,
Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P,
Holleczek B, Stegmaier C, Brenner H. Body mass index and leukocyte
telomere length dynamics among older adults: Results from the ESTHER
cohort. Exp Gerontol. 2016 Feb;74:1-8.
doi:10.1016/j.exger.2015.11.019.
NCD Risk Factor Collaboration
(NCD-RisC).
Worldwide trends in diabetes
since 1980: a pooled analysis of 751 population-based studies with 4.4
million participants. Lancet. 2016 Apr 9;387(10027):1513-30.
doi:10.1016/s0140-6736(16)00618-8.
NCD Risk Factor Collaboration
(NCD-RisC).
Trends in adult body-mass index
in 200 countries from 1975 to 2014: a pooled analysis of 1698
population-based measurement studies with 19.2 million participants.
Lancet. 2016 Apr 2;387(10026):1377-96. doi:10.1016/s0140-6736(16)30054-x.
NCD Risk Factor Collaboration
(NCD-RisC).
A century of trends in adult
human height. Elife. 2016 Jul 26;5.
doi:10.7554/eLife.13410.
O'Doherty MG, Cairns K, O'Neill
V, Lamrock F, Jorgensen T, Brenner H, Schöttker B, Wilsgaard T, Siganos
G, Kuulasmaa K, Boffetta P, Trichopoulou A, Kee F. Effect of major
lifestyle risk factors, independent and jointly, on life expectancy with
and without cardiovascular disease: results from the Consortium on Health
and Ageing Network of Cohorts in Europe and the United States (CHANCES).
Eur J Epidemiol. 2016 May;31(5):455-68. doi:10.1007/s10654-015-0112-8.
Ordóñez-Mena JM, Schöttker B,
Mons U, […], Brenner H; Consortium on Health and Ageing: Network of
Cohorts in Europe and the United States (CHANCES). Quantification of the
smoking-associated cancer risk with rate advancement periods:
meta-analysis of individual participant data from cohorts of the CHANCES
consortium.
BMC Med. 2016 Apr 5;14(1):62. doi:
10.1186/s12916-016-0607-5.
Ordonez-Mena JM, Schöttker B,
Fedirko V, Jenab M, Olsen A, Halkjaer J, Kampman E, de Groot L, Jansen E,
Bueno-de-Mesquita HB, Peeters PH, Siganos G, Wilsgaard T, Perna L,
Holleczek B, Pettersson-Kymmer U, Orfanos P, Trichopoulou A, Boffetta P,
Brenner H. Pre-diagnostic vitamin D concentrations and cancer risks in
older individuals: an analysis of cohorts participating in the CHANCES
consortium. Eur J Epidemiol. 2016 Mar;31(3):311-23.
doi:10.1007/s10654-015-0040-7.
Perna L, Mons U, Rujescu D,
Kliegel M, Brenner H. Apolipoprotein E e4 and Cognitive Function: A
Modifiable Association Results from Two Independent Cohort Studies.
Dement Geriatr Cogn Disord. 2016;41(1-2):35-45. doi:10.1159/000440697.
Perna L, Zhang Y, Mons U,
Holleczek B, Saum KU, Brenner H. Epigenetic age acceleration predicts
cancer, cardiovascular, and all-cause mortality in a German case cohort. Clin
Epigenetics. 2016;8:64.
doi:10.1186/s13148-016-0228-z.
Schmidt MK,
Hogervorst F, van Hien R, […], Brenner H et al. Age- and Tumor Subtype-Specific Breast Cancer
Risk Estimates for CHEK2*1100delC Carriers. J Clin Oncol. 2016 Aug 10;34(23):2750-60. doi:10.1200/jco.2016.66.5844.
Schöttker B, Rathmann W, Herder
C, Thorand B, Wilsgaard T, Njolstad I, Siganos G, Mathiesen EB, Saum KU,
Peasey A, Feskens E, Boffetta P, Trichopoulou A, Kuulasmaa K, Kee F,
Brenner H. HbA1c levels in non-diabetic older adults - No J-shaped
associations with primary cardiovascular events, cardiovascular and
all-cause mortality after adjustment for confounders in a meta-analysis
of individual participant data from six cohort studies. BMC Med. 2016 Feb
11;14:26. doi:10.1186/s12916-016-0570-1.
Schöttker B, Saum KU, Jansen
EH, Holleczek B, Brenner H. Associations of metabolic, inflammatory and
oxidative stress markers with total morbidity and multi-morbidity in a
large cohort of older German adults. Age Ageing. 2016 Jan;45(1):127-35. doi:10.1093/ageing/afv159.
Shi J, Park JH, Duan J, Berndt
ST, […], Brenner H et al. Winner's Curse Correction and Variable
Thresholding Improve Performance of Polygenic Risk Modeling Based on
Genome-Wide Association Study Summary-Level Data. PLoS Genet. 2016 Dec;12(12):e1006493. doi:10.1371/journal.pgen.1006493.
Walter V, Jansen L, Hoffmeister
M, Ulrich A, Roth W, Blaker H, Chang-Claude J, Brenner H. Prognostic
relevance of prediagnostic weight loss and overweight at diagnosis in
patients with colorectal cancer. Am J Clin Nutr. 2016 Oct;104(4):1110-20. doi:10.3945/ajcn.116.136531.
Walter V, Jansen L, Ulrich A,
Roth W, Blaker H, Chang-Claude J, Hoffmeister M, Brenner H. Alcohol
consumption and survival of colorectal cancer patients: a
population-based study from Germany. Am J Clin Nutr. 2016 Jun;103(6):1497-506. doi:10.3945/ajcn.115.127092.
Zhang Y, Florath I, Saum KU,
Brenner H. Self-reported smoking, serum cotinine, and blood DNA
methylation. Environ Res. 2016 Apr;146:395-403.
doi:10.1016/j.envres.2016.01.026.
2015
Amin Al Olama A, Benlloch S, Antoniou AC, […], Brenner H et al. Risk
Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium,
Using 25 Known Prostate Cancer Susceptibility Loci. Cancer Epidemiol
Biomarkers Prev. 2015 Jul;24(7):1121-9.
doi:10.1158/1055-9965.epi-14-0317.
Amin Al Olama A, Dadaev T,
Hazelett DJ, […], Brenner H et al. Multiple novel prostate cancer
susceptibility signals identified by fine-mapping of known risk loci
among Europeans. Hum Mol Genet. 2015 Oct 1;24(19):5589-602.
doi:10.1093/hmg/ddv203.
Benetou V, Orfanos P, Feskanich
D, Michaelsson K, Pettersson-Kymmer U, Ahmed LA, Peasey A, Wolk A,
Brenner H, Bobak M, Wilsgaard T, Schöttker B, Saum KU, Bellavia A,
Grodstein F, Klinaki E, Valanou E, Papatesta EM, Boffetta P, Trichopoulou
A. Education, marital status, and risk of hip fractures in older men and
women: the CHANCES project. Osteoporos Int. 2015 Jun;26(6):1733-46.
doi:10.1007/s00198-015-3054-9.
Boehlen F, Herzog W, Quinzler
R, Haefeli WE, Maatouk I, Niehoff D, Saum KU, Brenner H, Wild B.
Loneliness in the elderly is associated with the use of psychotropic
drugs. Int J Geriatr Psychiatry. 2015 Sep;30(9):957-64.
doi:10.1002/gps.4246.
Bozorgmehr K, Maier W, Brenner
H, Saum KU, Stock C, Miksch A, Holleczek B, Szecsenyi J, Razum O. Social
disparities in Disease Management Programmes for coronary heart disease
in Germany: a cross-classified multilevel analysis. J Epidemiol Community
Health. 2015 Nov;69(11):1091-101. doi:10.1136/jech-2014-204506.
Bozorgmehr K, San Sebastian M,
Brenner H, Razum O, Maier W, Saum KU, Holleczek B, Miksch A, Szecsenyi J.
Analysing horizontal equity in enrolment in Disease Management Programmes
for coronary heart disease in Germany 2008-2010. Int J Equity Health.
2015 Mar 10;14:28. doi:10.1186/s12939-015-0155-1.
Cheng TH, Thompson D, Painter
J, […], Brenner H et al. Meta-analysis of genome-wide association studies
identifies common susceptibility polymorphisms for colorectal and
endometrial cancer near SH2B3 and TSHZ1.
Sci Rep. 2015 Dec 1;5:17369. doi:
10.1038/srep17369.
Davies NM,
Gaunt TR, Lewis SJ, […], Brenner H et al. The effects of height and BMI on prostate cancer incidence and
mortality: a Mendelian randomization study in 20,848 cases and 20,214
controls from the PRACTICAL consortium. Cancer Causes Control. 2015 Nov;26(11):1603-16. doi:10.1007/s10552-015-0654-9.
Day FR, Ruth KS, Thompson DJ,
[…], Brenner H et al. The BCAC Breast Cancer Association Consortium.
Large-scale genomic analyses link reproductive aging to hypothalamic
signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Nat Genet. 2015 Nov;47(11):1294-303.
doi:10.1038/ng.3412.
Emrich IE, Pickering JW,
Schöttker B, Lennartz CS, Rogacev KS, Brenner H, Rothenbacher D,
Holleczek B, Saum KU, Fliser D, Heine GH. Comparison of the performance
of 2 GFR estimating equations using creatinine and cystatin C to predict
adverse outcomes in elderly individuals. Am J Kidney Dis. 2015 Apr;65(4):636-8. doi:10.1053/j.ajkd.2014.12.006.
Freigofas J, Seidling HM,
Quinzler R, Schöttker B, Saum KU, Brenner H, Haefeli WE. Characteristics
of medication schedules used by elderly ambulatory patients. Eur J Clin
Pharmacol. 2015 Sep;71(9):1109-20. doi:10.1007/s00228-015-1888-x.
Laitinen VH, Rantapero T,
Fischer D, Vuorinen EM, Tammela TL, Wahlfors T, Schleutker J. The PRACTICAL
Consortium. Fine-mapping the 2q37 and 17q11.2-q22 loci for novel genes
and sequence variants associated with a genetic predisposition to
prostate cancer. Int J Cancer. 2015 May 15;136(10):2316-27.
doi:10.1002/ijc.29276.
Meid AD, Quinzler R, Freigofas
J, Saum KU, Schöttker B, Holleczek B, Heider D, Konig HH, Brenner H,
Haefeli WE. Medication Underuse in Aging Outpatients with Cardiovascular
Disease: Prevalence, Determinants, and Outcomes in a Prospective Cohort
Study. PLoS One. 2015;10(8):e0136339. doi:10.1371/journal.pone.0136339.
Muezzinler A, Mons U,
Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P,
Holleczek B, Stegmaier C, Brenner H. Smoking habits and leukocyte
telomere length dynamics among older adults: Results from the ESTHER
cohort. Exp Gerontol. 2015 Oct;70:18-25.
doi:10.1016/j.exger.2015.07.002.
Muezzinler A, Mons U, Gellert
C, Schöttker B, Jansen E, Kee F, O'Doherty MG, Kuulasmaa K, Freedman ND,
Abnet CC, Wolk A, Hakansson N, Orsini N, Wilsgaard T, Bueno-de-Mesquita
B, van der Schouw YT, Peeters PHM, de Groot L, Peters A, Orfanos P,
Linneberg A, Pisinger C, Tamosiunas A, Baceviciene M, Luksiene D,
Bernotiene G, Jousilahti P, Petterson-Kymmer U, Jansson JH, Soderberg S,
Eriksson S, Jankovic N, Sanchez MJ, Veronesi G, Sans S, Drygas W,
Trichopoulou A, Boffetta P, Brenner H. Smoking and All-cause Mortality in
Older Adults: Results From the CHANCES Consortium. Am J Prev Med. 2015
Nov;49(5):e53-e63.
doi:10.1016/j.amepre.2015.04.004.
Painter JN, O'Mara TA, Batra J,
[…], Brenner H et al. Fine-mapping of the HNF1B multicancer locus
identifies candidate variants that mediate endometrial cancer risk. Hum
Mol Genet. 2015 Mar 1;24(5):1478-92.
doi:10.1093/hmg/ddu552.
Perna L, Wahl HW, Mons U, Saum
KU, Holleczek B, Brenner H. Cognitive impairment, all-cause and
cause-specific mortality among non-demented older adults. Age Ageing.
2015 May;44(3):445-51.
doi:10.1093/ageing/afu188.
Saum KU, Dieffenbach AK, Jansen
EH, Schöttker B, Holleczek B, Hauer K, Brenner H. Association between
Oxidative Stress and Frailty in an Elderly German Population: Results
from the ESTHER Cohort Study. Gerontology. 2015;61(5):407-15.
doi:10.1159/000380881.
Schöttker B, Brenner H. Vitamin
D as a Resilience Factor, Helpful for Survival of Potentially Fatal Conditions:
A Hypothesis Emerging from Recent Findings of the ESTHER Cohort Study and
the CHANCES Consortium. Nutrients. 2015 May 6;7(5):3264-78.
doi:10.3390/nu7053264.
Schöttker B, Brenner H, Jansen
EH, Gardiner J, Peasey A, Kubinova R, Pajak A, Topor-Madry R, Tamosiunas
A, Saum KU, Holleczek B, Pikhart H, Bobak M. Evidence for the free
radical/oxidative stress theory of ageing from the CHANCES consortium: a
meta-analysis of individual participant data. BMC Med. 2015 Dec 15;13:300. doi:10.1186/s12916-015-0537-7.
Schöttker B, Saum KU, Jansen
EH, Boffetta P, Trichopoulou A, Holleczek B, Dieffenbach AK, Brenner H.
Oxidative stress markers and all-cause mortality at older age: a
population-based cohort study. J Gerontol A Biol Sci Med Sci. 2015 Apr;70(4):518-24. doi:10.1093/gerona/glu111.
Schöttker B, Zhang Y, Heiss JA,
Butterbach K, Jansen EH, Bewerunge-Hudler M, Saum KU, Holleczek B,
Brenner H. Discovery of a novel epigenetic cancer marker related to the
oxidative status of human blood. Genes Chromosomes Cancer. 2015 Sep;54(9):583-94. doi:10.1002/gcc.22271.
Stegeman S, Amankwah E, Klein
K, […], Brenner H et al. A Large-Scale Analysis of Genetic Variants
within Putative miRNA Binding Sites in Prostate Cancer. Cancer Discov.
2015 Apr;5(4):368-79. doi:10.1158/2159-8290.cd-14-1057.
Szulkin R, Karlsson R,
Whitington T, […], Brenner H et al. Genome-wide association study of
prostate cancer-specific survival. Cancer Epidemiol Biomarkers Prev. 2015
Nov;24(11):1796-800.
doi:10.1158/1055-9965.epi-15-0543.
Szulkin R, Whitington T, Eklund
M, […], Brenner H et al. Prediction of individual genetic risk to
prostate cancer using a polygenic score. Prostate. 2015 Sep;75(13):1467-74. doi:10.1002/pros.23037.
Vart P, Bakker SJ, Schöttker B,
de Zeeuw D, Rothenbacher D, Brenner H, Heerspink HJ, Saum KU, Reijneveld
SA, Bültmann U, Koenig W, Gansevoort RT. Relevance of correction for
drift and day-to-day variation in cystatin C measurement: a post-hoc
analysis of the PREVEND cohort, with independent replication in the ESTHER
cohort. Clin Chem Lab Med. 2015 Aug;53(9):1381-90.
doi: 10.1515/cclm-2014-0894.
Walter V, Jansen L, Hoffmeister
M, Ulrich A, Chang-Claude J, Brenner H. Smoking and survival of
colorectal cancer patients: population-based study from Germany. Int J
Cancer. 2015 Sep 15;137(6):1433-45.
doi:10.1002/ijc.29511.
Winn DM, Lee YC, Hashibe M,
Boffetta P. The INHANCE consortium: toward a better understanding of the
causes and mechanisms of head and neck cancer. Oral Dis. 2015 Sep;21(6):685-93. doi:10.1111/odi.12342.
Zhang Y, Schöttker B,
Ordonez-Mena J, Holleczek B, Yang R, Burwinkel B, Butterbach K, Brenner
H. F2RL3 methylation, lung cancer incidence and mortality. Int J
Cancer. 2015 Oct 1;137(7):1739-48. doi:10.1002/ijc.29537.
2014
Agarwal D, Pineda S, Michailidou K, [...], Brenner H, Dieffenbach AK,
Arndt V, Stegmaier C et al. FGF
receptor genes and breast cancer susceptibility: results from the Breast
Cancer Association Consortium. Br J Cancer. 2014 Feb 18; 110(4):
1088–1100. Published online 2014 Feb 18. doi:
10.1038/bjc.2013.769.
Al Olama
AA, Kote-Jarai Z, Berndt SI, […], Brenner H et al. A meta-analysis of 87,040 individuals
identifies 23 new susceptibility loci for prostate cancer. Nat Genet.
2014 Oct;46(10):1103-9. doi:10.1038/ng.3094.
Bock JO,
Matschinger H, Brenner H, Wild B, Haefeli WE, Quinzler R, Saum KU, Heider
D, König HH. Inequalities in out-of-pocket
payments for health care services among elderly Germans--results of a
population-based cross-sectional study. Int J Equity Health. 2014 Jan 8;13(1):3. doi:
10.1186/1475-9276-13-3.
The Emerging Risk Factors
Collaboration*. Glycated hemoglobin measurement and prediction of
cardiovascular disease. JAMA. 2014 Mar 26;311(12):1225-33.
doi: 10.1001/jama.2014.1873.
* Authors on behalf of the
ESTHER study: Brenner H.
Florath I, Butterbach K, Muller
H, Bewerunge-Hudler M, Brenner H. Cross-sectional and longitudinal
changes in DNA methylation with age: an epigenome-wide analysis revealing
over 60 novel age-associated CpG sites. Hum Mol Genet. 2014 Mar 1;23(5):1186-201. doi:10.1093/hmg/ddt531.
Hazelett DJ, Rhie SK, Gaddis M,
Yan C, Lakeland DL, Coetzee SG, Henderson BE, Noushmehr H, Cozen W,
Kote-Jarai Z, Eeles RA, Easton DF, Haiman CA, Lu W, Farnham PJ, Coetzee
GA. The PRACTICAL Consortium. Comprehensive functional annotation of 77
prostate cancer risk loci. PLoS Genet. 2014 Jan;10(1):e1004102.
doi:10.1371/journal.pgen.1004102.
Heider D,
Matschinger H, Müller H, Saum KU, Quinzler R, Haefeli WE, Wild B, Lehnert
T, Brenner H, König HH.
Health care costs in the
elderly in Germany: an analysis applying Andersen's behavioral model of
health care utilization. BMC Health Serv Res. 2014 Feb 14;14:71. doi:
10.1186/1472-6963-14-71.
Jansen L, Hoffmeister M, Arndt V,
Chang-Claude J, Brenner H. Stage-specific associations between beta
blocker use and prognosis after colorectal cancer. Cancer. 2014 Apr 15;120(8):1178-86. doi:10.1002/cncr.28546.
Koch L, Bertram H, Eberle A,
Holleczek B, Schmid-Hopfner S, Waldmann A, Zeissig SR, Brenner H, Arndt
V. Fear of recurrence in long-term breast cancer survivors-still an
issue. Results on prevalence, determinants, and the association with
quality of life and depression from the cancer survivorship--a
multi-regional population-based study. Psychooncology. 2014 May;23(5):547-54. doi:10.1002/pon.3452.
Leoncini E, Ricciardi W, Cadoni
G, […], Brenner H et al. Adult height and head and neck cancer: a pooled
analysis within the INHANCE Consortium. Eur J Epidemiol. 2014 Jan;29(1):35-48. doi:
10.1007/s10654-013-9863-2.
Milne RL, Herranz J,
Michailidou K, […], Brenner H et al. A large-scale assessment of two-way
SNP interactions in breast cancer suceptibility using 46.450 cases and
42.461 controls from the Breast Cancer Association Consortium. Hum Mol
Genet. 2014 Apr 1;23(7):1934-46. doi: 10.1093/hmg/ddt581.
O'Doherty MG, Jorgensen T,
Borglykke A, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kavousi M,
Hughes M, Muezzinler A, Holleczek B, Franco OH, Hofman A, Boffetta P,
Trichopoulou A, Kee F. Repeated measures of body mass index and
C-reactive protein in relation to all-cause mortality and cardiovascular
disease: results from the consortium on health and ageing network of
cohorts in Europe and the United States (CHANCES). Eur J Epidemiol. 2014
Dec;29(12):887-97. doi:10.1007/s10654-014-9954-8.
Pennells L, Kaptoge S, White
IR, Thompson SG, Wood AM; Emerging Risk Factors Collaboration*. Assessing
risk prediction models using individual participant data from multiple
studies. Am J Epidemiol. 2014 Mar 1;179(5):621-32.
doi: 10.1093/aje/kwt298.
* Authors on behalf of the
ESTHER study: Brenner H, Schöttker B, Müller H, Rothenbacher
D.
Perna L, Mons U, Kliegel M,
Brenner H. Serum 25-hydroxyvitamin D and cognitive decline: a
longitudinal study among non-demented older adults. Dement Geriatr Cogn
Disord. 2014;38(3-4):254-63. doi:10.1159/000362870.
Saum KU, Dieffenbach AK,
Müezzinler A, Müller H, Holleczek B, Stegmaier C, Butterbach K, Schick M,
Canzian F, Stammer H, Boukamp P, Hauer K, Brenner H. Frailty and telomere
length: Cross-sectional analysis in 3537 older adults from the ESTHER
cohort. Exp Gerontol. 2014 Aug 21;58C:250-255. doi: 0.1016/j.exger.2014.08.009.
Saum KU, Dieffenbach AK, Muller
H, Holleczek B, Hauer K, Brenner H. Frailty prevalence and 10-year
survival in community-dwelling older adults: results from the ESTHER
cohort study. Eur J Epidemiol. 2014 Mar;29(3):171-9.
doi:10.1007/s10654-014-9891-6.
Saunders
EJ, Dadaev T, Leongamornlert DA, […], Brenner H et al. Fine-mapping the HOXB region detects common
variants tagging a rare coding allele: evidence for synthetic association
in prostate cancer. PLoS Genet. 2014 Feb;10(2):e1004129.
doi:10.1371/journal.pgen.1004129.
Schoeps A, Rudolph A, Seibold
P, […], Brenner H et al. Identification of new genetic susceptibility
loci for breast cancer through consideration of gene-environment
interactions. Genetic Epidemiology 2014; 38: 84-93.
Schöttker B, Saum KU, Perna L,
Ordonez-Mena JM, Holleczek B, Brenner H. Is vitamin D deficiency a cause
of increased morbidity and mortality at older age or simply an indicator
of poor health? Eur J Epidemiol. 2014 Mar;29(3):199-210.
doi:10.1007/s10654-014-9894-3.
Wen CP, Matsushita K, Coresh J,
Iseki K, Islam M, Katz R, McClellan W, Peralta CA, Wang H, de Zeeuw D,
Astor BC, Gansevoort RT, Levey AS, Levin A, and the Chronic Kidney
Disease Prognosis Consortium*. Relative risks of chronic kidney disease
for mortality and end-stage renal disease across races are similar.
Kidney Int. 2014 Feb 12. doi: 10.1038/ki.2013.553.
* Authors on behalf of the
ESTHER study: Rothenbacher D, Brenner H, Müller H, Schöttker B.
Wild B, Eckl A, Herzog W,
Niehoff D, Lechner S, Maatouk I, Schellberg D, Brenner H, Muller H, Lowe B. Assessing generalized anxiety disorder in
elderly people using the GAD-7 and GAD-2 scales: results of a validation
study. Am J Geriatr Psychiatry. 2014 Oct;22(10):1029-38.
doi:10.1016/j.jagp.2013.01.076.
Wild B, Heider D, Maatouk I,
Slaets J, Konig HH, Niehoff D, Saum KU, Brenner H, Sollner W, Herzog W. Significance
and costs of complex biopsychosocial health care needs in elderly people:
results of a population-based study. Psychosom Med. 2014 Sep;76(7):497-502. doi:10.1097/psy.0000000000000080.
Zhang Y, Yang R, Burwinkel B,
Breitling LP, Brenner H. F2RL3 methylation as a biomarker of current and
lifetime smoking exposures. Environmental Health Perspectives 2014; 122:
131-137.
2013
Perna L, Schöttker B, Holleczek B, Brenner H.
Serum 25-hydroxyvitamin D and incidence of fatal and non-fatal
cardiovascular events: a prospective study with repeated measurements.
Journal of Clinical Endocrinology & Metabolism 2013; 98: 4908-4915.
Perna L, Hoffmeister M,
Schöttker B, Arndt V, Haug U, Holleczek B, Burwinkel B, Ordonez-Mena JM,
Brenner H.
Vitamin D receptor polymorphism and colorectal cancer-specific and
all-cause mortality.
Cancer Epidemiology 2013; 37: 905-907.
Silbernagel G, Schöttker B,
Appelbaum S, Scharnagl H, Kleber ME, Grammer TB, Ritsch A, Mons U,
Holleczek B, Goliasch G, Niessner A, Boehm BO, Schnabel RB, Brenner H,
Blankenberg S, Landmesser U, März W.
High-density lipoprotein cholesterol, coronary artery disease and
cardiovascular mortality.
European Heart Journal 2013; 34: 3563-71.
Breitling LP, Olsen H, Müller
H, Schöttker B, Kliegel M, Brenner H.
Self- or physician-reported diabetes, glycemia markers, and cognitive
functioning in older adults in Germany.
American Journal of Geriatric Psychiatry 2013; S1064-7481(13)00282-0.
Wild B, Eckl A, Herzog W,
Niehoff D, Lechner S, Maatouk I, Schellberg D, Brenner H, Müller H, Löwe
B.
Assessing generalized anxiety disorder in elderly people by use of the
GAD-7 and GAD-2 scales - results of a validation study.
American Journal of Geriatric Psychiatry 2013; S1064-7481(13)00116-4.
Matsushita K, Ballew SH, Astor BC, de Jong PE,
Gansevoort RT, Hemmelgarn BR, Levey AS, Levin A, Wen C-P, Woodward M,
Coresh J, and for the CKD Prognosis Consortium*.
Cohort profile: the chronic kidney disease prognosis consortium.
International Journal of Epidemiology 2013; 42: 1660-1668.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller
H,
Schöttker B.
Yin L, Ordonez-Mena JM, Chen
T, Schöttker B, Arndt V, Brenner H.
Circulating 25-hydroxyvitamin D serum concentration and total cancer
incidence and mortality: a systematic review and meta-analysis.
Preventive Medicine 2013; 57: 753-764.
Schöttker B, Brenner H,
Koenig W, Müller H, Rothenbacher D.
Prognostic association of HbA1c and fasting plasma glucose with reduced
kidney function in subjects with and without diabetes mellitus. Results
from a population-based cohort study from Germany.
Preventive Medicine 2013; 57: 596-600.
Singh GM, Danaei G, Farzadfar F, Stevens GA,
Woodward M, Wormser D, Kaptoge S, Whitlock g, Qiao Q, Lewington s, Di
Angelantonio E, van der Hoorn S, Lawes CMM, Ali MK, Mozaffarian D, Ezzati
M, Global Burdon of Metabolic Risk Factors of Chronic Diseases
Collaborating Group, Asia-Pacific Cohort Studies Collaboration (APCSC),
Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in
Europe (DECODE), Emerging risk Factor Collaboration (ERFC)*, Prospective
Studies Collaboration (PSC).
The age-specific quantitative effects of metabolic risk factors on
cardiovascular diseases and diabetes: A pooled analysis.
PloS One 2013; 8:e65174.
*Authors on behalf of the ESTHER study: Brenner H, Schöttker B, Müller H,
Rothenbacher D.
Mons U, Schöttker B, Müller
H, Kliegel M, Brenner H.
History of lifetime smoking, smoking cessation and cognitive function in
the elderly population.
European Journal of Epidemiology 2013; 28:823-831.
Pesatori AC, Carugno M,
Consonni D, Hung RJ, Papadoupolos A, Landi M, Brenner H, Müller H, Harris
C, Duell E, Andrew A, McLaughlin J, Schwartz AG, Wenzlaff A, Stucker I.
Hormone use and risk for lung cancer: a pooled analysis from the
International Lung Cancer Consortium (ILCCO).
British Journal of Cancer 2013; 109:1954-1964.
Yu OH, Foulkes WD, Dastani Z,
Martin RM, Eeles R, PRACTICAL Consortium*, CRUK GWAS Investigators,
Richards JB.
An assessment of the shared allelic architecture between type II diabetes
and prostate cancer.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22:1473-1475.
*Author on behalf of the ESTHER study: Brenner H.
Gellert C, Schöttker B,
Müller H, Holleczek B, Brenner H.
Impact of smoking and quitting on cardiovascular outcomes and risk
advancement periods among older adults.
European Journal of Epidemiology 2013; 28:648-658.
Shlipak MG, Matsushita K, Ärnlöv J, Inker LA,
Katz R, Polkinghorne K, Rothenbacher D, Sarnak MJ, Astor BC, Coresh J,
Levey AS, Gansevoort RT, for the CKD Prognosis Consortium.*
Cystatin C versus creatinine for determining risk
based on kidney function.
New England Journal of Medicine 2013; 369:932-943.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Schöttker B,
Koenig W.
Kote-Jarai Z, Saunders EJ,
Leongamornlert DA, Tymrakiewicz M, Dadaev T, Jugurnauth-Little S,
Ross-Adams H, Al Olama AA, Benlloch S, Halim S, Russell R, Dunning AM,
Luccarini C, Dennis J, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG,
Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE,
Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock S,
Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F,
Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB,
Pharoah P, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau
SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J,
Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle A,
Clements JA, Teixeira MR, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ,
Morgan A, Dicks E, Baynes C, Conroy D, Bojesen SE, Kaaks R, Vincent D,
Bacot F, Tessier DC; COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative;
UK Genetic Prostate Cancer Study Collaborators/British Association of
Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators;
PRACTICAL Consortium, Easton DF, Eeles RA.
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one
of which associates with TERT expression.
Human Molecular Genetics 2013; 22: 2520-2528.
Ordóñez-Mena JM, Schöttker B,
Haug U, Müller H, Köhrle J, Schomburg L, Holleczek B, Brenner H.
Serum 25-hydroxyvitamin D and cancer risk in older adults. Results from a
large German prospective cohort study.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 905-916.
Zhang Y, Weck MN, Schöttker
B, Rothenbacher D, Brenner H.
Gastric parietal cell antibodies, Helicobacter pylori infection, and
chronic atrophic gastritis: Evidence from a large population-based study
in Germany.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 821-826.
Shen H, Fridley BL, Song H,
Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS, Tyrer J, Stram D, Larson
MC, Köbel M; PRACTICAL Consortium, Ziogas A, Zheng W, Yang HP, Wu AH,
Wozniak EL, Woo YL, Winterhoff B, Wik E, Whittemore AS, Wentzensen N,
Weber RP, Vitonis AF, Vincent D, Vierkant RA, Vergote I, Van Den Berg D,
Van Altena AM, Tworoger SS, Thompson PJ, Tessier DC, Terry KL, Teo SH,
Templeman C, Stram DO, Southey MC, Sieh W, Siddiqui N, Shvetsov YB, Shu
XO, Shridhar V, Wang-Gohrke S, Severi G, Schwaab I, Salvesen HB, Rzepecka
IK, Runnebaum IB, Rossing MA, Rodriguez-Rodriguez L, Risch HA, Renner SP,
Poole EM, Pike MC, Phelan CM, Pelttari LM, Pejovic T, Paul J, Orlow I,
Omar SZ, Olson SH, Odunsi K, Nickels S, Nevanlinna H, Ness RB, Narod SA,
Nakanishi T, Moysich KB, Monteiro AN, Moes-Sosnowska J, Modugno F, Menon
U, McLaughlin JR, McGuire V, Matsuo K, Adenan NA, Massuger LF, Lurie G,
Lundvall L, Lubiński J, Lissowska J, Levine DA, Leminen A, Lee AW,
Le ND, Lambrechts S, Lambrechts D, Kupryjanczyk J, Krakstad C, Konecny
GE, Kjaer SK, Kiemeney LA, Kelemen LE, Keeney GL, Karlan BY, Karevan R,
Kalli KR, Kajiyama H, Ji BT, Jensen A, Jakubowska A, Iversen E, Hosono S,
Høgdall CK, Høgdall E, Hoatlin M, Hillemanns P, Heitz F, Hein R, Harter
P, Halle MK, Hall P, Gronwald J, Gore M, Goodman MT, Giles GG,
Gentry-Maharaj A, Garcia-Closas M, Flanagan JM, Fasching PA, Ekici AB,
Edwards R, Eccles D, Easton DF, Dürst M, du Bois A, Dörk T, Doherty JA,
Despierre E, Dansonka-Mieszkowska A, Cybulski C, Cramer DW, Cook LS, Chen
X, Charbonneau B, Chang-Claude J, Campbell I, Butzow R, Bunker CH,
Brueggmann D, Brown R, Brooks-Wilson A, Brinton LA, Bogdanova N, Block
MS, Benjamin E, Beesley J, Beckmann MW, Bandera EV, Baglietto L, Bacot F,
Armasu SM, Antonenkova N, Anton-Culver H, Aben KK, Liang D, Wu X, Lu K,
Hildebrandt MA; Australian Ovarian Cancer Study Group; Australian Cancer
Study, Schildkraut JM, Sellers TA, Huntsman D, Berchuck A,
Chenevix-Trench G, Gayther SA, Pharoah PD, Laird PW, Goode EL, Pearce CL.
Epigenetic analysis leads to identification of HNF1B as a
subtype-specific susceptibility gene for ovarian cancer.
Nature Communications 2013; 4:1628. Doi: 10.1038/ncomms2629.
* Author on behalf of the ESTHER study: Brenner H.
Eeles RA, Olama AA, Benlloch
S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M,
Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC,
Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA,
Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter
DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker
J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles
SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL,
Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W,
Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY,
Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A,
Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy
M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart
RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge
T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL,
English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver
WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T,
Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder MA,
Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi
DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz
G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D,
Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo
P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC;
COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative;
Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer Study
Collaborators/British Association of Urological Surgeons' Section of
Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study
Collaborators; PRACTICAL (Prostate Cancer Association Group to
Investigate Cancer-Associated Alterations in the Genome) Consortium,
Kote-Jarai Z, Easton DF.
Identification of 23 new prostate cancer susceptibility loci using the
iCOGS custom genotyping array.
Nature Genetics 2013; 45: 385-391.
Bojesen SE, Pooley KA,
Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA,
Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y,
Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen
SF, Maranian MJ, Ghoussaini M, Ahmed S, Baynes C, Bolla MK, Wang Q,
Dennis J, McGuffog L, Barrowdale D, Lee A, Healey S, Lush M, Tessier DC,
Vincent D, Bacot F; Australian Cancer Study; Australian Ovarian Cancer
Study; Kathleen Cuningham Foundation Consortium for Research into
Familial Breast Cancer (kConFab); Gene Environment Interaction and Breast
Cancer (GENICA); Swedish Breast Cancer Study (SWE-BRCA); Hereditary
Breast and Ovarian Cancer Research Group Netherlands (HEBON);
Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE);
Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO),
Vergote I, Lambrechts S, Despierre E, Risch HA, González-Neira A, Rossing
MA, Pita G, Doherty JA, Alvarez N, Larson MC, Fridley BL, Schoof N,
Chang-Claude J, Cicek MS, Peto J, Kalli KR, Broeks A, Armasu SM, Schmidt
MK, Braaf LM, Winterhoff B, Nevanlinna H, Konecny GE, Lambrechts D, Rogmann
L, Guénel P, Teoman A, Milne RL, Garcia JJ, Cox A, Shridhar V, Burwinkel
B, Marme F, Hein R, Sawyer EJ, Haiman CA, Wang-Gohrke S, Andrulis IL,
Moysich KB, Hopper JL, Odunsi K, Lindblom A, Giles GG, Brenner H, Simard
J, Lurie G, Fasching PA, Carney ME, Radice P, Wilkens LR, Swerdlow A,
Goodman MT, Brauch H, Garcia-Closas M, Hillemanns P, Winqvist R, Dürst M,
Devilee P, Runnebaum I, Jakubowska A, Lubinski J, Mannermaa A, Butzow R,
Bogdanova NV, Dörk T, Pelttari LM, Zheng W, Leminen A, Anton-Culver H, Bunker
CH, Kristensen V, Ness RB, Muir K, Edwards R, Meindl A, Heitz F, Matsuo
K, du Bois A, Wu AH, Harter P, Teo SH, Schwaab I, Shu XO, Blot W, Hosono
S, Kang D, Nakanishi T, Hartman M, Yatabe Y, Hamann U, Karlan BY,
Sangrajrang S, Kjaer SK, Gaborieau V, Jensen A, Eccles D, Høgdall E, Shen
CY, Brown J, Woo YL, Shah M, Azmi MA, Luben R, Omar SZ, Czene K, Vierkant
RA, Nordestgaard BG, Flyger H, Vachon C, Olson JE, Wang X, Levine DA,
Rudolph A, Weber RP, Flesch-Janys D, Iversen E, Nickels S, Schildkraut
JM, Silva Idos S, Cramer DW, Gibson L, Terry KL, Fletcher O, Vitonis AF,
van der Schoot CE, Poole EM, Hogervorst FB, Tworoger SS, Liu J, Bandera
EV, Li J, Olson SH, Humphreys K, Orlow I, Blomqvist C,
Rodriguez-Rodriguez L, Aittomäki K, Salvesen HB, Muranen TA, Wik E,
Brouwers B, Krakstad C, Wauters E, Halle MK, Wildiers H, Kiemeney LA,
Mulot C, Aben KK, Laurent-Puig P, Altena AM, Truong T, Massuger LF,
Benitez J, Pejovic T, Perez JI, Hoatlin M, Zamora MP, Cook LS,
Balasubramanian SP, Kelemen LE, Schneeweiss A, Le ND, Sohn C,
Brooks-Wilson A, Tomlinson I, Kerin MJ, Miller N, Cybulski C, Henderson
BE, Menkiszak J, Schumacher F, Wentzensen N, Le Marchand L, Yang HP,
Mulligan AM, Glendon G, Engelholm SA, Knight JA, Høgdall CK, Apicella C,
Gore M, Tsimiklis H, Song H, Southey MC, Jager A, den Ouweland AM, Brown
R, Martens JW, Flanagan JM, Kriege M, Paul J, Margolin S, Siddiqui N,
Severi G, Whittemore AS, Baglietto L, McGuire V, Stegmaier C, Sieh W,
Müller H, Arndt V, Labrèche F, Gao YT, Goldberg MS, Yang G, Dumont M, McLaughlin
JR, Hartmann A, Ekici AB, Beckmann MW, Phelan CM, Lux MP, Permuth-Wey J,
Peissel B, Sellers TA, Ficarazzi F, Barile M, Ziogas A, Ashworth A,
Gentry-Maharaj A, Jones M, Ramus SJ, Orr N, Menon U, Pearce CL, Brüning
T, Pike MC, Ko YD, Lissowska J, Figueroa J, Kupryjanczyk J, Chanock SJ,
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Bidzinski M, Kauppila S, Hollestelle A, Seynaeve C, Tollenaar RA, Durda
K, Jaworska K, Hartikainen JM, Kosma VM, Kataja V, Antonenkova NN, Long
J, Shrubsole M, Deming-Halverson S, Lophatananon A, Siriwanarangsan P,
Stewart-Brown S, Ditsch N, Lichtner P, Schmutzler RK, Ito H, Iwata H,
Tajima K, Tseng CC, Stram DO, van den Berg D, Yip CH, Ikram MK, Teh YC,
Cai H, Lu W, Signorello LB, Cai Q, Noh DY, Yoo KY, Miao H, Iau PT, Teo
YY, McKay J, Shapiro C, Ademuyiwa F, Fountzilas G, Hsiung CN, Yu JC, Hou
MF, Healey CS, Luccarini C, Peock S, Stoppa-Lyonnet D, Peterlongo P,
Rebbeck TR, Piedmonte M, Singer CF, Friedman E, Thomassen M, Offit K,
Hansen TV, Neuhausen SL, Szabo CI, Blanco I, Garber J, Narod SA, Weitzel
JN, Montagna M, Olah E, Godwin AK, Yannoukakos D, Goldgar DE, Caldes T,
Imyanitov EN, Tihomirova L, Arun BK, Campbell I, Mensenkamp AR, van
Asperen CJ, van Roozendaal KE, Meijers-Heijboer H, Collée JM, Oosterwijk
JC, Hooning MJ, Rookus MA, van der Luijt RB, Os TA, Evans DG, Frost D,
Fineberg E, Barwell J, Walker L, Kennedy MJ, Platte R, Davidson R, Ellis
SD, Cole T, Bressac-de Paillerets B, Buecher B, Damiola F, Faivre L,
Frenay M, Sinilnikova OM, Caron O, Giraud S, Mazoyer S, Bonadona V,
Caux-Moncoutier V, Toloczko-Grabarek A, Gronwald J, Byrski T, Spurdle AB,
Bonanni B, Zaffaroni D, Giannini G, Bernard L, Dolcetti R, Manoukian S,
Arnold N, Engel C, Deissler H, Rhiem K, Niederacher D, Plendl H, Sutter
C, Wappenschmidt B, Borg A, Melin B, Rantala J, Soller M, Nathanson KL,
Domchek SM, Rodriguez GC, Salani R, Kaulich DG, Tea MK, Paluch SS,
Laitman Y, Skytte AB, Kruse TA, Jensen UB, Robson M, Gerdes AM, Ejlertsen
B, Foretova L, Savage SA, Lester J, Soucy P, Kuchenbaecker KB, Olswold C,
Cunningham JM, Slager S, Pankratz VS, Dicks E, Lakhani SR, Couch FJ, Hall
P, Monteiro AN, Gayther SA, Pharoah PD, Reddel RR, Goode EL, Greene MH,
Easton DF, Berchuck A, Antoniou AC, Chenevix-Trench G, Dunning AM.
Multiple independent variants at the TERT locus are associated with
telomere length and risks of breast and ovarian cancer.
Nature Genetics 2013; 45: 371-384.
Michailidou K, Hall P,
Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK,
Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C,
Rahman N; Breast and Ovarian Cancer Susceptibility Collaboration,
Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen
TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer
H, Adank M; Hereditary Breast and Ovarian Cancer Research Group
Netherlands (HEBON), van der Luijt RB, Hein R, Dahmen N, Beckman L,
Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Hopper JL, Southey
MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock
SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA,
Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J,
Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C,
Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph
A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen
T, Broeks A, Veer LJ, van der Schoot CE, Guénel P, Truong T, Laurent-Puig
P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP,
Perez JI, Pita G, Alonso MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer
EJ, Tomlinson I, Kerin MJ, Miller N, Henderson BE, Schumacher F, Le
Marchand L, Andrulis IL, Knight JA, Glendon G, Mulligan AM; kConFab
Investigators; Australian Ovarian Cancer Study Group, Lindblom A,
Margolin S, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Bui
QM, Stone J, Dite GS, Apicella C, Tsimiklis H, Giles GG, Severi G,
Baglietto L, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H,
Müller H, Arndt V, Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M,
Figueroa J, Lissowska J, Brinton L, Goldberg MS, Labrèche F, Dumont M,
Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U,
Brüning T; GENICA (Gene Environment Interaction and Breast Cancer in
Germany) Network, Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee
P, Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J,
Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM,
Bogdanova NV, Antonenkova NN, Dörk T, Kristensen VN, Anton-Culver H,
Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo K,
Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Shu
XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK, Hartman M,
Miao H, Lim WY, Sng JH, Muir K, Lophatananon A, Stewart-Brown S,
Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL, Sangrajrang S,
Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zheng W,
Deming-Halverson S, Shrubsole M, Long J, Simard J, Garcia-Closas M,
Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J, Easton DF.
Large-scale genotyping identifies 41 new loci associated with breast
cancer risk.
Nature Genetics 2013; 45: 353-361.
French JD, Ghoussaini M,
Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ,
O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley
J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D,
González-Neira A, Alonso MR, Herrero D, Tessier DC, Vincent D, Bacot F,
Luccarini C, Baynes C, Conroy D, Dennis J, Bolla MK, Wang Q, Hopper JL,
Southey MC, Schmidt MK, Broeks A, Verhoef S, Cornelissen S, Muir K,
Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Loehberg
CR, Ekici AB, Beckmann MW, Peto J, dos Santos Silva I, Johnson N, Aitken
Z, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A,
Sohn C, Burwinkel B, Guénel P, Truong T, Laurent-Puig P, Menegaux F,
Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Zamora MP,
Arias Perez JI, Benitez J, Anton-Culver H, Brenner H, Müller H, Arndt V,
Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Engel C, Brauch H,
Hamann U, Justenhoven C; GENICA Network, Aaltonen K, Heikkilä P,
Aittomäki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Sueta A, Bogdanova
NV, Antonenkova NN, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja
V, Kosma VM, Hartikainen JM; kConFab Investigators, Wu AH, Tseng CC, Van
Den Berg D, Stram DO, Lambrechts D, Peeters S, Smeets A, Floris G,
Chang-Claude J, Rudolph A, Nickels S, Flesch-Janys D, Radice P,
Peterlongo P, Bonanni B, Sardella D, Couch FJ, Wang X, Pankratz VS, Lee
A, Giles GG, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher
F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip
CH, Ng CH, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S,
Shrubsole M, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M,
Andrulis IL, Knight JA, Glendon G, Mulligan AM, Devilee P, Seynaeve C,
García-Closas M, Figueroa J, Chanock SJ, Lissowska J, Czene K, Klevebring
D, Schoof N, Hooning MJ, Martens JW, Collée JM, Tilanus-Linthorst M, Hall
P, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cox A,
Balasubramanian SP, Blot W, Signorello LB, Cai Q, Pharoah PD, Healey CS,
Shah M, Pooley KA, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Sng JH, Sim
X, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S,
Gaborieau V, McKay J, Toland AE, Ambrosone CB, Yannoukakos D, Godwin AK,
Shen CY, Hsiung CN, Wu PE, Chen ST, Swerdlow A, Ashworth A, Orr N,
Schoemaker MJ, Ponder BA, Nevanlinna H, Brown MA, Chenevix-Trench G,
Easton DF, Dunning AM.
Functional variants at the 11q13 risk locus for breast cancer regulate
Cyclin D1 expression through long-range enhancers.
American Journal of Human Genetics 2013; 92: 489-503.
Nickels S, Truong T, Hein R,
Stevens K, Buck K, Behrens S, Eilber U, Schmidt M, Häberle L, Vrieling A,
Gaudet M, Figueroa J, Schoof N, Spurdle AB, Rudolph A, Fasching PA,
Hopper JL, Makalic E, Schmidt DF, Southey MC, Beckmann MW, Ekici AB,
Fletcher O, Gibson L, Silva Idos S, Peto J, Humphreys MK, Wang J,
Cordina-Duverger E, Menegaux F, Nordestgaard BG, Bojesen SE, Lanng C,
Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Müller H,
Arndt V, Stegmaier C, Brauch H, Brüning T, Harth V; Genica Network,
Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab; AOCS Management
Group, Lambrechts D, Smeets D, Neven P, Paridaens R, Flesch-Janys D, Obi
N, Wang-Gohrke S, Couch FJ, Olson JE, Vachon CM, Giles GG, Severi G,
Baglietto L, Offit K, John EM, Miron A, Andrulis IL, Knight JA, Glendon
G, Mulligan AM, Chanock SJ, Lissowska J, Liu J, Cox A, Cramp H, Connley
D, Balasubramanian S, Dunning AM, Shah M, Trentham-Dietz A, Newcomb P,
Titus L, Egan K, Cahoon EK, Rajaraman P, Sigurdson AJ, Doody MM, Guénel
P, Pharoah PD, Schmidt MK, Hall P, Easton DF, Garcia-Closas M, Milne RL,
Chang-Claude J.
Evidence of gene-environment interactions between common breast cancer
susceptibility loci and established environmental risk factors.
PLoS Genetics 2013; 9: e1003284.
Schöttker B, Herder C,
Rothenbacher D, Perna L, Müller H, Brenner H.
Serum 25-hydroxyvitamin D levels and incident diabetes mellitus type 2. A
competing risk analysis in a large population-based cohort of older
adults.
European Journal of Epidemiology 2013; 28: 267-275.
Schöttker B, Haug U,
Schomburg L, Köhrle J, Perna L, Müller H, Holleczek B, Brenner H.
Strong associations of 25-hydroxyvitamin D levels with all-cause,
cardiovascular, cancer and respiratory disease mortality in a large
cohort study.
The American Journal of Clinical Nutrition 2013; 97: 782-793.
Perna L, Butterbach K, Haug
U, Schöttker B, Müller H, Arndt V, Holleczek B, Burwinkel B, Brenner H.
Vitamin D receptor genotype rs731236 (Taq1) and breast cancer prognosis.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 437-442.
Nitsch D, Grams M, Sang Y, Black C, Cirillo M,
Djurdjev O, Iseki K, Jassal SK, Kimm H, Kronenberg F, Øien CM, Levey AS,
Levin A, Woodward M, Hemmelgarn BR, for the CKD Prognosis Consortium.*
Do the associations of eGFR and albuminuria with
mortality and renal failure differ by gender? A meta-analysis from a
global consortium.
British Medical Journal 2013; 346:f324.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H,
Müller H,
Schöttker B.
Amin Al Olama A, Kote-Jarai
Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G,
Neal DE, Hamdy FC, Donovan JL, Hunter DJ, Henderson BE, Thun MJ, Gaziano
M, Giovannucci EL, Siddiq A, Travis RC, Cox DG, Canzian F, Riboli E, Key
TJ, Andriole G, Albanes D, Hayes RB, Schleutker J, Auvinen A, Tammela TL,
Weischer M, Stanford JL, Ostrander EA, Cybulski C, Lubinski J, Thibodeau
SN, Schaid DJ, Sorensen KD, Batra J, Clements JA, Chambers S, Aitken J,
Gardiner RA, Maier C, Vogel W, Dörk T, Brenner H, Habuchi T, Ingles S,
John EM, Dickinson JL, Cannon-Albright L, Teixeira MR, Kaneva R, Zhang
HW, Lu YJ, Park JY, Cooney KA, Muir KR, Leongamornlert DA, Saunders E,
Tymrakiewicz M, Mahmud N, Guy M, Govindasami K, O'Brien LT, Wilkinson RA,
Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A,
Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A,
Dudderidge T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL,
English D, Virtamo J, Le Marchand L, Campa D, Kaaks R, Lindstrom S, Diver
WR, Gapstur S, Yeager M, Cox A, Stern MC, Corral R, Aly M, Isaacs W,
Adolfsson J, Xu J, Zheng SL, Wahlfors T, Taari K, Kujala P, Klarskov P,
Nordestgaard BG, Røder MA, Frikke-Schmidt R, Bojesen SE, FitzGerald LM,
Kolb S, Kwon EM, Karyadi DM, Orntoft TF, Borre M, Rinckleb A, Luedeke M,
Herkommer K, Meyer A, Serth J, Marthick JR, Patterson B, Wokolorczyk D,
Spurdle A, Lose F, McDonnell SK, Joshi AD, Shahabi A, Pinto P, Santos J,
Ray A, Sellers TA, Lin HY, Stephenson RA, Teerlink C, Muller H, Rothenbacher
D, Tsuchiya N, Narita S, Cao GW, Slavov C, Mitev V; UK Genetic Prostate
Cancer Study Collaborators/British Association of Urological Surgeons'
Section of Oncology; UK ProtecT Study Collaborators; Australian Prostate
Cancer Bioresource; PRACTICAL Consortium, Chanock S, Gronberg H, Haiman
CA, Kraft P, Easton DF, Eeles RA.
A meta-analysis of genome-wide association studies to identify prostate
cancer susceptibility loci associated with aggressive and non-aggressive
disease.
Human
Molecular Genetics 2013; 22: 408-415.
Schöttker B, Herder C, Rothenbacher D, Roden M, Kolb H, Müller H,
Brenner H.
Proinflammatory cytokines,
adiponectin and increased risk of primary cardiovascular events in
patients with diabetes and renal dysfunction: results from the ESTHER
study.
Diabetes Care 2013; 36: 1703-1711.
Garcia-Closas M, Couch FJ,
Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli
E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching
PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles
GG, Cox A, Hopper JL, Bolla MK, Wang Q, Dennis J, Dicks E, Howat WJ,
Schoof N, Bojesen SE, Lambrechts D, Broeks A, Andrulis IL, Guénel P,
Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H,
Mannermaa A, Hamann U, Meindl A, Lindblom A, Zheng W, Devillee P,
Goldberg MS, Lubinski J, Kristensen V, Swerdlow A, Anton-Culver H, Dörk
T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu XO, Blot W, Kang D,
Hartman M, Sangrajrang S, Shen CY, Southey MC, Park DJ, Hammet F, Stone
J, Veer LJ, Rutgers EJ, Lophatananon A, Stewart-Brown S, Siriwanarangsan
P, Peto J, Schrauder MG, Ekici AB, Beckmann MW, Dos Santos Silva I,
Johnson N, Warren H, Tomlinson I, Kerin MJ, Miller N, Marme F,
Schneeweiss A, Sohn C, Truong T, Laurent-Puig P, Kerbrat P, Nordestgaard
BG, Nielsen SF, Flyger H, Milne RL, Perez JI, Menéndez P, Müller H, Arndt
V, Stegmaier C, Lichtner P, Lochmann M, Justenhoven C, Ko YD; Gene
ENvironmental Interaction and breast CAncer (GENICA) Network, Muranen TA,
Aittomäki K, Blomqvist C, Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y,
Antonenkova NN, Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine
R; kConFab Investigators, Tseng CC, Berg DV, Stram DO, Neven P, Dieudonné
AS, Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel
B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L, McLean
C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV, Labrèche
F, Dumont M, Yip CH, Taib NA, Cheng CY, Shrubsole M, Long J, Pylkäs K, Jukkola-Vuorinen
A, Kauppila S, Knight JA, Glendon G, Mulligan AM, Tollenaar RA, Seynaeve
CM, Kriege M, Hooning MJ, van den Ouweland AM, van Deurzen CH, Lu W, Gao
YT, Cai H, Balasubramanian SP, Cross SS, Reed MW, Signorello L, Cai Q,
Shah M, Miao H, Chan CW, Chia KS, Jakubowska A, Jaworska K, Durda K,
Hsiung CN, Wu PE, Yu JC, Ashworth A, Jones M, Tessier DC, González-Neira
A, Pita G, Alonso MR, Vincent D, Bacot F, Ambrosone CB, Bandera EV, John
EM, Chen GK, Hu JJ, Rodriguez-Gil JL, Bernstein L, Press MF, Ziegler RG,
Millikan RM, Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q,
Tsimiklis H, Makalic E, Schmidt D, Bui M, Gibson L, Müller-Myhsok B,
Schmutzler RK, Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto
A, Liu J, Turnbull C; Familial Breast Cancer Study (FBCS), Rahman N,
Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F; Australian Breast
Cancer Tissue Bank (ABCTB) Investigators, Olswold C, Slager S, Pilarski
R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ,
Rauh C, Lux MP, Jud SM, Bruning T, Weaver J, Sharma P, Pathak H, Tapper
W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R,
Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R,
Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg CD,
Hoover RN, Lissowska J, Figueroa JD, Chasman DI, Gaudet MM, Diver WR,
Willett WC, Hunter DJ, Simard J, Benitez J, Dunning AM, Sherman ME,
Chenevix-Trench G, Chanock SJ, Hall P, Pharoah PD, Vachon C, Easton DF,
Haiman CA, Kraft P.
Genome-wide association studies identify four ER-negative specific breast
cancer risk loci.
Nature
Genetics 2013; 45: 392-398.
Schöttker B, Müller H, Rothenbacher D, Brenner H.
Fasting plasma glucose and HbA1c in
cardiovascular risk prediction: a sex-specific comparison in individuals
without diabetes mellitus.
Diabetologia 2013; 56: 92-100.
Gellert C, Schöttker B,
Holleczek B, Stegmaier C, Müller H, Brenner H.
Using rate advancement periods for communicating the benefits of quitting
to older smokers.
Tobacco
Control 2013; 22: 227-230.
Perna L, Felix J, Breitling
LP, Haug U, Raum E, Burwinkel B, Schöttker B, Brenner H.
Genetic variations in the vitamin D
binding protein and season specific serum levels of 25-hydroxyvitamin D
among older adults.
Epidemiology 2013; 24: 104-109.
2012
Breitling LP, Perna L, Müller H, Raum E, Kliegel M, Brenner H.
Vitamin D and cognitive functioning in the elderly population in Germany.
Experimental Gerontology 2012; 47: 122-127.
Chuang SC, Jenab M, Heck JE,
Bosetti C, Talamini R, Matsuo K, Castellsague X, Franceschi S, Herrero R,
Winn DM, Vecchia CL, Morgenstern H, Zhang ZF, Levi F, Maso LD, Kelsey K,
McClean MD, Vaughan T, Lazarus P, Muscat J, Ramroth H, Chen C, Schwartz
SM, Eluf-Neto J, Hayes RB, Purdue M, Boccia S, Cadoni G, Zaridze D,
Koifman S, Curado MP, Ahrens W, Benhamou S, Matos E, Lagiou P,
Szeszenia-Dabrowska N, Olshan AF, Fernandez L, Menezes A, Agudo A, Daudt
AW, Merletti F, Macfarlane GJ, Kjaerheim K, Mates D, Holcatova I, Schantz
S, Yu GP, Simonato L, Brenner H, Mueller H, Conway DI, Thomson P,
Fabianova E, Znaor A, Rudnai P, Healy CM, Ferro G, Brennan P, Boffetta P,
Hashibe M.
Diet and the risk of head and neck cancer: a pooled analysis in the
INHANCE consortium.
Cancer Causes and Control 2012; 23: 69-88.
Schöttker B, Adamu MA, Weck
MN, Müller H, Brenner H.
Helicobacter pylori infection, chronic atrophic gastritis and major
cardiovascular events: a population-based cohort study.
Atherosclerosis 2012; 220: 569-574.
Maatouk I, Wild B, Wesche D,
Herzog W, Raum E, Müller H, Rothenbacher D, Stegmaier C, Schellberg D,
Brenner H.
Temporal predictors of health-related quality of life in elderly people
with diabetes: results of a German cohort study.
PLoS One 2012; 7: e31088.
Stott-Miller M, Chen C,
Chuang S-C, Lee YC, Boccia S, Brenner H, Cadoni G, Dal Maso L, La Vecchia
C, Lazarus P, Levi F, Matsuo K, Morgenstern H, Muller H, Muscat J, Olshan
AF, Purdue MP, Serraino D, Vaughan TL, Zhang Z-F, Boffetta P, Hashibe M,
Schwartz SM.
History of diabetes and risk of head and neck cancer:a pooled analysis
from the International Head and Neck Cancer Epidemiology (INHANCE)
Consortium.
Cancer Epidemiology Biomarkers & Prevention 2012; 21: 294-304.
Frank B, Weck MN, Müller H,
Klopp N, Illig T, Raum E, Brenner H.
Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with
the risk of chronic atrophic gastritis.
European Journal of Cancer 2012; 48: 114-120.
Ghoussaini M, Fletcher O,
Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang J, Humphreys
MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K,
Johnson N, Orr N, dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H,
Uitterlinden AG, HEBON, Hall P, Czene K, Irwanto A, Liu J,Nevanlinna H,
Aittomäki K, Blomqvist C, Meindl A, Schmutzler RK, Müller-Myhsok B,
Chang-Claude J, Hein R, Nickels S, Flesch-Janys D, Tsimiklis H, Makalic
E, Schmidt D, Bui M, Hopper JJ, Apicella C, Park DJ, Southey M, Broeks A,
Verhoef S, Hogervorst FBL, Fasching PA, Sawyer E, Tomlinson I, Kerin M,
Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T,
Cordina-Duverger E, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF,
Flyger H, Milne RL, Alonso R, González-Neira A, Benítez J, Anton-Culver
H, Ziogas A, Bernstein L, Clarke Dur C, Brenner H, Müller H, Arndt V,
Stegmaier C, FBCS, Justenhoven C, Brauch H, Pesch B, The GENICA Network,
Wang-Gohrke S, Eilber U, Dörk T, Schürmann P, Bremer M, Hillemanns P,
Bogdanova NV, Antonenkova NN, Rogov YI, Karstens JH, Bermisheva M,
Prokofieva D, Khusnutdinova E, Lindblom A, Margolin S, Mannermaa A,
Kataja V, Kosma V-M, Hartikainen J, Lambrechts D, Yesilyurt BT, Floris G,
Leunen K, Manoukian S, Bonanni B, Fortuzzi S, Peterlongo P, Radice P,
Peterlongo P, Manoukian S, Barile M, Couch FJ, Wang X, Stevens K, Lee A,
Giles GG, Baglietto L, Severi G, McLean C, Grenaker Alnæs G, Kristensen
V, Børrensen-Dale A-L, John EM, Miron A, Winqvist R, Pylkäs K,
Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Glendon G, Mulligan AM,
Devilee P, van Asperen CJ, Tollenaar RAEM, Seynaeve C, Figueroa JD,
Garcia-Closas M, Brinton L, Lissowska J, Hooning MJ, Hollestelle A,
Oldenburg RA, van den Ouweland AMW, Cox A, Reed MWR, Shah M, Jakubowska
A, Lubinski J, Jaworska K, Durda K, Jones M, Schoemaker M, Ashworth A,
Swerdlow A, Beesley J, Chen X, kConFab Investigators, Australian Ovarian
Cancer Study Group, Muir KR, Lophatananon A, Rattanamongkongul S,
Chaiwerawattana A, Kang D, Yoo K-Y, Noh D-Y, Shen C-Y, Yu J-C, Wu P-E,
Hsiung C-N, Perkins A, Swann R, Velentzis L, Eccles DM, Tapper WJ, Gerty
SM, Graham NJ, Ponder BA, Chenevix-Trench G, Pharoah PDP, Lathrop M,
Dunning AM, Rahman N, Peto J, Easton DF.
Genome-wide association analysis identifies three new breast cancer
susceptibility loci.
Nature Genetics 2012; 44: 312-318.
Schöttker B, Herder C, Müller
H, Brenner H, Rothenbacher D.
RE: Original Article - Clinical utility of creatinine and cystatin C
based definition of renal function for risk prediction of primary
cardiovascular events in patients with diabetes.
Diabetes Care 2012; 35: 879-886.
Wild B, Herzog W, Schellberg
D, Lechner S, Niehoff D, Brenner H, Rothenbacher D, Stegmaier C, Raum E.
Association between the prevalence of depression and age in a large
representative German sample of people aged 53 to 80.
International Journal of Geriatric Psychiatry 2012; 27: 375-381.
Wild B, Herzog W, Lechner S,
Niehoff D, Brenner H, Müller H, Rothenbacher D, Stegmaier C, Raum E.
Gender Specific Temporal and Cross-Sectional Associations between
BMI-class and Symptoms of Depression in the Elderly.
Journal of Psychosomatic Research 2012; 72: 376-382.
Stevens KN, Fredericksen Z,
Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D,
Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D,
Sinn HP, Wang-Gohrke S, Nickels S, Brauch H, Ko YD, Fischer HP, Network
TG, Schmutzler RK, Meindl A, Bartram CR, Schott S, Engel C, Godwin AK,
Weaver J, Pathak HB, Sharma P, Brenner H, Müller H, Arndt V, Stegmaier C,
Miron P, Yannoukakos D, Stavropoulou A, Fountzilas G, Gogas HJ, Swann R,
Dwek M, Perkins KA, Milne RL, Benítez J, Zamora MP, Ignacio Arias Pérez
J, Bojesen SE, Nielsen SF, Nordestgaard BG, Flyger H, Guénel P, Truong T,
Menegaux F, Cordina-Duverger E, Burwinkel B, Marmé F, Schneeweiss A, Sohn
C, Sawyer E, Tomlinson I, Kerin MJ, Peto J, Johnson N, Fletcher O, Dos
Santos Silva I, Fasching PA, Beckmann MW, Hartmann A, Ekici AB,
Lophatananon A, Muir K, Puttawibul P, Wiangnon S, Schmidt MK, Broeks A,
Braaf LM, Rosenberg EH, Hopper JL, Apicella C, Park DJ, Southey MC,
Swerdlow AJ, Ashworth A, Orr N, Schoemaker MJ, Anton-Culver H, Ziogas A,
Bernstein L, Clarke Dur C, Shen CY, Yu JC, Hsu HM, Hsiung CN, Hamann U,
Dünnebier T, Rüdiger T, Ulrich Ulmer H, Pharoah PD, Dunning AM, Humphreys
MK, Wang Q, Cox A, Cross SS, Reed MW, Hall P, Czene K, Ambrosone CB,
Ademuyiwa F, Hwang H, Eccles DM, Garcia-Closas M, Figueroa JD, Sherman
ME, Lissowska J, Devilee P, Seynaeve C, Tollenaar RA, Hooning MJ,
Andrulis IL, Knight JA, Glendon G, Mulligan AM, Winqvist R, Pylkäs K,
Jukkola-Vuorinen A, Grip M, John EM, Miron A, Grenaker Alnaes G,
Kristensen V, Borresen-Dale AL, Giles GG, Baglietto L, McLean CA, Severi
G, Kosel ML, Pankratz VS, Slager S, Olson JE, Radice P, Peterlongo P,
Manoukian S, Barile M, Lambrechts D, Hatse S, Dieudonne AS, Christiaens
MR, Chenevix-Trench G, Investigators K, Group A, Beesley J, Chen X,
Mannermaa A, Kosma VM, Hartikainen JM, Soini Y, Easton DF, Couch FJ.
19p13.1 is a triple negative-specific breast cancer susceptibility locus.
Cancer Research 2012; 72: 1795-1803.
Schöttker B, Adamu M, Weck
MN, Brenner H.
Helicobacter pylori infection is strongly associated with gastric and
duodenal ulcers in a large prospective study.
Clinical Gastroenterology and Hepatology 2012; 10: 487-493.
Matsushita K, Mahmoodi BK,
Woodward M, Emberson JR, Jafar TH, Jee SH, Polkinghorne KR, Shankar A,
Smith DH, Tonelli M, Warnock DG, Wen C-P, Coresh J, Gansevoort RT,
Hemmelgarn BR, Levey AS, for the Chronic Kidney Disease Prognosis
Consortium. (Investigators/ Collaborators for the ESTHER study in the
Chronic Kidney Disease Prognosis Consortium: Rothenbacher D, Brenner H,
Müller H, Schöttker B).
Comparison of risk prediction using the CKD-EPI equation and the MDRD
Study equation for estimated glomerular filtration rate.
JAMA 2012; 307: 1941-1951.
Lambrechts D, Truong T,
Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, Apicella C ,
Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien R, Sawyer E,
Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez JIA, Benítez
J, Hamann U, Ko YD, Brüning T, The GENICA Network, Chang-Claude J, Eilber
U, Hein R, Nickels S, Flesch-Janys D, Wang-Gohrke S, John EM, Miron A,
Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Chenevix-Trench G,
Beesley J, Chen X, kConFab Investigators, Australian Ovarian Cancer Study
Group, Menegaux F, Cordina-Duverger E, Shen C-Y, Yu J-C, Wu P-E, Hou M-F,
Andrulis IL, Selander T, Glendon G, Mulligan AM, Anton-Culver H, Ziogas
A, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Jones M,
Orr N, Ashworth A, Swerdlow A, Severi G, Baglietto L, Giles G, Southey M,
Marmé F, Schneeweiss A, Sohn C, Burwinkel B, Yesilyurt BT, Neven P,
Paridaens R, Wildiers H, Brenner H, Müller H, Arndt V, Stegmaier C,
Meindl A, Schott S, Bartram CR, Schmutzler RK, Cox A, Brock IW, Elliott
G, Cross SS, Fasching PA, Schulz-Wendtland R, Ekici AB, Beckmann MW,
Fletcher O, Johnson N, dos Santos Silva I, Peto J, Nevanlinna H, Muranen
TA, Aittomäki K, Blomqvist C, Dörk T, Schürmann P, Bremer M, Hillemanns
P, Bogdanova NV, Antonenkova NN, Rogov YI, Karstens JH, Khusnutdinova E,
Bermisheva M, Prokofieva D, Gancev S, Jakubowska A, Lubinski J, Jaworska
K, Durda K, Nordestgaard BG, Bojesen SE, Lanng C, Mannermaa A, Kataja V,
Kosma V-M, Hartikainen JM, Radice P, Peterlongo P, Manoukian S, Bernard
L, Couch FJ, Olson JE, Wang X, Fredericksen Z, Grenaker Alnæs G,
Kristensen V, Børresen-Dale A-L, Devilee P, Tollenaar RAEM, Seynaeve CM,
Hooning MJ, García-Closas M, Chanock SJ, Lissowska J, Sherman ME, Hall P,
Liu J, Czene K, Kang D, Yoo K-Y, Noh D-Y, Lindblom A, Margolin S, Dunning
AM, Pharoah PDP, Easton DF, Guénel P, Brauch H.
11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast
Cancer.
Human Mutation 2012; 33: 1123-1132.
Krämer HU, Müller H,
Stegmaier C, Rothenbacher D, Raum E, Brenner H.
Type 2 diabetes mellitus and gender-specific risk for colorectal
neoplasia.
European Journal of Epidemiology 2012; 27: 341-347.
Coté ML, Liu M, Bonassi S,
Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Aben
KK, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, Brenner H,
Duell EJ, Fabianova E, Field JK, Foretova L, Friis S, Harris CC,
Holcatova I, Hong YC, Isla D, Janout V, Kiemeney LA, Kiyohara C, Lan Q,
Lazarus P, Lissowska J, Le Marchand L, Mates D, Matsuo K, Mayordomo JI,
McLaughlin JR, Morgenstern H, Müller H, Orlow I, Park BJ, Pinchev M, Raji
OY, Rennert HS, Rudnai P, Seow A, Stucker I, Szeszenia-Dabrowska N, Dawn
Teare M, Tjønneland A, Ugolini D, van der Heijden HF, Wichmann E, Wiencke
JK, Woll PJ, Yang P, Zaridze D, Zhang ZF, Etzel CJ, Hung RJ.
Increased risk of lung cancer in individuals with a family history of the
disease: A pooled analysis from the International Lung Cancer Consortium.
European Journal of Cancer 2012; 48: 1957-1968.
Maatouk I, Wild B, Herzog W,
Wesche D, Schellberg D, Schöttker B, Müller H, Rothenbacher D, Stegmaier
C, Brenner H.
Longitudinal predictors of health-related quality of life in middle-aged
and older adults with hypertension: results of a population based study.
Journal of Hypertension 2012; 30: 1364-1372.
The Emerging Risk Factors Collaboration.*
C-reactive protein, fibrinogen, and
cardiovascular disease prediction.
New England Journal of Medicine 2012; 367: 1310-1320.
* Participating investigators on behalf of the ESTHER Study: Brenner H
(member of writing committee), Schöttker B, Müller H, Rothenbacher D).
Perna L, Haug U, Schöttker B,
Müller H, Raum E, Jansen EHJM, Brenner H.
Public health implications of standardized 25-hydroxyvitamin D levels: a
decrease in the prevalence of vitamin D deficiency among older women in Germany.
Preventive Medicine 2012; 55: 228-232.
The Emerging Risk Factors Collaboration.*
Adult height and the risk of cause-specific death
and vascular morbidity in 1 million adults. International Journal of
Epidemiology 2012; 41: 1419-1433. *Participating Investigators on behalf
of the ESTHER Study: Brenner H, Schöttker B, Müller H, Rothenbacher D.
Warren H, Dudbridge F, Fletcher O, Orr N, Johnson N, Hopper JL, Apicella
C, Southey MC, Mahmoodi M, Schmidt MK, Broeks A, Cornelissen S, Braaf LM,
Muir K, Lophatananon A, Chaiwerawattana A, Wiangnon S, Fasching PA,
Beckmann MW, Ekici AB, Schulz-Wendtland R, Sawyer EJ, Tomlinson I, Kerin
MJ, Burwinkel B, Marme F, Schneeweiss A, Sohn C, Guenel P, Truong T,
Laurent-Puig P, Mulot C, Bojesen SE, Nielsen SF, Flyger H, Nordestgaard
BG, Milne RL, Benitez J, Ignacio Arias Perez J, Zamora MP, Anton-Culver
H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Muller H, Arndt V,
Langheinz A, Meindl A, Golatta M, Bartram CR, Schmutzler RK, Brauch H,
Justenhoven C, Bruning T, Chang-Claude J, Wang-Gohrke S, Eilber U, Dork
T, Schurmann P, Bremer M, Hillemanns P, Nevanlinna H, Muranen TA,
Aittomäki K, Blomqvist C, Bogdanova N, Antonenkova N, Rogov Y, Bermisheva
M, Prokofyeva D, Zinnatullina G, Khusnutdinova E, Lindblom A, Margolin S,
Mannermaa A, Kosma VM, Hartikainen JM, Kataja V, Chenevix-Trench G,
Beesley J, Chen X, Lambrechts D, Smeets A, Paridaens R, Weltens C,
Flesch-Janys D, Buck K, Behrens S, Peterlongo P, Bernard L, Manoukian S,
Radice P, Couch FJ, Vachon CM, Wang X, Olsen JE, Giles GG, Baglietto L,
McLean CA, Severi G, John EM, Miron A, Winqvist R, Pylkäs K,
Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Mulligan AM,
Weerasooriya N, Devilee P, Tollenaar RA, Martens JW, Seynaeve CM, Hooning
MJ, Hollestelle A, Jager A, Tilanus-Linthorst MM, Hall P, Czene K,
Jianjun L, Jingmei L, Cox A, Cross SS, Brock IW, Reed MW, Pharoah PD,
Blows FM, Dunning AM, Ghoussaini M, Ashworth A, Swerdlow A, Jones M,
Schoemaker MJ, Easton DF, Humphreys MK, Wang Q, Peto J, Dos Santos Silva
I.
9q31.2-rs865686 as a susceptibility locus for
estrogen receptor-positive breast cancer: evidence from the Breast Cancer
Association Consortium.
Cancer Epidemiology, Biomarkers & Prevention
2012; 21: 1783-1791.
Schöttker B, Jansen EHJM, Haug U, Schomberg L, Köhrle J, Brenner H.
Standardization of misleading immunoassay based
25-hydroxyvitamin D levels with liquid chromatography tandem-mass
spectrometry in a large cohort study.
PLoS One 2012; 7: e48774.
Saum K-U, Müller H, Stegmaier C, Hauer K, Raum E, Brenner H.
Development and evaluation of a modification of
the Fried frailty criteria using population-independent cutpoints.
Journal of the American Geriatrics Society 2012;
60: 2110-2115.
Fox CS, Matsushita K, Woodward M, Bilo HJG, Chalmers J, Lambers Heerspink
HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA,
Yamagishi K, Coresh J, de Jong PE, Wen C-P, Nelson RG, on behalf of the
CKD Prognosis Consortium (Investigators/Collaborators for the ESTHER
study in the Chronic Kidney Disease Prognosis Consortium: Rothenbacher D,
Brenner H, Müller H, Schöttker B).
Associations of kidney disease measures with
mortality and end-stage renal disease in individuals with and without
diabetes: a meta-analysis.
Lancet 2012; 380: 1662-1673.
Mahmoodi BK, Matsushita K, Woodward M, Blankestijn PJ, Cirillo M, Ohkubo
T, Rossing P, Sarnak MJ, Stengel B, Yamagishi K, Yamashita K, Zhang L,
Coresh J, de Jong PE, MD2; Astor BC, for the Chronic Kidney Disease
Prognosis Consortium (Investigators/Collaborators for the ESTHER study in
the Chronic Kidney Disease Prognosis Consortium: Rothenbacher D, Brenner
H, Müller H, Schöttker B).
Associations of kidney disease measures with
mortality and end-stage renal disease in individuals with and without
hypertension: a meta-analysis.
Lancet 2012; 380; 1649-1661.
Breitling LP, Müller H, Stegmaier C, Kliegel M, Brenner H.
Association of prion protein with cognitive
functioning in humans.
Experimental Gerontology 2012; 47: 919-924.
Hallan SI, Matsushita K, Sang Y, Mahmoodi BK, Black C, Ishani A,
Kleefstra N, Naimark D, Roderick P, Tonelli M, Wetzels JFM, Astor BC,
Gansevoort RT, Levin A, Wen C-P, Coresh J for the Chronic Kidney Disease
Prognosis Consortium.*
Age and association of kidney measures with mortality and end-stage renal
disease.
JAMA 2012; 308: 2349-2360.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Raum
E,
Koenig W.
2011
Adamu MA, Weck MN, Rothenbacher D, Brenner H.
Incidence and risk factors for the development of chronic atrophic
gastritis: five year follow-up of a population based cohort study.
International Journal of Cancer 2011; 128: 1652-1658.
Wild B, Lechner S, Herzog W,
Maatouk I, Raum E, Müller H, Brenner H, Slaets J, Huyse F, Söllner W.
Reliable integrative assessment of health care needs in elderly persons -
the INTERMED for the Elderly (IM-E).
Journal of Psychosomatic Research 2011; 70: 169-178.
Yang R, Dick M, Marme F,
Schneeweiss A, Langheinz A, Hemminki K, Sutter C, Bugert P, Wappenschmidt
B, Varon R, Schott S, Weber BHF, Niederacher D, Arnold N, Meindl A,
Bartram CR, Schmutzler RK, Müller H, Arndt V, Brenner H, Sohn C,
Burwinkel B.
Genetic variants within miR-126 and miR-335 are not associated with
breast cancer risk.
Breast Cancer Research and Treatment 2011; 127: 549-554.
The Emerging Risk Factors
Collaboration.*
Diabetes mellitus, fasting glucose, and risk of cause-specific mortality.
New England Journal of Medicine 2011; 364: 829-841.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Breitling LP, Yang R, Korn B,
Burwinkel B, Brenner H.
Tobacco smoking-related differential DNA methylation: 27k discovery and
replication.
American Journal of Human Genetics 2011; 88: 450-457.
Herder C, Schoettker B, Rothenbacher D, Roden M, Kolb H, Müller H,
Brenner H.
Interleukin-6 in the prediction of
primary cardiovascular events in diabetes patients: results from the
ESTHER study.
Atherosclerosis 2011; 216: 244-247.
Kote-Jarai Z, Al Olama AA,
Giles GG, Severi G, Schleutker J, Weischer M, Canzian F, Riboli E, Key T,
Gronberg H, Hunter DJ, Kraft P, J Thun MJ, Ingles S, Chanock S, Albanes
D, Hayes RB, Neal DE, Hamdy FC, Donovan JL, Pharoah P, Schumacher F,
Henderson BE, Stanford JL, Ostrander EA, Dalsgaard Sorensen K, Dörk T,
Andriole G, Dickinson JL, Cybulski C, Lubinski J, Spurdle A, Clements JA,
Chambers S, Aitken J, Gardiner F, Thibodeau SN, Schaid D, John EM, Maier
C, Vogel W, Cooney KA, Park JY, Cannon-Albright L, Brenner H, Habuchi T,
Zhang H-W, Lu Y-J, Kaneva R, Muir K, Benlloch S, Leongamornlert DA,
Saunders EJ, Tymrakiewicz M, Mahmud N, Guy M, O’Brien LT, Wilkinson RA,
Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A,
Huddart RA, Khoo VS, Parker CC, van As N, Woodhouse CJ, Thompson A,
Christmas T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL,
English D, Wahlfors T, Tammela TLJ, Klarskov P, Nordestgaard BG, Røder
MA, Tybjærg-Hansen A, Bojesen SE, Travis R, Campa D, Kaaks R, Wiklund F,
Aly M, Lindstrom S, Diver WR, Gapstur S , Stern MC, Corral R, Virtamo J,
Cox A, Haiman CA, Le Marchand L, FitzGerald L, Kolb S, Kwon EM, Karyadi
DM, Falck Orntoft T, Borre M, Meyer A, Serth J, Yeager M, Berndt SI,
Marthick JR, Patterson B, Wokolorczyk D, Batra J, Lose F, McDonnell SK ,
Joshi AD, Shahabi A , Rinckleb AE, Ray A, Sellers TA, Lin H-Y, Stephenson
RA, Farnham J, Müller H, Rothenbacher D, Tsuchiya N, Narita S, Cao G-W ,
Slavov C, Mitev V, The UK Genetic Prostate Cancer Study
Collaborators/British Association of Urological Surgeons’ Section of
Oncology, The UK ProtecT Study Collaborators, The PRACTICAL Consortium,
Easton DF, Eeles RA.
Seven prostate cancer susceptibility loci identified by a multi-stage
genome-wide association study.
Nature Genetics 2011; 43: 785-791. doi:
10.1038/ng.882.
Breitling LP, Müller H, Illig
T, Rujescu D, Winterer G, Dahmen N, Nitz B, Raum E, Rothenbacher D,
Brenner H.
Dopamine-related genes and spontaneous smoking cessation in ever-heavy
smokers.
Pharmacogenomics 2011; 12: 1099-1106.
Nicolotti N, Chuang S-C,
Cadoni G, Arzani D, Petrelli L, Bosetti C, Brenner H, Hosono S, La
Vecchia C, Matsuo K, Müller H, Muscat J, Paludetti G, Ricciardi G,
Boffetta P,
Hashibe M, Boccia S.
Recreational physical activity and risk of head and neck cancer: a pooled
analysis within the International Head and Neck Cancer Epidemiology
(INHANCE) Consortium.
European Journal of Epidemiology 2011; 26: 619-628.
Milne RL, Goode EL,
Garcia-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N,
Zamora MP, Ignacio Arias Perez J, Benítez J, Dork T, Schurmann P,
Karstens JH, Hillemanns P, Cox A, Brock IW, Elliott G, Cross SS, Seal S,
Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC, Huang CS, Hou MF,
Nordestgaard BG, Bojesen SE, Lanng C, Grenaker Alnaes G, Kristensen V,
Borresen-Dale AL, Hopper JL, Dite GS, Apicella C, Southey MC, Lambrechts
D, Yesilyurt BT, Floris G, Leunen K, Sangrajrang S, Gaborieau V, Brennan
P, McKay J, Chang-Claude J, Wang-Gohrke S, Radice P, Peterlongo P,
Manoukian S, Barile M, Giles GG, Baglietto L, John EM, Miron A, Chanock
SJ, Lissowska J, Sherman ME, Figueroa JD, Bogdanova NV, Antonenkova NN,
Zalutsky IV, Rogov YI, Fasching PA, Bayer CM, Ekici AB, Beckmann MW,
Brenner H, Muller H, Arndt V, Stegmaier C, Andrulis IL, Knight JA,
Glendon G, Mulligan AM, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Meindl
A, Heil J, Bartram CR, Schmutzler RK, Thomas GD, Hoover RN, Fletcher O,
Gibson LJ, Dos Santos Silva I, Peto J, Nickels S, Flesch-Janys D,
Anton-Culver H, Ziogas A, Sawyer E, Tomlinson I, Kerin M, Miller N,
Schmidt MK, Broeks A, Vant Veer LJ, Tollenaar RA, Pharoah PD, Dunning AM,
Pooley KA, Marmee F, Schneeweiss A, Sohn C, Burwinkel B, Jakubowska A,
Lubinski J, Jaworska K, Durda K, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter
DJ, Hankinson SE, Kraft P, Lindström S, Chen X, Beesley J, Hamann U,
Harth V, Justenhoven C, Winqvist R, Pylkas K, Jukkola-Vuorinen A, Grip M,
Hooning M, Hollestelle A, Oldenburg RA, Tilanus-Linthorst M,
Khusnutdinova E, Bermisheva M, Prokofieva D, Farahtdinova A, Olson JE,
Wang X, Humphreys MK, Wang Q, Chenevix-Trench G, Easton DF.
Confirmation of 5p12 as a susceptibility locus for
progesterone-receptor-positive, lower grade breast cancer.
Cancer Epidemiology, Biomarkers & Prevention 2011; 20: 2222-2231.
Frank B, Müller H, Weck MN,
Klopp N, Illig T, Raum E, Brenner H.
DNA repair gene polymorphisms and risk of chronic atrophic gastritis: a
case-control study.
BMC Cancer 2011; 11: 440.
Figueroa JD, Garcia-Closas M,
Humphreys M, Platte R, Hopper JL, Southey MC, Apicella C, Hammet F,
Schmidt MK, Broeks A, Tollenaar RA, Van 't Veer LJ, Fasching PA, Beckmann
MW, Ekici AB, Strick R, Peto J, Dos Santos Silva I, Fletcher O, Johnson
N, Sawyer E, Tomlinson I, Kerin M, Burwinkel B, Marme F, Schneeweiss A,
Sohn C, Bojesen S, Flyger H, Nordestgaard BG, Benítez J, Milne R, Arias
JI, Zamora MP, Brenner H, Müller H, Arndt V, Rahman N, Turnbull C, Seal
S, Renwick A, Brauch H, Justenhoven C, Brüningv T; The GENICA network,
Chang-Claude J, Hein R, Wang-Gohrke S, Dörk T, Schürmann P, Bremer M,
Hillemanns P, Nevanlinna H, Heikkinen T, Aittomäki K, Blomqvist C, Bogdanova
N, Antonenkovav N, Rogov Y, Karstens JH, Bermisheva M, Prokofyeva D,
Gancev SH, .Khusnutdinova E, Lindblom A, Margolin S, Chenevix-Trench G,
Beesley J, Chen X; kConFab AOCS Management Group, Mannermaa A, Kosma VM,
Soini Y, Kataja V, Lambrechts D, Yesilyurt BT, Chrisiaens MR, Peeters S,
Radice P, Peterlongo P, Manoukian S, Barile M, Couch F, Lee AM, Diasio R,
Wang X, Giles GG, Severi G, Baglietto L, Maclean C, Offit K, Robson M,
Joseph V, Gaudet M, John EM, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip
M, Andrulis I, Knight JA, Mulligan AM, O'Malley FP, Brinton L, Sherman M,
Lissowska J, Chanock S, Hooning M, Martens JW, van den Ouweland AM,
Collée JM, Hall P, Czene K, Cox A, Brock IW, Reed MW, Cross SS, Pharoah
P, Dunning AM, Kang D, Yoo KY, Noh DY, Ahn SH, Jakubowska A, Lubinski J,
Jaworska K, Durda K, Sangrajrang S, Gaborieau V, .Brennan P, McKay J,
Shen CY, Ding SL, Hsu HM, Yu JC, Anton-Culver H, Ziogas A, .Ashworth A,
Swerdlow A, Jones M, Orr N, Trentham-Dietz A, Egan K, Newcomb P,
Titus-.Ernstoff L, Easton D, Spurdle AB.
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with
breast cancer risk and heterogeneity by tumor subtype: findings from the
Breast Cancer Association Consortium.
Human Molecular Genetics 2011; 20: 4693-4706.
Schöttker B, Raum E, Rothenbacher D, Müller H,
Brenner H.
Prognostic value of haemoglobin A1c and fasting plasma glucose for
incident diabetes and implications for screening.
European Journal of Epidemiology 2011; 26: 779-787.
2010
The Emerging Risk Factors Collaboration.*
C-reactive protein concentration and the risk of coronary heart disease,
stroke and mortality.
Lancet 2010; 375: 132-140.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H.
Alcohol consumption, serum
gamma-glutamyltransferase and Helicobacter pylori infection in a
population-based study among 9733 older adults.
Annals of Epidemiology 2010; 20: 122-128.
Gao L, Weck MN, Raum E,
Stegmaier C, Rothenbacher D, Brenner H.
Sibship size, Helicobacter pylori infection and chronic atrophic
gastritis: a population-based study among 9444 older adults from Germany.
International Journal of Epidemiology 2010; 39: 129-134.
Mobascher A, Rujescu D,
Mittelstraß K, Giegling I, Lamina C, Nitz B, Brenner H, Fehr C, Breitling
LP, Gallinat J, Rothenbacher D, Raum E, Müller H, Ruppert A, Hartmann AM,
Möller HJ, Gal A, Gieger C, Wichmann HE, Illig T, Dahmen N, Winterer G.
Association of a variant in the muscarinic acetylcholine receptor 2 gene
(CHRM2) with nicotine addiction.
American Journal of Medical Genetics Part B - Neuropsychiatric Genetics
2010; 153B: 684-690.
Breitling LP, Müller H, Raum
E, Rothenbacher D, Brenner H.
Low-to-moderate alcohol consumption and smoking cessation rates:
retrospective analysis of 4576 elderly ever-smokers.
Drug Alcohol Depend 2010; 108: 122-129.
Triglyceride Coronary Disease
Genetics Consortium and Emerging Risk Factors Collaboration.*
Triglyceride-mediated pathways and coronary disease: collaborative
analysis of 101 studies.
Lancet 2010; 375: 1634-1639.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Chronic Kidney Disease Prognosis Consortium.*
Association of estimated glomerular filtration rate and albuminuria with
all-cause and cardiovascular mortality in general population cohorts: a
collaborative meta-analysis.
Lancet 2010; 375: 2073-2081.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Raum
E,
Koenig W.
Zhang Q-L, Brenner H, Koenig
W, Rothenbacher D.
Prognostic value of chronic kidney disease in patients with coronary
heart disease: role of estimating equations.
Atherosclerosis 2010; 211: 342-347.
The Emerging Risk Factors
Collaboration.*
Diabetes mellitus, fasting blood glucose concentration, and risk of
vascular disease: a collaborative meta-analysis of 102 prospective
studies.
Lancet 2010; 375: 2215-2222.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Truong T, Hung RJ, Amos CI,
Wu X, Bickeboeller H, Rosenberger A, Sauter W, Illig T, Wichmann HE,
Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, Wrensch M,
Hansen H, Kelsey KT, Matsuo K, Tajima K, Schwartz A, Wenzlaff A, Seow A,
Ying C, Staratschek-Jox A, Nuernberg P, Stoelben E, Wolf J, Lazarus P,
Muscat JE, Gallagher C, Zienolddiny S, Haugen A, van der Heijden HFM,
Kiemeney LA, Isla D, Mayordomo JI, Rafnar T, Stefansson K, Zhang ZF,
Chang SC, Kim JH, Hong YC, Duell EJ, Andrew AS, Lejbkowicz F, Rennert G,
Mueller H, Brenner H, Le Marchand L, Benhamou S, Bouchardy C, Teare MD,
Xue X, McLaughlin J, Liu G, McKay JD, Brennan P, Spitz M.
Replication of lung cancer susceptibility loci at chromosome 15q25, 5p15,
and 6p21: A pooled analysis from the International Lung Cancer
Consortium.
Journal of the National Cancer Institute 2010; 102: 959-971.
Gao L, Weck MN, Rothenbacher
D, Brenner H.
Body mass index, chronic atrophic gastritis and heartburn: a
population-based study among 8936 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2010; 32: 296-302.
Gao L, Weck MN, Nieters A,
Brenner H.
Grb2-associated binder 1 (Gab1) genetic polymorphism, Helicobacter pylori
infection and chronic atrophic gastritis among older adults from Germany.
Molecular Carcinogenesis 2010; 49: 869-873.
Breitling LP, Wolf M, Müller
H, Raum E, Kliegel M, Brenner H.
Large-scale application of a telephone-based test of cognitive
functioning in older adults.
Dementia and Geriatric Cognitive Disorders 2010; 30: 309-316.
Thompson S, Kaptoge S, White
I, Wood A, Perry P, Danesh J and The Emerging Risk Factors
Collaboration.*
Statistical methods for the time-to-event analysis of individual
participant data from multiple epidemiological studies.
International Journal of Epidemiology 2010; 39: 1345-1359.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Winterer G, Mittelstraß K, Giegling I, Lamina C,
Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat J,
Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller H-J, Gieger
C, Wichmann H-E, Illig T, Dahmen N, Rujescu D.
Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4
cluster are associated with cognitive performance.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
2010; 153B: 1448-1458.
2009
Zhang Q-L, Koenig W, Raum E, Stegmaier C, Brenner H, Rothenbacher D.
Epidemiology of chronic kidney disease: results from a population of
older adults in Germany.
Preventive Medicine 2009; 48: 122-127.
Breitling LP, Raum E, Müller
H, Rothenbacher D, Brenner H.
Synergism between smoking and alcohol consumption with respect to serum
gamma-glutamyltransferase.
Hepatology 2009; 49: 802-808.
Gao L, Weck MN, Michel A,
Pawlita M, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15
Helicobacter pylori proteins measured by multiple serology.
Cancer Research 2009; 69: 2973-2980.
Breitling LP, Dahmen N,
Mittelstraß K, Illig T, Rujescu D, Raum E, Winterer G, Brenner H.
Smoking cessation and variations in nicotinic acetylcholine receptor
subunits a-5, a-3 and b-4 genes.
Biological Psychiatry 2009; 65: 691-695.
Müller H, Raum E,
Rothenbacher D, Stegmaier C, Brenner H.
Association of diabetes and body mass index with levels of
prostate-specific antigen: Implications for correction of
prostate-specific antigen cut-off values?
Cancer Epidemiology, Biomarkers & Prevention 2009; 18: 1350-1356.
Weck MN, Gao L, Brenner H.
Helicobacter pylori infection and chronic atrophic gastritis:
associations according to severity of disease.
Epidemiology 2009; 20: 569-574.
Widschwendter M,
Lichtenberg-Frate H, Hasenbrink G, Schwarzer S, Dawnay A, Lam A, Menon U,
Apostolidou S, Raum E, Stegmaier C, Jacobs IJ, Brenner H.
Serum oestrogen receptor alpha- and beta-bioactivity are independently
associated with breast cancer - a proof of principle study.
British Journal of Cancer 2009; 101: 160-165.
The Emerging Risk Factors Collaboration.*
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke
and nonvascular mortality. Individual data analysis of 126,634
participants from 36 prospective studies. JAMA 2009; 302: 412-423.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
Gao L, Michel A, Weck MN, Arndt
V, Pawlita M, Brenner H.
Helicobacter pylori infection and gastric cancer risk: evaluation of 15
Helicobacter pylori proteins determined by novel multiplex serology.
Cancer Research 2009; 69: 6164-6160.
Breitling LP, Dahmen N, Illig
T, Rujescu D, Nitz B, Raum E, Winterer G, Rothenbacher D, Brenner H.
Variants in COMT and spontaneous smoking cessation: retrospective cohort
analysis of 925 cessation events.
Pharmacogenetics & Genomics 2009; 19: 657-659.
Breitling LP, Dahmen N,
Mittelstraß K, Rujescu D, Gallinat J, Fehr C, Giegling I, Lamina C, Illig
T, Müller H, Raum E, Rothenbacher D, Wichmann HE, Brenner H, Winterer G.
Association of nicotinic acetylcholine receptor subunit alpha-4
polymorphisms with nicotine dependence in 5500 Germans.
The Pharmacogenomics Journal 2009; 9: 219-224.
Gao L, Weck MN, Nieters A,
Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15
Helicobacter pylori proteins measured by multiple serology.
European Journal of Cancer; 69: 2973-2980.
Gao L, Weck MN, Stegmaier C, Rothenbacher D,
Brenner H.
Alcohol consumption and chronic atrophic
gastritis: population-based study among 9444 older adults from Germany.
International Journal of Cancer 2009;
125:2918-2922.
The Emerging Risk Factors Collaboration.*
Major lipids, apolipoproteins and risk of
vascular disease.
JAMA 2009; 302: 1993-2000.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.
2008
Raum E, Lietzau S, Stegmaier C, Brenner H., Rothenbacher D.
For the majority of patients with diabetes blood pressure and lipid
management is not in line with recommendations. Results from a large
population-based cohort in Germany.
Pharmacoepidemiology and Drug Safety 2008; 17: 485-494.
Widschwendter M, Apostolidou
S, Raum E, Rothenbacher D, Fiegl H, Menon U, Stegmaier C, Jacobs IJ,
Brenner H.
Epigenotyping in peripheral blood cell DNA and breast cancer risk: a
proof of principle study.
PloS ONE 2008; 3: e2656.
Müller H, Haug U, Rothenbacher D, Stegmaier C,
Brenner H.
Evaluation of serum and urine MRP-14 as marker for early detection of
prostate cancer.
Journal of Urology 2008; 180: 1309-1313.
2007
Haug U, Hillebrand T, Bendzko P, Löw M, Rothenbacher D, Stegmaier C,
Brenner H.
Mutant-enriched PCR and allele-specific hybridization reaction to detect
K-ras-mutations in stool DNA: High prevalence in a large sample of older
adults.
Clinical Chemistry 2007; 53: 787-790.
Wolkewitz M, Rothenbacher D,
Löw M, Stegmaier C, Ziegler H, Radulescu M, Brenner H, Diepgen TL.
Lifetime prevalence of self-reported atopic diseases in a
population-based sample of elderly: results of the ESTHER-study.
British Journal of Dermatology 2007; 156: 693-697.
Haug U, Rothenbacher D, Wente
MN, Seiler CM, Stegmaier C, Brenner H.
Tumor M2-PK as a stool marker for colorectal cancer: comparative analysis
in a large sample of unselected older adults versus colorectal cancer
patients.
British Journal of Cancer 2007; 96: 1329-1334.
Raum E, Rothenbacher D,
Ziegler H, Brenner H.
Heavy physical activity – risk or protective factor for cardiovascular
disease? A life course perspective.
Annals of Epidemiology 2007; 17: 417-424.
Weck MN, Stegmaier C,
Rothenbacher D, Brenner H.
Epidemiology of chronic atrophic gastritis: population based study among
9,444 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2007; 26: 879-887.
Brenner H, Rothenbacher D,
Weck MN.
Epidemiologic findings on serologically defined chronic atrophic
gastritis strongly depend on the choice of the cutoff-value.
International Journal of Cancer 2007; 121: 2782-2786.
Raum E, Rothenbacher D, Löw M, Stegmaier C,
Ziegler H, Brenner H.
Changes of cardiovascular risk factors and their implications in
subsequent birth cohorts of older adults in Germany: a life course
approach.
European Journal of Cardiovascular Prevention and Rehabilitation 2007;
14: 809-814.
2006
Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The diagnosis of a smoking-related disease is a prominent trigger for
smoking cessation in a retrospective cohort study.
Journal of Clinical Epidemiology 2006; 59: 82-89.
Twardella D, Loew M,
Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The impact of body weight on smoking cessation in German adults.
Preventive Medicine 2006; 42: 109-113.
Wang H, Rothenbacher D, Löw M, Stegmaier C,
Brenner H, Diepgen TL.
Atopic diseases, immunoglobulin E and risk of cancer of the prostate,
breast, lung und colorectum.
International
Journal of Cancer 2006; 119: 695-701.
2004
Löw M, Stegmaier C, Ziegler H, Rothenbacher D, Brenner H.
Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und
optimierten Therapie chronischer Erkrankungen in der älteren Bevölkerung
(ESTHER-Studie).
Deutsche Medizinische Wochenschrift 2004; 129: 2643-2647.
Bergk V, Gasse C, Rothenbacher D, Loew M, Brenner H, Haefeli WE.
Drug interactions in primary care:
impact of a new algorithm on risk determination.
Clinical Pharmacology and Therapeutics 2004; 76: 85-96.
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