Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und optimierten THerapie chronischer ERkrankungen in der älteren Bevölkerung

 

 

 

 

 


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Publikationen

2017


Brenner H, Jansen L, Saum KU, Holleczek B, Schöttker B.

Vitamin D Supplementation Trials Aimed at Reducing Mortality Have Much Higher Power When Focusing on People with Low Serum 25-Hydroxyvitamin D Concentrations.

J Nutr. 2017 Jul;147(7):1325-1333. doi: 10.3945/jn.117.250191.

Epub 2017 May 24.


Bock JO, Hajek A, Brenner H, Saum KU, Matschinger H, Haefeli WE, Schöttker B, Quinzler R, Heider D, König HH.
A Longitudinal Investigation of Willingness to Pay for Health Insurance in Germany.
Health Serv Res. 2017 Jun;52(3):1099-1117. doi: 10.1111/1475-6773.12522.

Epub 2016 Jun 20.


Mayer T, Meid AD, Saum KU, Brenner H, Schöttker B, Seidling HM, Haefeli WE.

Comparison of Nine Instruments to Calculate Anticholinergic Load in a Large Cohort of Older Outpatients: Association with Cognitive and Functional Decline, Falls, and Use of Laxatives.

Am J Geriatr Psychiatry. 2017 May;25(5):531-540. doi: 10.1016/j.jagp.2017.01.009.

Epub 2017 Jan 23.


Heiss JA, Brenner H.

Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors.

Epigenomics. 2017 May;9(5):659-668. doi: 10.2217/epi-2016-0154.

Epub 2017 May 4.


Mons U, Müezzinler A, Schöttker B, Dieffenbach AK, Butterbach K, Schick M, Peasey A, De Vivo I, Trichopoulou A, Boffetta P, Brenner H.

Leukocyte Telomere Length and All-Cause, Cardiovascular Disease, and Cancer Mortality: Results From Individual-Participant-Data Meta-Analysis of 2 Large Prospective Cohort Studies.

Am J Epidemiol. 2017 Apr 28:1-10. doi: 10.1093/aje/kww210.

[Epub ahead of print]


Steele CJ, Schöttker B, Marshall AH, Kouvonen A, O'Doherty MG, Mons U, Saum KU, Boffetta P, Trichopoulou A, Brenner H, Kee F.

Education achievement and type 2 diabetes-what mediates the relationship in older adults? Data from the ESTHER study: a population-based cohort study.

BMJ Open. 2017 Apr 17;7(4):e013569. doi: 10.1136/bmjopen-2016-013569.


Zhang Y, Hapala J, Brenner H, Wagner W.

Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging.

Clin Epigenetics. 2017 Feb 2;9:9. doi: 10.1186/s13148-017-0315-9. eCollection 2017.


Hajek A, Bock JO, Brenner H, Saum KU, Matschinger H, Haefeli WE, Quinzler R, Heider D, König HH.

[Which Factors Affect Out-of-pocket Payments for Health Care Services Among Elderly Germans? Results of a Longitudinal Study].

Gesundheitswesen. 2017 Feb;79(2):e18-e25. doi: 10.1055/s-0035-1564247.

Epub 2015 Nov 9. German.


Saum KU, Schöttker B, Meid AD, Holleczek B, Haefeli WE, Hauer K, Brenner H.

Is Polypharmacy Associated with Frailty in Older People? Results From the ESTHER Cohort Study.

J Am Geriatr Soc. 2017 Feb;65(2):e27-e32. doi: 10.1111/jgs.14718.

Epub 2016 Dec 26.


Ordónez-Mena JM, Maalmi H, Schöttker B, Saum KU, Holleczek B, Wang TJ, Burwinkel B, Brenner H.
Genetic variants in the vitamin D pathway, 25(OH)D levels, and mortality in a large population-based cohort study.
J Clin Endocrinol Metab. 2017 Feb 1;102(2):470-477. doi: 10.1210/jc.2016-2468.

 


2016


Gao X, Mons U, Zhang Y, Breitling LP, Brenner H.
DNA methylation changes in response to active smoking exposure are associated with leukocyte telomere length among older adults.
Eur J Epidemiol. 2016 Dec;31(12):1231-1241. doi: 10.1007/s10654-016-0210-2.

Epub 2016 Nov 10.


Fuchs J, Scheidt-Nave C, Gaertner B, Dapp U, von Renteln-Kruse W, Saum KU, Thorand B, Strobl R, Grill E.
[Frailty in Germany: status and perspectives : Results from a workshop of the German Society for Epidemiology].
Z Gerontol Geriatr. 2016 Dec;49(8):734-742. Epub 2015 Dec 14. Review. German.


Breitling LP, Saum KU, Schöttker B, Holleczek B, Herth FJ, Brenner H.
Pneumonia in the Noninstitutionalized Older Population.
Dtsch Arztebl Int. 2016 Sep 16;113(37):607-614. doi: 10.3238/arztebl.2016.0607.


Gao X, Zhang Y, Breitling LP, Brenner H.
Tobacco smoking and methylation of genes related to lung cancer development.
Oncotarget. 2016 Sep 13;7(37):59017-59028. doi: 10.18632/oncotarget.10007.


Maatouk I, Herzog W, Böhlen F, Quinzler R, Löwe B, Saum KU, Brenner H, Wild B.
Association of hypertension with depression and generalized anxiety symptoms in a large population-based sample of older adults.
J Hypertens. 2016 Sep;34(9):1711-20. doi: 10.1097/HJH.0000000000001006.


Chen LS, Baker T, Hung RJ, Horton A, Culverhouse R, Hartz S, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Rosenberger A, Aben KK, Andrew AS, Chang SC, Saum KU, Dienemann H, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden EH, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Brüske I, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare MD, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Amos CI, Bierut LJ.
Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis.
EBioMedicine. 2016 Sep;11:219-226. doi: 10.1016/j.ebiom.2016.08.012.

Epub 2016 Aug 10.


Boehlen FH, Herzog W, Schellberg D, Maatouk I, Saum KU, Brenner H, Wild B.
Self-perceived coping resources of middle-aged and older adults - results of a large population-based study.
Aging Ment Health. 2016 Aug 29:1-7. doi: 10.1080/13607863.2016.1220918.

[Epub ahead of print]


Schmidt MK, Hogervorst F, van Hien R, Cornelissen S, Broeks A, Adank MA, Meijers H, Waisfisz Q, Hollestelle A, Schutte M, van den Ouweland A, Hooning M, Andrulis IL, Anton-Culver H, Antonenkova NN, Antoniou AC, Arndt V, Bermisheva M, Bogdanova NV, Bolla MK, Brauch H, Brenner H, Brüning T, Burwinkel B, Chang-Claude J, Chenevix-Trench G, Couch FJ, Cox A, Cross SS, Czene K, Dunning AM, Fasching PA, Figueroa J, Fletcher O, Flyger H, Galle E, García-Closas M, Giles GG, Haeberle L, Hall P, Hillemanns P, Hopper JL, Jakubowska A, John EM, Jones M, Khusnutdinova E, Knight JA, Kosma VM, Kristensen V, Lee A, Lindblom A, Lubinski J, Mannermaa A, Margolin S, Meindl A, Milne RL, Muranen TA, Newcomb PA, Offit K, Park-Simon TW, Peto J, Pharoah PD, Robson M, Rudolph A, Sawyer EJ, Schmutzler RK, Seynaeve C, Soens J, Southey MC, Spurdle AB, Surowy H, Swerdlow A, Tollenaar RA, Tomlinson I, Trentham-Dietz A, Vachon C, Wang Q, Whittemore AS, Ziogas A, van der Kolk L, Nevanlinna H, Dörk T, Bojesen S, Easton DF.
Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.
J Clin Oncol. 2016 Aug 10;34(23):2750-60. doi: 10.1200/JCO.2016.66.5844.

Epub 2016 Jun 6.


Gao X, Zhang Y, Breitling LP, Brenner H.
Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration.
Oncotarget. 2016 Jul 26;7(30):46878-46889. doi: 10.18632/oncotarget.9795.

NCD Risk Factor Collaboration (NCD-RisC).
A century of trends in adult human height.
Elife. 2016 Jul 26;5. pii: e13410. doi: 10.7554/eLife.13410.


Meid AD, Quinzler R, Groll A, Wild B, Saum KU, Schöttker B, Heider D, König HH, Brenner H, Haefeli WE.
Longitudinal evaluation of medication underuse in older outpatients and its association with quality of life.
Eur J Clin Pharmacol. 2016 Jul;72(7):877-85. doi: 10.1007/s00228-016-2047-8.

Epub 2016 Mar 29.


Lechner S, Herzog W, Boehlen F, Maatouk I, Saum KU, Brenner H, Wild B.
Control preferences in treatment decisions among older adults - Results of a large population-based study.
J Psychosom Res. 2016 Jul;86:28-33. doi: 10.1016/j.jpsychores.2016.05.004.

Epub 2016 May 11.


Brück K, Stel VS, Gambaro G, Hallan S, Völzke H, Ärnlöv J, Kastarinen M, Guessous I, Vinhas J, Stengel B, Brenner H, Chudek J, Romundstad S, Tomson C, Gonzalez AO, Bello AK, Ferrieres J, Palmieri L, Browne G, Capuano V, Van Biesen W, Zoccali C, Gansevoort R, Navis G, Rothenbacher D, Ferraro PM, Nitsch D, Wanner C, Jager KJ; European CKD Burden Consortium.
CKD Prevalence Varies across the European General Population.
J Am Soc Nephrol.
2016 Jul;27(7):2135-47. doi: 10.1681/ASN.2015050542.

Epub 2015 Dec 23.


Hajek A, Bock JO, Saum KU, Schöttker B, Brenner H, Heider D, König HH.
[Morbidity Differences by Health Insurance Status in Old Age].
Gesundheitswesen. 2016 Jun 28. [Epub ahead of print]


Perna L, Zhang Y, Mons U, Holleczek B, Saum KU, Brenner H.
Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort.
Clin Epigenetics. 2016 Jun 3;8:64. doi: 10.1186/s13148-016-0228-z. eCollection 2016.


O'Doherty MG, Cairns K, O'Neill V, Lamrock F, Jørgensen T, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kuulasmaa K, Boffetta P, Trichopoulou A, Kee F.
Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES).
Eur J Epidemiol. 2016 May;31(5):455-68. doi: 10.1007/s10654-015-0112-8.

Epub 2016 Jan 18.


Bock JO, König HH, Brenner H, Haefeli WE, Quinzler R, Matschinger H, Saum KU, Schöttker B, Heider D.
Associations of frailty with health care costs - results of the ESTHER cohort study.
BMC Health Serv Res. 2016 Apr 14;16(1):128. doi: 10.1186/s12913-016-1360-3.

Zhang Y, Florath I, Saum KU, Brenner H.
Self-reported smoking, serum cotinine, and blood DNA methylation.
Environ Res. 2016 Apr;146:395-403. doi: 10.1016/j.envres.2016.01.026.

Epub 2016 Jan 29.


NCD Risk Factor Collaboration (NCD-RisC).
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants.
Lancet. 2016 Apr 9;387(10027):1513-30. doi: 10.1016/S0140-6736(16)00618-8.

Epub 2016 Apr 6.


Ordóñez-Mena JM, Schöttker B, Mons U, Jenab M, Freisling H, Bueno-de-Mesquita B, O'Doherty MG, Scott A, Kee F, Stricker BH, Hofman A, de Keyser CE, Ruiter R, Söderberg S, Jousilahti P, Kuulasmaa K, Freedman ND, Wilsgaard T, de Groot LC, Kampman E, Håkansson N, Orsini N, Wolk A, Nilsson LM, Tjønneland A, Pająk A, Malyutina S, Kubínová R, Tamosiunas A, Bobak M, Katsoulis M, Orfanos P, Boffetta P, Trichopoulou A, Brenner H; Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES).
Quantification of the smoking-associated cancer risk with rate advancement periods: meta-analysis of individual participant data from cohorts of the CHANCES consortium.
BMC Med. 2016 Apr 5;14(1):62. doi: 10.1186/s12916-016-0607-5.


NCD Risk Factor Collaboration (NCD-RisC).
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants.
Lancet. 2016 Apr 2;387(10026):1377-96. doi: 10.1016/S0140-6736(16)30054-X.


Chen XZ, Schöttker B, Castro FA, Chen H, Zhang Y, Holleczek B, Brenner H.
Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic, pancreatic and gastric cancer: A ten-year follow-up of the ESTHER cohort study.
Oncotarget. 2016 Mar 29;7(13):17182-93. doi: 10.18632/oncotarget.7946.


Ordóñez-Mena JM, Schöttker B, Fedirko V, Jenab M, Olsen A, Halkjær J, Kampman E, de Groot L, Jansen E, Bueno-de-Mesquita HB, Peeters PH, Siganos G, Wilsgaard T, Perna L, Holleczek B, Pettersson-Kymmer U, Orfanos P, Trichopoulou A, Boffetta P, Brenner H.
Pre-diagnostic vitamin D concentrations and cancer risks in older individuals: an analysis of cohorts participating in the CHANCES consortium.
Eur J Epidemiol. 2016 Mar;31(3):311-23. doi: 10.1007/s10654-015-0040-7.

Epub 2015 May 15.


Bock JO, Heider D, Matschinger H, Brenner H, Saum KU, Haefeli WE, König HH.
Willingness to pay for health insurance among the elderly population in Germany.
Eur J Health Econ. 2016 Mar;17(2):149-58. doi: 10.1007/s10198-014-0663-8.

Epub 2014 Dec 20.


Breitling LP, Saum KU, Perna L, Schöttker B, Holleczek B, Brenner H.
Frailty is associated with the epigenetic clock but not with telomere length in a German cohort.
Clin Epigenetics. 2016 Feb 26;8:21. doi: 10.1186/s13148-016-0186-5. eCollection 2016.


Schöttker B, Rathmann W, Herder C, Thorand B, Wilsgaard T, Njølstad I, Siganos G, Mathiesen EB, Saum KU, Peasey A, Feskens E, Boffetta P, Trichopoulou A, Kuulasmaa K, Kee F, Brenner H; CHANCES group.
HbA1c levels in non-diabetic older adults - No J-shaped associations with primary cardiovascular events, cardiovascular and all-cause mortality after adjustment for confounders in a meta-analysis of individual participant data from six cohort studies.
BMC Med. 2016 Feb 11;14(1):26. doi: 10.1186/s12916-016-0570-1.


Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier C, Brenner H.
Body mass index and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort.
Exp Gerontol. 2016 Feb;74:1-8. doi: 10.1016/j.exger.2015.11.019.

Epub 2015 Nov 30.


Boehlen FH, Herzog W, Maatouk I, Saum KU, Brenner H, Wild B.
[Treatment preferences of elderly patients with mental disorders].
Z Gerontol Geriatr. 2016 Feb;49(2):120-5. doi: 10.1007/s00391-015-0908-x.

Epub 2015 Jun 2.


Schöttker B, Saum KU, Jansen EH, Holleczek B, Brenner H.
Associations of metabolic, inflammatory and oxidative stress markers with total morbidity and multi-morbidity in a large cohort of older German adults.
Age Ageing. 2016 Jan;45(1):127-35. doi: 10.1093/ageing/afv159.

Epub 2015 Nov 11.


Florath I, Butterbach K, Heiss J, Bewerunge-Hudler M, Zhang Y, Schöttker B, Brenner H.
Type 2 diabetes and leucocyte DNA methylation: an epigenome-wide association study in over 1,500 older adults.
Diabetologia. 2016 Jan;59(1):130-8. doi: 10.1007/s00125-015-3773-7.

Epub 2015 Oct 3.

 


2015


Schöttker B, Brenner H, Jansen EH, Gardiner J, Peasey A, Kubínová R, Pająk A, Topor-Madry R, Tamosiunas A, Saum KU, Holleczek B, Pikhart H, Bobak M.
Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data.
BMC Med. 2015 Dec 15;13:300. doi: 10.1186/s12916-015-0537-7.


Cheng TH, Thompson D, Painter J, O'Mara T, Gorman M, Martin L, Palles C, Jones A, Buchanan DD, Ko Win A, Hopper J, Jenkins M, Lindor NM, Newcomb PA, Gallinger S, Conti D, Schumacher F, Casey G, Giles GG, Pharoah P, Peto J, Cox A, Swerdlow A, Couch F, Cunningham JM, Goode EL, Winham SJ, Lambrechts D, Fasching P, Burwinkel B, Brenner H, Brauch H, Chang-Claude J, Salvesen HB, Kristensen V, Darabi H, Li J, Liu T, Lindblom A, Hall P, de Polanco ME, Sans M, Carracedo A, Castellvi-Bel S, Rojas-Martinez A, Aguiar Jnr S, Teixeira MR, Dunning AM, Dennis J, Otton G, Proietto T, Holliday E, Attia J, Ashton K, Scott RJ, McEvoy M, Dowdy SC, Fridley BL, Werner HM, Trovik J, Njolstad TS, Tham E, Mints M, Runnebaum I, Hillemanns P, Dörk T, Amant F, Schrauwen S, Hein A, Beckmann MW, Ekici A, Czene K, Meindl A, Bolla MK, Michailidou K, Tyrer JP, Wang Q, Ahmed S, Healey CS, Shah M, Annibali D, Depreeuw J, Al-Tassan NA, Harris R, Meyer BF, Whiffin N, Hosking FJ, Kinnersley B, Farrington SM, Timofeeva M, Tenesa A, Campbell H, Haile RW, Hodgson S, Carvajal-Carmona L, Cheadle JP, Easton D, Dunlop M, Houlston R, Spurdle A, Tomlinson I.
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.
Sci Rep. 2015 Dec 1;5:17369. doi: 10.1038/srep17369.


Bozorgmehr K, Maier W, Brenner H, Saum KU, Stock C, Miksch A, Holleczek B, Szecsenyi J, Razum O.
Social disparities in Disease Management Programmes for coronary heart disease in Germany: a cross-classified multilevel analysis.
J Epidemiol Community Health. 2015 Nov;69(11):1091-101. doi: 10.1136/jech-2014-204506. Epub 2015 Jun 16.


Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier C, Brenner H.
Smoking habits and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort.
Exp Gerontol. 2015 Oct;70:18-25. doi: 10.1016/j.exger.2015.07.002. Epub 2015 Aug 6.


Freigofas J, Seidling HM, Quinzler R, Schöttker B, Saum KU, Brenner H, Haefeli WE.
Characteristics of medication schedules used by elderly ambulatory patients.
Eur J Clin Pharmacol. 2015 Sep;71(9):1109-20. doi: 10.1007/s00228-015-1888-x. Epub 2015 Jun 24.


Schöttker B, Zhang Y, Heiss JA, Butterbach K, Jansen EH, Bewerunge-Hudler M, Saum KU, Holleczek B, Brenner H
Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood.
Genes Chromosomes Cancer. 2015 Sep;54(9):583-94. doi: 10.1002/gcc.22271. Epub 2015 Jul 14.


Boehlen F, Herzog W, Quinzler R, Haefeli WE, Maatouk I, Niehoff D, Saum KU, Brenner H, Wild B.

Loneliness in the elderly is associated with the use of psychotropic drugs.

Int J Geriatr Psychiatry. 2015 Sep;30(9):957-64. doi: 10.1002/gps.4246. Epub 2014 Dec 12.


Meid AD, Quinzler R, Freigofas J, Saum KU, Schöttker B, Holleczek B, Heider D, König HH, Brenner H, Haefeli WE.
Medication Underuse in Aging Outpatients with Cardiovascular Disease: Prevalence, Determinants, and Outcomes in a Prospective Cohort Study.
PLoS One. 2015 Aug 19;10(8):e0136339. doi: 10.1371/journal.pone.0136339. eCollection 2015.


Vart P, Bakker SJ, Schöttker B, de Zeeuw D, Rothenbacher D, Brenner H, Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U, Koenig W, Gansevoort RT.
Relevance of correction for drift and day-to-day variation in cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with independent replication in the ESTHER cohort.
Clin Chem Lab Med. 2015 Aug;53(9):1381-90. doi: 10.1515/cclm-2014-0894.


Benetou V, Orfanos P, Feskanich D, Michaëlsson K, Pettersson-Kymmer U, Ahmed LA, Peasey A, Wolk A, Brenner H, Bobak M, Wilsgaard T, Schöttker B, Saum KU, Bellavia A, Grodstein F, Klinaki E, Valanou E, Papatesta EM, Boffetta P, Trichopoulou A.
Education, marital status, and risk of hip fractures in older men and women: the CHANCES project.
Osteoporos Int. 2015 Jun;26(6):1733-46. doi: 10.1007/s00198-015-3054-9. Epub 2015 Mar 28.


Schöttker B, Brenner H.
Vitamin D as a Resilience Factor, Helpful for Survival of Potentially Fatal Conditions: A Hypothesis Emerging from Recent Findings of the ESTHER Cohort Study and the CHANCES Consortium.
Nutrients. 2015 May 6;7(5):3264-78. doi: 10.3390/nu7053264. Review.


Perna L, Wahl HW, Mons U, Saum KU, Holleczek B, Brenner H.

Cognitive impairment, all-cause and cause-specific mortality among non-demented older adults.

Age Ageing. 2015 May;44(3):445-51. doi: 10.1093/ageing/afu188. Epub 2014 Dec 2.


Saum KU, Dieffenbach AK, Jansen EH, Schöttker B, Holleczek B, Hauer K, Brenner H.
Association between Oxidative Stress and Frailty in an Elderly German Population: Results from the ESTHER Cohort Study.
Gerontology. 2015;61(5):407-15. doi: 10.1159/000380881. Epub 2015 Apr 24.


Emrich IE, Pickering JW, Schöttker B, Lennartz CS, Rogacev KS, Brenner H, Rothenbacher D, Holleczek B, Saum KU, Fliser D, Heine GH.
Comparison of the performance of 2 GFR estimating equations using creatinine and cystatin C to predict adverse outcomes in elderly individuals.
Am J Kidney Dis. 2015 Apr;65(4):636-8. doi: 10.1053/j.ajkd.2014.12.006. Epub 2015 Jan 23. No abstract available.


Schöttker B, Saum KU, Jansen EH, Boffetta P, Trichopoulou A, Holleczek B, Dieffenbach AK, Brenner H.

Oxidative Stress Markers and All-Cause Mortality at Older Age: A Population-Based Cohort Study.

J Gerontol A Biol Sci Med Sci. 2015 Apr;70(4):518-24. doi: 10.1093/gerona/glu111. Epub 2014 Jul 28.


Bozorgmehr K, San Sebastian M, Brenner H, Razum O, Maier W, Saum KU,
Holleczek B, Miksch A, Szecsenyi J.
Analysing horizontal equity in enrolment in Disease Management Programmes for coronary heart disease in Germany 2008-2010.
Int J Equity Health. 2015 Mar 10;14(1):28. doi: 10.1186/s12939-015-0155-1.


Painter JN, O'Mara TA, Batra J, Cheng T, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Kaufmann S, Hillman KM, Walpole C, Moya L, Pollock P, Jones A, Howarth K, Martin L, Gorman M, Hodgson S; National Study of Endometrial Cancer Genetics Group (NSECG); CHIBCHA Consortium, De Polanco MM, Sans M, Carracedo A, Castellvi-Bel S, Rojas-Martinez A, Santos E, Teixeira MR, Carvajal-Carmona L, Shu XO, Long J, Zheng W, Xiang YB; The Australian National Endometrial Cancer Study Group (ANECS), Montgomery GW, Webb PM, Scott RJ, McEvoy M, Attia J, Holliday E, Martin NG, Nyholt DR, Henders AK, Fasching PA, Hein A, Beckmann MW, Renner SP, Dörk T, Hillemanns P, Dürst M, Runnebaum I, Lambrechts D, Coenegrachts L, Schrauwen S, Amant F, Winterhoff B, Dowdy SC, Goode EL, Teoman A, Salvesen HB, Trovik J, Njolstad TS, Werner HM, Ashton K, Proietto T, Otton G, Tzortzatos G, Mints M, Tham E; RENDOCAS, Hall P, Czene K, Liu J, Li J, Hopper JL, Southey MC; Australian Ovarian Cancer Study (AOCS), Ekici AB, Ruebner M, Johnson N, Peto J, Burwinkel B, Marme F, Brenner H, Dieffenbach AK, Meindl A, Brauch H; The GENICA Network, Lindblom A, Depreeuw J, Moisse M, Chang-Claude J, Rudolph A, Couch FJ, Olson JE, Giles GG, Bruinsma F, Cunningham JM, Fridley BL, Børresen-Dale AL, Kristensen VN, Cox A, Swerdlow AJ, Orr N, Bolla MK, Wang Q, Weber RP, Chen Z, Shah M, French JD, Pharoah PD, Dunning AM, Tomlinson I, Easton DF, Edwards SL, Thompson DJ, Spurdle AB.

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.

Hum Mol Genet. 2015 Mar 1;24(5):1478-92. doi: 10.1093/hmg/ddu552. Epub 2014 Nov 6.

 


2014


O'Doherty MG, Jørgensen T, Borglykke A, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kavousi M, Hughes M, Müezzinler A, Holleczek B, Franco OH, Hofman A, Boffetta P, Trichopoulou A, Kee F.

Repeated measures of body mass index and C-reactive protein in relation to all-cause mortality and cardiovascular disease: results from the consortium on health and ageing network of cohorts in Europe and the United States (CHANCES).

Eur J Epidemiol. 2014 Dec;29(12):887-97. doi: 10.1007/s10654-014-9954-8. Epub 2014 Nov 25.


Wild B, Eckl A, Herzog W, Niehoff D, Lechner S, Maatouk I, Schellberg D, Brenner H, Müller H, Löwe B.

Assessing generalized anxiety disorder in elderly people using the GAD-7 and GAD-2 scales: results of a validation study.

Am J Geriatr Psychiatry. 2014 Oct;22(10):1029-38. doi: 10.1016/j.jagp.2013.01.076. Epub 2013 Jun 12.


Saum KU, Dieffenbach AK, Müezzinler A, Müller H, Holleczek B, Stegmaier C, Butterbach K, Schick M, Canzian F, Stammer H, Boukamp P, Hauer K, Brenner H.

Frailty and telomere length: Cross-sectional analysis in 3537 older adults from the ESTHER cohort.

Exp Gerontol. 2014 Aug 21;58C:250-255. doi: 10.1016/j.exger.2014.08.009.


Wild B, Heider D, Maatouk I, Slaets J, König HH, Niehoff D, Saum KU, Brenner H, Söllner W, Herzog W.

Significance and costs of complex biopsychosocial health care needs in elderly people: results of a population-based study.

Psychosom Med. 2014 Sep;76(7):497-502. doi: 10.1097/PSY.0000000000000080.


Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC, Chenevix-Trench G; kConFab Investigators; Australian Ovarian Cancer Study Group, Swerdlow A, Ashworth A, Orr N, Schoemaker M, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Bojesen SE, Nordestgaard BG, Flyger H, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Wang X, Olson JE, Vachon C, Purrington K, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Dunning AM, Shah M, Guénel P, Truong T, Sanchez M, Mulot C, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, Collée JM, Jager A, Cox A, Brock IW, Reed MW, Devilee P, Tollenaar RA, Seynaeve C, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Dumont M, Soucy P, Dörk T, Bogdanova NV, Hamann U, Försti A, Rüdiger T, Ulmer HU, Fasching PA, Häberle L, Ekici AB, Beckmann MW, Fletcher O, Johnson N, Dos Santos Silva I, Peto J, Radice P, Peterlongo P, Peissel B, Mariani P, Giles GG, Severi G, Baglietto L, Sawyer E, Tomlinson I, Kerin M, Miller N, Marme F, Burwinkel B, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Alnæs GG, Kristensen V, Børresen-Dale AL, García-Closas M, Chanock SJ, Lissowska J, Figueroa JD, Schmidt MK, Broeks A, Verhoef S, Rutgers EJ, Brauch H, Brüning T, Ko YD; The GENICA Network, Couch FJ, Toland AE; The TNBCC, Yannoukakos D, Pharoah PD, Hall P, Benítez J, Malats N, Easton DF.

A large-scale assessment of two-way SNP interactions in breast cancer suceptibility using 46.450 cases and 42.461 controls from the Breast Cancer Association Consortium.

Hum Mol Genet. 2014 Apr 1;23(7):1934-46. doi: 10.1093/hmg/ddt581.


The Emerging Risk Factors Collaboration*.

Glycated hemoglobin measurement and prediction of cardiovascular disease.

JAMA. 2014 Mar 26;311(12):1225-33. doi: 10.1001/jama.2014.1873.

* Authors on behalf of the ESTHER study: Brenner H.


Pennells L, Kaptoge S, White IR, Thompson SG, Wood AM; Emerging Risk Factors Collaboration*.

Assessing risk prediction models using individual participant data from multiple studies.

Am J Epidemiol. 2014 Mar 1;179(5):621-32. doi: 10.1093/aje/kwt298.

* Authors on behalf of the ESTHER study: Brenner H, Schöttker B, Müller H,

Rothenbacher D.


Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H.

Cross-sectional and longitudinal changes in DNA methylation with age: An epigenome-wide analysis revealing over 60 novel age-associated CpG sites.

Hum Mol Genet. 2014 Mar 1;23(5):1186-201. doi: 10.1093/hmg/ddt531.


Schöttker B, Saum KU, Perna L, Ordóñez-Mena JM, Holleczek B, Brenner H.

Is vitamin D deficiency a cause of increased morbidity and mortality at older age or simply an indicator of poor health?

Eur J Epidemiol. 2014 Mar;29(3):199-210. doi: 10.1007/s10654-014-9894-3.


Saum KU, Dieffenbach AK, Müller H, Holleczek B, Hauer K, Brenner H.

Frailty prevalence and 10-year survival in community-dwelling older adults: results from the ESTHER cohort study.

Eur J Epidemiol. 2014 Mar;29(3):171-9. doi: 10.1007/s10654-014-9891-6.


Agarwal D, Pineda S, Michailidou K, Herranz J, Pita G, Moreno LT, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Zamora P, Benítz J, Milne RL.

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium.

Br J Cancer. 2014 Feb 18; 110(4): 1088–1100. Published online 2014 Feb 18. doi: 10.1038/bjc.2013.769


Heider D, Matschinger H, Müller H, Saum KU, Quinzler R, Haefeli WE, Wild B, Lehnert T, Brenner H, König HH.

Health care costs in the elderly in Germany: an analysis applying Andersen's behavioral model of health care utilization.

BMC Health Serv Res. 2014 Feb 14;14:71. doi: 10.1186/1472-6963-14-71.


Wen CP, Matsushita K, Coresh J, Iseki K, Islam M, Katz R, McClellan W, Peralta CA, Wang H, de Zeeuw D, Astor BC, Gansevoort RT, Levey AS, Levin A, and the Chronic Kidney Disease Prognosis Consortium*.

Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar.

Kidney Int. 2014 Feb 12. doi: 10.1038/ki.2013.553.

* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller H,

Schöttker B.


Bock JO, Matschinger H, Brenner H, Wild B, Haefeli WE, Quinzler R, Saum KU, Heider D, König HH.

Inequalities in out-of-pocket payments for health care services among elderly Germans--results of a population-based cross-sectional study.

Int J Equity Health. 2014 Jan 8;13(1):3. doi: 10.1186/1475-9276-13-3.


Zhang Y, Yang R, Burwinkel B, Breitling LP, Brenner H.

F2RL3 methylation as a biomarker of current and lifetime smoking exposures.

Environmental Health Perspectives 2014; 122: 131-137.


Schoeps A, Rudolph A, Seibold P, Dunning AM, Milne RL, Bojesen SE, Swerdlow A, Andrulis I, Brenner H, Behrens S, Orr N, Jones M, Ashworth A, Li J, Cramp H, Connley D, Czene K, Darabi H, Chanock SJ, Lissowska J, Figueroa JD, Knight J, Glendon G, Mulligan AM, Dumont M, Severi G, Baglietto L, Olson J, Vachon C, Purrington K, Moisse M, Neven P, Wildiers H, Spurdle A, Kosma VM, Kataja V, Hartikainen JM, Hamann U, Ko YD, Dieffenbach AK, Arndt V, Stegmaier C, Malats N, Arias Perez JI, Benítez J, Flyger H, Nordestgaard BG, Truong T, Cordina-Duverger E, Menegaux F, dos Santos Silva I, Fletcher O, Johnson N, Häberle L, Beckmann MW, Ekici AB, Braaf L, Atsma F, van den Broek AJ, Makalic E, Schmidt DF, Southey MC, Cox A, Simard J, Giles GG, Lambrechts D, Mannermaa A, Brauch H, Guénel P, Peto J, Fasching PA, Hopper J, Flesch-Janys D, Couch F, Chenevix-Trench G, Pharoah PD, Garcia-Closas M, Schmidt MK, Hall P, Easton DF, Chang-Claude J.

Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions.

Genetic Epidemiology 2014; 38: 84-93.


Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, Brennan P, Luce D, Stucker I, Matsuo K, Talamini R, La Vecchia C, Olshan AF, Winn DM, Herreror R, Franceschi S, Castellsague X, Muscat J, Morgenstern H, Zhang ZF, Levi F, Dal Maso L, Kelsey K, McClean M, Vaughan TL, Lazarus P, Purdue MP, Hayes RB, Chen C, Schwartz SM, Shangina O, Koifman S, Ahrens W, Matos E, Lagiou P, Lissowska J, Szeszenia-Dabrowska N, Fernandez L, Menezes A, Agudo A, Daudt AW, Richiardi L, Kjaerheim K, Mates D, Betka J, Yu GP, Schantz S, Simonato L, Brenner H, Conway DI, Macfarlane TV, Thomson P, Fabianova E, Znaor A, rudnai P, Healy C, Boffetta P, Chuang SC, Lee YC, Hashibe M, Boccia S.

Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium.

Eur J Epidemiol. 2014 Jan;29(1):35-48. doi: 10.1007/s10654-013-9863-2.


Perna L, Mons U, Kliegel M, Brenner H.

Serum 25-hydroxyvitamin D and cognitive decline: a longitudinal study among non-demented older adults.

Dement Geriatr Cogn Disord. 2014;38(3-4):254-63. doi: 10.1159/000362870.

 


2013


Perna L, Schöttker B, Holleczek B, Brenner H.
Serum 25-hydroxyvitamin D and incidence of fatal and non-fatal cardiovascular events: a prospective study with repeated measurements.
Journal of Clinical Endocrinology & Metabolism 2013; 98: 4908-4915.

Perna L, Hoffmeister M, Schöttker B, Arndt V, Haug U, Holleczek B, Burwinkel B, Ordonez-Mena JM, Brenner H.
Vitamin D receptor polymorphism and colorectal cancer-specific and all-cause mortality.
Cancer Epidemiology 2013; 37: 905-907.

Silbernagel G, Schöttker B, Appelbaum S, Scharnagl H, Kleber ME, Grammer TB, Ritsch A, Mons U, Holleczek B, Goliasch G, Niessner A, Boehm BO, Schnabel RB, Brenner H, Blankenberg S, Landmesser U, März W.
High-density lipoprotein cholesterol, coronary artery disease and cardiovascular mortality.
European Heart Journal 2013; 34: 3563-71.

Breitling LP, Olsen H, Müller H, Schöttker B, Kliegel M, Brenner H.
Self- or physician-reported diabetes, glycemia markers, and cognitive functioning in older adults in Germany.
American Journal of Geriatric Psychiatry 2013; S1064-7481(13)00282-0.

Wild B, Eckl A, Herzog W, Niehoff D, Lechner S, Maatouk I, Schellberg D, Brenner H, Müller H, Löwe B.
Assessing generalized anxiety disorder in elderly people by use of the GAD-7 and GAD-2 scales - results of a validation study.
American Journal of Geriatric Psychiatry 2013; S1064-7481(13)00116-4.

Matsushita K, Ballew SH, Astor BC, de Jong PE, Gansevoort RT, Hemmelgarn BR, Levey AS, Levin A, Wen C-P, Woodward M, Coresh J, and for the CKD Prognosis Consortium*.
Cohort profile: the chronic kidney disease prognosis consortium.
International Journal of Epidemiology 2013; 42: 1660-1668.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller H,

Schöttker B.

Yin L, Ordonez-Mena JM, Chen T, Schöttker B, Arndt V, Brenner H.
Circulating 25-hydroxyvitamin D serum concentration and total cancer incidence and mortality: a systematic review and meta-analysis.
Preventive Medicine 2013; 57: 753-764.

Schöttker B, Brenner H, Koenig W, Müller H, Rothenbacher D.
Prognostic association of HbA1c and fasting plasma glucose with reduced kidney function in subjects with and without diabetes mellitus. Results from a population-based cohort study from Germany.
Preventive Medicine 2013; 57: 596-600.

Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, Kaptoge S, Whitlock g, Qiao Q, Lewington s, Di Angelantonio E, van der Hoorn S, Lawes CMM, Ali MK, Mozaffarian D, Ezzati M, Global Burdon of Metabolic Risk Factors of Chronic Diseases Collaborating Group, Asia-Pacific Cohort Studies Collaboration (APCSC), Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in Europe (DECODE), Emerging risk Factor Collaboration (ERFC)*, Prospective Studies Collaboration (PSC).
The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: A pooled analysis.
PloS One 2013; 8:e65174.
*Authors on behalf of the ESTHER study: Brenner H, Schöttker B, Müller H,

Rothenbacher D.

Mons U, Schöttker B, Müller H, Kliegel M, Brenner H.
History of lifetime smoking, smoking cessation and cognitive function in the elderly population.
European Journal of Epidemiology 2013; 28:823-831.

Pesatori AC, Carugno M, Consonni D, Hung RJ, Papadoupolos A, Landi M, Brenner H, Müller H, Harris C, Duell E, Andrew A, McLaughlin J, Schwartz AG, Wenzlaff A, Stucker I.
Hormone use and risk for lung cancer: a pooled analysis from the International Lung Cancer Consortium (ILCCO).
British Journal of Cancer 2013; 109:1954-1964.

Yu OH, Foulkes WD, Dastani Z, Martin RM, Eeles R, PRACTICAL Consortium*, CRUK GWAS Investigators, Richards JB.
An assessment of the shared allelic architecture between type II diabetes and prostate cancer.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22:1473-1475.
*Author on behalf of the ESTHER study: Brenner H.

Gellert C, Schöttker B, Müller H, Holleczek B, Brenner H.
Impact of smoking and quitting on cardiovascular outcomes and risk advancement periods among older adults.
European Journal of Epidemiology 2013; 28:648-658.

Shlipak MG, Matsushita K, Ärnlöv J, Inker LA, Katz R, Polkinghorne K, Rothenbacher D, Sarnak MJ, Astor BC, Coresh J, Levey AS, Gansevoort RT, for the CKD Prognosis Consortium.*

Cystatin C versus creatinine for determining risk based on kidney function.
New England Journal of Medicine 2013; 369:932-943.
*Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Schöttker B,

Koenig W.

Kote-Jarai Z, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Dadaev T, Jugurnauth-Little S, Ross-Adams H, Al Olama AA, Benlloch S, Halim S, Russell R, Dunning AM, Luccarini C, Dennis J, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock S, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah P, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle A, Clements JA, Teixeira MR, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dicks E, Baynes C, Conroy D, Bojesen SE, Kaaks R, Vincent D, Bacot F, Tessier DC; COGS-CRUK GWAS-ELLIPSE (Part of GAME-ON) Initiative; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium, Easton DF, Eeles RA.
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.
Human Molecular Genetics 2013; 22: 2520-2528.

Ordóñez-Mena JM, Schöttker B, Haug U, Müller H, Köhrle J, Schomburg L, Holleczek B, Brenner H.
Serum 25-hydroxyvitamin D and cancer risk in older adults. Results from a large German prospective cohort study.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 905-916.

Zhang Y, Weck MN, Schöttker B, Rothenbacher D, Brenner H.
Gastric parietal cell antibodies, Helicobacter pylori infection, and chronic atrophic gastritis: Evidence from a large population-based study in Germany.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 821-826.

Shen H, Fridley BL, Song H, Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS, Tyrer J, Stram D, Larson MC, Köbel M; PRACTICAL Consortium, Ziogas A, Zheng W, Yang HP, Wu AH, Wozniak EL, Woo YL, Winterhoff B, Wik E, Whittemore AS, Wentzensen N, Weber RP, Vitonis AF, Vincent D, Vierkant RA, Vergote I, Van Den Berg D, Van Altena AM, Tworoger SS, Thompson PJ, Tessier DC, Terry KL, Teo SH, Templeman C, Stram DO, Southey MC, Sieh W, Siddiqui N, Shvetsov YB, Shu XO, Shridhar V, Wang-Gohrke S, Severi G, Schwaab I, Salvesen HB, Rzepecka IK, Runnebaum IB, Rossing MA, Rodriguez-Rodriguez L, Risch HA, Renner SP, Poole EM, Pike MC, Phelan CM, Pelttari LM, Pejovic T, Paul J, Orlow I, Omar SZ, Olson SH, Odunsi K, Nickels S, Nevanlinna H, Ness RB, Narod SA, Nakanishi T, Moysich KB, Monteiro AN, Moes-Sosnowska J, Modugno F, Menon U, McLaughlin JR, McGuire V, Matsuo K, Adenan NA, Massuger LF, Lurie G, Lundvall L, Lubiński J, Lissowska J, Levine DA, Leminen A, Lee AW, Le ND, Lambrechts S, Lambrechts D, Kupryjanczyk J, Krakstad C, Konecny GE, Kjaer SK, Kiemeney LA, Kelemen LE, Keeney GL, Karlan BY, Karevan R, Kalli KR, Kajiyama H, Ji BT, Jensen A, Jakubowska A, Iversen E, Hosono S, Høgdall CK, Høgdall E, Hoatlin M, Hillemanns P, Heitz F, Hein R, Harter P, Halle MK, Hall P, Gronwald J, Gore M, Goodman MT, Giles GG, Gentry-Maharaj A, Garcia-Closas M, Flanagan JM, Fasching PA, Ekici AB, Edwards R, Eccles D, Easton DF, Dürst M, du Bois A, Dörk T, Doherty JA, Despierre E, Dansonka-Mieszkowska A, Cybulski C, Cramer DW, Cook LS, Chen X, Charbonneau B, Chang-Claude J, Campbell I, Butzow R, Bunker CH, Brueggmann D, Brown R, Brooks-Wilson A, Brinton LA, Bogdanova N, Block MS, Benjamin E, Beesley J, Beckmann MW, Bandera EV, Baglietto L, Bacot F, Armasu SM, Antonenkova N, Anton-Culver H, Aben KK, Liang D, Wu X, Lu K, Hildebrandt MA; Australian Ovarian Cancer Study Group; Australian Cancer Study, Schildkraut JM, Sellers TA, Huntsman D, Berchuck A, Chenevix-Trench G, Gayther SA, Pharoah PD, Laird PW, Goode EL, Pearce CL.
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
Nature Communications 2013; 4:1628. Doi: 10.1038/ncomms2629.
* Author on behalf of the ESTHER study: Brenner H.

Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC; COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative; Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators; PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, Kote-Jarai Z, Easton DF.
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Nature Genetics 2013; 45: 385-391.

Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S, Baynes C, Bolla MK, Wang Q, Dennis J, McGuffog L, Barrowdale D, Lee A, Healey S, Lush M, Tessier DC, Vincent D, Bacot F; Australian Cancer Study; Australian Ovarian Cancer Study; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab); Gene Environment Interaction and Breast Cancer (GENICA); Swedish Breast Cancer Study (SWE-BRCA); Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE); Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO), Vergote I, Lambrechts S, Despierre E, Risch HA, González-Neira A, Rossing MA, Pita G, Doherty JA, Alvarez N, Larson MC, Fridley BL, Schoof N, Chang-Claude J, Cicek MS, Peto J, Kalli KR, Broeks A, Armasu SM, Schmidt MK, Braaf LM, Winterhoff B, Nevanlinna H, Konecny GE, Lambrechts D, Rogmann L, Guénel P, Teoman A, Milne RL, Garcia JJ, Cox A, Shridhar V, Burwinkel B, Marme F, Hein R, Sawyer EJ, Haiman CA, Wang-Gohrke S, Andrulis IL, Moysich KB, Hopper JL, Odunsi K, Lindblom A, Giles GG, Brenner H, Simard J, Lurie G, Fasching PA, Carney ME, Radice P, Wilkens LR, Swerdlow A, Goodman MT, Brauch H, Garcia-Closas M, Hillemanns P, Winqvist R, Dürst M, Devilee P, Runnebaum I, Jakubowska A, Lubinski J, Mannermaa A, Butzow R, Bogdanova NV, Dörk T, Pelttari LM, Zheng W, Leminen A, Anton-Culver H, Bunker CH, Kristensen V, Ness RB, Muir K, Edwards R, Meindl A, Heitz F, Matsuo K, du Bois A, Wu AH, Harter P, Teo SH, Schwaab I, Shu XO, Blot W, Hosono S, Kang D, Nakanishi T, Hartman M, Yatabe Y, Hamann U, Karlan BY, Sangrajrang S, Kjaer SK, Gaborieau V, Jensen A, Eccles D, Høgdall E, Shen CY, Brown J, Woo YL, Shah M, Azmi MA, Luben R, Omar SZ, Czene K, Vierkant RA, Nordestgaard BG, Flyger H, Vachon C, Olson JE, Wang X, Levine DA, Rudolph A, Weber RP, Flesch-Janys D, Iversen E, Nickels S, Schildkraut JM, Silva Idos S, Cramer DW, Gibson L, Terry KL, Fletcher O, Vitonis AF, van der Schoot CE, Poole EM, Hogervorst FB, Tworoger SS, Liu J, Bandera EV, Li J, Olson SH, Humphreys K, Orlow I, Blomqvist C, Rodriguez-Rodriguez L, Aittomäki K, Salvesen HB, Muranen TA, Wik E, Brouwers B, Krakstad C, Wauters E, Halle MK, Wildiers H, Kiemeney LA, Mulot C, Aben KK, Laurent-Puig P, Altena AM, Truong T, Massuger LF, Benitez J, Pejovic T, Perez JI, Hoatlin M, Zamora MP, Cook LS, Balasubramanian SP, Kelemen LE, Schneeweiss A, Le ND, Sohn C, Brooks-Wilson A, Tomlinson I, Kerin MJ, Miller N, Cybulski C, Henderson BE, Menkiszak J, Schumacher F, Wentzensen N, Le Marchand L, Yang HP, Mulligan AM, Glendon G, Engelholm SA, Knight JA, Høgdall CK, Apicella C, Gore M, Tsimiklis H, Song H, Southey MC, Jager A, den Ouweland AM, Brown R, Martens JW, Flanagan JM, Kriege M, Paul J, Margolin S, Siddiqui N, Severi G, Whittemore AS, Baglietto L, McGuire V, Stegmaier C, Sieh W, Müller H, Arndt V, Labrèche F, Gao YT, Goldberg MS, Yang G, Dumont M, McLaughlin JR, Hartmann A, Ekici AB, Beckmann MW, Phelan CM, Lux MP, Permuth-Wey J, Peissel B, Sellers TA, Ficarazzi F, Barile M, Ziogas A, Ashworth A, Gentry-Maharaj A, Jones M, Ramus SJ, Orr N, Menon U, Pearce CL, Brüning T, Pike MC, Ko YD, Lissowska J, Figueroa J, Kupryjanczyk J, Chanock SJ, Dansonka-Mieszkowska A, Jukkola-Vuorinen A, Rzepecka IK, Pylkäs K, Bidzinski M, Kauppila S, Hollestelle A, Seynaeve C, Tollenaar RA, Durda K, Jaworska K, Hartikainen JM, Kosma VM, Kataja V, Antonenkova NN, Long J, Shrubsole M, Deming-Halverson S, Lophatananon A, Siriwanarangsan P, Stewart-Brown S, Ditsch N, Lichtner P, Schmutzler RK, Ito H, Iwata H, Tajima K, Tseng CC, Stram DO, van den Berg D, Yip CH, Ikram MK, Teh YC, Cai H, Lu W, Signorello LB, Cai Q, Noh DY, Yoo KY, Miao H, Iau PT, Teo YY, McKay J, Shapiro C, Ademuyiwa F, Fountzilas G, Hsiung CN, Yu JC, Hou MF, Healey CS, Luccarini C, Peock S, Stoppa-Lyonnet D, Peterlongo P, Rebbeck TR, Piedmonte M, Singer CF, Friedman E, Thomassen M, Offit K, Hansen TV, Neuhausen SL, Szabo CI, Blanco I, Garber J, Narod SA, Weitzel JN, Montagna M, Olah E, Godwin AK, Yannoukakos D, Goldgar DE, Caldes T, Imyanitov EN, Tihomirova L, Arun BK, Campbell I, Mensenkamp AR, van Asperen CJ, van Roozendaal KE, Meijers-Heijboer H, Collée JM, Oosterwijk JC, Hooning MJ, Rookus MA, van der Luijt RB, Os TA, Evans DG, Frost D, Fineberg E, Barwell J, Walker L, Kennedy MJ, Platte R, Davidson R, Ellis SD, Cole T, Bressac-de Paillerets B, Buecher B, Damiola F, Faivre L, Frenay M, Sinilnikova OM, Caron O, Giraud S, Mazoyer S, Bonadona V, Caux-Moncoutier V, Toloczko-Grabarek A, Gronwald J, Byrski T, Spurdle AB, Bonanni B, Zaffaroni D, Giannini G, Bernard L, Dolcetti R, Manoukian S, Arnold N, Engel C, Deissler H, Rhiem K, Niederacher D, Plendl H, Sutter C, Wappenschmidt B, Borg A, Melin B, Rantala J, Soller M, Nathanson KL, Domchek SM, Rodriguez GC, Salani R, Kaulich DG, Tea MK, Paluch SS, Laitman Y, Skytte AB, Kruse TA, Jensen UB, Robson M, Gerdes AM, Ejlertsen B, Foretova L, Savage SA, Lester J, Soucy P, Kuchenbaecker KB, Olswold C, Cunningham JM, Slager S, Pankratz VS, Dicks E, Lakhani SR, Couch FJ, Hall P, Monteiro AN, Gayther SA, Pharoah PD, Reddel RR, Goode EL, Greene MH, Easton DF, Berchuck A, Antoniou AC, Chenevix-Trench G, Dunning AM.
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Nature Genetics 2013; 45: 371-384.

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N; Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Henderson BE, Schumacher F, Le Marchand L, Andrulis IL, Knight JA, Glendon G, Mulligan AM; kConFab Investigators; Australian Ovarian Cancer Study Group, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Bui QM, Stone J, Dite GS, Apicella C, Tsimiklis H, Giles GG, Severi G, Baglietto L, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H, Müller H, Arndt V, Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M, Figueroa J, Lissowska J, Brinton L, Goldberg MS, Labrèche F, Dumont M, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U, Brüning T; GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network, Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee P, Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J, Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Bogdanova NV, Antonenkova NN, Dörk T, Kristensen VN, Anton-Culver H, Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo K, Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Shu XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK, Hartman M, Miao H, Lim WY, Sng JH, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Simard J, Garcia-Closas M, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J, Easton DF.
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Nature Genetics 2013; 45: 353-361.

French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D, Tessier DC, Vincent D, Bacot F, Luccarini C, Baynes C, Conroy D, Dennis J, Bolla MK, Wang Q, Hopper JL, Southey MC, Schmidt MK, Broeks A, Verhoef S, Cornelissen S, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Loehberg CR, Ekici AB, Beckmann MW, Peto J, dos Santos Silva I, Johnson N, Aitken Z, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Zamora MP, Arias Perez JI, Benitez J, Anton-Culver H, Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Engel C, Brauch H, Hamann U, Justenhoven C; GENICA Network, Aaltonen K, Heikkilä P, Aittomäki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Sueta A, Bogdanova NV, Antonenkova NN, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab Investigators, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Lambrechts D, Peeters S, Smeets A, Floris G, Chang-Claude J, Rudolph A, Nickels S, Flesch-Janys D, Radice P, Peterlongo P, Bonanni B, Sardella D, Couch FJ, Wang X, Pankratz VS, Lee A, Giles GG, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip CH, Ng CH, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Devilee P, Seynaeve C, García-Closas M, Figueroa J, Chanock SJ, Lissowska J, Czene K, Klevebring D, Schoof N, Hooning MJ, Martens JW, Collée JM, Tilanus-Linthorst M, Hall P, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cox A, Balasubramanian SP, Blot W, Signorello LB, Cai Q, Pharoah PD, Healey CS, Shah M, Pooley KA, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Sng JH, Sim X, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, McKay J, Toland AE, Ambrosone CB, Yannoukakos D, Godwin AK, Shen CY, Hsiung CN, Wu PE, Chen ST, Swerdlow A, Ashworth A, Orr N, Schoemaker MJ, Ponder BA, Nevanlinna H, Brown MA, Chenevix-Trench G, Easton DF, Dunning AM.
Functional variants at the 11q13 risk locus for breast cancer regulate Cyclin D1 expression through long-range enhancers.
American Journal of Human Genetics 2013; 92: 489-503.

Nickels S, Truong T, Hein R, Stevens K, Buck K, Behrens S, Eilber U, Schmidt M, Häberle L, Vrieling A, Gaudet M, Figueroa J, Schoof N, Spurdle AB, Rudolph A, Fasching PA, Hopper JL, Makalic E, Schmidt DF, Southey MC, Beckmann MW, Ekici AB, Fletcher O, Gibson L, Silva Idos S, Peto J, Humphreys MK, Wang J, Cordina-Duverger E, Menegaux F, Nordestgaard BG, Bojesen SE, Lanng C, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Müller H, Arndt V, Stegmaier C, Brauch H, Brüning T, Harth V; Genica Network, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab; AOCS Management Group, Lambrechts D, Smeets D, Neven P, Paridaens R, Flesch-Janys D, Obi N, Wang-Gohrke S, Couch FJ, Olson JE, Vachon CM, Giles GG, Severi G, Baglietto L, Offit K, John EM, Miron A, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Chanock SJ, Lissowska J, Liu J, Cox A, Cramp H, Connley D, Balasubramanian S, Dunning AM, Shah M, Trentham-Dietz A, Newcomb P, Titus L, Egan K, Cahoon EK, Rajaraman P, Sigurdson AJ, Doody MM, Guénel P, Pharoah PD, Schmidt MK, Hall P, Easton DF, Garcia-Closas M, Milne RL, Chang-Claude J.
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.
PLoS Genetics 2013; 9: e1003284.

Schöttker B, Herder C, Rothenbacher D, Perna L, Müller H, Brenner H.
Serum 25-hydroxyvitamin D levels and incident diabetes mellitus type 2. A competing risk analysis in a large population-based cohort of older adults.
European Journal of Epidemiology 2013; 28: 267-275.

Schöttker B, Haug U, Schomburg L, Köhrle J, Perna L, Müller H, Holleczek B, Brenner H.
Strong associations of 25-hydroxyvitamin D levels with all-cause, cardiovascular, cancer and respiratory disease mortality in a large cohort study.
The American Journal of Clinical Nutrition 2013; 97: 782-793.

Perna L, Butterbach K, Haug U, Schöttker B, Müller H, Arndt V, Holleczek B, Burwinkel B, Brenner H.
Vitamin D receptor genotype rs731236 (Taq1) and breast cancer prognosis.
Cancer Epidemiology, Biomarkers & Prevention 2013; 22: 437-442.

Nitsch D, Grams M, Sang Y, Black C, Cirillo M, Djurdjev O, Iseki K, Jassal SK, Kimm H, Kronenberg F, Øien CM, Levey AS, Levin A, Woodward M, Hemmelgarn BR, for the CKD Prognosis Consortium.*

Do the associations of eGFR and albuminuria with mortality and renal failure differ by gender? A meta-analysis from a global consortium.
British Medical Journal 2013; 346:f324.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Müller H,

Schöttker B.

Amin Al Olama A, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Hunter DJ, Henderson BE, Thun MJ, Gaziano M, Giovannucci EL, Siddiq A, Travis RC, Cox DG, Canzian F, Riboli E, Key TJ, Andriole G, Albanes D, Hayes RB, Schleutker J, Auvinen A, Tammela TL, Weischer M, Stanford JL, Ostrander EA, Cybulski C, Lubinski J, Thibodeau SN, Schaid DJ, Sorensen KD, Batra J, Clements JA, Chambers S, Aitken J, Gardiner RA, Maier C, Vogel W, Dörk T, Brenner H, Habuchi T, Ingles S, John EM, Dickinson JL, Cannon-Albright L, Teixeira MR, Kaneva R, Zhang HW, Lu YJ, Park JY, Cooney KA, Muir KR, Leongamornlert DA, Saunders E, Tymrakiewicz M, Mahmud N, Guy M, Govindasami K, O'Brien LT, Wilkinson RA, Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL, English D, Virtamo J, Le Marchand L, Campa D, Kaaks R, Lindstrom S, Diver WR, Gapstur S, Yeager M, Cox A, Stern MC, Corral R, Aly M, Isaacs W, Adolfsson J, Xu J, Zheng SL, Wahlfors T, Taari K, Kujala P, Klarskov P, Nordestgaard BG, Røder MA, Frikke-Schmidt R, Bojesen SE, FitzGerald LM, Kolb S, Kwon EM, Karyadi DM, Orntoft TF, Borre M, Rinckleb A, Luedeke M, Herkommer K, Meyer A, Serth J, Marthick JR, Patterson B, Wokolorczyk D, Spurdle A, Lose F, McDonnell SK, Joshi AD, Shahabi A, Pinto P, Santos J, Ray A, Sellers TA, Lin HY, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Tsuchiya N, Narita S, Cao GW, Slavov C, Mitev V; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; Australian Prostate Cancer Bioresource; PRACTICAL Consortium, Chanock S, Gronberg H, Haiman CA, Kraft P, Easton DF, Eeles RA.
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.
Human Molecular Genetics 2013; 22: 408-415.

Schöttker B, Herder C, Rothenbacher D, Roden M, Kolb H, Müller H, Brenner H.
Proinflammatory cytokines, adiponectin and increased risk of primary cardiovascular events in patients with diabetes and renal dysfunction: results from the ESTHER study.
Diabetes Care 2013; 36: 1703-1711.

Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q, Dennis J, Dicks E, Howat WJ, Schoof N, Bojesen SE, Lambrechts D, Broeks A, Andrulis IL, Guénel P, Burwinkel B, Sawyer EJ, Hollestelle A, Fletcher O, Winqvist R, Brenner H, Mannermaa A, Hamann U, Meindl A, Lindblom A, Zheng W, Devillee P, Goldberg MS, Lubinski J, Kristensen V, Swerdlow A, Anton-Culver H, Dörk T, Muir K, Matsuo K, Wu AH, Radice P, Teo SH, Shu XO, Blot W, Kang D, Hartman M, Sangrajrang S, Shen CY, Southey MC, Park DJ, Hammet F, Stone J, Veer LJ, Rutgers EJ, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Peto J, Schrauder MG, Ekici AB, Beckmann MW, Dos Santos Silva I, Johnson N, Warren H, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Truong T, Laurent-Puig P, Kerbrat P, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Perez JI, Menéndez P, Müller H, Arndt V, Stegmaier C, Lichtner P, Lochmann M, Justenhoven C, Ko YD; Gene ENvironmental Interaction and breast CAncer (GENICA) Network, Muranen TA, Aittomäki K, Blomqvist C, Greco D, Heikkinen T, Ito H, Iwata H, Yatabe Y, Antonenkova NN, Margolin S, Kataja V, Kosma VM, Hartikainen JM, Balleine R; kConFab Investigators, Tseng CC, Berg DV, Stram DO, Neven P, Dieudonné AS, Leunen K, Rudolph A, Nickels S, Flesch-Janys D, Peterlongo P, Peissel B, Bernard L, Olson JE, Wang X, Stevens K, Severi G, Baglietto L, McLean C, Coetzee GA, Feng Y, Henderson BE, Schumacher F, Bogdanova NV, Labrèche F, Dumont M, Yip CH, Taib NA, Cheng CY, Shrubsole M, Long J, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Knight JA, Glendon G, Mulligan AM, Tollenaar RA, Seynaeve CM, Kriege M, Hooning MJ, van den Ouweland AM, van Deurzen CH, Lu W, Gao YT, Cai H, Balasubramanian SP, Cross SS, Reed MW, Signorello L, Cai Q, Shah M, Miao H, Chan CW, Chia KS, Jakubowska A, Jaworska K, Durda K, Hsiung CN, Wu PE, Yu JC, Ashworth A, Jones M, Tessier DC, González-Neira A, Pita G, Alonso MR, Vincent D, Bacot F, Ambrosone CB, Bandera EV, John EM, Chen GK, Hu JJ, Rodriguez-Gil JL, Bernstein L, Press MF, Ziegler RG, Millikan RM, Deming-Halverson SL, Nyante S, Ingles SA, Waisfisz Q, Tsimiklis H, Makalic E, Schmidt D, Bui M, Gibson L, Müller-Myhsok B, Schmutzler RK, Hein R, Dahmen N, Beckmann L, Aaltonen K, Czene K, Irwanto A, Liu J, Turnbull C; Familial Breast Cancer Study (FBCS), Rahman N, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F; Australian Breast Cancer Tissue Bank (ABCTB) Investigators, Olswold C, Slager S, Pilarski R, Ademuyiwa F, Konstantopoulou I, Martin NG, Montgomery GW, Slamon DJ, Rauh C, Lux MP, Jud SM, Bruning T, Weaver J, Sharma P, Pathak H, Tapper W, Gerty S, Durcan L, Trichopoulos D, Tumino R, Peeters PH, Kaaks R, Campa D, Canzian F, Weiderpass E, Johansson M, Khaw KT, Travis R, Clavel-Chapelon F, Kolonel LN, Chen C, Beck A, Hankinson SE, Berg CD, Hoover RN, Lissowska J, Figueroa JD, Chasman DI, Gaudet MM, Diver WR, Willett WC, Hunter DJ, Simard J, Benitez J, Dunning AM, Sherman ME, Chenevix-Trench G, Chanock SJ, Hall P, Pharoah PD, Vachon C, Easton DF, Haiman CA, Kraft P.
Genome-wide association studies identify four ER-negative specific breast cancer risk loci.
Nature Genetics 2013; 45: 392-398.

Schöttker B, Müller H, Rothenbacher D, Brenner H.
Fasting plasma glucose and HbA1c in cardiovascular risk prediction: a sex-specific comparison in individuals without diabetes mellitus.
Diabetologia 2013; 56: 92-100.

Gellert C, Schöttker B, Holleczek B, Stegmaier C, Müller H, Brenner H.
Using rate advancement periods for communicating the benefits of quitting to older smokers.
Tobacco Control 2013; 22: 227-230.

Perna L, Felix J, Breitling LP, Haug U, Raum E, Burwinkel B, Schöttker B, Brenner H.
Genetic variations in the vitamin D binding protein and season specific serum levels of 25-hydroxyvitamin D among older adults.
Epidemiology 2013; 24: 104-109.

 


2012


Breitling LP, Perna L, Müller H, Raum E, Kliegel M, Brenner H.
Vitamin D and cognitive functioning in the elderly population in Germany.
Experimental Gerontology 2012; 47: 122-127.

Chuang SC, Jenab M, Heck JE, Bosetti C, Talamini R, Matsuo K, Castellsague X, Franceschi S, Herrero R, Winn DM, Vecchia CL, Morgenstern H, Zhang ZF, Levi F, Maso LD, Kelsey K, McClean MD, Vaughan T, Lazarus P, Muscat J, Ramroth H, Chen C, Schwartz SM, Eluf-Neto J, Hayes RB, Purdue M, Boccia S, Cadoni G, Zaridze D, Koifman S, Curado MP, Ahrens W, Benhamou S, Matos E, Lagiou P, Szeszenia-Dabrowska N, Olshan AF, Fernandez L, Menezes A, Agudo A, Daudt AW, Merletti F, Macfarlane GJ, Kjaerheim K, Mates D, Holcatova I, Schantz S, Yu GP, Simonato L, Brenner H, Mueller H, Conway DI, Thomson P, Fabianova E, Znaor A, Rudnai P, Healy CM, Ferro G, Brennan P, Boffetta P, Hashibe M.
Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium.
Cancer Causes and Control 2012; 23: 69-88.

Schöttker B, Adamu MA, Weck MN, Müller H, Brenner H.
Helicobacter pylori infection, chronic atrophic gastritis and major cardiovascular events: a population-based cohort study.
Atherosclerosis 2012; 220: 569-574.

Maatouk I, Wild B, Wesche D, Herzog W, Raum E, Müller H, Rothenbacher D, Stegmaier C, Schellberg D, Brenner H.
Temporal predictors of health-related quality of life in elderly people with diabetes: results of a German cohort study.
PLoS One 2012; 7: e31088.

Stott-Miller M, Chen C, Chuang S-C, Lee YC, Boccia S, Brenner H, Cadoni G, Dal Maso L, La Vecchia C, Lazarus P, Levi F, Matsuo K, Morgenstern H, Muller H, Muscat J, Olshan AF, Purdue MP, Serraino D, Vaughan TL, Zhang Z-F, Boffetta P, Hashibe M, Schwartz SM.
History of diabetes and risk of head and neck cancer:a pooled analysis from the International Head and Neck Cancer Epidemiology (INHANCE) Consortium.
Cancer Epidemiology Biomarkers & Prevention 2012; 21: 294-304.

Frank B, Weck MN, Müller H, Klopp N, Illig T, Raum E, Brenner H.
Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.
European Journal of Cancer 2012; 48: 114-120.

Ghoussaini M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang J, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K, Johnson N, Orr N, dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H, Uitterlinden AG, HEBON, Hall P, Czene K, Irwanto A, Liu J,Nevanlinna H, Aittomäki K, Blomqvist C, Meindl A, Schmutzler RK, Müller-Myhsok B, Chang-Claude J, Hein R, Nickels S, Flesch-Janys D, Tsimiklis H, Makalic E, Schmidt D, Bui M, Hopper JJ, Apicella C, Park DJ, Southey M, Broeks A, Verhoef S, Hogervorst FBL, Fasching PA, Sawyer E, Tomlinson I, Kerin M, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T, Cordina-Duverger E, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Alonso R, González-Neira A, Benítez J, Anton-Culver H, Ziogas A, Bernstein L, Clarke Dur C, Brenner H, Müller H, Arndt V, Stegmaier C, FBCS, Justenhoven C, Brauch H, Pesch B, The GENICA Network, Wang-Gohrke S, Eilber U, Dörk T, Schürmann P, Bremer M, Hillemanns P, Bogdanova NV, Antonenkova NN, Rogov YI, Karstens JH, Bermisheva M, Prokofieva D, Khusnutdinova E, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma V-M, Hartikainen J, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Manoukian S, Bonanni B, Fortuzzi S, Peterlongo P, Radice P, Peterlongo P, Manoukian S, Barile M, Couch FJ, Wang X, Stevens K, Lee A, Giles GG, Baglietto L, Severi G, McLean C, Grenaker Alnæs G, Kristensen V, Børrensen-Dale A-L, John EM, Miron A, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Glendon G, Mulligan AM, Devilee P, van Asperen CJ, Tollenaar RAEM, Seynaeve C, Figueroa JD, Garcia-Closas M, Brinton L, Lissowska J, Hooning MJ, Hollestelle A, Oldenburg RA, van den Ouweland AMW, Cox A, Reed MWR, Shah M, Jakubowska A, Lubinski J, Jaworska K, Durda K, Jones M, Schoemaker M, Ashworth A, Swerdlow A, Beesley J, Chen X, kConFab Investigators, Australian Ovarian Cancer Study Group, Muir KR, Lophatananon A, Rattanamongkongul S, Chaiwerawattana A, Kang D, Yoo K-Y, Noh D-Y, Shen C-Y, Yu J-C, Wu P-E, Hsiung C-N, Perkins A, Swann R, Velentzis L, Eccles DM, Tapper WJ, Gerty SM, Graham NJ, Ponder BA, Chenevix-Trench G, Pharoah PDP, Lathrop M, Dunning AM, Rahman N, Peto J, Easton DF.
Genome-wide association analysis identifies three new breast cancer susceptibility loci.
Nature Genetics 2012; 44: 312-318.

Schöttker B, Herder C, Müller H, Brenner H, Rothenbacher D.
RE: Original Article - Clinical utility of creatinine and cystatin C based definition of renal function for risk prediction of primary cardiovascular events in patients with diabetes.
Diabetes Care 2012; 35: 879-886.

Wild B, Herzog W, Schellberg D, Lechner S, Niehoff D, Brenner H, Rothenbacher D, Stegmaier C, Raum E.
Association between the prevalence of depression and age in a large representative German sample of people aged 53 to 80.
International Journal of Geriatric Psychiatry 2012; 27: 375-381.

Wild B, Herzog W, Lechner S, Niehoff D, Brenner H, Müller H, Rothenbacher D, Stegmaier C, Raum E.
Gender Specific Temporal and Cross-Sectional Associations between BMI-class and Symptoms of Depression in the Elderly.
Journal of Psychosomatic Research 2012; 72: 376-382.

Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, Nickels S, Brauch H, Ko YD, Fischer HP, Network TG, Schmutzler RK, Meindl A, Bartram CR, Schott S, Engel C, Godwin AK, Weaver J, Pathak HB, Sharma P, Brenner H, Müller H, Arndt V, Stegmaier C, Miron P, Yannoukakos D, Stavropoulou A, Fountzilas G, Gogas HJ, Swann R, Dwek M, Perkins KA, Milne RL, Benítez J, Zamora MP, Ignacio Arias Pérez J, Bojesen SE, Nielsen SF, Nordestgaard BG, Flyger H, Guénel P, Truong T, Menegaux F, Cordina-Duverger E, Burwinkel B, Marmé F, Schneeweiss A, Sohn C, Sawyer E, Tomlinson I, Kerin MJ, Peto J, Johnson N, Fletcher O, Dos Santos Silva I, Fasching PA, Beckmann MW, Hartmann A, Ekici AB, Lophatananon A, Muir K, Puttawibul P, Wiangnon S, Schmidt MK, Broeks A, Braaf LM, Rosenberg EH, Hopper JL, Apicella C, Park DJ, Southey MC, Swerdlow AJ, Ashworth A, Orr N, Schoemaker MJ, Anton-Culver H, Ziogas A, Bernstein L, Clarke Dur C, Shen CY, Yu JC, Hsu HM, Hsiung CN, Hamann U, Dünnebier T, Rüdiger T, Ulrich Ulmer H, Pharoah PD, Dunning AM, Humphreys MK, Wang Q, Cox A, Cross SS, Reed MW, Hall P, Czene K, Ambrosone CB, Ademuyiwa F, Hwang H, Eccles DM, Garcia-Closas M, Figueroa JD, Sherman ME, Lissowska J, Devilee P, Seynaeve C, Tollenaar RA, Hooning MJ, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, John EM, Miron A, Grenaker Alnaes G, Kristensen V, Borresen-Dale AL, Giles GG, Baglietto L, McLean CA, Severi G, Kosel ML, Pankratz VS, Slager S, Olson JE, Radice P, Peterlongo P, Manoukian S, Barile M, Lambrechts D, Hatse S, Dieudonne AS, Christiaens MR, Chenevix-Trench G, Investigators K, Group A, Beesley J, Chen X, Mannermaa A, Kosma VM, Hartikainen JM, Soini Y, Easton DF, Couch FJ.
19p13.1 is a triple negative-specific breast cancer susceptibility locus.
Cancer Research 2012; 72: 1795-1803.

Schöttker B, Adamu M, Weck MN, Brenner H.
Helicobacter pylori infection is strongly associated with gastric and duodenal ulcers in a large prospective study.
Clinical Gastroenterology and Hepatology 2012; 10: 487-493.

Matsushita K, Mahmoodi BK, Woodward M, Emberson JR, Jafar TH, Jee SH, Polkinghorne KR, Shankar A, Smith DH, Tonelli M, Warnock DG, Wen C-P, Coresh J, Gansevoort RT, Hemmelgarn BR, Levey AS, for the Chronic Kidney Disease Prognosis Consortium. (Investigators/ Collaborators for the ESTHER study in the Chronic Kidney Disease Prognosis Consortium: Rothenbacher D, Brenner H, Müller H, Schöttker B).
Comparison of risk prediction using the CKD-EPI equation and the MDRD Study equation for estimated glomerular filtration rate.
JAMA 2012; 307: 1941-1951.

Lambrechts D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, Apicella C , Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien R, Sawyer E, Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez JIA, Benítez J, Hamann U, Ko YD, Brüning T, The GENICA Network, Chang-Claude J, Eilber U, Hein R, Nickels S, Flesch-Janys D, Wang-Gohrke S, John EM, Miron A, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Chenevix-Trench G, Beesley J, Chen X, kConFab Investigators, Australian Ovarian Cancer Study Group, Menegaux F, Cordina-Duverger E, Shen C-Y, Yu J-C, Wu P-E, Hou M-F, Andrulis IL, Selander T, Glendon G, Mulligan AM, Anton-Culver H, Ziogas A, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Jones M, Orr N, Ashworth A, Swerdlow A, Severi G, Baglietto L, Giles G, Southey M, Marmé F, Schneeweiss A, Sohn C, Burwinkel B, Yesilyurt BT, Neven P, Paridaens R, Wildiers H, Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Schott S, Bartram CR, Schmutzler RK, Cox A, Brock IW, Elliott G, Cross SS, Fasching PA, Schulz-Wendtland R, Ekici AB, Beckmann MW, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Dörk T, Schürmann P, Bremer M, Hillemanns P, Bogdanova NV, Antonenkova NN, Rogov YI, Karstens JH, Khusnutdinova E, Bermisheva M, Prokofieva D, Gancev S, Jakubowska A, Lubinski J, Jaworska K, Durda K, Nordestgaard BG, Bojesen SE, Lanng C, Mannermaa A, Kataja V, Kosma V-M, Hartikainen JM, Radice P, Peterlongo P, Manoukian S, Bernard L, Couch FJ, Olson JE, Wang X, Fredericksen Z, Grenaker Alnæs G, Kristensen V, Børresen-Dale A-L, Devilee P, Tollenaar RAEM, Seynaeve CM, Hooning MJ, García-Closas M, Chanock SJ, Lissowska J, Sherman ME, Hall P, Liu J, Czene K, Kang D, Yoo K-Y, Noh D-Y, Lindblom A, Margolin S, Dunning AM, Pharoah PDP, Easton DF, Guénel P, Brauch H.
11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast Cancer.
Human Mutation 2012; 33: 1123-1132.

Krämer HU, Müller H, Stegmaier C, Rothenbacher D, Raum E, Brenner H.
Type 2 diabetes mellitus and gender-specific risk for colorectal neoplasia.
European Journal of Epidemiology 2012; 27: 341-347.

Coté ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Aben KK, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, Brenner H, Duell EJ, Fabianova E, Field JK, Foretova L, Friis S, Harris CC, Holcatova I, Hong YC, Isla D, Janout V, Kiemeney LA, Kiyohara C, Lan Q, Lazarus P, Lissowska J, Le Marchand L, Mates D, Matsuo K, Mayordomo JI, McLaughlin JR, Morgenstern H, Müller H, Orlow I, Park BJ, Pinchev M, Raji OY, Rennert HS, Rudnai P, Seow A, Stucker I, Szeszenia-Dabrowska N, Dawn Teare M, Tjønneland A, Ugolini D, van der Heijden HF, Wichmann E, Wiencke JK, Woll PJ, Yang P, Zaridze D, Zhang ZF, Etzel CJ, Hung RJ.
Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium.
European Journal of Cancer 2012; 48: 1957-1968.

Maatouk I, Wild B, Herzog W, Wesche D, Schellberg D, Schöttker B, Müller H, Rothenbacher D, Stegmaier C, Brenner H.
Longitudinal predictors of health-related quality of life in middle-aged and older adults with hypertension: results of a population based study.
Journal of Hypertension 2012; 30: 1364-1372.

The Emerging Risk Factors Collaboration.*

C-reactive protein, fibrinogen, and cardiovascular disease prediction.
New England Journal of Medicine 2012; 367: 1310-1320.
* Participating investigators on behalf of the ESTHER Study: Brenner H (member of writing committee), Schöttker B, Müller H, Rothenbacher D).

Perna L, Haug U, Schöttker B, Müller H, Raum E, Jansen EHJM, Brenner H.
Public health implications of standardized 25-hydroxyvitamin D levels: a decrease in the prevalence of vitamin D deficiency among older women in Germany.
Preventive Medicine 2012; 55: 228-232.

The Emerging Risk Factors Collaboration.*

Adult height and the risk of cause-specific death and vascular morbidity in 1 million adults. International Journal of Epidemiology 2012; 41: 1419-1433. *Participating Investigators on behalf of the ESTHER Study: Brenner H, Schöttker B, Müller H, Rothenbacher D.


Warren H, Dudbridge F, Fletcher O, Orr N, Johnson N, Hopper JL, Apicella C, Southey MC, Mahmoodi M, Schmidt MK, Broeks A, Cornelissen S, Braaf LM, Muir K, Lophatananon A, Chaiwerawattana A, Wiangnon S, Fasching PA, Beckmann MW, Ekici AB, Schulz-Wendtland R, Sawyer EJ, Tomlinson I, Kerin MJ, Burwinkel B, Marme F, Schneeweiss A, Sohn C, Guenel P, Truong T, Laurent-Puig P, Mulot C, Bojesen SE, Nielsen SF, Flyger H, Nordestgaard BG, Milne RL, Benitez J, Ignacio Arias Perez J, Zamora MP, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Muller H, Arndt V, Langheinz A, Meindl A, Golatta M, Bartram CR, Schmutzler RK, Brauch H, Justenhoven C, Bruning T, Chang-Claude J, Wang-Gohrke S, Eilber U, Dork T, Schurmann P, Bremer M, Hillemanns P, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Bogdanova N, Antonenkova N, Rogov Y, Bermisheva M, Prokofyeva D, Zinnatullina G, Khusnutdinova E, Lindblom A, Margolin S, Mannermaa A, Kosma VM, Hartikainen JM, Kataja V, Chenevix-Trench G, Beesley J, Chen X, Lambrechts D, Smeets A, Paridaens R, Weltens C, Flesch-Janys D, Buck K, Behrens S, Peterlongo P, Bernard L, Manoukian S, Radice P, Couch FJ, Vachon CM, Wang X, Olsen JE, Giles GG, Baglietto L, McLean CA, Severi G, John EM, Miron A, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Mulligan AM, Weerasooriya N, Devilee P, Tollenaar RA, Martens JW, Seynaeve CM, Hooning MJ, Hollestelle A, Jager A, Tilanus-Linthorst MM, Hall P, Czene K, Jianjun L, Jingmei L, Cox A, Cross SS, Brock IW, Reed MW, Pharoah PD, Blows FM, Dunning AM, Ghoussaini M, Ashworth A, Swerdlow A, Jones M, Schoemaker MJ, Easton DF, Humphreys MK, Wang Q, Peto J, Dos Santos Silva I.

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.

Cancer Epidemiology, Biomarkers & Prevention 2012; 21: 1783-1791.


Schöttker B, Jansen EHJM, Haug U, Schomberg L, Köhrle J, Brenner H.

Standardization of misleading immunoassay based 25-hydroxyvitamin D levels with liquid chromatography tandem-mass spectrometry in a large cohort study.

PLoS One 2012; 7: e48774.


Saum K-U, Müller H, Stegmaier C, Hauer K, Raum E, Brenner H.

Development and evaluation of a modification of the Fried frailty criteria using population-independent cutpoints.

Journal of the American Geriatrics Society 2012; 60: 2110-2115.


Fox CS, Matsushita K, Woodward M, Bilo HJG, Chalmers J, Lambers Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen C-P, Nelson RG, on behalf of the CKD Prognosis Consortium (Investigators/Collaborators for the ESTHER study in the Chronic Kidney Disease Prognosis Consortium: Rothenbacher D, Brenner H, Müller H, Schöttker B).

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis.

Lancet 2012; 380: 1662-1673.


Mahmoodi BK, Matsushita K, Woodward M, Blankestijn PJ, Cirillo M, Ohkubo T, Rossing P, Sarnak MJ, Stengel B, Yamagishi K, Yamashita K, Zhang L, Coresh J, de Jong PE, MD2; Astor BC, for the Chronic Kidney Disease Prognosis Consortium (Investigators/Collaborators for the ESTHER study in the Chronic Kidney Disease Prognosis Consortium: Rothenbacher D, Brenner H, Müller H, Schöttker B).

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis.

Lancet 2012; 380; 1649-1661.


Breitling LP, Müller H, Stegmaier C, Kliegel M, Brenner H.

Association of prion protein with cognitive functioning in humans.

Experimental Gerontology 2012; 47: 919-924.


Hallan SI, Matsushita K, Sang Y, Mahmoodi BK, Black C, Ishani A, Kleefstra N, Naimark D, Roderick P, Tonelli M, Wetzels JFM, Astor BC, Gansevoort RT, Levin A, Wen C-P, Coresh J for the Chronic Kidney Disease Prognosis Consortium.*
Age and association of kidney measures with mortality and end-stage renal disease.

JAMA 2012; 308: 2349-2360.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Raum E,

Koenig W.

 


2011


Adamu MA, Weck MN, Rothenbacher D, Brenner H.
Incidence and risk factors for the development of chronic atrophic gastritis: five year follow-up of a population based cohort study.
International Journal of Cancer 2011; 128: 1652-1658.

Wild B, Lechner S, Herzog W, Maatouk I, Raum E, Müller H, Brenner H, Slaets J, Huyse F, Söllner W.
Reliable integrative assessment of health care needs in elderly persons - the INTERMED for the Elderly (IM-E).
Journal of Psychosomatic Research 2011; 70: 169-178.

Yang R, Dick M, Marme F, Schneeweiss A, Langheinz A, Hemminki K, Sutter C, Bugert P, Wappenschmidt B, Varon R, Schott S, Weber BHF, Niederacher D, Arnold N, Meindl A, Bartram CR, Schmutzler RK, Müller H, Arndt V, Brenner H, Sohn C, Burwinkel B.
Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk.
Breast Cancer Research and Treatment 2011; 127: 549-554.

The Emerging Risk Factors Collaboration.*
Diabetes mellitus, fasting glucose, and risk of cause-specific mortality.
New England Journal of Medicine 2011; 364: 829-841.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Breitling LP, Yang R, Korn B, Burwinkel B, Brenner H.
Tobacco smoking-related differential DNA methylation: 27k discovery and replication.
American Journal of Human Genetics 2011; 88: 450-457.

Herder C, Schoettker B, Rothenbacher D, Roden M, Kolb H, Müller H, Brenner H.
Interleukin-6 in the prediction of primary cardiovascular events in diabetes patients: results from the ESTHER study.
Atherosclerosis 2011; 216: 244-247.

Kote-Jarai Z, Al Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Canzian F, Riboli E, Key T, Gronberg H, Hunter DJ, Kraft P, J Thun MJ, Ingles S, Chanock S, Albanes D, Hayes RB, Neal DE, Hamdy FC, Donovan JL, Pharoah P, Schumacher F, Henderson BE, Stanford JL, Ostrander EA, Dalsgaard Sorensen K, Dörk T, Andriole G, Dickinson JL, Cybulski C, Lubinski J, Spurdle A, Clements JA, Chambers S, Aitken J, Gardiner F, Thibodeau SN, Schaid D, John EM, Maier C, Vogel W, Cooney KA, Park JY, Cannon-Albright L, Brenner H, Habuchi T, Zhang H-W, Lu Y-J, Kaneva R, Muir K, Benlloch S, Leongamornlert DA, Saunders EJ, Tymrakiewicz M, Mahmud N, Guy M, O’Brien LT, Wilkinson RA, Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, van As N, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL, English D, Wahlfors T, Tammela TLJ, Klarskov P, Nordestgaard BG, Røder MA, Tybjærg-Hansen A, Bojesen SE, Travis R, Campa D, Kaaks R, Wiklund F, Aly M, Lindstrom S, Diver WR, Gapstur S , Stern MC, Corral R, Virtamo J, Cox A, Haiman CA, Le Marchand L, FitzGerald L, Kolb S, Kwon EM, Karyadi DM, Falck Orntoft T, Borre M, Meyer A, Serth J, Yeager M, Berndt SI, Marthick JR, Patterson B, Wokolorczyk D, Batra J, Lose F, McDonnell SK , Joshi AD, Shahabi A , Rinckleb AE, Ray A, Sellers TA, Lin H-Y, Stephenson RA, Farnham J, Müller H, Rothenbacher D, Tsuchiya N, Narita S, Cao G-W , Slavov C, Mitev V, The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons’ Section of Oncology, The UK ProtecT Study Collaborators, The PRACTICAL Consortium,
Easton DF, Eeles RA.
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.
Nature Genetics 2011; 43: 785-791. doi: 10.1038/ng.882.

Breitling LP, Müller H, Illig T, Rujescu D, Winterer G, Dahmen N, Nitz B, Raum E, Rothenbacher D, Brenner H.
Dopamine-related genes and spontaneous smoking cessation in ever-heavy smokers.
Pharmacogenomics 2011; 12: 1099-1106.

Nicolotti N, Chuang S-C, Cadoni G, Arzani D, Petrelli L, Bosetti C, Brenner H, Hosono S, La Vecchia C, Matsuo K, Müller H, Muscat J, Paludetti G, Ricciardi G, Boffetta P,
Hashibe M, Boccia S.
Recreational physical activity and risk of head and neck cancer: a pooled analysis within the International Head and Neck Cancer Epidemiology (INHANCE) Consortium.
European Journal of Epidemiology 2011; 26: 619-628.

Milne RL, Goode EL, Garcia-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N, Zamora MP, Ignacio Arias Perez J, Benítez J, Dork T, Schurmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliott G, Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC, Huang CS, Hou MF, Nordestgaard BG, Bojesen SE, Lanng C, Grenaker Alnaes G, Kristensen V, Borresen-Dale AL, Hopper JL, Dite GS, Apicella C, Southey MC, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Chang-Claude J, Wang-Gohrke S, Radice P, Peterlongo P, Manoukian S, Barile M, Giles GG, Baglietto L, John EM, Miron A, Chanock SJ, Lissowska J, Sherman ME, Figueroa JD, Bogdanova NV, Antonenkova NN, Zalutsky IV, Rogov YI, Fasching PA, Bayer CM, Ekici AB, Beckmann MW, Brenner H, Muller H, Arndt V, Stegmaier C, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Meindl A, Heil J, Bartram CR, Schmutzler RK, Thomas GD, Hoover RN, Fletcher O, Gibson LJ, Dos Santos Silva I, Peto J, Nickels S, Flesch-Janys D, Anton-Culver H, Ziogas A, Sawyer E, Tomlinson I, Kerin M, Miller N, Schmidt MK, Broeks A, Vant Veer LJ, Tollenaar RA, Pharoah PD, Dunning AM, Pooley KA, Marmee F, Schneeweiss A, Sohn C, Burwinkel B, Jakubowska A, Lubinski J, Jaworska K, Durda K, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Kraft P, Lindström S, Chen X, Beesley J, Hamann U, Harth V, Justenhoven C, Winqvist R, Pylkas K, Jukkola-Vuorinen A, Grip M, Hooning M, Hollestelle A, Oldenburg RA, Tilanus-Linthorst M, Khusnutdinova E, Bermisheva M, Prokofieva D, Farahtdinova A, Olson JE, Wang X, Humphreys MK, Wang Q, Chenevix-Trench G, Easton DF.
Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer.
Cancer Epidemiology, Biomarkers & Prevention 2011; 20: 2222-2231.

Frank B, Müller H, Weck MN, Klopp N, Illig T, Raum E, Brenner H.
DNA repair gene polymorphisms and risk of chronic atrophic gastritis: a case-control study.
BMC Cancer 2011; 11: 440.

Figueroa JD, Garcia-Closas M, Humphreys M, Platte R, Hopper JL, Southey MC, Apicella C, Hammet F, Schmidt MK, Broeks A, Tollenaar RA, Van 't Veer LJ, Fasching PA, Beckmann MW, Ekici AB, Strick R, Peto J, Dos Santos Silva I, Fletcher O, Johnson N, Sawyer E, Tomlinson I, Kerin M, Burwinkel B, Marme F, Schneeweiss A, Sohn C, Bojesen S, Flyger H, Nordestgaard BG, Benítez J, Milne R, Arias JI, Zamora MP, Brenner H, Müller H, Arndt V, Rahman N, Turnbull C, Seal S, Renwick A, Brauch H, Justenhoven C, Brüningv T; The GENICA network, Chang-Claude J, Hein R, Wang-Gohrke S, Dörk T, Schürmann P, Bremer M, Hillemanns P, Nevanlinna H, Heikkinen T, Aittomäki K, Blomqvist C, Bogdanova N, Antonenkovav N, Rogov Y, Karstens JH, Bermisheva M, Prokofyeva D, Gancev SH, .Khusnutdinova E, Lindblom A, Margolin S, Chenevix-Trench G, Beesley J, Chen X; kConFab AOCS Management Group, Mannermaa A, Kosma VM, Soini Y, Kataja V, Lambrechts D, Yesilyurt BT, Chrisiaens MR, Peeters S, Radice P, Peterlongo P, Manoukian S, Barile M, Couch F, Lee AM, Diasio R, Wang X, Giles GG, Severi G, Baglietto L, Maclean C, Offit K, Robson M, Joseph V, Gaudet M, John EM, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis I, Knight JA, Mulligan AM, O'Malley FP, Brinton L, Sherman M, Lissowska J, Chanock S, Hooning M, Martens JW, van den Ouweland AM, Collée JM, Hall P, Czene K, Cox A, Brock IW, Reed MW, Cross SS, Pharoah P, Dunning AM, Kang D, Yoo KY, Noh DY, Ahn SH, Jakubowska A, Lubinski J, Jaworska K, Durda K, Sangrajrang S, Gaborieau V, .Brennan P, McKay J, Shen CY, Ding SL, Hsu HM, Yu JC, Anton-Culver H, Ziogas A, .Ashworth A, Swerdlow A, Jones M, Orr N, Trentham-Dietz A, Egan K, Newcomb P, Titus-.Ernstoff L, Easton D, Spurdle AB.
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.
Human Molecular Genetics 2011; 20: 4693-4706.

Schöttker B, Raum E, Rothenbacher D, Müller H, Brenner H.
Prognostic value of haemoglobin A1c and fasting plasma glucose for incident diabetes and implications for screening.
European Journal of Epidemiology 2011; 26: 779-787.

 


2010


The Emerging Risk Factors Collaboration.*
C-reactive protein concentration and the risk of coronary heart disease, stroke and mortality.
Lancet 2010; 375: 132-140.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H.
Alcohol consumption, serum gamma-glutamyltransferase and Helicobacter pylori infection in a population-based study among 9733 older adults.
Annals of Epidemiology 2010; 20: 122-128.

Gao L, Weck MN, Raum E, Stegmaier C, Rothenbacher D, Brenner H.
Sibship size, Helicobacter pylori infection and chronic atrophic gastritis: a population-based study among 9444 older adults from Germany.
International Journal of Epidemiology 2010; 39: 129-134.

Mobascher A, Rujescu D, Mittelstraß K, Giegling I, Lamina C, Nitz B, Brenner H, Fehr C, Breitling LP, Gallinat J, Rothenbacher D, Raum E, Müller H, Ruppert A, Hartmann AM, Möller HJ, Gal A, Gieger C, Wichmann HE, Illig T, Dahmen N, Winterer G.
Association of a variant in the muscarinic acetylcholine receptor 2 gene (CHRM2) with nicotine addiction.
American Journal of Medical Genetics Part B - Neuropsychiatric Genetics 2010; 153B: 684-690.

Breitling LP, Müller H, Raum E, Rothenbacher D, Brenner H.
Low-to-moderate alcohol consumption and smoking cessation rates: retrospective analysis of 4576 elderly ever-smokers.
Drug Alcohol Depend 2010; 108: 122-129.

Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration.*
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.
Lancet 2010; 375: 1634-1639.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Chronic Kidney Disease Prognosis Consortium.*
Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.
Lancet 2010; 375: 2073-2081.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Raum E,

Koenig W.

Zhang Q-L, Brenner H, Koenig W, Rothenbacher D.
Prognostic value of chronic kidney disease in patients with coronary heart disease: role of estimating equations.
Atherosclerosis 2010; 211: 342-347.

The Emerging Risk Factors Collaboration.*
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.
Lancet 2010; 375: 2215-2222.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Truong T, Hung RJ, Amos CI, Wu X, Bickeboeller H, Rosenberger A, Sauter W, Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, Wrensch M, Hansen H, Kelsey KT, Matsuo K, Tajima K, Schwartz A, Wenzlaff A, Seow A, Ying C, Staratschek-Jox A, Nuernberg P, Stoelben E, Wolf J, Lazarus P, Muscat JE, Gallagher C, Zienolddiny S, Haugen A, van der Heijden HFM, Kiemeney LA, Isla D, Mayordomo JI, Rafnar T, Stefansson K, Zhang ZF, Chang SC, Kim JH, Hong YC, Duell EJ, Andrew AS, Lejbkowicz F, Rennert G, Mueller H, Brenner H, Le Marchand L, Benhamou S, Bouchardy C, Teare MD, Xue X, McLaughlin J, Liu G, McKay JD, Brennan P, Spitz M.
Replication of lung cancer susceptibility loci at chromosome 15q25, 5p15, and 6p21: A pooled analysis from the International Lung Cancer Consortium.
Journal of the National Cancer Institute 2010; 102: 959-971.

Gao L, Weck MN, Rothenbacher D, Brenner H.
Body mass index, chronic atrophic gastritis and heartburn: a population-based study among 8936 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2010; 32: 296-302.

Gao L, Weck MN, Nieters A, Brenner H.
Grb2-associated binder 1 (Gab1) genetic polymorphism, Helicobacter pylori infection and chronic atrophic gastritis among older adults from Germany.
Molecular Carcinogenesis 2010; 49: 869-873.

Breitling LP, Wolf M, Müller H, Raum E, Kliegel M, Brenner H.
Large-scale application of a telephone-based test of cognitive functioning in older adults.
Dementia and Geriatric Cognitive Disorders 2010; 30: 309-316.

Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J and The Emerging Risk Factors Collaboration.*
Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies.
International Journal of Epidemiology 2010; 39: 1345-1359.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Winterer G, Mittelstraß K, Giegling I, Lamina C, Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat J, Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller H-J, Gieger C, Wichmann H-E, Illig T, Dahmen N, Rujescu D.
Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 2010; 153B: 1448-1458.

 


2009


Zhang Q-L, Koenig W, Raum E, Stegmaier C, Brenner H, Rothenbacher D.
Epidemiology of chronic kidney disease: results from a population of older adults in Germany.
Preventive Medicine 2009; 48: 122-127.

Breitling LP, Raum E, Müller H, Rothenbacher D, Brenner H.
Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase.
Hepatology 2009; 49: 802-808.

Gao L, Weck MN, Michel A, Pawlita M, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15 Helicobacter pylori proteins measured by multiple serology.
Cancer Research 2009; 69: 2973-2980.

Breitling LP, Dahmen N, Mittelstraß K, Illig T, Rujescu D, Raum E, Winterer G, Brenner H.
Smoking cessation and variations in nicotinic acetylcholine receptor subunits a-5, a-3 and b-4 genes.
Biological Psychiatry 2009; 65: 691-695.

Müller H, Raum E, Rothenbacher D, Stegmaier C, Brenner H.
Association of diabetes and body mass index with levels of prostate-specific antigen: Implications for correction of prostate-specific antigen cut-off values?
Cancer Epidemiology, Biomarkers & Prevention 2009; 18: 1350-1356.

Weck MN, Gao L, Brenner H.
Helicobacter pylori infection and chronic atrophic gastritis: associations according to severity of disease.
Epidemiology 2009; 20: 569-574.

Widschwendter M, Lichtenberg-Frate H, Hasenbrink G, Schwarzer S, Dawnay A, Lam A, Menon U, Apostolidou S, Raum E, Stegmaier C, Jacobs IJ, Brenner H.
Serum oestrogen receptor alpha- and beta-bioactivity are independently associated with breast cancer - a proof of principle study.
British Journal of Cancer 2009; 101: 160-165.

The Emerging Risk Factors Collaboration.*

Lipoprotein(a) concentration and the risk of coronary heart disease, stroke and nonvascular mortality. Individual data analysis of 126,634 participants from 36 prospective studies. JAMA 2009; 302: 412-423.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Gao L, Michel A, Weck MN, Arndt V, Pawlita M, Brenner H.
Helicobacter pylori infection and gastric cancer risk: evaluation of 15 Helicobacter pylori proteins determined by novel multiplex serology.
Cancer Research 2009; 69: 6164-6160.

Breitling LP, Dahmen N, Illig T, Rujescu D, Nitz B, Raum E, Winterer G, Rothenbacher D, Brenner H.
Variants in COMT and spontaneous smoking cessation: retrospective cohort analysis of 925 cessation events.
Pharmacogenetics & Genomics 2009; 19: 657-659.

Breitling LP, Dahmen N, Mittelstraß K, Rujescu D, Gallinat J, Fehr C, Giegling I, Lamina C, Illig T, Müller H, Raum E, Rothenbacher D, Wichmann HE, Brenner H, Winterer G.
Association of nicotinic acetylcholine receptor subunit alpha-4 polymorphisms with nicotine dependence in 5500 Germans.
The Pharmacogenomics Journal 2009; 9: 219-224.

Gao L, Weck MN, Nieters A, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15 Helicobacter pylori proteins measured by multiple serology.
European Journal of Cancer; 69: 2973-2980.

Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H.

Alcohol consumption and chronic atrophic gastritis: population-based study among 9444 older adults from Germany.

International Journal of Cancer 2009; 125:2918-2922.


The Emerging Risk Factors Collaboration.*

Major lipids, apolipoproteins and risk of vascular disease.

JAMA 2009; 302: 1993-2000.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

 


2008


Raum E, Lietzau S, Stegmaier C, Brenner H., Rothenbacher D.
For the majority of patients with diabetes blood pressure and lipid management is not in line with recommendations. Results from a large population-based cohort in Germany.
Pharmacoepidemiology and Drug Safety 2008; 17: 485-494.

Widschwendter M, Apostolidou S, Raum E, Rothenbacher D, Fiegl H, Menon U, Stegmaier C, Jacobs IJ, Brenner H.
Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study.
PloS ONE 2008; 3: e2656.

Müller H, Haug U, Rothenbacher D, Stegmaier C, Brenner H.
Evaluation of serum and urine MRP-14 as marker for early detection of prostate cancer.
Journal of Urology 2008; 180: 1309-1313.

 


2007


Haug U, Hillebrand T, Bendzko P, Löw M, Rothenbacher D, Stegmaier C, Brenner H.
Mutant-enriched PCR and allele-specific hybridization reaction to detect K-ras-mutations in stool DNA: High prevalence in a large sample of older adults.
Clinical Chemistry 2007; 53: 787-790.

Wolkewitz M, Rothenbacher D, Löw M, Stegmaier C, Ziegler H, Radulescu M, Brenner H, Diepgen TL.
Lifetime prevalence of self-reported atopic diseases in a population-based sample of elderly: results of the ESTHER-study.
British Journal of Dermatology 2007; 156: 693-697.

Haug U, Rothenbacher D, Wente MN, Seiler CM, Stegmaier C, Brenner H.
Tumor M2-PK as a stool marker for colorectal cancer: comparative analysis in a large sample of unselected older adults versus colorectal cancer patients.
British Journal of Cancer 2007; 96: 1329-1334.

Raum E, Rothenbacher D, Ziegler H, Brenner H.
Heavy physical activity – risk or protective factor for cardiovascular disease? A life course perspective.
Annals of Epidemiology 2007; 17: 417-424.

Weck MN, Stegmaier C, Rothenbacher D, Brenner H.
Epidemiology of chronic atrophic gastritis: population based study among 9,444 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2007; 26: 879-887.

Brenner H, Rothenbacher D, Weck MN.
Epidemiologic findings on serologically defined chronic atrophic gastritis strongly depend on the choice of the cutoff-value.
International Journal of Cancer 2007; 121: 2782-2786.

Raum E, Rothenbacher D, Löw M, Stegmaier C, Ziegler H, Brenner H.
Changes of cardiovascular risk factors and their implications in subsequent birth cohorts of older adults in Germany: a life course approach.
European Journal of Cardiovascular Prevention and Rehabilitation 2007; 14: 809-814.

 


2006


Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study.
Journal of Clinical Epidemiology 2006; 59: 82-89.

Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The impact of body weight on smoking cessation in German adults.
Preventive Medicine 2006; 42: 109-113.

Wang H, Rothenbacher D, Löw M, Stegmaier C, Brenner H, Diepgen TL.
Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung und colorectum.
International Journal of Cancer 2006; 119: 695-701.

 


2004


Löw M, Stegmaier C, Ziegler H, Rothenbacher D, Brenner H.
Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und optimierten Therapie chronischer Erkrankungen in der älteren Bevölkerung (ESTHER-Studie).
Deutsche Medizinische Wochenschrift 2004; 129: 2643-2647.

Bergk V, Gasse C, Rothenbacher D, Loew M, Brenner H, Haefeli WE.
Drug interactions in primary care: impact of a new algorithm on risk determination.
Clinical Pharmacology and Therapeutics 2004; 76: 85-96.

 

 

 

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