Publikationen

2010

The Emerging Risk Factors Collaboration.*
C-reactive protein concentration and the risk of coronary heart disease, stroke and mortality.
Lancet 2010; 375: 132-140.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Gao L, Weck M.N., Stegmaier C, Rothenbacher D, Brenner H.
Alcohol consumption, serum gamma-glutamyltransferase and Helicobacter pylori infection in a population-based study among 9733 older adults.
Annals of Epidemiology 2010; 20: 122-128.

Gao L, Weck MN, Raum E, Stegmaier C, Rothenbacher D, Brenner H.
Sibship size, Helicobacter pylori infection and chronic atrophic gastritis: a population-based study among 9444 older adults from Germany.
International Journal of Epidemiology 2010; 39: 129-134.

Mobascher A, Rujescu D, Mittelstraß K, Giegling I, Lamina C, Nitz B, Brenner H, Fehr C, Breitling LP, Gallinat J, Rothenbacher D, Raum E, Müller H, Ruppert A, Hartmann AM, Möller HJ, Gal A, Gieger C, Wichmann HE, Illig T, Dahmen N, Winterer G.
Association of a variant in the muscarinic acetylcholine receptor 2 gene (CHRM2) with nicotine addiction.
American Journal of Medical Genetics Part B - Neuropsychiatric Genetics 2010; 153B: 684-690.

Breitling LP, Müller H, Raum E, Rothenbacher D, Brenner H.
Low-to-moderate alcohol consumption and smoking cessation rates: retrospective analysis of 4576 elderly ever-smokers.
Drug Alcohol Depend 2010; 108: 122-129.

Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration.*
Triglyceride-mediated pathways and coronary disease:collaborative analysis of 101 studies.
Lancet 2010; 375: 1634-1639.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Chronic Kidney Disease Prognosis Consortium.*
Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.
Lancet 2010; 375: 2073-2081.
* Authors on behalf of the ESTHER study: Rothenbacher D, Brenner H, Raum E, Koenig W.

Zhang Q-L, Brenner H, Koenig W, Rothenbacher D.
Prognostic value of chronic kidney disease in patients with coronary heart disease: role of estimating equations.
Atherosclerosis 2010; 211: 342-347.

The Emerging Risk Factors Collaboration.*
Diabetes mellitus, fasting blood glucose concentration , and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.
Lancet 2010; 375: 2215-2222.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Truong T, Hung RJ, Amos CI, Wu X, Bickeboeller H, Rosenberger A, Sauter W, Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, Wrensch M, Hansen H, Kelsey KT, Matsuo K, Tajima K, Schwartz A, Wenzlaff A, Seow A, Ying C, Staratschek-Jox A, Nuernberg P, Stoelben E, Wolf J, Lazarus P, Muscat JE, Gallagher C, Zienolddiny S, Haugen A, van der Heijden HFM, Kiemeney LA, Isla D, Mayordomo JI, Rafnar T, Stefansson K, Zhang ZF, Chang SC, Kim JH, Hong YC, Duell EJ, Andrew AS, Lejbkowicz F, Rennert G, Mueller H, Brenner H, Le Marchand L, Benhamou S, Bouchardy C, Teare MD, Xue X, McLaughlin J, Liu G, McKay JD, Brennan P, Spitz M.
Replication of lung cancer susceptibility loci at chromosome 15q25, 5p15, and 6p21: A pooled analysis from the International Lung Cancer Consortium.
Journal of the National Cancer Institute 2010; 102: 959-971.

Gao L, Weck MN, Rothenbacher D, Brenner H.
Body mass index, chronic atrophic gastritis and heartburn: a population-based study among 8936 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2010; 32: 296-302.

Gao L, Weck MN, Nieters A, Brenner H.
Grb2-associated binder 1 (Gab1) genetic polymorphism, Helicobacter pylori infection and chronic atrophic gastritis among older adults from Germany.
Molecular Carcinogenesis 2010; 49: 869-873.

Breitling LP, Wolf M, Müller H, Raum E, Kliegel M, Brenner H.
Large-scale application of a telephone-based test of cognitive functioning in older adults.
Dementia and Geriatric Cognitive Disorders 2010; 30: 309-316.

Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J and The Emerging Risk Factors Collaboration *
Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies.
International Journal of Epidemiology 2010; 39: 1345-1359.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

The Emerging Risk Factors Collaboration.*
Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies.
International Journal of Epidemiology (im Druck).
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Adamu MA, Weck MN, Rothenbacher D, Brenner H.
Incidence and risk factors for the development of chronic atrophic gastritis: five year follow-up of a population based cohort study.
International Journal of Cancer (im Druck).

Winterer G, Mittelstraß K, Giegling I, Lamina C, Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat J, Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller H-J, Gieger C, Wichmann H-E, Illig T, Dahmen N, Rujescu D.
Risk gene variantsfor nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.
Neuropsychiatric Genetics (im Druck).

Wild B, Lechner S, Herzog W, Maatouk I, Raum E, Müller H, Brenner H, Slaets J, Huyse F, Söllner W.
Reliable integrative assessment of health care needs in elderly persons - the INTERMED for the Elderly (IM-E).
Journal of Psychosomatic Research (im Druck).

Rongxi Y, Dick M, Marme F, Schneeweiss A, Langheinz A, Hemminki K, Sutter C, Bugert P, Wappenschmidt B, Varon R, Schott S, Weber BHF, Niederacher D, Arnold N, Meindl A, Bartram CR, Schmutzler RK, Müller H, Arndt V, Brenner H, Sohn C, Burwinkel B.
Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk.
Breast Cancer Research and Treatment (im Druck).

2009

Zhang Q-L, Koenig W, Raum E, Stegmaier C, Brenner H, Rothenbacher D.
Epidemiology of chronic kidney disease: results from a population of older adults in Germany.
Preventive Medicine 2009; 48: 122-127.

Breitling LP, Raum E, Müller H, Rothenbacher D, Brenner H.
Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase.
Hepatology 2009; 49: 802-808.

Gao L, Weck MN, Michel A, Pawlita M, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15 Helicobacter pylori proteins measured by multiple serology.
Cancer Research 2009; 69: 2973-2980.

Breitling LP, Dahmen N, Mittelstraß K, Illig T, Rujescu D, Raum E, Winterer G, Brenner H.
Smoking cessation and variations in nicotinic acetylcholine receptor subunits a-5, a-3 and b-4 genes.
Biological Psychiatry 2009; 65: 691-695.

Müller H, Raum E, Rothenbacher D, Stegmaier C, Brenner H.
Association of diabetes and body mass index with levels of prostate-specific antigen: Implications for correction of prostate-specific antigen cut-off values?
Cancer Epidemiology, Biomarkers & Prevention 2009; 18: 1350-1356.

Weck MN, Gao L, Brenner H.
Helicobacter pylori infection and chronic atrophic gastritis: associations according to severity of disease.
Epidemiology 2009; 20: 569-574.

Widschwendter M, Lichtenberg-Frate H, Hasenbrink G, Schwarzer S, Dawnay A, Lam A, Menon U, Apostolidou S, Raum E, Stegmaier C, Jacobs IJ, Brenner H.
Serum oestrogen receptor alpha- and beta-bioactivity are independently associated with breast cancer - a proof of principle study.
British Journal of Cancer 2009; 101: 160-165.

The Emerging Risk Factors Collaboration.* Lipoprotein(a) concentration and the risk of coronary heart disease, stroke and nonvascular mortality. Individual data analysis of 126,634 participants from 36 prospective studies. JAMA 2009; 302: 412-423.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

Gao L, Michel A, Weck MN, Arndt V, Pawlita M, Brenner H.
Helicobacter pylori infection and gastric cancer risk: evaluation of 15 Helicobacter pylori proteins determined by novel multiplex serology.
Cancer Research 2009; 69: 6164-6160.

Breitling LP, Dahmen N, Illig T, Rujescu D, Nitz B, Raum E, Winterer G, Rothenbacher D, Brenner H.
Variants in COMT and spontaneous smoking cessation: retrospective cohort analysis of 925 cessation events.
Pharmacogenetics & Genomics 2009; 19: 657-659.

Breitling LP, Dahmen N, Mittelstraß K, Rujescu D, Gallinat J, Fehr C, Giegling I, Lamina C, Illig T, Müller H, Raum E, Rothenbacher D, Wichmann HE, Brenner H, Winterer G.
Association of nicotinic acetylcholine receptor subunit alpha-4 polymorphisms with nicotine dependence in 5500 Germans.
The Pharmacogenomics Journal 2009; 9: 219-224.

Gao L, Weck MN, Nieters A, Brenner H.
Association between chronic atrophic gastritis and serum antibodies to 15 Helicobacter pylori proteins measured by multiple serology.
European Journal of Cancer; 69: 2973-2980.

Gao L, Weck MN, Stegmaier C, Rothenbacher D, Brenner H. Alcohol consumption and chronic atrophic gastritis: population-based study among 9444 older adults from Germany. International Journal of Cancer 2009; 125:2918-2922.

The Emerging Risk Factors Collaboration.* Major lipids, apolipoproteins and risk of vascular disease. JAMA 2009; 302: 1993-2000.
* Authors on behalf of the ESTHER study: Brenner H, Raum E, Müller H, Rothenbacher D.

2008

Raum E, Lietzau S, Stegmaier C, Brenner H., Rothenbacher D.
For the majority of patients with diabetes blood pressure and lipid management is not in line with recommendations. Results from a large population-based cohort in Germany.
Pharmacoepidemiology and Drug Safety 2008; 17: 485-494.

Widschwendter M, Apostolidou S, Raum E, Rothenbacher D, Fiegl H, Menon U, Stegmaier C, Jacobs IJ, Brenner H.
Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study.
PloS ONE 2008; 3: e2656.

Müller H, Haug U, Rothenbacher D, Stegmaier C, Brenner H.
Evaluation of serum and urine MRP-14 as marker for early detection of prostate cancer.
Journal of Urology 2008; 180: 1309-1313.

2007

Haug U, Hillebrand T, Bendzko P, Löw M, Rothenbacher D, Stegmaier C, Brenner H.
Mutant-enriched PCR and allele-specific hybridization reaction to detect K-ras-mutations in stool DNA: High prevalence in a large sample of older adults.
Clinical Chemistry 2007; 53: 787-790.

Wolkewitz M, Rothenbacher D, Löw M, Stegmaier C, Ziegler H, Radulescu M, Brenner H, Diepgen TL.
Lifetime prevalence of self-reported atopic diseases in a population-based sample of elderly: results of the ESTHER-study.
British Journal of Dermatology 2007; 156: 693-697.

Haug U, Rothenbacher D, Wente MN, Seiler CM, Stegmaier C, Brenner H.
Tumor M2-PK as a stool marker for colorectal cancer: comparative analysis in a large sample of unselected older adults versus colorectal cancer patients.
British Journal of Cancer 2007; 96: 1329-1334.

Raum E, Rothenbacher D, Ziegler H, Brenner H.
Heavy physical activity – risk or protective factor for cardiovascular disease? A life course perspective.
Annals of Epidemiology 2007; 17: 417-424.

Weck MN, Stegmaier C, Rothenbacher D, Brenner H.
Epidemiology of chronic atrophic gastritis: population based study among 9,444 older adults from Germany.
Alimentary Pharmacology & Therapeutics 2007; 26: 879-887.

Brenner H, Rothenbacher D, Weck MN.
Epidemiologic findings on serologically defined chronic atrophic gastritis strongly depend on the choice of the cutoff-value.
International Journal of Cancer 2007; 121: 2782-2786.

Raum E, Rothenbacher D, Löw M, Stegmaier C, Ziegler H, Brenner H.
Changes of cardiovascular risk factors and their implications in subsequent birth cohorts of older adults in Germany: a life course approach.
European Journal of Cardiovascular Prevention and Rehabilitation 2007; 14: 809-814.

2006

Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study.
Journal of Clinical Epidemiology 2006; 59: 82-89.

Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H.
The impact of body weight on smoking cessation in German adults.
Preventive Medicine 2006; 42: 109-113.

Wang H, Rothenbacher D, Löw M, Stegmaier C, Brenner H, Diepgen TL.
Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung und colorectum.
International Journal of Cancer 2006; 119: 695-701.

2004

Löw M, Stegmaier C, Ziegler H, Rothenbacher D, Brenner H.
Epidemiologische Studie zu Chancen der Verhütung, Früherkennung und optimierten Therapie chronischer Erkrankungen in der älteren Bevölkerung (ESTHER-Studie).
Deutsche Medizinische Wochenschrift 2004; 129: 2643-2647.

Bergk V, Gasse C, Rothenbacher D, Loew M, Brenner H, Haefeli WE.
Drug interactions in primary care: impact of a new algorithm on risk determination.
Clinical Pharmacology and Therapeutics 2004; 76: 85-96.